• Title/Summary/Keyword: Kyungpook

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The Change of Vascular Reactivity in Rat Thoracic Aorta 3 Days after Acute Myocardial Infarction (흰쥐에서 급성심근경색 3일 후 흉부 대동맥 혈관 반응성의 변화)

  • Lee, Sub;Roh, Woon-Seok;Jang, Jae-Seok;Bae, Chi-Hoon;Park, Ki-Sung;Lee, Jong-Tae
    • Journal of Chest Surgery
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    • v.42 no.5
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    • pp.576-587
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    • 2009
  • Background: The up-regulation of the nitric oxide (NO)-cGMP pathway might be involved in the change of vascular reactivity in rats 3 days after they suffer acute myocardial infarction. However, the underlying mechanism for this has not been clarified. Material and Method: Acute myocardial infarction (AMI) was induced by occluding the left anterior descending coronary artery (LAD) for 30 min (Group AMI), whereas the sham-operated control rats were treated similarly without LAD occlusion (Group SHAM), The concentration-response relationships for phenylephrine (PE), KCl, acetylcholine (Ach) and sodium nitroprusside (SNP) were determined in the endothelium intact E(+) and endothelium denuded E(-) thoracic aortic rings from the rats 3 days after AMI or a SHAM operation. The concentration-response relationships of PE in the E(+) rings from the AMI rats were compared with those relationships in the rings pretreated with nitric oxide synthase (NOS) inhibitor $N{\omega}$-nitro-L-arginine methyl ester (L-NAME) or the cyclooxygenase inhibitor indomethacin. The plasma nitrite/nitrate concentrations were checked via a Griess reaction. The cyclic GMP content in the thoracic aortic rings was measured by radioimmunoassay and the endothelial nitric oxide synthase (eNOS) mRNA expression was assessed by real time PCR. Result: The mean infarct size (%) in the rats with AMI was $21.3{\pm}0.62%$. The heart rate and the systolic and diastolic blood pressure were not significantly changed in the AMI rats. The sensitivity of the contractile response to PE and KCl was significantly decreased in both the E(+) and E(-) aortic rings of the AMI group (p<0.05). L-NAME completely reversed these contractile responses whereas indomethacin did not (p<0.05). Moreover, the sensitivity of the relaxation response to Ach was also significantly decreased in the AMI group (p<0.05). The plasma nitrite and nitrate content (p<0.05), the basal cGMP content (p<0.05) and the eNOS mRNA expression (p=0.056) in the AMI rats were increased as compared with the SHAM group. Conclusion: Our findings indicate that the increased eNOS activity and the up-regulation of the NO-cGMP pathway can be attributed to the decreased contractile or relaxation response in the rat thoracic aorta 3 days after AMI.

Clinical Features of Pulmonary Langerhans Cell Histiocytosis in Korea (국내 폐 랑게르한스세포 조직구증(Pulmonary Langerhans Cell Histiocytosis)의 임상양상)

  • Kim, Chul;Jeong, Sung Hwan;Shim, Jae Jeong;Cha, Seung-Ick;Son, Choonhee;Chung, Man Pyo;Park, Hye Yoon;Kim, Young Whan;Park, Jong Sun;Uh, Soo-Taek;Park, Choon Sik;Kim, Dong Soon;Cho, Kyung Wook;Song, Jin Woo;Jegal, Yang Jin;Park, Moo Suk;Park, Byung Hoon;Lee, Jin Hwa;Hur, Jin Won;Yum, Ho-Kee;Lee, Hong-Lyeol;Park, Yong Bum
    • Tuberculosis and Respiratory Diseases
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    • v.66 no.2
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    • pp.98-103
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    • 2009
  • Background: Pulmonary Langerhans cell histiocytosis (PLCH) is characterized by a proliferation of Langerhans cells and this results in granulomas that involve multiple organs of the body. Because the incidence of PLCH is very low in Korea and worldwide, collecting the clinical data of patients with PLCH nationwide is needed to determine the clinical features of Korean patients with PLCH. Methods: The patients with PLCH confirmed by biopsy at any body site were included and the patients should have lung lesions present. A questionnaire that had items on the symptoms, lung function tests, the roentgenographic findings and the treatment was collected retrospectively at a Korean ILD Research Meeting. Results: A total of 56 cases were collected. The number of males and females was 48 and 8, respectively, and their median age was 43 years (range: 18-67 years). The patients were current or ex-smokers in 79% of the cases. The most frequent symptom was coughing (39%), followed in decreasing order by dyspnea (38%), sputum (20%) and chest pain (20%). Pneumothorax was observed in 16 (29%) patients. Lung function tests showed a normal, restrictive, mixed or obstructive pattern in 26 (61%), 7 (16%), 7 (16%) and 3 patients (7%), respectively. Nodular-cystic lesion was most frequently observed in 59% of the patients on HRCT. The lung lesions were located in the middle and upper lobes in almost the cases. The median follow-up period was 90 months (range: 1-180 months) and only two patients died during this period. Conclusion: This study provides a national survey of the patients with PLCH during a long follow-up period.

