• Knowledge Management Research
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• v.2 no.1
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• pp.109-132
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• 2001

The purpose of this article is to develop a dynamic model of organizational capabilities and knowledge creation, and at the same time identify the organizational capability factors for effective knowledge creation, by empirically analyzing the history of new Quinolone antibacterial drug compound (LB20304a) discovery process at LG, as a case in point. Major findings of this study are as follows. First, in a science-based area such as drug development, the core of successful knowledge creation lies in creative combination of different bodies of scientific explicit knowledge. Second, the greater the difficulty of learning external knowledge, the more tacit knowledge is needed for the recipient firm to effectively exploit that knowledge. Third, in science-based sector such as pharmaceutical industry, the key for successful knowledge creation lies in the capability of recruiting and retaining star scientists. Finally, for effective knowledge creation, a firm must keep its balance among three dimensions of organizational capabilities: local, process, architectural capabilities.

• The Korean Journal of Emergency Medical Services
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• v.25 no.3
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• pp.93-109
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• 2021

Purpose: This study aims to investigate the knowledge and attitudes regarding adverse drug reactions (ADR) of emergency medical services (EMS) students, so that suggestions for further education on ADR can be made. Methods: A survey on knowledge and attitude was created and modified according to Lee's and Kim's test tool. In total, 149 students' data were collected and compared with previous studies. Results: Knowledge of ADR was relatively low (54%) but attitude was relatively high (75%). Clinical experience was important in knowledge and attitude. Knowledge and attitude showed a positive correlation. Conclusion: Increased knowledge of ADR leads to a more active attitude towards it. Hence, modification of the education system to provide a more personalized education is required.

• International journal of advanced smart convergence
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• v.10 no.4
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• pp.206-214
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• 2021

The purpose of this study is to identify the level of polypharmacy use, drug knowledge, and drug misuse behavior in the elderly, and to understand the correlation between them and their effect on drug misuse behavior. The study design was a descriptive survey study, and the participants of the study were 215 elderly people from the local community center. The research tool used drug knowledge, drug misuse behavior, and the data collection period was from February 8 to 19, 2021. The data analysis were descriptive statistics, t-test, one-way ANOVA, Pearson's correlation coefficient, and regression analysis. As a result of the study, a significant correlation variable for the drug knowledge of the elderly showed a significant correlation with prescription and non-prescription, r=.145 (p<0.05), and r=.-. 136, which showed a negative significant correlation (p<0.05). As for the significant correlation variable in the drug misuse behavior of the elderly, when prescription and non-prescription were combined, there was a significant correlation with r=.256 (p<0.01), and when not using drugs, r=.-.225 was negative. showed a significant correlation (p<0.01). In terms of the effect on drug misuse behavior, chronic disease =.145, prescription and non-prescription use = .233, which had a positive effect, and non-prescription = -.328, indicating a negative and significant effect. The provision of education on the safe use of drugs by the elderly should first be provided in the community. In addition, we need systematic education and social support for the transmission of correct knowledge on multi-drug use by the elderly and for health management.

• Genomics & Informatics
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• v.17 no.2
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• pp.18.1-18.10
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• 2019

Prediction of the relations among drug and other molecular or social entities is the main knowledge discovery pattern for the purpose of drug-related knowledge discovery. Computational approaches have combined the information from different sources and levels for drug-related knowledge discovery, which provides a sophisticated comprehension of the relationship among drugs, targets, diseases, and targeted genes, at the molecular level, or relationships among drugs, usage, side effect, safety, and user preference, at a social level. In this research, previous work from the BioNLP community and matrix or matrix decomposition was reviewed, compared, and concluded, and eventually, the BioNLP open-shared task was introduced as a promising case study representing this area.

