• Title/Summary/Keyword: LR1. KI1

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Effects of Electroacupuncture and Electrical Stimulation on VEGF Expression After Muscle Crush Injury in Rats (전침 자극과 전기 자극의 적용이 근육압좌손상이 유발된 흰쥐의 골격근 내 혈관내피성장인자 발현에 미치는 영향)

  • Kim, Min-Hee;Lee, Hyun-Min;Park, Eun-Se;Nam, Ki-Won;Kim, Jin-Sang
    • Physical Therapy Korea
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    • v.13 no.2
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    • pp.9-15
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    • 2006
  • Skeletal muscle injury occurs frequently in sports medicine and is the most general form of injury followed by physical impact. There are growth factors which conduct proliferation, differentiation, and synthesis of myogenic prodromal cells and regulate vascular generation for the continued survival of myocytes. The purpose of the present study was to confirm the effects of electroacupuncture (EA) and electrical stimulation (ES) on muscle recovery processes according to vascular endothelial growth factor (VEGF) expression. Eighteen Sprague-Dawley rats were separated into 2 experimental groups and a controlled group. All animals had suffered from crush damage in the extensor digitorum longus for 30 seconds and were killed 1, 3, and 7 days after injury. 30 Hz and 1 mA impulsion for 15 minutes was applied to the EA experimental groups Zusanli (ST36) and Taichong (LR3) using electroacupuncture and the same stimulation was applied to the ES group using an electrical node. Hematoxyline-Eosin staining and VEGF immunohistochemistry were used to ascertain the resulting muscle recovery. There were few morphological differences between the EA and ES groups, and both groups were observed to have tendencies to decrease atrophy as time passed. In the controlled group, gradually diminishing atrophy could be observed, but their forms were mostly disheveled. There were few differences in VEGF expression between the EA and ES groups, and tendencies to have an increased quantity of VEGF with the lapse of time were observed in both groups. In the controlled group, a little VEGF expression could be observed merely 7 days after injury. In conclusion, EA and ES contributed to muscle recovery processes and could be used for the treatment of muscle injury.

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The inhibition of Hypertension-related Response by $17\beta$-estradiol and the Increase of $17\beta$-estradiol Activity by Electrical Stimulation ($17\beta$-estradiol의 고혈압 유도반응 억제와 인체적용 전기자극의 $17\beta$-estradiol 활성 증가)

  • Kim, Jung-Hwan
    • The Journal of Korean Physical Therapy
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    • v.21 no.2
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    • pp.109-116
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    • 2009
  • Purpose: $17\beta$-estradiol is the most active endogenous estrogen, which is related to favorable changes in the plasma lipid profile, to relaxation of the coronary vessels, and to a decrease in platelet aggregation and vascular smooth muscle cell migration. However, although the beneficial effect of estrogens on plasma lipoproteins (ie, lowering low-density lipoprotein and increasing high-density lipoprotein cholesterol) contributes to cardiovascular protection, it does not fully account for the protective effect, particularly in the application of physical therapy, including low frequency electrical stimulation. Methods: The aim of this study was to demonstrate the inhibition of stressors, such as endothelin-1 (ET-1), serotonin (5-hydroxytryptamine, 5-HT), prostaglandin $F2\alpha$ ($PGF2\alpha$), and a protein kinase C (PKC) activator 12-deoxyphorbol 13-isobutyrate (DPB), induced isometric tension by $17\beta$-estradiol in vascular smooth muscle strips, respectively. In addition, the effects of low frequency electrical stimulation at the meridian points (CV-3, -4, Ki-12, SP-6, LR-3, BL-25, -28, -32, -52) on the indirect antihypertensive effect were examined by monitoring the changes in the serum $17\beta$-estradiol concentration in healthy volunteers. Results: Isometric tension analysis showed that the responses of inhibited tension by $17\beta$-estradiol were similar to the same stressors in rat aortic smooth muscle strips. Furthermore, although the continued amplitude modulation (AM) type of electrical stimulation was not increased significantly by electrical stimulation, the current of the frequency modulation (FM) type of low frequency electrical stimulation increased the serum $17\beta$-estradiol concentration in normal volunteers. Conclusion: These results, in part, suggest that $17\beta$-estradiol has the capacity to supress stressor-induced muscle tension, and electrical stimulation, particularly current of the FM type, has a modulatory effect on the sex steroid hormones, particularly $17\beta$-estradiol, in healthy volunteers.