Analysis of the Case with Serial Killer Young Cheol Yoo (유영철 연쇄살인사건 분석)

  • Lee, Jin-Dong;Lee, Sang-Han
    • Journal of forensic and investigative science
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    • v.2 no.1
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    • pp.32-51
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    • 2007
  • Serial violent crimes have occurred more frequently. Additional attention is paid to relevant areas in which discussions has also increased. This study analyzed Young-cheol Yoo, serial killer case. Two of Yoo's crimes were studied for modus operandi. The cases selected were the premeditated break-in homicide of upper-class elderly people and the impulsive homicide of the Hwanghak-Dong street vendor. Crime motives, targets, times, places, means and methods were analyzed. Profiling techniques in Young-cheol Yoo cases were evaluated and the problems discovered during investigation were discussed. The followings are the findings of the analysis of the serial killer Yoo cases. Yoo exhibited a hatred toward the rich, the elderly, and women as well as a fear of diseases and death. Yoo's crime targets were the elderly residing in wealthy houses, street vendors and prostitutes. The numbers of victims were: 3 men and 5 women victims in 4 homicide cases involving the elderly residents in wealthy houses; one man in 1 street vendor homicide case 11 women in 11 prostitute homicide cases, so total 20 persons were murdered in 16 cases. The time of the crimes were between 10 am and noon in the homicide cases of the elderly and very late at night or early in the morning in the prostitute homicide cases. Means and methods facilitated include the use of a knife as a threat and a hammer made by Yoo to strike the head and face of victims. In the homicide cases involving the elderly, he attempted to disguise the crime scene as a burglary or committed arson to destroy the evidence; in the prostitute homicide cases, bodies were mutilated and buried in secret. 1) Generally each serial killer case has different characteristics, motives, and purposes; while some serial killer cases involve similar methods, others use different methods. Unlike other crimes, serial killers' characteristics and tastes are very different, so it is difficult to explain serial killings based on a specific model. It is important to accurately capture modus operandi of each serial killing and for detectives to familiarize themselves with them. The process of tracing and use of imagination which follows a serial killer's psychology and thought must be used to find out what kind of thoughts pushed the killer to commit the crime. In order to investigate and research difficult subjects such as serial killing, various methods, skills, and relevant knowledge should be studied, and institutional endeavors should go hand in hand with individual efforts.

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An Analysis of the National Suicide Rate in Korea during 2005 (2005년 전국 자살실태 분석)

