• Journal of Korean Neurosurgical Society
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• 제46권1호
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• pp.11-15
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• 2009

Objective: Two findings easily found at coronal source images of MR myelography (MRM) were evaluated : dorsal root ganglion (DRG) swelling and running course abnormality (RCA) of L5 exiting root at foramen or extraforamen. We tried to find the sensitivity of each finding when root was compressed. Methods: From 2004 July to 2006, one hundred and ten patients underwent one side paraspinal decompression for their L5 root foraminal or extraforaminal compression at L5-S1 level. All kinds of conservative treatments failed to improve leg symptom for several months. Before surgery, MRI, CT and MRM were done. Retrospective radiologic analysis for their preoperative MRM coronal source images was done to specify root compression sites and L5 root morphologic changes. Results: DRG swelling was found in 66 (60%) of 110 patients. DRG swelling has statistically valuable meaning in foraminal root compression (chi-square test, p<0.0001). Seventy-two (66%) in 110 patients showed abnormal alteration of running course. Abnormal running course has statistically valuable meaning in foraminal or extraforaminal root compression (chi-square test, p<0.0001). Conclusion: Three-dimensional MRM provides precise thin sliced coronal images which are most close to real operative views. DRG swelling and running course abnormality of L5 exiting root are two useful findings in diagnosing L5 root compression at L5-S1 foramen or extraforamen. MRM is thought to provide additional diagnostic accuracy expecially in L5-S1 foraminal and extraforaminal area.

• Journal of Ginseng Research
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• 제5권1호
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• pp.35-40
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• 1981

Explants of mature root tissues and calli derived from root and cotyledon of Panax ginseng were cultured in vitro on Murashige and Skoog medium supplemented with 2, 4-dichlorophen-oxyacetic acid(3,4-D), naphthaleneacetic acid(NAA), benzyladenine, and gibberellic acid to assess their capacity to regenerate organs. Root formation at high percentage (46.2-61.1%) was obtained 20-30 days after culturing on media supplemented with combinations of NAA(5 mg/l) and kinetin (1 mg/l), And calli derived from cotyledon produced numerous embryoids in media($\frac{1}{2}$MS) containing 2,4-D(0.5 mg/l) and kinetin (0.5 mg/l). Reculture of these embryoids in media($\frac{1}{2}$MS) enriched with 1 mg/l of benzyladenine and 1 mg/l of gibberellic acid resulted in more plantlet regeneration.

• The Korean Journal of Pain
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• 제11권2호
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• pp.307-310
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• 1998

Selective lumbosacral radiculography and nerve root block techniques are very useful in determining the nerve root involved. We have done the lumbar root block to 61-year-old female who had suffered from low back pain radiating to right lower leg which was not relieved by epidural steroid injection two times. $L_5$ root block was performed under the fluoroscopic C-arm guide. When the needle was in correct position, we injected contrast medium (Isovist$^{(R)}$ - 300, Schering, Germany). After we injected 1.5 cc isovist, the S1 root was figured but L5 root was not figured. When we reinjected 1.5 cc isovist, $S_1$ root was enhanced and $L_5$ root was slightly visible due to severe disc bulging and lateral spinal stenosis.

• 대한본초학회지
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• 제21권1호
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• pp.79-87
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• 2006

Objectives : Effects of Rhodiola rosea root on cancers on stomach, breast, lung, and liver were examined. Methods : Water extracts and methanol extracts of Rhodiola rosea root were treated on cancer cells, and its effects on cancers were examined. Results : 1. Water extracts and methanol extracts of Rhodiola rosea root was less harmful in its lowest density 0.25 mg/mL (9.l%와 10.5%), but became more harmful as its density increased. 2. As for human stomach adenocarcinoma cells AGS, breast adenocarcinoma cells MCF-7, and lung carcinoma cells A549, methanol extracts showed 70-77% inhibition of cancer cells in high density(1 mg/mL), and water extracts showed 60-70% inhibition rate and its selective death rate was less than 2.5. Conclusion : Rhodiola rosea root can be used to treat cancers and to increase immunity.

