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A Database Security System for Detailed Access Control and Safe Data Management (상세 접근 통제와 안전한 데이터 관리를 위한 데이터베이스 보안 시스템)

  • Cho, Eun-Ae;Moon, Chang-Joo;Park, Dae-Ha;Hong, Sung-Jin;Baik, Doo-Kwon
    • Journal of KIISE:Databases
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    • v.36 no.5
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    • pp.352-365
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    • 2009
  • Recently, data access control policies have not been applied for authorized or unauthorized persons properly and information leakage incidents have occurred due to database security vulnerabilities. In the traditional database access control methods, administrators grant permissions for accessing database objects to users. However, these methods couldn't be applied for diverse access control policies to the database. In addition, another database security method which uses data encryption is difficult to utilize data indexing. Thus, this paper proposes an enhanced database access control system via a packet analysis method between client and database server in network to apply diverse security policies. The proposed security system can be applied the applications with access control policies related to specific factors such as date, time, SQL string, the number of result data and etc. And it also assures integrity via a public key certificate and MAC (Message Authentication Code) to prevent modification of user information and query sentences.

A Study on the Accident Case and Analysis on the Actual Condition of Construction Machinery in Railroad Construction Sites (철도건설현장 건설기계 재해사례 및 실태분석에 관한 연구)

  • Son, Du-Hyun;Song, Do-Heom;Go, Seong-Seok
    • Journal of the Korean Society of Safety
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    • v.30 no.5
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    • pp.20-28
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    • 2015
  • Recently, railroad's preference greatly increased as the environment-friendly means of transportation as the importance in the aspects of environment and energy efficiency. So the government established the Korea Rail Network Authority which takes full charge of railroad construction in 20047 for regular railroad construction to combine major key points in the whole country with each other to be one city region by connecting them to each other to be within the commute time range of a hour and thirty minutes. And it has arranged large-scale railroad construction by establishing plans to build the 1st and 2nd national railroad networks as the national project and investing about 100 trillion won in it from 2006 to 2020. As large-scale railroad construction is promoted as the national project like this, there has been a string of safety accidents in it due to the large and complex construction project. As the government strengthened the safety accident prevention plans, safety accidents have tended to decrease in 2011. However, accidents of construction machinery have found to increase. Therefore, this study tried to investigate accident cases of the Korea Rail Network Authority for the recent 5 years and analyze accidents of construction machinery to prevent them in railroad construction sites and suggest accident prevention plans due to it by conducting, investigating, and analyzing the survey of its operators and superintendents of the construction sites and drawing the problems.

Modified File Title Normalization Techniques for Copyright Protection (저작권 보호를 위한 변형된 파일 제목 정규화 기법)

  • Hwang, Chan Woong;Ha, Ji Hee;Lee, Tea Jin
    • Convergence Security Journal
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    • v.19 no.4
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    • pp.133-142
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    • 2019
  • Although torrents and P2P sites or web hard are frequently used by users simply because they can be easily downloaded freely or at low prices, domestic torrent and P2P sites or web hard are very sensitive to copyright. Techniques have been researched and applied. Among these, title and string comparison method filtering techniques that block the number of cases such as file titles or combinations of key words are blocked by changing the title and spacing. Bypass is easy through. In order to detect and block illegal works for copyright protection, a technique for normalizing modified file titles is essential. In this paper, we compared the detection rate by searching before and after normalizing the modified file title of illegal works and normalizing the file title. Before the normalization, the detection rate was 77.72%, which was unfortunate while the detection rate was 90.23% after the normalization. In the future, it is expected that better handling of nonsense terms, such as common date and quality display, will yield better results.

