• Korean Journal of Food Science and Technology
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• v.47 no.1
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• pp.95-102
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• 2015

The Maillard reaction is a non-enzymatic reaction between amino and carbonyl groups. During milk processing, lactose reacts with milk protein through this reaction. Infant formulas (IFs) are milk-based products processed with heat-treatments, including spray-drying and sterilization. Because IFs contain higher Maillard reaction products (MRPs) than breast milk, formula-fed infants are subject to higher MRP exposure than breast milk-fed ones. In this study, we investigated the optimization of conditions for minimal MRP formation with the addition of $\small{L}$-carnitine ($\small{L}$-car), pyridoxine hydrochloride (PH), and $\small{DL}$-${\alpha}$-tocopheryl acetate (${\alpha}$-T) in an IF model system. MRP formation was monitored by response surface methodology using fluorescence intensity (FI) and 5-hydroxymethylfurfural (HMF) content. The optimal condition for minimizing the formation of MRPs was with $2.3{\mu}M$ $\small{L}$-car, $15.8{\mu}M$ PH, and $20.6{\mu}M$ ${\alpha}$-T. Under this condition, the predicted values were 77.4% FI and 248.7 ppb HMF.

• Journal of the East Asian Society of Dietary Life
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• v.25 no.1
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• pp.183-192
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• 2015

This study aimed to produce fermented extracts with sugar made from lotus root (LR) and Platycodon grandiflorum (PG), using lactic acid fermentation, and confirmed their physiological and anti-oxidative activities as basic data for manufacturing functional drinks through sensory tests. For the final sugar concentrations, PG showed $48.1^{\circ}brix$ and LR showed $52.0^{\circ}brix$. Sugar concentrations during lactic acid fermentation following dilution of sugar to $12^{\circ}brix$, ranged from $11.5{\sim}12.1^{\circ}brix$ for PG and $11.9{\sim}12.4^{\circ}C$ for LR. During lactic acid fermentation, lactic acid bacteria numbers tended to decrease in both fermented LR and PG extracts with sugar as the fermentation period increased. For DPPH radical scavenging ability, LR was three times higher in control without lactic acid fermentation while PG showed significant increases in L. acidophilus (77%), L. brevis (90%), and L. delbrueckii (177%) during lactic acid fermentation. For total polyphenol content, LR showed a higher concentration than PG, and except for fermented L. delbrueckii extract showing similarity with the control, contents of fermented extracts decreased. In the case of PG, CUPRAC, increased significantly in L. brevis, whereas FRAP, increased significantly in L. delbrueckii with lactic acid fermentation. For reducing power, except for fermentation with L. brevis, all PG showed lower reducing power activities. In the sensory test of fermented LR and PG extracts with sugar, both fermented extracts showed better results with L. brevis or L. delbrueckii than control or those with L. acidophilus in every item. Based on these results, it is highly possible to develop fermented extract drinks with sugar using LR or PG. In particular, lactic acid bacteria such as L. delbrueckii and L. brevis showed generally higher activities with potential as a functional drink.

• Journal of the Korean Magnetic Resonance Society
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• v.6 no.1
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• pp.69-77
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• 2002

During the screening of material which has the antimicrobial activity against aminoglycoside-resistant bacteria, A new material $\varepsilon$-(L-$\beta$-Iysine) polypeptide from a culture medium of Streptomyces sp.(DWGS2) was isolated, and the structure and the physicochemical properties of the new material were elucidated. The new material was separated by column chromatography of the culture medium using Dowex1$\times$2, Silica gel, and Sephadex LH20 etc. The chemical structure and molecular weight were determined with the data of various NMR experiments, MALDI mass, and ESI mass experiments. The antimicrobial activity of $\varepsilon$-(L-$\beta$-Iysine) polypeptide is not only better than equal to the activity of known aminoglycoside type of antibiotics(MIC=3.125 - 6.25ug/mL) but also effective against aminoglycoside-resistant bacteria and fungi. If the mechanism of antimicrobial activity against aminoglycoside- resistant bacteria is figured out, the $\varepsilon$-(L-$\beta$-Iysine) polypeptide can be utilized for the treatment of diseases caused by aminoglycoside-resistant bacteria.

