• Journal of Applied Biological Chemistry
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• v.65 no.3
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• pp.121-128
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• 2022

This study explored plant-derived natural antioxidants by evaluating the antioxidant activity of Lamiaceae plant seed extracts. Plants with the percentage of filled seeds at or above 90% and seed germination at or above 50% were selected. Of the ten species studied, the total phenolic content of the seeds was high in the species Phlomis umbrosa Turcz. (6.2 mg GAEs/g of seeds) and Elsholtzia ciliata (Thunb.) Hyl. (4.5 mg GAEs/g of seeds). The total flavonoid content of the seeds was high in E. ciliata (1.0 mg QEs/g of seeds) and P. umbrosa (0.6 mg QEs/g of seeds). Based on the EC₅₀ value of the seed extracts, 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity was high in the seeds of the plants E. ciliata (27.5 ㎍/mL), Mosla dianthera (Buch.-Ham. ex Roxb.) Maxim. (29.2 ㎍/mL), and Prunella vulgaris var. lilacina Nakai (33.3 ㎍/mL). In addition, 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activity was high in P. vulgaris var. lilacina (25.6 ㎍/mL), E. ciliata (25.9 ㎍/mL), and M. dianthera (27.6 ㎍/mL) seeds. The ferric reducing antioxidant power of the seed extracts was high in P. vulgaris var. lilacina (2910.4 µM Fe(II)/g of extract), E. ciliata (2836.2 µM Fe(II)/g of extract), and M. dianthera (2754.4 µM Fe(II)/g of extract). According to the cluster analysis based on antioxidant activity, the seeds of the ten species were classified into three groups, from group 1 with low antioxidant activity to group 3 with high antioxidant activity; E. ciliata, M. dianthera, and P. vulgaris var. lilacina were classified as group 3.

• Journal of the Korean GEO-environmental Society
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• v.18 no.11
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• pp.5-12
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• 2017

Perfluorinated compounds (PFCs) as environmental pollutants are an important environmental issue. However, little is known on the PFCs monitoring of sea waters around estuaries on the East and West Coasts of Korea. This study shows the monitoring results of PFCs in sea waters in these Coasts. Among 10 PFCs selected in this study, concentrations of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), perfluorobutane sulfonate (PFBS), and perfluorohexane sulfonate (PFHxS) in the East Coast were 9.6-50.7 ng/L (total mean${\pm}$standard deviation: $26.14{\pm}12.66ng/L$), 13.79-44.58 ng/L ($27.95{\pm}11.41ng/L$), limit of quantification (LOQ)-2.6 ng/L ($0.96{\pm}1.15ng/L$), and 2.95-11.05 ng/L ($4.25{\pm}2.57ng/L$), respectively. In the West Coast, concentrations of PFOS, PFOA, PFBS, and PFHxS were 27.66-51.71 ng/L ($36.27{\pm}7.79ng/L$), 8.97-22.53 ng/L ($14.47{\pm}4.25ng/L$), LOQ-2.27 ng/L ($1.63{\pm}0.93ng/L$), and 3.0-7.66 ng/L ($4.27{\pm}1.49ng/L$), respectly. Other PFCs were below LOQ. The result of this study provides the distribution pattern of PFCs for assessing environmental pollution in two coastal areas of Korea.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.7A
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• pp.678-682
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• 2011

In this paper, a compact log periodic dipole array (LPDA) antenna operating from 1 to 6 GHz is studied. Inverted-L shaped dipole elements are used to miniaturize the lateral size of an LPDA antenna and the spacing factor is also decreased to reduce the total length of the LPDA antenna. As the top-loading length of the inverted-L shaped dipole elements is increased, the width of the LPDA antenna is decreased but the bandwidth and the gain of the antenna are decreased. The fabricated compact LPDA antenna is printed on FR4 substrate With a dielectric constant of 4.4 and a thickness of 1.6 mm, and its size is reduced to 32% in width and 49% in length compared to a standard LPDA antenna.