• 대한소아치과학회지
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• 제39권4호
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• pp.366-372
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• 2012

본 연구의 목적은 현재 많이 사용되고 있는 ProRoot MTA (Dentsply Tulsa, USA)와 최근 국내에서 새로 개발된 OrthoMTA (Bio MTA, Korea)의 감염된 근관에서 주로 발견되는 3개의 미생물에 대한 효과를 다양한 농도와 시간에서 비교하는 것이다. 50, 25, 12.5 mg/mL의 농도로 준비된 ProRoot MTA와 OrthoMTA에 Enterococcus faecalis, Fusobacterium nucleatum 그리고 Staphylococcus epidermidis를 접종 후 24, 48, 72시간에 항미생물 효과를 관찰하여 다음과 같은 연구결과를 얻었다. E. faecalis의 경우 ProRoot MTA와 OrthoMTA 50, 25, 12.5 mg/mL 농도의 모든 시간대에서 세균을 완전히 억제하지는 못했지만 양성 대조군에 비해 성장이 조금 감소한 양상을 보였다(p < 0.05). F. nucleatum의 경우 ProRoot MTA 50 mg/mL 농도의 24시간에서 미생물을 억제하였으나 시간이 지남에 따라 세균의 성장을 보인 반면 OrthoMTA의 경우 같은 농도에서 시간이 지나도 계속 세균을 억제하였다(p < 0.05). S. epidermidis의 경우 ProRoot MTA 50 mg/mL, OrthoMTA 50, 25 mg/mL 농도의 24시간에서 억제 효과를 보였으나 시간이 지나면서 세균이 조금씩 성장하였다. 그러나 전체적으로 모든 농도와 시간에서 양성 대조군에 비해서는 억제 효과를 나타냈다(p < 0.05). 본 연구를 통해 국내에서 새로 개발된 OrthoMTA는 기존의 ProRoot MTA보다 항균활성을 가지고 있음을 알 수 있었다.

• 식품보건융합연구
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• 제5권1호
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• pp.13-19
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• 2019

Proximate analysis of Ipomea batatass L. grown in two different locations in Imo State were investigated. Standard soil analytical method was used to determine the physiochemical contents of the two soil sample collected from Mgbidi and Orji Ipomea batatass L. farm land. The soil sand from Ipomea batatass L. root in Orji farm recorded highest percentage value of 75.00% compared to the soil sand Ipomea batatass L. root in Mgbidi farm with 27.00% value. The percentage value of silt was different as the soil Ipomea batatass L. root in Mgbidi farm had high value of 29.40% while soil silt of Ipomea batatass L. root in Orji farm had 13.40%. The soil clay, pH, Phosphorus and Nitrogen from Ipomea batatass L. root in Mgbidi farm recorded highest percentage value of 43.60%, 5.7, 23.20 and 0.35 compared to the soil sand Ipomea root in Orji farm with 11.60%, 5.4, 16.70 and 0.09 value respectively. Ca, Mg, K, and Na analyzed followed the same trend as the soil from Ipomea root in Mgbidi farm had high percentage value of Ca (10.00), Mg (1.60), K (0.54) and Na (0.43) respectively. The systematic study of physiochemical of the Ipomea soils could help in understanding the nutritional composition, the basic characteristics of the soils and the constraints associated with the management of the soils from the two locations.

• 한국식품영양학회지
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• 제6권2호
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• pp.109-114
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• 1993

This study was divised to observe an Inhibitory effect toward a lipolytic action of toxohormone-L from large root and small root Nepal pseudo ginseng (NPG ; Nepal products) components by water extract and ethanol precipitate in vitro. Toxohormone-L is known to be a lipolytic factor that was partially purified from the ascites fluid of Sarcoma 180-bearing mice and of patients with hepatoma. The inhibitory effect that inhibited the lipolytic action of toxohormone-L by ethanol Precipitate component of large root NPG (mean 55.5%) was higher (mean 1.37 times) than that of water extract component in final reaction concentration of 500 and 1, 000ug/ml, on the other side inhibitory effect of water extract component in small root NPG (mean 55.5%) was higer (mean 1.14 times) than that of ethanol precipitate component. In a way inhibitory effect of precipitate component In large root NPG(47.6%), when final reaction concentration of sample were 1, 000ug/ml, was about 40% lower than that of Korean red ginseng.

