• Title/Summary/Keyword: L-77

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Change in Plasma Vascular Endothelial Growth Factor after Gamma Knife Radiosurgery for Meningioma : A Preliminary Study

  • Park, Seong-Hyun;Hwang, Jeong-Hyun;Hwang, Sung-Kyoo
    • Journal of Korean Neurosurgical Society
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    • v.57 no.2
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    • pp.77-81
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    • 2015
  • Objective : The purpose of this study was to investigate changes in the plasma level of vascular endothelial growth factor (VEGF) after Gamma Knife radiosurgery (GKRS) for the treatment of meningioma. Methods : Fourteen patients with meningiomas had peripheral venous blood collected at the time of GKRS and at 1 week, 1 month, 3 month and 6 month visits. Plasma VEGF levels were measured using commercially available enzyme-linked immunosorbent assay. For controls, peripheral blood samples were obtained from 20 healthy volunteers. Results : The mean plasma VEGF level (29.6 pg/mL) in patients with meningiomas before GKRS was significantly lower than that of the control group (62.4 pg/mL, p=0.019). At 1 week after GKRS, the mean plasma VEGF levels decreased to 23.4 pg/mL, and dropped to 13.9 pg/mL at 1 month, 14.8 pg/mL at 3 months, then increased to 27.7 pg/mL at 6 months. Two patients (14.3%) with peritumoral edema (PTE) showed a level of VEGF 6 months after GKRS higher than their preradiosurgical level. There was no significant association found in an analysis of correlation between PTE and tumor size, marginal dose, age, and sex. Conclusion : Our study is first in demonstrating changes of plasma VEGF after stereotactic radiosurgery (SRS) for meningioma. This study may provide a stimulus for more work related to whether measurement of plasma level has a correlation with tumor response after SRS for meningioma.

Screening for Herbicidal Medicinal Plants against Digitaria Sanguinalis and Taraxacum Platycarpum in Turf (잔디밭 잡초 바랭이와 민들레 방제를 위한 살초활성 약용식물의 탐색)

  • Kim, Dae-Ho;Kang, Jae-Young;Kim, In-Seob;Jeon, Min-Goo;Lee, Jae-Deuk;Kim, Ik-Hwi
    • Asian Journal of Turfgrass Science
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    • v.26 no.1
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    • pp.60-66
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    • 2012
  • Crabgrass (Digitaria sanguinalis L.), Dandelion (Taraxacum platycarpum H. DAHLST.), Annual bluegrass (Poa annua L.), Gree kyllinga (Kyllinga brevifolia var.), Red clover (Trifolium pratense L.), Annual lespedeza (Kummerowia striata (Thunb.)Schindl.), Mugwort (Artemisia capillaris Thunb.), Horseweed (Erigeron canadensis L.), Field horsetail (Equisetum arvense L.) are major weeds in turf. In this study, 23 medicinal plant extracts were tested for herbicidal activities against crabgrass and dandelion in the course of major weed in turf. In pot experiment, we implemented pre-emergence application used medicinal plant extracts showed herbicidal activity in petridish experiment. In effect, inhibition rates of germination were 61.0% at Curcuma longa extract and 62.5% at Cnidium officinale extract in crabgrass pot experiment, and 77.8% at Ailanthus altissima extract in dandelion pot experiment.

Conversion of Red-macroalgae Eucheuma spinosum to Platform Chemicals Under Ferric Chloride-catalyzed Hydrothermal Reaction (Ferric chloride를 이용한 Eucheuma spinosum으로부터 플렛폼 케미컬의 생산)

  • Jeong, Gwi-Taek;Kim, Sung-Koo
    • Korean Chemical Engineering Research
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    • v.58 no.2
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    • pp.293-300
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    • 2020
  • Eucheuma spinosum, red macro-algae, contains carrageenan as the major polysaccharide and is commercially produced in Indonesia, Malaysia, Philippines, China and Tanzania. In this study, E. spinosum was converted to sugar and platform chemicals (5-HMF, levulinic acid, formic acid) via FeCl3-catalytic hydrothermal reaction. In addition, statistical methodology (3-level 3-factor Box-Behnken design) was applied to optimize and evaluate the effects of reaction factors (reaction temperature, catalyst concentration and reaction time). As a result of optimization, the concentration of 5-HMF was obtained to be 2.96 g/L at 160 ℃, 0.4 M FeCl3 and 10 min. Optimal conditions of levulinic and formic acids were determined at 200 ℃, 0.6 M FeCl3 and 30 min, and the concentrations were obtained to be 4.26 g/L and 3.77 g/L, respectively.