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A Philological Study on the Pathology, Acupuncture and Moxibustion of Alopecia (탈발(脫髮)의 병인병기(病因病機) 및 침구치료(鍼灸治療)에 관한 문헌고찰)

  • Lee, Sang Hyun;Cho, Myoung Rae
    • Journal of Acupuncture Research
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    • v.32 no.2
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    • pp.35-57
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    • 2015
  • Objectives : The purpose of this study is to analyze literature on oriental medicine to investigate the pathology, acupuncture, and moxibustion therapy applicable to alopecia Methods : We searched for the causes of alopecia in the bibliographic data from 41 sources of literature and the acupunctural treatments for alopecia in the bibliographic data from 49 sources of Chinese and Korean literature and from the journals of the acupunctural treatments for alopecia which have been published since 2000. Results : 1. The main causes of alopecia are blood deficiency, blood heat, static blood, depletion of kidney's water, wind excess, seven emotional damage, dietary damage, etc. 2. The acupuncture points frequently used are $GV_{20}$, $GB_{20}$, $ST_{36}$, $SP_6$, $SP_{10}$, $BL_{17}$, $BL_{18}$, $BL_{23}$, $GV_{23}$, $GV_{14}$, $CV_6$, $ST_8$, $KI_3$, $LR_3$, $HT_7$, $LI_{11}$, EX-$HN_1$, and ouch point. 3. New acupuncture therapies, including herbal acupuncture therapy, ear acupuncture therapy, dermal needle therapy, needle-embedding therapy and scalp acupuncture therapy are frequently used to treat alopecia. Conclusions : The acupuncture points frequently used for treating alopecia have characteristics such as tonifying blood, tonifying the liver and kidney, extinguishing wind, activating blood, clearing heat and draining dampness, so they are highly associated with the causes and the mechanisms of alopecia.

Cold Feet and Sleep Quality : An Exploratory Study Using Polysomnography and Pittsburgh Sleep Quality Index (족냉과 수면의 질 : 수면다원검사와 피츠버그 수면의 질 지수를 이용한 탐색적 연구)

  • Kwang-Ho Bae;Ki-Hyun Park;Il-Koo Ahn;Su-Eun Lim;Siwoo Lee
    • Journal of Society of Preventive Korean Medicine
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    • v.28 no.1
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    • pp.109-118
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    • 2024
  • Objectives : This study aimed to investigate the relationship between cold feet and sleep quality using polysomnography (PSG) and Pittsburgh Sleep Quality Index (PSQI). Methods : We divided 11 adults (6 females, 5 males) with Insomnia Severity Index score below 21 into cold feet (CF) and a non-cold feet (NCF) group based on the median feet temperature (Taichong, LR3). PSG and PSQI were administered to assess sleep characteristics and subjective sleep quality. Results : CF group exhibited significantly lower time in bed, sleep period time, and total sleep time compared to NCF group. While there were no significant group differences in sleep latency, wakefulness after sleep onset, or total arousal index, NCF group had significantly lower minimum oxygen saturation and apnea-hypopnea index in REM (rapid eye movement) sleep compared to CF group. Although the PSQI score and the proportion of poor sleepers were both higher in the CF group (7.40 and 80%) compared to the NCF group (5.50 and 50%), these differences did not reach statistical significance. Conclusions : This study showed that foot temperature affects sleep characteristics and suggests the need to utilize PSG in sleep research in Korean medicine.

Analysis of inter-fraction and intra-fraction errors during volumetric modulated arc therapy in Pancreas Ca (호흡 동조 췌장 암 용적 세기조절 회전 치료 시 Inter-fraction Intra-fraction 분석)