• Journal of Plant Biotechnology
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• 제49권3호
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• pp.207-212
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• 2022

작약 뿌리 절편으로부터 유도된 캘러스 클론으로부터 부정근 발생에 대한 최적의 배양조건을 조사하기 위하여 뿌리 절편으로부터 캘러스 유도를 위해서 먼저 0.5, 1.0, 2.0, 3.0, 4.0 mg/L 농도의 오옥신(IAA, NAA, IBA, 2,4-D)과 0, 0.5, 1.0, 2.0 mg/L 농도의 싸이토카닌(kinetin, zeatin, BAP)를 조합한 MS 배지에서 배양하였다. 캘러스 클론으로부터 부정근 유도와 길이 생장은 0.1, 0.5, 1.0 mg/L 농도의 오옥신(IAA, NAA, IBA) 또는 싸이토카닌(kinetin, zeatin, BAP)을 단독으로 첨가한 배지에서 암 조건으로 그리고 0.1, 0.5, 1.0 mg/L 농도의 IBA와 zeatin을 각각 조합 첨가한 배지에서 명/암 조건으로 6주 동안 배양하였다. 캘러스 형성은 다른 조합 처리보다 1.0 mg/L 농도의 NAA와 zeatin을 조합 첨가한 배지에서 가장 효과적이었으며, 캘러스 클론으로부터 부정근 발생 수와 부정근의 길이 생장은 IBA 단독처리의 경우 각각 6.66개와 4.82 cm, zeatin 단독 처리의 경우 2.32개와 0.92 cm로 다른 호르몬에 비해 우수하였다. 특히 0.1 mg/L IBA와 0.5 mg/L zeatin을 조합 첨가한 배지에서 광 조건으로 배양할 경우 가장 많은 부정근이(14.06) 형성되었으며, 동일배지에서 암 조건으로 배양할 경우 부정근의 길이가 가장 긴 5.45 cm로 측정되어 가장 효과적인 농도와 조합임을 알 수 있었다. 이러한 작약의 기내 배양에 대한 최적의 배양 조건은 기내배양을 통해 작약 부정근의 대량 생산을 위한 배지로 사용할 수 있음을 보여 주었다.

• The Korean Journal of Pain
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• 제13권2호
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• pp.247-250
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• 2000

Recently, some authors reported that discogenic low back pain should be regarded as a referred pain in respect of neural pathway. The afferent pathways of discogenic low back pain is transmitted mainly by sympathetic afferent fibres from the sinuvertebral nerves in the second lumbar nerve root. This pain arises from the lumbar intervertebral discs, and it had been transmitted mainly through the sympathetic afferent fibres contained in the second lumbar spinal nerve root. Second lumbar dermatome corresponds to the low back area. We experienced a case of low back pain which could not be controlled by conventional therapy and progressed wax and wane. The CT finding showed bulging disc between $L_4$ and $L_5$ and spinal stenosis in $L_4$ area. And epiduroscopic feature showed severe adhesion in $L_4$, $L_5$ and $S_1$. After we blocked $L_2$ root, pain score decreased 10 to 2. Therefore, the $L_2$ root block may be a useful diagnostic procedure as well as provide therapeutic value.

• Journal of Ginseng Research
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• 제25권3호
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• pp.130-135
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• 2001

식물조직배양기술을 이용하여 사포닌 함량이 높은 인삼 root를 생산하고자, 인삼 root의 생장과 사포닌생산에 미치는 배지와 식물생장조절물질의 영향을 조사하였다. 인삼 root를 여러 종류의 배지에 배양하였을 때, 인삼 root의 생장과 사포닌 생산은 SH배지에서 가장 우수하였고, SH배지에 배양시, 접종후 약 10일후에 생체중량이 초기접종량의 2배가 되었다. 각 배지별로 배양한 인삼 root의 진세노사이드 패턴과 함량은 다소 차이가 있었는데, SH배지와 White배지에서 성장한 인삼 root의 총진세노사이드 함량이 가장 높았다. 생장조절물질에 있어서는 4.0mg/L NAA를 함유한 SH배지에서 성장한 인삼 root의 생장이 가장 우수하였고, 사포닌 함량은 0.5mg/L BAP 처리구에서 가장 높았다. 이러한 결과들은 인삼 root 배양에 의해 사포닌을 단기간에 생산할 수 있는 가능성을 제시하고 있다.