DEVELOPMENT OF A S/W SYSTEM FOR RELATIVE POSITIONING USING GPS CARRIER PHASE (GPS의 반송파 위상을 이용한 상대측지 S/W의 개발)

  • 안용원;김천휘;박필호;박종옥;조정호
    • Journal of Astronomy and Space Sciences
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    • v.14 no.2
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    • pp.347-354
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    • 1997
  • We developed a GPS phase data processing S/W system which calculates baseline vectors and distances between two points located in the surface of the Earth. For this development a Double-Difference mothod and L1 carrier phase data from GPS(Global positioning System) were used. This S/W system consists of four main parts: satellite position calculation, Single-Difference equation, Double-Difference equation, and correlation. To verify our S/W, we fixed KAO($N36^{circ}.37,E127^{circ}.37,H77.61m$), one of the International GPS Services for Geodynamics, which is located at Tae-Jon, and we measured baseline vectors and relative distances with data from observations at approximate baseline distances of 2.7, 42.1, 81.1, 146.6km. Then we compared the vectors and distances with the data which we obtained from the GPSurvey S/W system, with the L1/L2 ION-Free method and broadcast ephemeris. From the comparison of the vectors and distances with the data from the GPSurvey S/W system, we found baseline vectors X, Y, Z and baseline distances matched well within the extent of 50cm and 10cm, respectively.

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Study on the Behavior of the Fish - 1 . The Swimming Force of Crusian Carp , Carassius Carassius - (어류의 행동에 관한 연구 - 1 . 붕어의 유영력 -)

  • 손태준
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.20 no.1
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    • pp.1-5
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    • 1984
  • The author carried out an experiment for the dynamical swimming force of crusian carp, Carassius carassius. The experimental water tank was made of 4mm thick transparent acryl board in the right hexahedral shape (400L$\times$240W$\times$800H mm). The water temperature in the tank ranged 20.6$^{\circ}C$ to 21.2$^{\circ}C$. The water level in the tank was maintained 70cm high from the bottom. The measurement of the swimming force was carried out by use of strain gauge. The results obtained can be summarized as follows: 1) The momentary maximum swimming force F sub(M) (g) and the sustainable maximum swimming force F sub(s) (g) can be expressed as a function of the body weight W(g). F sub(M) =1.45W, F sub(s) =0.29W where the momentary maximum swimming force means the highest value, and the sustainable maximum swimming force means the mean high value sustained for 4 to 5 seconds presented in the recording paper. 2) F sub(M) and F sub(s) can be expressed as a function of the body length L(cm). F sub(M) =0.11L super(2.63), F sub(s) =0.15L super(1.77) 3) The coefficient of hydraulic resistance for crusian carp was derived as 0.287.

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Quality Characteristics of Sugar-snap Cookies by additions of Curcuma Longa L. Powder (강황분말을 첨가한 Sugar-snap cookies의 품질 특성)

  • Choi, Young-Sim;Lee, Myung-Ho;Jhee, Ok-Hwa
    • Culinary science and hospitality research
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    • v.17 no.2
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    • pp.198-208
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    • 2011
  • The purpose of this study is to investigate the quality characteristics of sugar-snap cookies prepared with Curcuma Longa L. powder(0, 3, 6, 9, 12, 15%) substituted for flour. The pH of the dough of sugar-snap cookies ranged from 6.58 to 7.32, and their moisture contents ranged from 9.09% to 10.77%. The width and spread factor of sugar-snap cookies decreased significantly with increase in Curcuma Longa L powder content(p<0.05); Lightness decreased significantly as the Curcuma Longa L. powder content increased while redness and yellowness increased significantly(p<0.05). Hardness increased with more powder added, and sensory evaluation indicated that the samples with 6% of the powder received higher scores in terms of taste, color, flavor, texture and overall tastes. As a result, sugar-snap cookies with 6% of Curcuma Longa L. powder were valued as best.

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Population Pharmacokinetics for Gentamicin in American and Korean-American Appendicitis Patients Using Nonparametric Expected Maximum(NPEM) Algorithm (비모수적 기대최대치(NPEM)연산방법에 의한 미국인과 재미동포 충수돌기염 환자에게 겐타마이신의 모집단 약물동태학)

  • ;;Stanford Jhee;Gill, Mark A.
    • YAKHAK HOEJI
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    • v.39 no.2
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    • pp.103-112
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    • 1995
  • Population pharmacokinetics for gentamicin were compared with 24 American patients (16 male and 8 female) and 16 Korean-American appendicitis patients(12 male and 4 female). Two to six blood specimens were collected from all patients at the following times: just before a regularly scheduled infusion and at 1/2 hour after the end of a 1/2 hour infusion. Nonparametric expected maximum(NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant(K), the slope of the relationship between K versus creatinine clearance(KS), the apparent volume of distribution(V), the slope of the relationship between V versus weight(VS), gentamicin clearance(CL) and the slope of the relationship between CL versus creatinine clearance and the VS(CS). The output includes a 3-dimensional plot of the joint probability density function(PDF), two marginal PDF, means, medians, modes, variance, skewness, kurtosis, and CV%. The mean K(KS) were 0.424$\pm$0.139(0.00429$\pm$0.00164) and 0.411$\pm$0.135 hr$^{-1}$ (0.00475$\pm$0.00180[hr.mL/min/1.73m$^{2}]^{-1}$) for American and Korean-American populations, respectively. The mean V(VS) were not different at 15.6$\pm$4.77(0.233$\pm$0.0526) and 15.1$\pm$3.84L(0.239$\pm$0.0492 L/kg) for American and Korean-American populations, respectively (P>0.2). The mean CL (CS) were 6.28$\pm$1.85(0.0634$\pm$0.0191) and 5.70$\pm$1.77 L/hr(0.0701$\pm$0.0215 L/kg[hr.mL/min/1.73m$^{2}$)] for American and Korean-American populations, respectively. There are no differences in gentamicin pharmacokinetics between American and Korean-American Appendicitis patients.

