• Journal of the Korean Magnetic Resonance Society
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• v.22 no.1
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• pp.1-9
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• 2018

Among several NMR hyperpolarization techniques, parahydrogen-based hyperpolarization technique is recently extensively utilized to enhance the sensitivity of the conventional NMR/MRI spectroscopy. Two mostly investigated research topics are PHIP (Parahydrogen Induced Polarization) and SABRE (Signal Amplification By Reversible Exchange), which are commonly using the parahydrogen as the source of hyperpolarization. Those researches have been considered as the promising techniques that could provide hyperpolarized states on the ambient substrates including biologically important materials. Therefore, based on their potentials, we briefly reviewed several important experimental results on those topics after introducing the basic principle of parahydrogen and its generation with conceptual explanations. We hope this review will broaden the parahydrogen-based hyperpolarization transfer study on many researches in Korea.

• Survey Research
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• v.2 no.2
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• pp.1-16
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• 2001

This paper intends to provide some guidelines for the articles to be published in Survey Research. For that purpose, we review the research articles published in Public Opinion Quarterly in 1991, 1995, and 2000. and identify the characteristics and the analytical methods and data used in these researches. Articles in Public Opinion Quarterly have some implications to the Korean survey research community in such a way that the types of researches to improve survey qualities and meta analyses of previously conducted survey researches seem to be the most useful and necessary at present.

• Journal of the Korean School Mathematics Society
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• v.7 no.2
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• pp.67-79
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• 2004

Researchers in education intend and aspire to improve education practice. Researches should provide practical knowledge, instruments, teaching/learning skills which are needed in real educational environments. Research should closely related to practice. Design-experiment researches intend to promote and help education innovation. A variety of design experiment researches are presented with their characteristics, methods, goals, principles, case studies, prospects.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2002.05a
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• pp.334-341
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• 2002

As the interest in internet business increases, effective web site evaluation is in order. While web site evaluation is supposed to be based on feasible applicability and trust-worthy criteria. many researches on web site evaluation fails to rover the various business models and consider corporate-activity-related features. Besides, dealing with the limited aspects such as design and cognitive science is something to be desired on the previous researches. Therefore, This paper presents internet web site evaluation framework not only based on existing researches and analysis but also reflecting corporate strategies. The framework includes web sites contents, design, operation and management-related factors, and it is applied to companies to validate its applicability.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1999.06a
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• pp.11-14
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• 1999

The forthcoming century will be the "era of cyber society" . In a virtual environment, a cyber character plays the role of an agent for the human being. In this paper, we introduce active researches of industries, universities, and research institutes in Korea. After Adam Soft Inc. presented a cyber singer,“Adam”, a few cyber characters have succeeded commercially through Internet, TV, CF, movies and etc. Some universities had their own characters to make fundamental researches in the fields of modeling, motion control, and VR. Research institutes have been funded recently to a cyber character related researches. This paper briefly reviews the recent research works, and future trends in Korea. in Korea.

• Journal of the Korean Society of Food Culture
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• v.19 no.3
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• pp.295-312
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• 2004

This study is to investigate the trend of researches on food and culture from 1990 to 2003. With a literary approach, this paper analyzes how many papers were published and what was the major research subject. We classified the journals published during this time into 10 different categories and we are to grasp a research trend. 1) Historical approach on the traditional food and food habit; 2) Globalization of Koran food; 3) Use and preparation for traditional food; 4) Table setting and table manner; 5) Provincial cuisine; 6) Traditional festive food or celebratory meal; 7) Religious food; 8) Fusion food; 9) Food and culture in foreign countries and food habit of Korean people living abroad; 10) Studies related with satins out. It was revealed that 268 papers(=ps) were published. Eating out was the most frequently reported subject(100 ps), followed by provincial cuisine(54 ps), use and preparation for traditional food(49 ps), food habit for foreign people and Korean people living abroad(22 ps). Researches on these 4 topics have been accelerated since the late half of 1990s. This reflects the social factors such as rapid growth of food service industry, settlement of local autonomy, popularization of leisure activities and accelerated introduction of foreign food and culture. Half of the studies on the eating out dealt with eating out behavior. And 30 papers were reports on the food service industry situations. More than half of the studies on the provincial cuisine(26 ps) were concentrated on digging out recipes. Studies on the use and preparation for traditional food were mainly about what kind of food and how often the food is used(17 ps). Kimchi was the most frequently studied food. There were 11 papers regarding food and culture in foreign countries. Most of the authors were historians or linguists. Food habit of Korean people living abroad were investigated in 7 papers. There was few studies on fusion food, table setting and table manner. This doesn't meet with increasing demand for specialized information in then fields. Researches on the traditional festive food or celebratory meal(5 ps) and religious food(9 ps) were negligible. Papers on the historical approach to the traditional food and food habit were limited(12 ps). Moreover, most of them were patchwork of existing literatures. Continuous researches to exploit the historical facts based on literary proof should be tried with patience. Otherwise, the papers will copy the hackneyed knowledge repeatedly. Globalization of Korean food means the development of Korean food for foreign people and export of them worldwide. Only 16 papers were reported on this subject, 14 of them were published after 2000, 8 of them were surveys on the foreigners' food preference. In order to get practical informations on what we develope and how we sell for the foreign customers, profound research on their food habit should be done.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1990.10a
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• pp.91-98
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• 1990

This paper reviews the previous researches related to the effects of whole-body vibration on human performance. The physiological effects of vibration were reviewed in the first part, and the effects of vibration on vision and manual control performance were discussed. the relationships between vibration and ride quality were also discussed. ISO-2631 was briefly reviewed, and cautions and limitations were discussed to avoid misinterpretations when we accomodate Korean population to this standard. Further researches were recommended to get better understanding of response characteristics of Korean to whole-body vibration.