Multiobjective Genetic Algorithm for Design of an Bicriteria Network Topology (이중구속 통신망 설계를 위한 다목적 유전 알고리즘)

  • Kim, Dong-Il;Kwon, Key-Ho
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.39 no.4
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    • pp.10-18
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    • 2002
  • Network topology design is a multiobjective problem with various design components. The components such as cost, message delay and reliability are important to gain the best performance. Recently, Genetic Algorithms(GAs) have been widely used as an optimization method for real-world problems such as combinatorial optimization, network topology design, and so on. This paper proposed a method of Multi-objective GA for Design of the network topology which is to minimize connection cost and message delay time. A common difficulty in multiobjective optimization is the existence of an objective conflict. We used the prufer number and cluster string for encoding, parato elimination method and niche-formation method for the fitness sharing method, and reformation elitism for the prevention of pre-convergence. From the simulation, the proposed method shows that the better candidates of network architecture can be found.

Analysis of the Active Compounds and Therapeutic Mechanisms of Yijin-tang on Meniere's Disease Using Network Pharmacology(I) (네트워크 약리학을 활용한 메니에르병에 대한 이진탕(二陳湯)의 활성 성분과 치료 기전 연구(I))

  • SunKyung Jin;Hae-Jeong Nam
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.36 no.1
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    • pp.50-63
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    • 2023
  • Objectives : This study used a network pharmacology approach to explore the active compounds and therapeutic mechanisms of Yijin-tang on Meniere's disease. Methods : The active compounds of Yijin-tang were screened via the TCMSP database and their target proteins were screened via the STITCH database. The GeneCard was used to establish the Meniere's disease-related genes. The intersection targets were obtained through Venny 2.1.0. The related protein interaction network was constructed with the STRING database, and topology analysis was performed through CytoNCA. GO biological function analysis and KEGG enrichment analysis for core targets were performed through the ClueGO. Results : Network analysis identified 126 compounds in five herbal medicines of Yijin-tang. Among them, 15 compounds(naringenin, beta-sitosterol, stigmasterol, baicalein, baicalin, calycosin, dihydrocapsaicin, formononetin, glabridin, isorhamnetin, kaempferol, mairin, quercetin, sitosterol, nobiletin) were the key chemicals. The target proteins were 119, and 7 proteins(TNF, CASP9, PARP1, CCL2, CFTR, NOS2, NOS1) were linked to Meniere's disease-related genes. Core genes in this network were TNF, CASP9, and NOS2. GO/KEGG pathway analysis results indicate that these targets are primarily involved in regulating biological processes, such as excitotoxicity, oxidative stress, and apoptosis. Conclusion : Pharmacological network analysis can help to explain the applicability of Yijin-tang on Meniere's disease.

Integrative applications of network pharmacology and molecular docking: An herbal formula ameliorates H9c2 cells injury through pyroptosis

  • Zhongwen Qi;Zhipeng Yan;Yueyao Wang;Nan Ji;Xiaoya Yang;Ao Zhang;Meng Li;Fengqin Xu;Junping Zhang
    • Journal of Ginseng Research
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    • v.47 no.2
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    • pp.228-236
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    • 2023
  • Background: QiShen YiQi pills (QSYQ) is a Traditional Chinese Medicine (TCM) formula, which has a significant effect on the treatment of patients with myocardial infarction (MI) in clinical practice. However, the molecular mechanism of QSYQ regulation pyroptosis after MI is still not fully known. Hence, this study was designed to reveal the mechanism of the active ingredient in QSYQ. Methods: Integrated approach of network pharmacology and molecular docking, were conducted to screen active components and corresponding common target genes of QSYQ in intervening pyroptosis after MI. Subsequently, STRING and Cytoscape were applied to construct a PPI network, and obtain candidate active compounds. Molecular docking was performed to verify the binding ability of candidate components to pyroptosis proteins and oxygen-glucose deprivation (OGD) induced cardiomyocytes injuries were applied to explore the protective effect and mechanism of the candidate drug. Results: Two drug-likeness compounds were preliminarily selected, and the binding capacity between Ginsenoside Rh2 (Rh2) and key target High Mobility Group Box 1 (HMGB1)was validated in the form of hydrogen bonding. 2 μM Rh2 prevented OGD-induced H9c2 death and reduced IL-18 and IL-1β levels, possibly by decreasing the activation of the NLRP3 inflammasome, inhibiting the expression of p12-caspase1, and attenuating the level of pyroptosis executive protein GSDMD-N. Conclusions: We propose that Rh2 of QSYQ can protect myocardial cells partially by ameliorating pyroptosis, which seems to have a new insight regarding the therapeutic potential for MI.

