• Coupled systems mechanics
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• 제12권6호
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• pp.531-537
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• 2023

Municipal solid waste landfills are unpredictable bioreactors which in cases of mishandling and bad supervision presents numerous risks. The key to municipal waste landfills is to approach them from the point of prevention of the possible consequences, which means using methods of organized waste disposal, and also utilizing landfill gas, as an unavoidable consequence with disposal of municipal solid waste with a high share of biodegradable organic matter. This paper presents an overview about problems of solid municipal waste management, type and composition of waste, and an overview of waste management condition. Further, the problem of landfill and landfill gasses is described with the calculation models of landfill production, as well as the use of the SWM GHG Calculator and LandGEM software on a specific example of gas production for the central zone at Sarajevo landfill "Smiljevici". Main focus of this thesis is the analysis of potentials of greenhouse gas emission reduction measures from the waste management. Overview of the best available techniques in waste management is presented as well as the methodology used for calculations. Scenarios of greenhouse gas emission reduction in waste management were defined so that emissions were calculated using the appropriate model. In the final section of the paper, its description of the problem of collection and utilization the landfill gas at the sanitary landfill "Smiljevici", and implementation of the system for landfill gas collection and solution suggestion for the gasification and exploitation of gas. Energy, environmental and economic benefits can be accomplished by utilizing municipal solid waste as fuel in industry and energy and moreover by utilizing energy generation from landfill gas, which this thesis emphasizes.

• 산업경영시스템학회지
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• 제46권3호
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• pp.1-6
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• 2023

In the realm of dental prosthesis fabrication, obtaining accurate impressions has historically been a challenging and inefficient process, often hindered by hygiene concerns and patient discomfort. Addressing these limitations, Company D recently introduced a cutting-edge solution by harnessing the potential of intraoral scan images to create 3D dental models. However, the complexity of these scan images, encompassing not only teeth and gums but also the palate, tongue, and other structures, posed a new set of challenges. In response, we propose a sophisticated real-time image segmentation algorithm that selectively extracts pertinent data, specifically focusing on teeth and gums, from oral scan images obtained through Company D's oral scanner for 3D model generation. A key challenge we tackled was the detection of the intricate molar regions, common in dental imaging, which we effectively addressed through intelligent data augmentation for enhanced training. By placing significant emphasis on both accuracy and speed, critical factors for real-time intraoral scanning, our proposed algorithm demonstrated exceptional performance, boasting an impressive accuracy rate of 0.91 and an unrivaled FPS of 92.4. Compared to existing algorithms, our solution exhibited superior outcomes when integrated into Company D's oral scanner. This algorithm is scheduled for deployment and commercialization within Company D's intraoral scanner.

• 한방비만학회지
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• 제23권2호
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• pp.69-77
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• 2023

Objectives: Atriplex gmelinii C. A. Meyer is a halophyte belonging to the Chenopodiaceae family, and its young leaves and stems are used as fodder for livestock. The aim of the present study was to investigate the effects of A. gmelinii extract and its solvent fractions on lipid accumulation during adipogenesis of 3T3-L1 preadipocytes. Methods: The samples of A. gmelinii were separately extracted using methylene chloride and methanol. Subsequently, they were combined to formulate the initial extract, which was then partitioned based on polarity to prepare solvent fractions. Oil Red O staining was employed to measure lipid accumulation during the differentiation of 3T3-L1 preadipocytes. To verify cytotoxicity in 3T3-L1 cells, MTT assays were conducted. The expression levels of transcription factors in 3T3-L1 preadipocytes were measured through Western blotting analysis. Results: At 50 ㎍/mL, treatment of A. gmelinii extract and its solvent fractions during the differentiation of 3T3-L1 preadipocytes significantly diminished lipid accumulation with no noteworthy cytotoxicity on cell viability. Additionally, when investigating the biochemical pathways that underlie the prevention of lipid accumulation using solvent fractions, it was found that the n-BuOH and n-hexane fractions significantly decreased the expression of key transcription factors involved in the generation of fat, such as peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding protein α (C/EBPα), and sterol regulatory element-binding protein-1c (SREBP1c). Conclusions: These findings indicate that A. gmelinii can effectively reduce the accumulation of fat in 3T3-L1 adipocytes, making it a potentially valuable material for mitigating and preventing obesity.

