• 제목/요약/키워드: Laboratory Safety

검색결과 2,264건 처리시간 0.026초

A Study of Structural Analysis Simulation for Squat Exercise Foot Plate (스쿼트운동장치의 풋플레이트 구조해석에 관한 연구)

  • Jung, Byung-Geun;Kim, Ji-won;Jeong, Byeong-Ho
    • Journal of the Korea Convergence Society
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    • 제8권9호
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    • pp.365-372
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    • 2017
  • Squat exercise is one of the important free weight exercises that can safely and effectively expect the athletic performance by establishing the rationale. Therefore, it is necessary to study the side effects caused by incorrect exercise, scientific countermeasures and to develop a exercise estimation model. It is effective and accurate to use a variety of assistive devices to calibrate athletic posture. The issues of the structural analysis for designing a foot plate for squat exercise is to model the behavior by the dynamic behavior. It should be consider that the center of gravity of each segmented body is different when the maximum load is applied. It is applied to complete system design through simulation method with kinematic dynamic, ground reaction force and load analysis for the free weight exercise equipment, VR device, and safety foot plate. In this paper, the authors propose the design method for the vertical load distribution applied in the design of the foot plate used for the squat exercise mechanism, and based on these results, design make the more safe and reliable free weight exercise equipment system.

A Study on the Interference of HF Maritime Mobile Telecommunication by the PLC (전력선통신이 단파대 해상이동통신에 미치는 영향에 관한 연구)

  • Kim Jeong-nyun;Choi Jo-cheon;Jo Hag-hyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • 제10권2호
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    • pp.250-256
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    • 2006
  • The revision of radio waves act, which took effect on July 1,2005, widened the bandwidth of PLC from $9kHz{\sim}450kHz$ to $9kHz{\sim}30MHz$. This high upper limit of frequency may cause the interference in HF wireless communications. From this point of view, the goal of this research is to suggest the estimation method of whether-or-not the interference occurs and furthermore offer countermeasures to avoid it hereafter. Ministry of Information and Communication Radio Research Laboratory(MIC-RRL)has been researching for the interference and devoting themselves to turn out how much it affects to HF wireless communications since the revision took effect. This research suggests some estimation methods with receivers, signal generators, or SINAD(Signal to Noise and Distortion) Meter which is so suitable for the RF environment that we can overcome the existing limit to the EMC environment. In addition, this research is focused on securing the environment for wireless communications by establishing the safety zone or suggesting the ways to prohibit the use of the bandwidth, which may cause serious interference, in order to minimize the effect of PLC on HF maritime mobile telecommunications.

Toxicity of Eun-bi San Pharmacopuncture Injection inthe Muscle of Rats

  • Lee, Jongcheol;Jeong, Hohyun;Cha, Eunhye;Park, Manyong;Choi, Sungyoul;Yook, Taehan;Song, InJa;Kim, Sungchul
    • Journal of Pharmacopuncture
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    • 제18권1호
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    • pp.63-71
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    • 2015
  • Objectives: This study was carried out to analyze the single-dose toxicity of Eun-Bi San pharmacopuncture injected into the muscle of Sprague-Dawley (SD) rats. Methods: All experiments were performed at Biotoxtech, an institution certified to conduct non-clinical studies under the Good Laboratory Practice (GLP) regulations. Six week old SD rats reared by ORIENTBIO were chosen for this pilot study. The reason SD rats were chosen is that they have been widely used in safety tests in the field of medicine, so the results can be easily compared with many other databases. The Eun-Bi San pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (KPI, K-GMP). The constituents of the Eun-Bi San pharmacopuncture are Angelicae gigantis radix, Strychni semen and Glycyrrhizae radix. These were extracted at low temperature and low pressure in an aseptic room at the KPI. Doses of Eun-Bi San pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. This study was performed under the approval of the Institutional Animal Ethics Committee of Biotoxtech Co., Ltd. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To determine if abnormalities existed in any organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The results of this study suggest that treatment with Eun-Bi San pharmacopuncture is relatively safe and that its clinical use may be beneficial. Further evaluations and studies on this subject will be needed to provide more concrete evidence in support of these conclusions.