• Journal of architectural history
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• v.20 no.1
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• pp.61-75
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• 2011

This study aims to investigate the changing aspects about research methodology of stone pagoda from the period of Japanese colonial to now. There were the differences in purpose, method and analysis of the research according to each period. In Japanese colonial period, the purpose of research was to make lists of almost stone pagodas in Korea. Following this, Japanese researchers conducted detailed research for academic purpose. They took measurements of stone pagodas and made drawings. After liberation the research was focused on the relics contained in pagodas. They proceeded to investigate the inner relics in order to attract the attention of the people. In the late 1900's, the repair works of cultural heritages were increased. Many reports of the repair works were released and sent to administration offices. The reports contained the change aspects of situation between before work and after with drawings or simple investigation documents. In the 1990's, the restoration works for important stone pagodas were started by the National Research Institute of Cultural Heritage. Since then, researches from various way - architectural and conservational researches about historical interpretation, shape, structure, proportion, technique, etc. - progressed for careful restoration and accurate study. In Recent years, various professional organizations(in the field of structure, physics, chemistry, biology, lithology, etc.) started to join the researches. Researches conducted studies directly with the stone pagodas, as well as conducting indirect studies with the stone pagodas, such as the structural stability of stone pagodas, the characteristics of rock, and conservation chemicals. Today the research project 'The preservation project of stone cultural property' is being conducted by the National Research Institute of Cultural Heritage. The purpose of this project is to gain more detailed and accurate investigation documents to be provided for the people. In conclusion, researches from various fields must be included in the research. Furthermore, a synthetic study should be done through comparing similar characteristics or different characteristics among many research results.

• Molecular & Cellular Toxicology
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• v.3 no.2
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• pp.107-112
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• 2007

o-Nitrotoluene is used to synthesize artificial dyes and raw materials of urethane resin. In this study, we have carried out in vitro genetic toxicity tests and microarray analysis to understand the underlying mechanisms and the mode of action of toxicity of onitrotoluene. TA1535 and TA98 cells were treated with o-nitrotoluene to test its toxicity by basic genetic toxicity test. Ames and two new in vitro micronucleus and COMET assays were applied using CHO cells and L5178Y cells, respectively. In addition, microarray analysis of differentially expressed genes in L5178Y cells in response to o-nitrotoluene was analyzed using Affymatrix genechip. The result of Ames test was that o-nitrotoluene treatment did not increase the mutations both in base substitution strain TA1535 and in frame shift TA98. o-Nitrotoluene has not increased micronuclei in CHO cells. But onitrotoluene increased DNA damage in L5178Y cell. Two-hundred two genes were initially selected as differentially expressed genes in response to o-nitrotoluene by microarray analysis and forty four genes among them were over 2 times of log fold changed. These forty four genes could be candidate biomarkers of genetic toxic action of o-nitrotoluene related to induction of mutation and/or induction of micronuclei and DNA damage. Further confirmation of these candidate markers related to the DNA damage will be useful to understand the detailed mechanism of action of o-nitrotoluene.

• Molecular & Cellular Toxicology
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• v.3 no.2
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• pp.90-97
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• 2007

8-Hydroxyquinoline is used as antibacterial agent and antioxidant based on its function inducing the chelation of ferrous ion present in host resulting in production of chelated complex. This complex being transported to cell membrane of bacteria and fungi exerts antibacterial and antifungal action. In this study, we have carried out in vitro genetic toxicity tests and microarray analysis to understand the underlying mechanisms and the mode of action of toxicity of 8-hydroxyquinoline. TA1535 and TA98 cells were treated with 8-hydroxyquinoline to test its toxicity by basic genetic toxicity test, Ames and two new in vitro micronucleus and COMET assays were applied using CHO cells and L5178Y cells, respectively. In addition, microarray analysis of differentially expressed genes in L5178Y cells in response to 8-hydroxyquinoline were analyzed using Affymatrix genechip. The result of Ames test was that 8-hydroxyquinoline treatment increased the mutations in base substitution strain TA1535 and likewise, 8-hydroxyquinoline also increased mutations in frame shift TA98. 8-Hydroxyquinoline increased micronuclei in CHO cells and DNA damage in L5178Y. 8-Hdroxyquinoline resulted in positive response in all three tests showing its ability to induce not only mutation but also DNA damage. 783 Genes were initially selected as differentially expressed genes in response to 8-hydroxyquinoline by microarray analysis and 34 genes among them were over 4 times of log fold changed. These 34 genes could be candidate biomarkers of genetic toxic action of 8-hydroxyquinoline related to induction of mutation and/or induction of micronuclei and DNA damage. Further confirmation of these candidate markers related to their biological function will be useful to understand the detailed mode of action of 8-hydroxyquinoline.