  • Jo, Young Pil;Seo, Dong Rin;Hong, Taek Kyun;Kang, Tae Yeong;Beck, Geum Mun;Hong, Dong Ki;Yun, In Ha;Kim, Jin San
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.247-256
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    • 2014
  • Purpose : To assess target motion during radiotherapy by quantifying daily setup errors and inter-fractional and intra-fractional movements of pancreatic fiducials. Materials and Methods : Eleven patients were treated via stereotactic body radiotherapy (SBRT) with volumetric modulated arc therapy. Bony setup errors were calculated using cone beam computed tomography (CBCT). Inter-fractional and intrafractional fiducial (seed) motion was determined via cone beam computed tomography (CBCT) projections and orthogonal fluoroscopy. Results : Using an off-line correction protocol, setup errors were 0.0 (-1.7-4.0), 0.3 (-0.5-3.0), and 0.0 (-4.1-6.6) mm for the left-right, anterior-posterior, and superior-inferior directions respectively. Random inter-fractional setup errors in the mean fiducial positions were -0.1, -1.1, and -2.3 mm respectively. Intra-fractional fiducial margins were 9.9, 7.8, and 12.5 mm, respectively. Conclusion : Online inter-fractional and intra-fractional corrections based on daily kV images and CBCT expedites SBRT of pancreatic cancer. Importantly, inter-fractional and intra-fractional motion needs to be measured regularly during treatment of pancreatic cancer to account for variations in patient respiration.

Common Peroneal Neuropathy Treated with Acupuncture plus Electro-acupuncture: Case Report (총비골신경병증 환자에 대한 침 및 침전기 자극술 병용 치험 1례)

  • Lee, Sang Young;Shin, Hyun Kwon;Kim, Ki Yuk;Hwang, Choon Ho;Jung, Pil Sun;Kim, Hee Young;Go, Yong Jun;Jo, Hyun Jung;Park, Jae Suk;Sul, Jae Uk;Jo, Hee Guen
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.5
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    • pp.672-676
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    • 2013
  • The purpose of this study is to report that a patient suffered from Common Peroneal Neuropathy (CPN) caused by ankle sprain was improved by acupuncture plus electro-acupuncture. In this study, the patient was diagnosed with magnetic resonance image(MRI) and electomyography(EMG). We treated at acupoints ST36, ST41, SP9, GB34, GB39 and LR3 by acupuncture plus electro-acupuncture twice a day for 16 days; a total of 30 times. We used evaluation scale including muscle manual testing(MMT) and visual analogue scale (VAS). MMT changed from Grade 0 to Grade 5 and VAS changed from 10 to 2 after treatment for 16days with hospitalization. Though it is a case report, these results suggest that acupuncture and electrical acupuncture might have valid effect on CPN in controlled environment.

Traditional Korean Medicine Treatment of a Traumatic Brain Injury Patient with Aggressive Behavior (외상성 뇌손상 환자의 공격성에 대한 치료 1례)

  • Park, Hye-lim;Hong, Min-na;Cho, Jae-hyun;Bae, Go-eun;Choi, Jin-yong;Hong, Jin-woo;Park, Seong-ha;Lee, In
    • The Journal of Internal Korean Medicine
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    • v.37 no.5
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    • pp.831-838
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    • 2016
  • Objective: To describe the effectiveness of traditional Korean medicine (TKM) on a patient showing aggressive behavior after a traumatic brain injury. Methods: We used complex TKM treatments. The acupoints used were as follows: Soyangin Taegeuk acupuncture (HT3, KI3, and SP3) and acupoints frequently used in hemiparesis (GV20, GV24, ST4, LI11, LI4, ST36, GB34, SP9, and LR3). Moxibustion was also applied to GV20, and herbal medicine (Samulanshin-tang-gami, 四物安神湯 加味方) was administered. The efficacy was evaluated at baseline, week 8, and week 16 using the Modified Overt Aggression Scale (MOAS). Results: After 8 weeks, the total MOAS score was decreased from 13 to 5, and this score was maintained until week 16. The average sleep time was increased and waking up during the night was decreased. Conclusions: We suggest that TKM could be effective for reducing aggressive behavior and alleviating sleep disturbances. Further studies are needed.

A Study on the Letter about Gaining Child of 『Beijiqianjinyaofang』 and 『Qianjinyifang』 (『비급천금요방(備急千金要方)』 및 『천금익방(千金翼方)』의 구자문(求子門)에 대한 연구(硏究))