• Journal of Korean Academy of Nursing
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• v.34 no.3
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• pp.421-429
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• 2004

Purpose: This study is to evaluate the effects of drug abuse prevention program for elementary school students. Method: The design of this study is nonequivalent control group pretest-posttest design. The subjects of experimental group were 27 students and the subjects of control group were 25 students in fifth grade of elementary school in C City, Gyeongsangbuk-do. The experimental group had Drug Abuse Prevention Program, which was two days per week program, for 5 weeks. And post-test was carried out in the same way as the pre-test. Data analysis was done using frequency, percentage, mean, standard deviation, Chi-square test, t-test, Paired Samples t-test using with SPSS WIN 11.0. Result: the experimental group, to which drug abuse prevention program was given, was improved in knowledge of drug and unacceptable attitude of drug compared to the control group, but there were no significant differences of self-esteem and assertiveness between two groups. Conclusion: The drug abuse prevention program was effective to increase knowledge and attitude of drug in elementary school students.

• The Journal of Korean Academic Society of Nursing Education
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• v.6 no.2
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• pp.376-389
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• 2000

The Purpose of this study was to grasp the status of drug uses in college students, and to investigate the knowledge and attitude when they use it. We collected through questionnaires from Sep. 1 to Oct. 30 in 1999. The subjects were 490 college students in Seoul and northern of the Kyunggi-do. The data analysis was performed using SPSS (version 7.0) and ANOVA. The results of this study were as follows. 1. There was no correlation for all factors in the relationship between general characteristics of subjects and knowledge for drugs. On the contrary, in the relation of the general characteristics and attitude for drug of subjects, some factors are statistically significant e.g., department (F=3.049, p<.010), satisfaction for school life (F=6.167,p<.002), body shape(F=8.092, p<.000), and the relationship with ones parents (F=3.728, p<.005). 2. In the analysis of drug use status and knowledge, only in the factor of administration control was statistically significant(F=4.304, p<.014) and in the relation of attitude for drug uses, drug administration was statistically significant (F=4.521, p<.004). 3. In the mean scores for the drug knowledge analysis, the highest factor was 'A narcotic make deformed persons through poisoning of physical and mental' (M=4.14), the lowest factor was 'If catch the flu during the pregnancy, should be take drug as possible as quickly to reduce negative effect for fetal' (M=1.94). 4. In the analysis for drug attitude, the highest factor was 'A drug is alike a poison' (M=3.48), 'Should be keep the usage and dosage of drug' was the lowest (M=1.48). 5. From the investigation for status of drug use, it was revealed that the most subjects (73.6%) were purchase drugs after explain their symptoms to pharmacist. And they take drugs only when they felt painful in 43.1%. The most students (70.4%) were experienced control of drug administration. It was inquired that subjects were mainly obtained information about drugs from pharmacist and television (or radio) advertisement, 33.5% and 33.1%, respectively. In the examination for existence of long-term administrators in their family, 'none' and 'only parents' are 49.6% and 37.3%, respectively. When their parents have illness, the persons go to drugstore and hospital for heath-care, 47.8% and 44.3%, respectively. On the basis of results of this study, we suggest as follows. 1. This study was analyzed data from questionnaires for college students in a part of local areas, so we suggest that the next research should be perform for national-wide students as subjects to generalize the results. 2. It is need more intensive research methodologies such as interview and observation. 3. Additional research is required for knowledge and behaviors of drug uses that will how impact on ones health behavior.

• Korean Journal of Adult Nursing
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• v.23 no.6
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• pp.554-563
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• 2011

Purpose: The purpose of this study was to investigate factors associated with drug misuse behaviors among polypharmacy elderly. Methods: This was a cross-sectional survey. Participants consisted of 116 polypharmacy elderly who were taking 5 or more medications each day. Data were collected via face to face interviews. Data were analyzed using the PASW 18.0 program. Data concerning predisposing factor (knowledge, benefit), enabling factor (communication with health care provider), and need factor (perceived health status, number of disease) were collected. Results: The total mean score of drug misuse behaviors among polypharmacy elderly was 3.04 out of 10 points. Communication with health care provider, perceived health status, and knowledge were found to be significantly correlated with drug misuse behaviors. In stepwise multiple regression analysis, a total of 42% of the variance in drug misuse behaviors was accounted for communication with health care provider, perceived health status, and knowledge. Conclusion: Therefore, education program for improving communication with health care provider, and knowledge should be designed and provided for polypharmacy elderly.