• 한국의상디자인학회지
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• 제25권4호
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• pp.77-92
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• 2023

The purpose of this study is to investigate the public perception of Gorpcore through Big Aata analytics. The study was conducted based on the collection of Big Data on the word 'Gorpcore' through Textom from July 24, 2017 to March 31, 2023. As a result, 63,386 words were collected from a total of 18,879 posts, and the top 50 words were determined based on frequency of appearance. Based on the collected words, centrality measures and CONCOR algorithm were performed in Ucinet 6. The research results are as follows. 1) The frequency of appearance was high in the order of 'Gorpcore look', 'fashion', 'coordination', 'clothes', 'outdoor', 'Musinsa', 'look', 'trend', 'brand' and 'ahjussi (middle-aged old man in Korean)'. These words had high TF-IDF scores, which leads to the conclusion that these are key words that are recognized as important. 2) Network centrality shows that 'Gorpcore look', 'fashion', 'outdoor', 'coordination', 'clothes', 'trend', 'look' and 'style' have a high correlation with other words. Through this, it was found that the public thinks it is important to create a variety of fashions by styling high-performance outdoor wear and casual wear, and that they are highly interested in clothes and in brands leading the Gorpcore trend. 3) As a result of the CONCOR algorithm, four significant groups were formed. The words that appear in each group are as follows. Group 1 - 'outdoor', 'Gorp', 'Normcore', 'hiking', 'functionality', 'new', 'sports', 'casual wear', 'activity', 'generation', 'collaboration'. Group 2 - 'fashion', 'trend', 'look', 'brand', 'style', 'shoes', 'ugly', 'item', 'trend', 'product', 'Salomon', 'padded jacket', 'stylishness', 'utilization', 'Winter', 'street', 'design', 'retro', 'popular', 'styling'. Group 3 - 'Gorpcore look', 'coordination', 'Musinsa', 'windbreaker', 'recommendation', 'Arcteryx', 'pants', 'man'. Group 4 - 'clothes' 'ahjussi', 'jacket', 'launching', 'spring', 'The North Face', 'collection', 'utility', 'jumper'. As a result, it can be seen that the Gorpcore is also regarded as a part of outdoor, fashion, coordination, and casual wear.

• BMB Reports
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• 제57권2호
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• pp.79-85
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• 2024

Pre-harvest sprouting is a critical phenomenon involving germination of seeds in the mother plant before harvest under relative humid conditions and reduced dormancy. In this paper, we generated HDR mutant lines with one region SNP (C/T) and an insertion of 6 bp (GGT/GGTGGCGGC) in OsERF1 genes for pre-harvest sprouting (PHS) resistance using CRISPR/Cas9 and a geminiviral replicon system. The incidence of HDR was 2.6% in transformed calli. T₁ seeds were harvested from 12 HDR-induced calli and named ERF1-hdr line. Molecular stability, key agronomic properties, physiological properties, and biochemical properties of target genes in the ERF1-hdr line were investigated for three years. The ERF1-hdr line showed significantly enhanced seed dormancy and pre-harvest sprouting resistance. qRT-PCR analysis suggested that enhanced ABA signaling resulted in a stronger phenotype of PHS resistance. These results indicate that efficient HDR can be achieved through SNP/InDel replacement using a single and modular configuration applicable to different rice targets and other crops. This work demonstrates the potential to replace all genes with elite alleles within one generation and greatly expands our ability to improve agriculturally important traits.

• 문화기술의 융합
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• 제10권3호
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• pp.713-722
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• 2024

본 연구는 인공지능(AI) 기술의 발전이 저널리즘 분야에 가져온 혁신과 변화를 조명하고, 이로 인해 발생하는 주요 윤리적 쟁점들을 검토하여, 저널리즘 분야에서 AI의 활용성을 논의한다. 블룸버그, 가디언, 월스트리트저널(WSJ), 워싱턴포스트(WP), 뉴욕타임즈(NYT) 등 전 세계 언론 및 방송사들은 취재 데이터 분석, 기사문장 생성, 뉴스제작에 이르기까지 다양한 방면에서 AI를 적극 활용 중이다. 이에 본 논문은 국내외 주요 미디어AI 서비스 유형과 특징을 속도와 규모, 다양성, 가치향상, 정확성 측면에서 종합적으로 분석하여 AI 저널리즘의 영향력과 발전 가능성을 평가한다. 나아가 균형 잡힌 시각을 유지하며 AI 도입의 기술적, 경영적, 법적 주요 쟁점들을 파악하고, 알고리즘 편향과 필터버블 등 첨단기술의 발전이 저널리즘 영역에 가져오는 도전을 체계적으로 준비하고자 한다. 마지막으로 AI와 미디어 산업의 상호지향적인 발전 방향을 모색하기 위해 사회적 합의를 통한 전향적 AI리터러시 원칙과 윤리적 가이드라인 개선의 필요성을 제언하며, 저널리즘의 본질적 가치와 임무를 조망한다.