Influence of soil organic matter and moisture on the persistence of the herbicide mefenacet in soils (제초제 Mefenacet의 토양 중 분해에 미치는 토양유기물과 토양수분에 의한 영향)

  • Kim, Sung-Min;Cho, Il-Kyu;Kyung, Kee-Sung;Lee, Jae-Koo
    • The Korean Journal of Pesticide Science
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    • 제7권3호
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    • pp.182-187
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    • 2003
  • In order to elucidate a degradation characteristics of herbicide mefenacet in soil, the persistence in soils was studied under laboratory conditions for $90\sim120$ days at $28^{\circ}C$. Mefenacet residues were determined from the two soils which pre-treated by sterilization and flooding, respectively. Non-sterilized upland soil was used as a control. When 70 days elapsed from application time, $55\sim63%$ of mefenacet applied were dissipated in control soils. However, $32\sim33%$ of mefenacet applied were dissipated in the sterilized soils and $33\sim35%$ was dissipated in the flooded soils. 까 lese results indicated that the degradation of mefenacet was assumed to be due to microorganism, especially aerobic microbes. In order to elucidate the influence of water content on the persistence of mefenacet in soil, water content in soils was adjusted to 20, 50, and 80% of the water-holding capacity(Field capacity, WHC). The half-life of mefenacet in soil containing 20% and 50% of WHC were 82 and 73 days, respectively, after incubation for 90 days. However, the half-life in soil containing 80% of WHC was shortened to 61 days. These results indicated that degradation of mefenacet in soil was influenced by the activity of soil microorganism, organic matter content and water content.

Effects of Fire Curtain and Forced Smoke Ventilation on Smoke Spread to Auditorium in Stage Fire of Theater (공연장 무대 화재 시 방화막과 강제 배연구가 객석으로의 연기 확산에 미치는 영향)

  • Kim, Jae Han;Kim, Duncan;Lee, Chi Young
    • Fire Science and Engineering
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    • 제31권5호
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    • pp.28-36
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    • 2017
  • In this work, the effects of fire curtain and forced smoke ventilation on smoke spread to auditorium in the stage fire of theater were investigated using the Fire Dynamics Simulator (FDS). For the stage of 31 m (Width)${\times}$34 m (Depth)${\times}$32 m (Height) in dimension, the fast growth fire condition with 10 MW of heat release rate was applied. The forced smoke ventilation was set based on the National Fire Safety Code (NFSC) and previous research. The gap distances between the fire curtain and proscenium wall was established to be 0 m and 0.5 m. When the fire curtain was attached completely to the proscenium wall without any gap, no smoke spread from the stage to the auditorium occurred, independent of forced smoke ventilation. When the gap distance between the fire curtain and proscenium wall was 0.5 m, the smoke layer in the stage descended to the lower height from the bottom than the case without the fire curtain, which was because the smoke spread to auditorium was impeded by the fire curtain. Under the same fire curtain condition, the case with the forced smoke ventilation led to decreasing the mass flow rate of outflow through the gap between the fire curtain and proscenium wall, as compared to the case without the forced smoke ventilation. Based on this study, it was confirmed that the fire curtain and forced smoke ventilation were the effective tools to hold down the smoke spread to the auditorium in the stage fire of theater.