The Method for Real-time Complex Event Detection of Unstructured Big data (비정형 빅데이터의 실시간 복합 이벤트 탐지를 위한 기법)

  • Lee, Jun Heui;Baek, Sung Ha;Lee, Soon Jo;Bae, Hae Young
    • Spatial Information Research
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    • v.20 no.5
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    • pp.99-109
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    • 2012
  • Recently, due to the growth of social media and spread of smart-phone, the amount of data has considerably increased by full use of SNS (Social Network Service). According to it, the Big Data concept is come up and many researchers are seeking solutions to make the best use of big data. To maximize the creative value of the big data held by many companies, it is required to combine them with existing data. The physical and theoretical storage structures of data sources are so different that a system which can integrate and manage them is needed. In order to process big data, MapReduce is developed as a system which has advantages over processing data fast by distributed processing. However, it is difficult to construct and store a system for all key words. Due to the process of storage and search, it is to some extent difficult to do real-time processing. And it makes extra expenses to process complex event without structure of processing different data. In order to solve this problem, the existing Complex Event Processing System is supposed to be used. When it comes to complex event processing system, it gets data from different sources and combines them with each other to make it possible to do complex event processing that is useful for real-time processing specially in stream data. Nevertheless, unstructured data based on text of SNS and internet articles is managed as text type and there is a need to compare strings every time the query processing should be done. And it results in poor performance. Therefore, we try to make it possible to manage unstructured data and do query process fast in complex event processing system. And we extend the data complex function for giving theoretical schema of string. It is completed by changing the string key word into integer type with filtering which uses keyword set. In addition, by using the Complex Event Processing System and processing stream data at real-time of in-memory, we try to reduce the time of reading the query processing after it is stored in the disk.

Systemic Approaches Identify a Garlic-Derived Chemical, Z-ajoene, as a Glioblastoma Multiforme Cancer Stem Cell-Specific Targeting Agent

  • Jung, Yuchae;Park, Heejoo;Zhao, Hui-Yuan;Jeon, Raok;Ryu, Jae-Ha;Kim, Woo-Young
    • Molecules and Cells
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    • v.37 no.7
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    • pp.547-553
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    • 2014
  • Glioblastoma multiforme (GBM) is one of the most common brain malignancies and has a very poor prognosis. Recent evidence suggests that the presence of cancer stem cells (CSC) in GBM and the rare CSC subpopulation that is resistant to chemotherapy may be responsible for the treatment failure and unfavorable prognosis of GBM. A garlic-derived compound, Z-ajoene, has shown a range of biological activities, including anti-proliferative effects on several cancers. Here, we demonstrated for the first time that Z-ajoene specifically inhibits the growth of the GBM CSC population. CSC sphere-forming inhibition was achieved at a concentration that did not exhibit a cytotoxic effect in regular cell culture conditions. The specificity of this inhibitory effect on the CSC population was confirmed by detecting CSC cell surface marker CD133 expression and biochemical marker ALDH activity. In addition, stem cell-related mRNA profiling and real-time PCR revealed the differential expression of CSC-specific genes, including Notch, Wnt, and Hedgehog, upon treatment with Z-ajoene. A proteomic approach, i.e., reverse-phase protein array (RPPA) and Western blot analysis, showed decreased SMAD4, p-AKT, 14.3.3 and FOXO3A expression. The protein interaction map (http://string-db.org/) of the identified molecules suggested that the AKT, ERK/p38 and $TGF{\beta}$ signaling pathways are key mediators of Z-ajoene's action, which affects the transcriptional network that includes FOXO3A. These biological and bioinformatic analyses collectively demonstrate that Z-ajoene is a potential candidate for the treatment of GBM by specifically targeting GBM CSCs. We also show how this systemic approach strengthens the identification of new therapeutic agents that target CSCs.