  • Kim, Gi-Jeong;Kwak, Jyung-Sik
    • Journal of forensic and investigative science
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    • v.2 no.1
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    • pp.5-22
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    • 2007
  • From the numerous social problems generated by the unbalanced social development and the social trend of belittling life overall, we found the causes of suicide getting worse in its seriousness day by day. In reality, the problem has been approached in a collateral level in contrast with other social problems. There have been an active involvement in studying the definition, causes and ways of prevention of suicide theoretically until now. However, different from other social problems, it is almost impossible to treat or fix the problem of suicide. Only ways to treat or fix the problem is when the suicide has ended in failure. Thus, this study intends to examine the suicide rate among the total accidents during the year 2005, perform the analyses on the actual causes according to the relations such as the means of suicide, occupation, age group, educational background, etc. In order to present a solution to the issue of suicide becoming serious each day. Among the total accidents in 2005, the suicide rate came out to be approximately 52.4%. Among the result, 52.4%, male with 69% resulted higher than female with 31%, which appears to be related to the social functions. While men tends to take more active(80%) means of suicide like jumping off, poison, hanging, etc., women tends to take more passive(60%) means of suicide like sleeping pills, slitting wrist, etc. In terms of the cause, pessimism, illness, denial, mental disorder, etc resulted more than 75%, and there were many cases of suicide after exhibiting the signs of depression. Also there were higher suicide rate of the unemployed engaged in direct labor with educational background lower than college level related to the pessimism regarding the family living cost. We were able to determine the recent increase in the suicidal tendency of the educated people higher than the college level and the retired people with depression caused by the sudden change in social status. Overall there are several reasons for suicide, however, in most cases the signs of depression were exhibited until the final suicide, which tells us the serious psychological problem of suicide. Assuming that the current development of suicide will continue in future, the result of this study will guide the corresponding social policies, be utilized in preparing the insurance or management at the national level dealing with the real social problems that are not just a conflict of an individual, but could spread like a fad and become much bigger than the present by the continuous support at the environmental, social and political levels, and be utilized as the basic data to establish the research plan.

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Ecophysiological Characteristics of Chenopodiaceous Plants - An Approach through Inorganic and Organic Solutes - (명아주과 식물의 생리생태학적 특성 - 무기 및 유기용질을 통한 접근 -)

  • Choo, Yeon-Sik;Song, Seung-Dal
    • The Korean Journal of Ecology
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    • v.23 no.5
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    • pp.397-406
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    • 2000
  • In order to clarify the ecophysiological characteristics of Chenopodiaceae which widely distribute on saline and arid habitats, we collected 10 chenopodiaceous plant species, examined their inorganic and organic solute patterns, and confirmed several common physiological characteristics. In spite of high soil Ca/sup 2+/ contents, chenopodiaceous plants had a little water-soluble Ca within cells, but contained high contents of acid-soluble Ca particularly as a result of Ca-oxalate formation. These plant species also showed accumulation of inorganic ions such as K/sup +/, NO₃/sup -/ and Cl/sup -/, and Na/sup +/especially in saline habitats instead of K/sup +/ Meanwhile, with respect to nitrogen metabolism they retained high N contents in leaves, but showed very low amino acid contents. Additionally, they contained very little proline known to act as a cytoplasmic osmolyte. To ascertain whether this physiological characteristics in the field also can be found under controlled conditions, 7 chenopodiaceous plants (Atriplex gmelini, Corispermum stauntonii, Salicornia herbacea, Suaeda aspayagoides, Suaeda japonica, Chenopodium album var. centrorubrum, C. serotinum) were selected and cultivated under salt treatments. As well as field-grown plants, selected plant species showed similar solute pattern in growth experiment. In summary, the family of Chenopodiaceae represents the following physiological properties; high storage capacity for inorganic ions (especially alkali cations, nitrate and chloride), oxalate synthesis to maintain lower soluble Ca contents within cytoplasm, and low contents of amino acids. In addition to some characteristics mentioned above, the physiological plasticities of Chenopodiaceae which can properly regulate their ion and solute pattern according to soil conditions may enable its representative to grow in dry sand dune and salt marsh habitats.

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An Analysis of 10th Grade Students' Understanding of Concepts about the Plates' Motions according to the Level of Spatial Ability (공간능력의 차이에 따른 10학년 학생들의 판 운동 관련 개념에 대한 이해 분석)