Radon Measurement by Alpha Particle Track Method (Alpha 입자비적법(粒子飛跡法)에 의(依)한 Radon 측정(測定))

  • Kang, Yung-Ho;Park, Jang-Sick;Kim, Do-Sung
    • Journal of Radiation Protection and Research
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    • 제7권1호
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    • pp.17-22
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    • 1982
  • Measurement of the radon concentration close to the ground surface can be used in search of environmental radiation for human safety, exploration for uranium, premonitory signals from earthquakes. We can detect radons in soil gas by alpha particle track method using the plastic track detectors, cellulose nitrate (LR115-Type 2 and CA80-15, Kodak $Path\'{e}$) and CR-39. For present works, radon cups having these detectors were made in our laboratory and their conversion factor was determined. A typical conversion factor was $1tr/cm^2{\cdot}30days=1.2{\times}10^{-2}pCi/l$. In the radon cups, some of $CaSO_4$ were used as desiccant for reducing the moisture effects on plastic track detectors. With these radon cups, underground radon concentrations of Kyungpook area were measured. Average radon concentration in Daegu from Jan. 1981 to Feb. 1982 was 39.7pCi/l. From Aug. 1981 to Feb. 1982, average radon concentrations of Daegu, Angang, Kyungju, Pohang, Chungha, and Andong were 31.8pCi/l, 124.5pCi/l, 127.0pCi/l, 79.1pCi/l, 144.4pCi/l, and 70.9pCi/l, respectively. The results were compared with the environmental radiation measured by TLD method.

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Experimental analysis of geomorphic changes in weir downstream by behavior of alternate bar upstream (보 상류 교호사주의 거동에 따른 하류 지형변화에 대한 실험적 분석)

  • Lee, KyungSu;Jang, Chang-Lae;Kim, GiJung
    • Journal of Korea Water Resources Association
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    • 제52권spc2호
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    • pp.801-810
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    • 2019
  • This study analyzes the impact on geomorphic changes downstream due to alternate bars developed weir upstream through laboratory experiments. The disturbance, such as a spur in the side wall, of the flow at the inlet of the channel triggers the development of alternate bar upstream at the beginning of the experiment, and gradually moved downstream with keeping their shapes over time. The bed in the downstream of weir in the mid of channel scoured due to the scarcity of sediment inflow because weir upstream traps it. Moreover, bar migration speed decreases as the bars approaches to the weir with time. However, as time increases, the alternate bars upstream migrate over the weir, and sediment in the eroded bed of the weir downstream are deposited. The phase of the bar upstream changes oppositely after passing through the weir. The phase of the bar downstream changes rapidly as the shape of alternate bar is clear upstream, which is affected by the strong disturbance. The phase of bar changes, and the bar migration speed decreases gradually with time, and finally stopped due to forcing effects on the bar by the disturbance. The faster the reaction of alternate bar with a long spur, the larger the bar height formed downstream and the shorter the bar length. This means that the larger the forcing effect of bar, the more it affects the bar migration. In addition, although the size of the alternate bar increases over time, the bar doesn't migrate downstream and a forced bar is generated.

Sampling and Extraction Method for Environmental DNA (eDNA) in Freshwater Ecosystems (수생태계의 환경유전자(environmental DNA: eDNA) 채집 및 추출기술)

  • Kim, Keonhee;Ryu, Jeha;Hwang, Soon-jin
    • Korean Journal of Ecology and Environment
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    • 제54권3호
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    • pp.170-189
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    • 2021
  • Environmental DNA (eDNA) is a genetic material derived from organisms in various environments (water, soil, and air). eDNA has many advantages, such as high sensitivity, short investigation time, investigation safety, and accurate species identification. For this reason, it is used in various fields, such as biological monitoring and searching for harmful and endangered organisms. To collect eDNA from a freshwater ecosystem, it is necessary to consider the target organism and gene and a wide variety of items, such as on-site filtration and eDNA preservation methods. In particular, the method of collecting eDNA from the environment is directly related to the eDNA concentration, and when collecting eDNA using an appropriate collection method, accurate (good quality) analysis results can be obtained. In addition, in preserving and extracting eDNA collected from the freshwater ecosystem, when an accurate method is used, the concentration of eDNA distributed in the field can be accurately analyzed. Therefore, for researchers at the initial stage of eDNA research, the eDNA technology poses a difficult barrier to overcome. Thus, basic knowledge of eDNA surveys is necessary. In this study, we introduced sampling of eDNA and transport of sampled eDNA in aquatic ecosystems and extraction methods for eDNA in the laboratory. In addition, we introduced simpler and more efficient eDNA collection tools. On this basis, we hope that the eDNA technique could be more widely used to study aquatic ecosystems and help researchers who are starting to use the eDNA technique.