• Bulletin of the Korean Chemical Society
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• v.15 no.12
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• pp.1042-1045
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• 1994

A thin film of silver ferricyanide (Ag$_3$Fe(CN)$_6$) on a platinum or gold substrates can be reduced electrochemically to the salt of silver ferrocyanide in potassium nitrate solution. The color of these films are orange and these films are shown to be electrochromic. The voltammogram is shown the asymmetry of the oxidation compared to the reduction wave under various supporting electrolytes. The standard heterogeneous electron-transfer rate for these films and bare Pt electrode were 0.49 ${\times}$ l0$^{-2}$ and 1.30 ${\times}$ l0$^{-2}$ cm/s, respectively, obtained using a rotating disc electrode. Rough D$_0$ values, evaluated from the Levich equation, for Fe(CN)$_6^{3-/4-}$ at both SF thin film and a bare Pt disc electrode were shown as 1.2l ${\times}$ l0-6 and 0.94 ${\times}$ l0$^{-6}$ cm$^2$/s, respectively. The conductivities, as determined from the slops of the i-V curves for a ca. 1 mm sample for dried SF potassium rich and deficient bulk samples pressed between graphite electrodes, were 9.34 ${\times}$ l0$^{-9}$ and 5.80 ${\times}$ l0$^{-9}$ (${\Omega}$${\cdot}$cm)$^{-1}$, respectively.

• Applied Biological Chemistry
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• v.14 no.2
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• pp.131-135
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• 1971

1. L-Tyrosine-${\alpha}$-ketoglutaric transaminase and p-hydroxyphenylpyruvic acid oxidase are distributed in Aspergillus oryzae. 2. L-Tyrosine oxidation in extracts of acetone powder, cell free extract and culture liquid of Aspergillus oryzae cultivated in the shaking culture are considerably accelerated by the addition of ${\alpha}$-ketoglutaric acid and then formation of glutamic acid was identified by chromatography method. 3. The roles of ${\alpha}$-ketoglutaric acid and pyridoxal phosphate have been shown to be an amino group acceptor in a transamination reaction. 4. Enzyme systems of an extracts of acetone powder and cell free extract also rapidly oxidized L-tyrosine and p-hydroxyphenlpyruvic acid to homogentisic acid. 5. The optimum pH for L-tyrosine-${\alpha}$-ketoglutaric acid transaminase was pH values of 6.0 and 6.5, and that for p-hydroxyphenylpyruvic acid oxidase was at pH values of 7.5.

• Biomolecules & Therapeutics
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• v.6 no.4
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• pp.383-388
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• 1998

The present study was aimed to investigate the preventive effects of rebamipide on the multiple organ dysfunction in a rat model of circulatory shock induced by bacterial endotoxin (E. coli lipopolysaccharide; LPS) in comparison with that of methotrexate. Endotoxemia for 6 hours resulted in little change in the levels of hemoglobin and neutrophils. However, treatment with methotrexate decreased significantly the numbers of circulating neutrophils. Significant increases in serum alanine aminotransferase (ALT,958 $\pm$ 250 lU/L, p<0.001) and aspartate aminotransferase (AST, 1350 $\pm$ 295 lU/L, p<0.001) levels induced by endotoxemia were significantly decreased by rebamipide and methotrexate. The increased level of lactic acid dehydrogenase (LDH) by LPS (2850 $\pm$ 467 lU/L, p<0.05) was significantly inhibited by rebamipide, but not by methot.elate. The elevated serum creatinine (1.2$\pm$0.1, p.0.05) and urea levels (55.3$\pm$6.5 mg/dL, p.0.01) by LPS were also decreased by rebamipide, but not by methotrexate. In line with these results, the plasma concentration of tumor necrosis factor-$\alpha$ (TNF-7,167 $\pm$ 20 pg/mL) was significantly increased upon injection of endotoxin at 1 hour by 1570$\pm$100 pg/mL, and declined to 312$\pm$35 pg/mL at 6 hours. The TNF-$\alpha$ level at 6 hours was significantly decreased by rebamipide to 207$\pm$8 pg/mL (P<0.05). Taken together, it is summarized that rebamipide inhibits the development of multiple ogran dysfunction by inhibition of neutrophil activation in association with inhibition of TNF-$\alpha$ formation in a murine model of endotoxemia.