• Journal of the Korean Applied Science and Technology
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• v.29 no.2
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• pp.302-310
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• 2012

Bio assay of mercury and cadmium ions were searched using voltammetric analysis using DNA doped carbon nanotube paste electrodes (DCP). The square-wave stripping voltammetryic optimized results indicated working ranges of 1-10.0 $ngL^{-1}$ and 20-100 $ugL^{-1}$, Hg(II) Cd(II) within an accumulation time of 120 seconds, in 0.1-M phosphate buffer solutions of pH 6.3. The relative standard deviations of 5 $ngL^{-1}$ Hg(II) and Cd(II) that observed were 0.14 and 0.22% (n=12), respectively, using optimum conditions. The low detection limit (S/N) was pegged at 0.1 $ngL^{-1}$ ($4.9{\times}10^{-11}M$) Hg(II) and 0.2 $ngL^{-1}$ ($1.77{\times}10^{-10}M$) Cd(II). The developed methods can be applied to assays in biological fish kidneys and water samples.

• Journal of Environmental Science International
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• v.25 no.6
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• pp.829-837
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• 2016

The mechanism of micro-bubble generation with a pump is not clarified yet, so the design of water treatment systems with a micro-bubble generating pump is based on trial and error methods. This study tried to explain clearly quantitative relationships of experimental micro-bubble concentration ($C_{air}$) of continuous operation tests with a micro-bubble generating pump and theoretical air solubility. Operation parameters for the tests were discharge pressure ($P_g$), water ($Q_{w0}$) and air ($q_0$) flow rates, orifice diameter ($D_o$), and retention time (t). The experimental micro-bubble concentrations ($C_{air}$) at 4.8 atm of discharge pressure ($P_g$) were in the range of 21.04 to 25.29 mL/L. When the retention time (t) by changing the pipe line length ($L_p$) increased from 1.22 to 6.77s, the experimental micro-bubble concentrations ($C_{air}$) increased from 25.86 to 30.78 mL air/L water linearly. The dissolved and dispersed micro-bubble concentrations ($C_{air}$) are approximately 4 times more than the theoretical air solubility.

• Journal of Magnetics
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• v.20 no.4
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• pp.371-376
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• 2015

Magnetite nanoparticles were synthesized by adding excess ammonium hydroxide to a solution of iron (II) and (III) chlorides. The surfactants of oleic acid and Span 80 were applied in sequence to the magnetic particles as a combined stabilizer, and poly-${\alpha}$-olefin (PAO) 30 or 60 was used as the liquid base with a low or high viscosity, respectively. The ferrofluids were prepared with the concentrations of 200, 300, 400, and 500 mg/mL, and characterized by density, dispersion, magnetization, and viscosity. The density of the fluids increased proportionally to the concentration from 0.98 to 1.27 g/mL and 1.01 to 1.30 g/mL with PAO 30 base and PAO 60 base, and the dispersion stability was 77-95 and 81-74% for the PAO-30 and PAO-60-based fluids, respectively. The observed saturation magnetization values of the PAO-30 and PAO-60-based ferrofluids were 16 to 42 mT and 17 to 41 mT with the concentration increase in the range 200-500 mg/mL, respectively, depending upon the content of magnetic particles in the fluid. The viscosity variation of the PAO-30 and PAO-60-based ferrofluids in the temperature range $20-80^{\circ}C$ was the least with the concentrations of 400 and 300 mg/mL, respectively.