Effects of Unripe Rubus Coreanus Extract on Upper Body Obesity: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (미숙과 복분자 추출물의 상체비만 개선 효과: 무작위배정, 이중눈가림, 위약-대조 임상연구)

  • Ha, Ki Chan;Kim, Hye Mi;Baek, Hyang Im;Jeong, Da Young;Kim, Eun;Lee, Ki Hoon;Kim, Ha Rim;Kwon, Kang Beom;Kim, Sunoh;Lee, Jung Han
    • Journal of Korean Medicine Rehabilitation
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    • 제31권4호
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    • pp.117-127
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    • 2021
  • Objectives Previously, we demonstrated that a 5% ethanol extract of unripe Rubus coreanus (5-uRCK) and ellagic acid has hypocholesterolemic and antiobesity activity in high-fat diet-fed animals. Therefore, we conducted a clinical study on the anti-obesity effect of 5-uRCK in 140 Korean adults (aged 19-70 years, body mass index (BMI) ≥25 kg/m2). Methods The participants were randomly assigned to two groups and were administered the placebo (n=70) or 5-uRCK extract (800 mg, n=70) daily for 12 weeks. The subjects were instructed to maintain their usual dietary intake and normal physical activity. Anthropometrics, body composition (dual-energy X-ray absorptiometry), and blood parameters were compared between the two groups. Results Average body weight and BMI did not show any significant changes; however, changes in upper body fat mass between the two groups was significantly different, as determined using analysis of covariance adjusted for baseline of percent body fat and drinking units. Moreover, Although not significant, the trunk fat mass and percent trunk fat tended to decrease after 5-uRCK supplementation. There was no significant difference in other laboratory biomarkers between the two groups. All safety parameters were within normal ranges in the both group. Conclusions In the present study, 5-uRCK significantly reduced upper body fat in obese subjects after 12 weeks, which indicates that it may help improve android-type obesity. Furthermore, the supplement is safe and well tolerated.

A Study on Penetration Effect of Penetrating Hardener for Prevention of Scattering of Asbestos Building Materials (석면 건축자재의 비산 방지를 위한 침투성 경화제 침투 효과에 관한 연구)

  • Song, Tae-Hyeob;Park, Ji-Sun;Shin, Hyun-Gyoo
    • Journal of the Korean Recycled Construction Resources Institute
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    • 제6권4호
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    • pp.324-330
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    • 2018
  • In accordance with the amendment of the Industrial Safety and Health Act of 2007, Korea completely prohibited the import, distribution and manufacture of asbestos like Europe and Japan. Accordingly, the current problem of asbestos is the safe maintenance and disposal of asbestos construction material, the disposal of asbestos, and the final disposal of asbestos building materials. In the past, Korea used 100,000 tons of asbestos every year, and the building materials using it exceeded 1 million tons per year. These asbestos building materials continued to be used until 2006, and the Ministry predicted that these materials would continue to be maintained until 2044. When the permeable hardening agent is applied to the asbestos building material installed in the pre-pretreatment step for the harmless treatment of the asbestos waste and the dismantling is carried out, the scattering of the asbestos is suppressed in the disassembling step, detoxification treatment conditions can be improved. Therefore, permeable hardeners should be stably penetrated into asbestos building materials. In this study, it is suggested that pre - pretreatment methods for the harmlessization of waste asbestos building materials with medium density level can be presented. In order to efficiently perform pre - treatment for chemical harmlessness in the future, the mixing ratio of permeable hardener and middle water Optimization is the most important factor.