  • Park, Cheol-hong;Lyu, Jeong-ah
    • Journal of Korean Medical classics
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    • v.31 no.3
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    • pp.59-75
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    • 2018
  • Objectives : Contents regarding Qiuzimen as found in Beijiqianjinyaofang and Qianjinyifang were studied for their potentialities to be applied to infertility clinics. Methods : The contents on Qiuzimen in Beijiqianjinyaofang and Qianjinyifang are pondered upon after dividing into two categories of medical theory and therapeutic principle, and other related texts and dissertations are further studied to discover a potential subject matter in being applied to today's modern clinics. Results : 1. In medical theory, Sunsimiao picked five overexertions and seven damages as the main medical cause of infertility. For remedy, he established four common formula, which are: chinjasan, bakchotangpotang, suppository, and haseog(cheon)moondongwhan. 2. There are total of thirteen types of formula described in the Qiuzimen in Beijiqianjinyaofang and Qianjinyifang, and five acupuncture points are used in the moxibustion method. After analyzing the herbs that were used six or more times, it was discovered that medicines were used to tonify the viscera of heart and kidney that are damaged through five overexertions and seven damages. In moxibustion method, different points such as CV4, LR14, pomoon, cheonmoon, and KI2, which is the point for kidney meridian were used in order to tonify the uterus through lower abdomen area and reproductive organs. 3. Qiuzimen has not only had a great impact on the infertility treatment as found in Furendaquanliangfang, which is the first gynecology text in Song dynasty, but it also had a continuous impact on medical texts in Ming and Qing dynasty. 4. The infertility therapeutic principle and approach method as found in the Qiuzimen are still relevant in today's modern infetility treatment. Conclusions : In the Qiuzimen of Beijiqianjinyaofang and Qianjinyifang, the problem of infertility is viewed as the whole body's problem, namely a type of defective disease caused by five overexertions and seven damages, the view of which should be applied to today's modern clinics.

Effects of Acupuncture and Moxibustion at SP6(Sanyinjiao) on the Temperature Change of Feet in Healthy Adults (삼음교(三陰交)(SP6) 침구자극(鍼灸刺戟)이 정상 성인의 족부(足部) 온도 변화에 미치는 영향)

  • Kim, June Hyun;Choi, Han Gyul;Park, Min Cheol;Jo, Eun Heui
    • Journal of Acupuncture Research
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    • v.33 no.3
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    • pp.75-87
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    • 2016
  • Objectives : The purpose of this study is to investigate the effects of acupuncture and moxibustion treatment at SP6(Sanyinjiao) on the temperature change of feet in healthy adults and evaluate whether SP6 has an effect on cold hypersensitivity of feet. Methods : Subjects of this study were 61 healthy adults consisting of 21 in the acupuncture treatment group, 21 in the moxibustion treatment group and 19 in the control group, selected at random. After starting the experiment, the subjects laid straight on their back and relaxed for 30 minutes. Pictures were then taken of their feet by DITI 3 times before and after treatment. The treatment was carried out by either 15 minutes of acupuncture or 2 pieces of moxibustion at SP6. Whilst the control group rested lying straight. After taking pictures the temperatures of LR2, GB42, ST42, KI1, center of the plantar, and center of the calcaneus were checked and the SPSS for Windows Version 20.0 was used to evaluate the statistical significance by the paired t-test, Wilcoxon signed-ranks test(in group) and the Mann-Whitney U-test(between the groups). Results : Some temperature changes before and after treatment were observed in each of the 12 areas, most of which were not significant. But as a result of comparing the temperature difference of all the samples without dividing the area of each group, the mean temperatures in the acupuncture and moxibustion group were significantly elevated. A comparison between the groups showed the mean temperature of the acupuncture and moxibustion group to be significantly elevated, more so than the control group. Conclusion : The result of this study suggests acupuncture and moxibustion treatment at SP6 has the effect of the rising temperature of feet temporarily.

Suboptimal Decision Fusion in Wireless Sensor Networks under Non-Gaussian Noise Channels (비가우시안 잡음 채널을 갖는 무선 센서 네트워크의 준 최적화 결정 융합에 관한 연구)

  • Park, Jin-Tae;Koo, In-Soo;Kim, Ki-Seon
    • Journal of Internet Computing and Services
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    • v.8 no.4
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    • pp.1-9
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    • 2007
  • Decision fusion in wireless sensor networks under non-Gaussian noise channels is studied. To consider the tail behavior noise distributions, we use a exponentially-tailed distribution as a wide class of noise distributions. Based on a canonical parallel fusion model with fading and noise channels, the likelihood ratio(LR) based fusion rule is considered as an optimal fusion rule under Neyman-Pearson criterion. With both high and low signal-to-noise ratio (SNR) approximation to the optimal rule, we obtain several suboptimal fusion rules. and we propose a simple fusion rule that provides robust detection performance with a minimum prior information, Performance evaluation for several fusion rules is peformed through simulation. Simulation results show the robustness of the Proposed simple fusion rule.

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