• YAKHAK HOEJI
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• v.23 no.2
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• pp.125-128
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• 1979

In the formation of L(+) -glutamine from L(+) -glutamic acid-5-hydrazide, large amount of Raney-Ni was effective under normal pressure but hydrogenation or amonolysis of ester under pressure was useless. Preparation of glutamine with .alpha.-ketoglutaric acid (by way of 1, 4, 5, 6-tetrahydro-6-oxo-3-pyridazine carboxylic acid) is intersting but not so efficient in yield.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.6 no.1
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• pp.77-84
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• 2006

In strictly two-sided, commutative biquantale, we introduce the notion of Hutton $(L,\otimes)$-uniform spaces and $(L,\odot)$-uniform spaces and investigate the properties of them.

• Journal of Life Science
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• v.14 no.1
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• pp.91-97
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• 2004

As a part of our study on the improvement of anticonvulsant, here we report the synthesis of N-acyl-$\alpha$-aminosuc-cinimides 1 and N-acyl-$\alpha$-aminoglutarimides 2. (R)-Benzoic acid 4-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-ylester 6a, (R)-4-nifro-benzoic acid 4-benzyloxycarbonylamino-2- oxo-pyrrolidin-1-yl ester 6b, (R) -4-nitro-benzoic acid 4-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-yl ester 6c, and (R)-propionic acid 4-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-yl ester 6d were synthesized from (R)-2-benzyloxy carbonylamino-succinic acid 3 as a starting meterial. (R)-(3- Benzyloxycarbonylamino-2,6-dioxo-piperidin-1-yloxy)-acetic acid methyl ester 10a, (R)-(3-benzyloxycarbonylamino-2,6-dioxo-piperidin-1-yloxy)-acetic acid ethy1 ester 10b, an d (R)-2-(3-benzyloxycarbonylamino-2,6- diox o-piperidin-1-yl oxy)-propionic acid methyl ester l0c were synthesized from (R)- 3-carbobenzyloxy-amino-glutarmic acid 7 as a starting meterial. The yield, mp, IR, $^1H-NMR,\; and^{13}C$- NMR spectra of the products 6a, 6b, 6c, 6d, 10a, l0b, l0c are summarized in footnote. The biological studies of these compounds are in progress and will be reported in future.

• The Korean Journal of Ecology
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• v.17 no.2
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• pp.131-141
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• 1994

One-year-old yellow-poplar (Liriodendron tulipifera L.) and sweetgum (Liquidambar styraciflua L.) seedlings were exposed to 0.10 ${\mu}l/l\;O_3$and simulated acid rain at pH 3.0 for ten consecutive weeks. Shoot height growth (SHG), fresh weight (FWT), dry weight (DWT), apparent plastochron duration (APD) and foliar nutrient concentrations were measured. None of growth measurements, except the apparent plastochron duration (APD), were significantly affected by any treatment in yellow-poplar seedlings. APD was approximately 30% higher in seedlings exposed to $0.1{\mu}l/l\;O_3$ ＋ pH 5.6 solution than any other treatment. Ozone significantly reduced SHG of sweetgum seedlings by 24% at the end of the ten-week fumigation. There were also significant effects of single and combined effects of ozone and simulated acid rain on APD in sweetgum. APD was significantly increased by 19.8% and 25.7% in seedlings exposed to $0.1{\mu}l/l\;O_3$ and pH 5.6 solution, respectively, and resulted in 46.1% higher APD in seedlings exposed to $0.1{\mu}l/l\;O_3$ + pH 5.6 solution compared with seedlings exposed to $0.0{\mu}l/l\;O_3$ ＋ pH 3.0 solution. Phosphorus and sulphur were significantly greater in seedlings exposed to simulated rain at pH 3.0 compared with pH 5.6 for both species. Foliar S concentration was higher in seedlings exposed to $0.0{\mu}l/l\;O_3$ ＋ pH 3.0 than in seedlings exposed to any other treatment in sweetgum. Ozone significantly increased Ca in sweetgum seedlings, however, ozone reduced Ca in yellow-poplar. Ozone also reduced S and Mg in sweetgum seedlings.