• Journal of Korean Academy of Nursing Administration
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• v.22 no.1
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• pp.91-98
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• 2016

Purpose: The aim of this study was to identify the relationship between nurses' knowledge of adverse drug reactions (ADR), attitudes, and monitoring practices and to establish an effective ADR reporting system and provide baseline data for its activation. Methods: The participants in this study were chosen by convenience sampling and included 182 nurses working at major general hospitals that operate a Regional Drug Safety Center. Data were collected from June 1 to 12, 2015 and analyzed using Cronbach's ${\alpha}$, descriptive statistics, independent t-test, one way ANOVA, Pearson correlation coefficient and stepwise regression with the SPSS program. Results: The nurses' average score for knowledge was 7.62 points, for attitude, 41.04 points and for monitoring practices, 34.22 points. ADR monitoring practices positively correlated with knowledge (r=.19, p=.011), attitude (r=.41, p<.001), drug performance competency (r=.54, p<.001), and drug education satisfaction (r=.54, p<.001). Drug performance competency, drug education satisfaction, and attitudes explained 42.0% of the ADR monitoring practices (Adj $R^2=.42$, F=43.95, p<.001). Conclusion: In order to facilitate and encourage nurses' voluntary monitoring practice of ADR, efforts must be made to create positive attitudes toward ADR, and to increase drug performance competency and drug education satisfaction.

• Journal of the Korean Society of School Health
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• v.19 no.2
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• pp.89-104
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• 2006

Purpose： This study was to develop and verify the effects of drug misuse and abuse preventive program for middle school students. Methods：This research was a quasi experimental study under the nonequivalent control group with pretest-post test design which tried to protect children from the detrimental effect of drugs and develop a drug abuse prevention program for middle school students. Data was collected from October 10th to 21th, 2005. Subject consisted of 145 middle school students in Kyeonggi, experimental group-72, control group-73. Dick & Carey's(1996) educational system was applied, based on documents and materials online related to drug abuse in order to develop drug abuse prevention program. It's composed of 4 parts, 45 minute each. The evaluation instrument testing for the knowledge about drugs was a criterion of referenced test items modeled by Dick & Carey. The instrument for attitudes about drugs was modeled by Kim, Soyaja. A pre-test was taken on the knowledge and attitudes to drugs. The experimental students were given four sessions of drug abuse prevention education. A post-test similar to the pre-test questionnaire was given in 1 week, 4 weeks following the last session. Collected data was analyzed by using SAS 9.1 program. Results：Followings are the summarized result of study 1. The experimental group, that attended the drug abuse prevention program will have more knowledgable about drugs than the control group (F=27.31, p<.0001). 2. The experimental group, that attended the drug abuse prevention program displayed greater negativism attitude than the control group (F=0.58, p=0.4477). Conclusion：The results conclude that drug abuse prevention programs increase the knowledge of middle school students but doesn't change their attitude toward drugs. Therefore we need to offer them more systematic education to increase their knowledge so it will also improve their attitudes as well.

• Journal of Korean Clinical Nursing Research
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• v.20 no.1
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• pp.53-63
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• 2014

Purpose: This study was conducted to investigate the relationship between drug-related knowledge, sick role behavior and quality of life of patients on wafarin therapy in an outpatient unit. Methods: The participants were 122 patients. Data were collected using a questionnaire and analyzed using t-test, ANOVA and Pearson correlation. Results: The Duration of wafarin averaged $28.80{\pm}32.99$ months, and 78.7% of participants remembered their blood coagulation value. The mean score for drug-related knowledge was 11.32 points out of a possible 13 points. Sick role behavior of the patients showed a moderate value with a mean of 49.83 points out of 68 points. The mean score for quality of life was rather low at 104.43 out of 175. Drug-related knowledge was significantly correlated to sick role behavior (r=0.39, p<.001), but the relationship between sick role behavior and quality of life was not significant. Also drug-related knowledge was not significantly correlated with quality of life. Conclusion: The resultsindicate that there is a need to enhance the level of drug-related knowledge in order to increase positive behavior as part of the sick role of these patients and thus improve quality of life.