  • Lee, Hyo-Nyong;Cho, Hyun-Jun;Park, Mi-Ran
    • Journal of the Korean earth science society
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    • v.33 no.4
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    • pp.360-375
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    • 2012
  • The purpose of this study was to compare 10th grade students' understanding of concepts about the plates' motions depending on the different spatial ability. Based on previous studies and literature reviews, two instruments were selected and used in this study. The Spatial Perception Test developed in Korean Testing Center was applied to measure students' spatial ability. Another instrument for testing students' understandings of plates' motions consists of a total of 10 items. The instruments were distributed to 118 students who were 10th graders in metropolitan city. The results are as follows: First, a correlation coefficient between conceptual understanding of plates' motions and spatial ability was r=0.439 (p<.01). It indicates that conceptual plates' motions and spatial ability have a moderate relationship. The students were divided into two groups (high and low) by spatial ability. The independent t-test was performed and reveals that the statistically significant difference between high and low groups. On the other hand, the 6 students (3 higher spatial ability students and 3 lowers) were selected and interviewed individually to find the differences in their understanding of the concept of plates' motions. The findings from interviews indicate that most students recognized about concepts of trench and ocean ridge, a rise and drop of the mantle, and divergent and convergent boundaries. However, students had misconceptions about section of trench and ocean ridge. In addition, the students who had higher spatial ability knew the more proper concepts about the creation and extinction of plate, crustal movements, and bottom of the ocean extension, whereas the students who had the lower spatial ability had misconceptions.

A survey on the nutrition knowledge, dietary behavior and satisfaction of dietary education of high school female students (대구.경북지역 여고생의 영양지식, 식습관 및 식생활교육 만족도 조사)

  • Kim, Yun-Hwa
    • Journal of Korean Home Economics Education Association
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    • v.24 no.1
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    • pp.21-36
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    • 2012
  • The purpose of this study was to determine the direction of dietary education in school. A questionnaire that identified nutrition knowledge, dietary behavior, help degree to real-life of dietary education, and dietary education satisfaction were developed based on a review of the literature. The subjects consisted of 409 high school female students in Daegu and Gyeongbuk area. The total mean score of nutrition knowledge was 9.2/15.0. The score of nutrition knowledge was correlated with school type, grade, number of brothers and sisters, and school record(p<0.05). The dietary behavior was 3.30/5.00, showing difference from school type, father's occupation, and economic level(p<0.05). It was also found that the higher the score in nutrition knowledge, the higher the score in dietary behavior(p<0.001). The total mean score of the dietary education satisfaction and help degree to real-life of dietary education for high school female students were same as 3.39/5.00. The biggest reason of unsatisfaction on dietary education was lack of class time. The form of instruction they want to get was the class for experiment and practice. The score of the dietary education satisfaction was correlated with help degree to real-life of dietary education, nutrition knowledge, and dietary behavior(p<0.01). Therefore, more active dietary education should be give to high school female students to meet the intellectual need and successful dietary behavior. Also dietary education would be needed to relate with their home.

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Analyses of the Test Problems for Admission at the Science Education Center for Gifted Youth (과학영재교육센터 학생선발문항 분석 및 선발방법에 대한 제언)

  • Lee, Sang-Bub;Lee, Kwang-Pill;Choi, Sang-Don;Hwang, Suk-Geun
    • Journal of The Korean Association For Science Education
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    • v.19 no.4
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    • pp.604-621
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    • 1999
  • We analyze the admission test problems used in 1998 at the Science Education Center for Gifted Youth at Kyungpook National University (SECGY, KNU). The test consists of two parts, an evaluation of the scientific thinking skills and an evaluation of the achievement for Mathematics and Sciences, the former of which includes evaluations of scientific process skills and logical thinking skills. The problems for the test of scientific thinking skills were developed and standardized by the Korea Education Development Center, while those of the achievement for Mathematics and Sciences were made at SECGY. We calculate the indices of the difficulty and discrimination for each problem to determine whether or not the test is appropriate to apply for selecting number of gifted students among the recommended students from 389 middle schools in Taegu-city and Kyungsang-pook-do Province. We find that both indices of most problems for the test of scientific thinking skills were out range of the appropriate level and. moreover, even those problems which fall into the appropriate range showed very low efficiencies for distractors. We, thus, conclude that the problems of the test of scientific thinking skills are inappropriate to use as a test for admission to SECGY. On the other hand, the problems of the achievement test showed extreme results; the Mathematics problems appeared to be too difficult, whereas the Physics problems appeared too easy. However, overall scores showed a normal distribution, indicating that those problems played crucial role in selecting gifted students. We finally propose several suggestions in developing the test problems and in selecting students at the SECGY.