A Study on Knowledge Entity Extraction Method for Individual Stocks Based on Neural Tensor Network (뉴럴 텐서 네트워크 기반 주식 개별종목 지식개체명 추출 방법에 관한 연구)

  • Yang, Yunseok;Lee, Hyun Jun;Oh, Kyong Joo
    • Journal of Intelligence and Information Systems
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    • v.25 no.2
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    • pp.25-38
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    • 2019
  • Selecting high-quality information that meets the interests and needs of users among the overflowing contents is becoming more important as the generation continues. In the flood of information, efforts to reflect the intention of the user in the search result better are being tried, rather than recognizing the information request as a simple string. Also, large IT companies such as Google and Microsoft focus on developing knowledge-based technologies including search engines which provide users with satisfaction and convenience. Especially, the finance is one of the fields expected to have the usefulness and potential of text data analysis because it's constantly generating new information, and the earlier the information is, the more valuable it is. Automatic knowledge extraction can be effective in areas where information flow is vast, such as financial sector, and new information continues to emerge. However, there are several practical difficulties faced by automatic knowledge extraction. First, there are difficulties in making corpus from different fields with same algorithm, and it is difficult to extract good quality triple. Second, it becomes more difficult to produce labeled text data by people if the extent and scope of knowledge increases and patterns are constantly updated. Third, performance evaluation is difficult due to the characteristics of unsupervised learning. Finally, problem definition for automatic knowledge extraction is not easy because of ambiguous conceptual characteristics of knowledge. So, in order to overcome limits described above and improve the semantic performance of stock-related information searching, this study attempts to extract the knowledge entity by using neural tensor network and evaluate the performance of them. Different from other references, the purpose of this study is to extract knowledge entity which is related to individual stock items. Various but relatively simple data processing methods are applied in the presented model to solve the problems of previous researches and to enhance the effectiveness of the model. From these processes, this study has the following three significances. First, A practical and simple automatic knowledge extraction method that can be applied. Second, the possibility of performance evaluation is presented through simple problem definition. Finally, the expressiveness of the knowledge increased by generating input data on a sentence basis without complex morphological analysis. The results of the empirical analysis and objective performance evaluation method are also presented. The empirical study to confirm the usefulness of the presented model, experts' reports about individual 30 stocks which are top 30 items based on frequency of publication from May 30, 2017 to May 21, 2018 are used. the total number of reports are 5,600, and 3,074 reports, which accounts about 55% of the total, is designated as a training set, and other 45% of reports are designated as a testing set. Before constructing the model, all reports of a training set are classified by stocks, and their entities are extracted using named entity recognition tool which is the KKMA. for each stocks, top 100 entities based on appearance frequency are selected, and become vectorized using one-hot encoding. After that, by using neural tensor network, the same number of score functions as stocks are trained. Thus, if a new entity from a testing set appears, we can try to calculate the score by putting it into every single score function, and the stock of the function with the highest score is predicted as the related item with the entity. To evaluate presented models, we confirm prediction power and determining whether the score functions are well constructed by calculating hit ratio for all reports of testing set. As a result of the empirical study, the presented model shows 69.3% hit accuracy for testing set which consists of 2,526 reports. this hit ratio is meaningfully high despite of some constraints for conducting research. Looking at the prediction performance of the model for each stocks, only 3 stocks, which are LG ELECTRONICS, KiaMtr, and Mando, show extremely low performance than average. this result maybe due to the interference effect with other similar items and generation of new knowledge. In this paper, we propose a methodology to find out key entities or their combinations which are necessary to search related information in accordance with the user's investment intention. Graph data is generated by using only the named entity recognition tool and applied to the neural tensor network without learning corpus or word vectors for the field. From the empirical test, we confirm the effectiveness of the presented model as described above. However, there also exist some limits and things to complement. Representatively, the phenomenon that the model performance is especially bad for only some stocks shows the need for further researches. Finally, through the empirical study, we confirmed that the learning method presented in this study can be used for the purpose of matching the new text information semantically with the related stocks.