• Phonetics and Speech Sciences
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• v.6 no.4
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• pp.67-77
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• 2014

This study investigated (1) whether Korean learners of English use discourse-level prosody in L2 production as native speakers of English do, and (2) whether discourse-level prosody is also found in the Korean language, as is evident in the prosody of native speakers of English. The study compared the production of the same 15 sentences in two types of reading materials, sentence-level and discourse-level. This study analyzed the onset pitch, sentence mean pitch and pause length to examine the paratone (intonational paragraph) realization in discourse-level speech. The results showed that in L2 discourse-level prosody, the Korean speakers were limited in displaying paratone and did not made significant difference between sentence-level and discourse-level prosody. On the other hand, in L1 discourse-level text, both English and Korean participants demonstrated paratone using pitch. However, there were differences in using prosodic cues between two groups. In using pauses, the ES group paused longer before both the orthographically marked and not marked topic sentences. The KS group paused longer only before the orthographically marked topic sentence in both L1 and L2 text reading. In the comparison of sentence-level and discourse-level prosody, the topic sentences were marked by different prosodic cues. English participants used higher sentence mean pitch, and the Korean participants used higher onset pitch.

• KIEE International Transactions on Electrophysics and Applications
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• v.3C no.5
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• pp.171-176
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• 2003

For practical electrical insulation design of high temperature superconducting (HTS) power apparatuses, knowledge of the dielectric behavior of both liquid nitrogen (L$N_2$) and subcooled liquid nitrogen (SL$N_2$) are essential. To achieve SL$N_2$ at atmospheric pressure, cryostat was designed and constructed. By pumping up the L$N_2$ in the outer dewar, the temperature of L$N_2$ in the inner dewar at atmospheric pressure can be controlled. The breakdown characteristics of L$N_2$ in quasi-uniform and non-uniform electrical fields for temperatures ranging from 77 K to 65 K at atmospheric pressure and pressure ranging from 0.1 to 0.5 MPa were investigated experimentally. The experimental data suggested that the breakdown voltage (BDV) of L$N_2$ is both highly temperature and pressure dependent. We also carried out statistical analysis of the experimental results using the Weibull distribution. The Weibull shape parameter m for the sphere-to-plane electrodes in SL$N_2$ was estimated to be 11 to 18.

• Analytical Science and Technology
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• v.20 no.1
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• pp.70-77
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• 2007

Twelve chlorophenols (CPs) were extracted by liquid phase microextraction (LPME) from the industrial waste-water and analyzed by GC/MS. To establish the optimal conditions, species of extraction solvent, sample amount, pH of sample, salting out effect, a number of sampling and plunger movement speed were investigated. As a result, the linearities of calibaration curves ranged from 0.9913 to 0.9999, while LODs and LOQs were from 0.05 to 10.0 ng/mL except 2,3,4,5-tetrachlorophenol and pentachlorophenol. Using this method, 4-chloro-3-methylphenol confirmed from waste water at the concentration of 784 ng/mL. The method can be applicable to detect chlorophenols from industrial waste-water.

• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.806-809
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• 2008

온칩(on-chip) 캐쉬는 외부 메모리로의 접근을 감소시키는 중요한 역할을 한다. 본 연구에서는 내장형 시스템에 맞추어 설계된 2-레벨 캐쉬 메모리 구조를 제안하고자 한다. 레벨1(L1) 캐쉬의 구성으로 작은 크기, 직접사상(direct-mapped) 그리고 바로쓰기(write-through)를 채용한다. 대조적으로 레벨2(L2) 캐쉬는 일반적인 캐쉬 크기와 집합연관(Set-associativity) 그리고 나중쓰기(write-back) 정책을 채용한다. 결과적으로 L1캐쉬는 한 사이클 이내에 접근될 수 있고 L2캐쉬는 전체 캐쉬의 미스율(global miss rate)을 낮추는데 효과적이다. 두 캐쉬 계층간 바로쓰기(write-thorough) 정책에서 오는 빈번한 L2 캐쉬 접근으로 인한 에너지 소비를 줄이기 위해 본 연구에서는 One-way 접근 기법을 제안하였다. 본 연구에서 제안한 2-레벨 캐쉬 메모리 구조는 평균적으로 26%의 성능향상과 43%의 에너지 소비 그리고 77%의 에너지-지연 곱에서 이득을 보여주었다.