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An Approach of Ecological Niche to Analysis of Recognition of 5th Grade Elementary students for Conception of Photosynthesis (생태 지위적 접근을 통한 5학년의 광합성 개념 분석)

  • Jeong, Jae-Hoon;Kim, Young-Shin
    • Journal of The Korean Association For Science Education
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    • v.31 no.4
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    • pp.513-527
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    • 2011
  • There have been studies about conceptual ecology making a profound study of conceptual changes in learners' cognitive structure. Because learners' cognitive structure have been compared to ecology, it is natural to think that conception in learner's cognitive structure have a niche as species in ecology have niches. Therefore, it is necessary to study niche approach about conception that learners recognize in their cognitive structure. The purposes of this study were to identify relationships among conceptions that 5th grade elementary school students recognize about photosynthesis and to identify how these relationships among conceptions about photosynthesis change before and after a class of photosynthesis in curriculum in terms of an approach of ecological niche which are composed of 3 domains - diversity of conceptions, relevance and frequency rate of conceptions, and competition among conceptions. Open ended questionnaire was developed by 4 fields: photosynthetic place, photosynthetic products, photosynthetic materials needed and environment factors of photosynthesis. The subjects sampled in this study were 310 5th grade elementary students in 5 cites. Before and after classes in photosynthesis in science curriculum, students were asked to write down conceptions that they knew about the 4 fields of photosynthesis of questionnaire and to write down scales of relevance from 1 to 30 about how they think the conceptions are related to the field of photosynthesis. The results of this study showed the following: First, most students have had a variety of conceptions and commonly recognized 'light' and 'water' as concepts in photosynthesis. Second, students still recognized their preconceptions like 'soil' and 'root,' etc. that were far from scientific conceptions of photosynthesis although they took classes in photosynthesis. Third, students needed to take the various strategies of teachers because they did not recognized scientific conceptions appropriately about photosynthetic fields. Fourth, it appeared that photosynthetic conceptions recognized by students had status in terms of relevance and frequency rate of conceptions, and competition among conceptions, and that they looked like the niche of conceptions in their conceptual ecologies.

An Analysis of the Operational Time and Productivity in Whole-tree and Cut-to-Length Logging Operation System (전목 및 단목 집재작업시스템에서 작업시간 및 공정 분석)

  • Kim, Min-Kyu;Park, Sang-Jun
    • Journal of Korean Society of Forest Science
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    • v.101 no.3
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    • pp.344-355
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    • 2012
  • This study was conducted to analyze on the operational time and productivities of logging operations in whole-tree logging operation system by tower-yarder and swing-yarder, and in cut-to-length logging operation system by excavator with grapple in order to establish the efficient logging operation system and to spread logging operation technique. In the analysis of operational time, in case of whole-tree logging operation system, the felling time was 46.6 sec/cycle by chain saw, the yarding time was 480.6 sec/cycle by tower-yarder, the yarding time was 287.4 sec/cycle by swing-yarder and the bucking time was 155.14 sec/cycle by chain saw. In case of the cut-to-length logging operation system, the felling and bucking time was 225.65 sec/cycle by chain saw, the cut-to-length extraction time was 4,972 sec/cycle by excavator with grapple, the branches and leaves extraction time was 3,143 sec/cycle by excavator with grapple. The forwarding time was 4,688 sec/cycle by wheel type mini-forwarder, the forwarding time was 2,118 sec/cycle by excavator with grapple and small forwarding vehicle. In the analysis of operational productivities, in case of whole-tree logging operation system, the average felling performance was $57.89m^3/day$ by chain saw, the average yarding performance was $20.3m^3/day$ by tower-yarder, $31.55m^3/day$ by swing-yarder respectively, the average bucking performance was $20.3m^3/day$ by chain saw. In case of the cut-to-length logging operation system, the average felling and bucking performance was $11.96m^3/day$ by chain saw, the average cut-to-length extraction performance was $34.75m^3/day$ by excavator with grapple, the average branches and leaves extraction performance was $37.66m^3/day$ by excavator with grapple, the average length of operation road construction was 73.8 m/day by excavator with grapple. The average forwarding performance by wheel type mini-forwarder and the average forwarding performance by excavator with grapple and small forwarding vehicle was $15.73m^3/day$ and $65.03m^3/day$, respectively.