• Journal of Microbiology and Biotechnology
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• v.34 no.8
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• pp.1711-1717
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• 2024

This study evaluates the efficacy of a decellularized intestine tissue-derived extracellular matrix (Intestine ECM) as a scaffold for culturing colorectal cancer (CRC) organoids and establishing cell-derived xenograft (CDX) models, comparing its performance to traditional Matrigel. Intestine ECM demonstrates comparable support for organoid formation and cellular function, highlighting its potential as a more physiologically relevant and reproducible platform. Our findings suggest that Intestine ECM enhances the mimetic environment for colon epithelium, supporting comparable growth and improved differentiation compared to Matrigel. Moreover, when used as a delivery carrier, Intestine ECM significantly increases the growth rate of CDX models using patient-derived primary colorectal cancer cells. This enhancement demonstrates Intestine ECM's role not only as a scaffold but also as a vital component of the tumor microenvironment, facilitating more robust tumorigenesis. These findings advocate for the broader application of Intestine ECM in cancer model systems, potentially leading to more accurate preclinical evaluations and the development of targeted cancer therapies.

• Korean Journal of Pharmacognosy
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• v.47 no.3
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• pp.246-250
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• 2016

Pinus densiflora contained diverse phenol compounds like flavonoid, phenylpropanoid and tannin. PineXol$^{(R)}$ is nutraceutical preparation which was treated from bark of Pinus densiflora. Validation and contents determination of taxifolin, (+)-catechin and procyanidion B1 for the preparation of Pinus densiflora (PineXol$^{(R)}$) were confirmed using High-Performance Liquid Chromatography (HPLC). As a result, content of taxifolin, (+)-catechin and procyanidin B1 were, respectively 4.90%, 2.35% and 8.19%. These analysis method and results could be used as important basic data for the preparation of Pinus densiflora.

• Journal of the Korean Institute of Rural Architecture
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• v.24 no.3
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• pp.39-46
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• 2022

This study aims to derive basic living service facility items in rural areas and construct related spatial data. To do this, a literature review on the laws and systems related to the residential environment and services in rural areas, rural spatial planning, and the 'Rural Convention' strategic plan reports for the Jeolla and Gyeongsang Region in 2021 was conducted. Primary data collection and review on the list of basic living service items in rural areas derived from the analysis were conducted. After data collection, 12 sectors and 44 types of rural basic living service items were derived; the data selection was carried out based on the clarity of the subject of data management, whether it was established nationwide, whether it was disclosed and provided, whether it was periodically updated, and whether it was an underlying law. Afterwards, data on the derived rural basic living service items were constructed. Afterwards, spatial data on the derived rural basic living service items were constructed. Because open data provided through various institutions were employed, data structure unification such as data attribute values and code names was needed, and abnormal data such as address errors and omissions were refined. After that, the data provided in text form was converted into spatial data through geocoding, and through comparative review of the distribution status of the converted data and the provided address, spatial data related to rural basic living services were finally constructed for about 540,000 cases. Finally, implications for data construction for diagnosing rural living areas were derived through the data collection and construction process. The derived implications include data unification, data update system establishment, the establishment of attribute values necessary for rural living area diagnosis and spatial planning, data establishment plan for facilities that provide various services, rural living area analysis method, and diagnostic index development. This study is meaningful in that it laid the foundation for data-based rural area diagnosis and rural planning, by selecting the basic rural living service items, and constructing spatial data on the selected items.

• Journal of the Korean Statistical Society
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• v.13 no.2
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• pp.73-80
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• 1984

In this paper, likelihood-ratio test has been derived for testing multisample sphericity in complex multivariate Gaussian populations. The $h^{th}$ moment of the test statistic is given and its exact distribution has been derived using inverse Mellin transform. Asymptotic distribution of the statistic is also given.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2008.10a
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• pp.184-184
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• 2008

• Bulletin of the Korean Mathematical Society
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• v.43 no.4
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• pp.805-812
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• 2006

In this paper we find a suitable bound for the number of commutators which is required to express every element of the derived group of a solvable group satisfying the maximal condition for normal subgroups. The precise formulas for expressing every element of the derived group to the minimal number of commutators are given.

• Journal of the Korean Institute of Intelligent Systems
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• v.9 no.6
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• pp.644-649
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• 1999

in this paper we introduce the notions of fuzzy r-adherent points fuzzy r-accumulation points and fuzzy r-derived sets in fuzzy topological spaces and investigate some of their properties.

• Journal of the Korean Data and Information Science Society
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• v.10 no.2
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• pp.299-311
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• 1999

In this paper the single and product moments of order statistics of the doubly truncated Rayleigh distribution are studied. Some recurrence relations of order statistics are derived. Using order statistics, also characterization of the Rayleigh distribution are derived.

• Communications of the Korean Mathematical Society
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• v.20 no.2
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• pp.359-364
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• 2005

We give another characteristic feature of the set of phantom maps: After constructing an isomorphism between derived functors, we show that the set of homotopy classes of phantom maps could be restated as the extension product of subinverse towers induced by the given inverse towers.

• Journal of the Korean Statistical Society
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• v.15 no.1
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• pp.62-70
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• 1986

In this paper distribution of the determinant of B-statistic in the complex case has been derived in terms of incomplete gamma functions. Asymptotic expansion of the distribution has also been derived.