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A Study on a Binary Random Sequence Generator with Two Characteristic Polynomials (두개의 특성 다항식으로 구성된 이진 난수열 발생기에 관한 연구)

  • 김대엽;주학수;임종인
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.12 no.3
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    • pp.77-85
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    • 2002
  • A Research of binary random sequence generator that uses a linear shift register had been studied since the 1970s. These generators were used in stream cipher. In general, the binary random sequence generator consists of linear shift registers that generate sequences of maximum period and a nonlinear filter function or a nonlinear combination function to generate a sequence of high linear complexity. Therefore, To generate a sequence that have long period as well as high linear complexity becomes an important factor to estimate safety of stream cipher. Usually, the maximum period of the sequence generated by a linear feedback shift register with L resistors is less than or equal to $2^L$-1. In this paper, we propose new binary random sequence generator that consist of L registers and 2 sub-characteristic polynomials. According to an initial state vector, the least period of the sequence generated by the proposed generator is equal to or ions than it of the sequence created by the general linear feedback shift register, and its linear complexity is increased too.

Treatment Characteristics Using Full-Scale SBR System (Full-Scale SBR 공법을 이용한 처리특성)

  • Choo, Tai-Ho;Lee, Yong-Doo;Cho, Yong-Hyun
    • The Journal of the Korea Contents Association
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    • v.6 no.10
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    • pp.34-40
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    • 2006
  • In this study, the treatment of organic matters and nutrients like Nitrogen and Phosphorus with sequencing batch reactors (SBR) was conducted. The following conclusions can be summarized from the study. The influent BOD concentration was varied 19.6 to 40.0mg/L and the effluent was 3.0 to 14.8mg/L. The variations of BOD removal efficiency during the experimental period was $47.9{\sim}88.4%$ and the average was 80.8%. The average removal efficiency was stabilized with the passage of time. Also the COD concentration was flowed into as $12.2{\sim}32.0mg/L$ and the effluent concentration was varied 3.3 to 18.6 mg/L, and then the average COD removal efficiency was 57.3%(minimun 19.2% and maximum 78.6%). But fortunately, the COD removal efficiency was also stabilized as 70.2% after 79days. In the case of T-N, the influent concentration range was $7.53{\sim}14.99mg/L$ and the effluent concentration was 6.59mg/L(the average removal efficiency was 40.3%) until the first experiment time 79days. But after normalizing the system, it was 4.44mg/L (the average removal efficiency was 56.4%). Also the influent T-P concentration was varied from 0.77 to 1.91mg/L and the effluent concentration was $0.26{\sim}1.53mg/L$. The removal efficiency was varied from 5.3 to 71.7%. considerably, therefore the average removal efficiency was 42.6%. The reason was concluded that the sludge wasn't discharged for increasing MLSS concentration.

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Biogas Production from Sewage Sludge in 30L Microbial Electrolysis Cell (30L 미생물전기분해전지의 하수슬러지로부터 바이오가스 생산 특성)

  • Lee, Myoung-Eun;Ahn, Yongtae;Shin, Seung Gu;Seo, Sun-Chul;Chung, Jae Woo
    • Journal of the Korea Organic Resources Recycling Association
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    • v.27 no.4
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    • pp.25-33
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    • 2019
  • Operating characteristics of a 30 L microbial electrolysis cell (MEC) for producing biogas from sewage sludge was studied. During the 32-day inoculation period, carbon dioxide concentration decreased and methane concentration increased with operating time, and the overall methane content of biogas was 69.1% with a production rate of 171.6 mL CH4/L·d. In fed-batch experiments for 6 operating cycles, CH4 concentration of 66.5~77.2% was obtained at a production rate of 184.9~372.9 mL CH4/L·d, COD, TS and VS removal efficiency ranged from 28.2 to 42.1%, 20.7 to 37.5% and 18.5 to 36.9%, respectively. The MEC system was observed to be stabilized as operating cycles were repeated after inoculation. In the last operating cycle, 5221 mL/L of methane was produced with CH4 yield of 316.7 L CH4/kg CODrem, and the energy recovery was 73%.