• Tuberculosis and Respiratory Diseases
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• 제87권1호
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• pp.52-64
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• 2024

Chronic respiratory diseases such as idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and respiratory infections injure the alveoli; the damage evoked is mostly irreversible and occasionally leads to death. Achieving a detailed understanding of the pathogenesis of these fatal respiratory diseases has been hampered by limited access to human alveolar tissue and the differences between mice and humans. Thus, the development of human alveolar organoid (AO) models that mimic in vivo physiology and pathophysiology has gained tremendous attention over the last decade. In recent years, human pluripotent stem cells (hPSCs) have been successfully employed to generate several types of organoids representing different respiratory compartments, including alveolar regions. However, despite continued advances in three-dimensional culture techniques and single-cell genomics, there is still a profound need to improve the cellular heterogeneity and maturity of AOs to recapitulate the key histological and functional features of in vivo alveolar tissue. In particular, the incorporation of immune cells such as macrophages into hPSC-AO systems is crucial for disease modeling and subsequent drug screening. In this review, we summarize current methods for differentiating alveolar epithelial cells from hPSCs followed by AO generation and their applications in disease modeling, drug testing, and toxicity evaluation. In addition, we review how current hPSC-AOs closely resemble in vivo alveoli in terms of phenotype, cellular heterogeneity, and maturity.

• Geomechanics and Engineering
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• 제37권6호
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• pp.577-590
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• 2024

With increasing demand for nuclear power generation, nuclear structures are being planned and constructed worldwide. A grave safety concern is that these structures are sensitive to large-magnitude shaking, e.g., during earthquakes. Seismic response analysis, which requires P- and S-wave velocities, is a key element in nuclear structure design. Accordingly, it is important to determine the P- and S-wave velocities in the Gyeongju and Pohang regions of South Korea, which are home to nuclear power plants and have a history of seismic activity. P- and S-wave velocities can be obtained indirectly through a correlation with physical properties (e.g., N values, Young's modulus, and uniaxial compressive strength), and researchers worldwide have proposed regression equations. However, the Gyeongju and Pohang regions of Korea have not been considered in previous studies. Therefore, a database was constructed for these regions. The database includes physical properties such as N values and P- and S-wave velocities of the soil layer, as well as the uniaxial compressive strength, Young's modulus, and P- and S-wave velocities of the bedrock layer. Using the constructed database, the geological characteristics and distribution of physical properties of the study region were analyzed. Furthermore, models for predicting P- and S-wave velocities were developed for soil and bedrock layers in the Gyeongju and Pohang regions. In particular, the model for predicting the S-wave velocity for the soil layers was compared with models from previous studies, and the results indicated its effectiveness in predicting the S-wave velocity for the soil layers in the Gyeongju and Pohang regions using the N values. The proposed models for predicting P- and S-wave velocities will contribute to predicting the damage caused by earthquakes.

• 한국과학교육학회지
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• 제44권1호
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• pp.11-27
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• 2024

본 연구는 학생들의 생산적인 과학 참여에 영향을 미치는 과학공감의 역할을 조사하고, 해당 과정에서 나타나는 과학공감의 주요 요소를 분석하는 것을 목표로 하였다. 초등학교 5학년 학생 12명이 본 연구에 참여하였고, 일반공감 능력을 기준으로 세 집단으로 나누어 디자인적 사고 과정을 적용한 생산적 과학 참여 수업을 진행하였다. 문제 해결의 다섯 단계 중 아이디어 생성과 프로토타입에서 소집단의 발화를 분석하여 과학공감과 과학실천 측면에서 관찰하였다. 분석결과, 디자인적 사고 과정을 효과적으로 적용한 과학 공감은 학생들의 생산적 과학 참여를 촉진하는 것으로 나타났다. 이에 세 집단의 과학공감 및 과학실천의 평균 발화 빈도가 아이디어 생성 단계에서는 증가한 후 감소하는 경향이 나타났으며, 프로토타입 단계에서는 후반부에 오히려 발화 빈도가 증가했다. 그러나 일반공감 능력이 낮은 소집단은 프로토타입 단계에서 협력적 의사소통의 결여로 과학공감과 과학실천의 발화 빈도가 감소하는 것으로 관찰되었다. 뿐만 아니라, 학습자들은 생산적인 과학 참여 상황에서 5가지 주요 과학공감 구성요소가 모두 발화로 드러났다. 높은 일반공감 능력 집단에서는 타인과의 과학공감 요소인 공감적 이해와 공감적 걱정이 높은 빈도로 나타났으나, 낮은 일반공감 능력 집단에서는 연구대상과의 과학공감 요소인 민감성, 과학적 상상, 상황적 관심이 상대적으로 더 높은 빈도로 관찰되었다. 이러한 결과는 과학 수업에서 타인뿐만 아니라 연구대상과의 과학적으로 공감하는 경험이, 일반적인 공감 능력과는 별개의 중요한 특성으로 학생들의 생산적 과학 활동을 다양한 참여를 유발하며 이를 지속하게 할 수 있음을 시사한다. 본 연구는 과학공감이 학생들의 생산적 과학 참여에 다양한 방향으로 영향을 미칠 수 있다는 가능성을 제시하여, 과학 수업에서 과학공감의 이론적 구조와 안정성에 대한 논의에 기여할 것으로 판단된다.

• 마케팅과학연구
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• 제20권1호
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• pp.35-48
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• 2010

今天, 受到成熟零售市场挑战的时装市场需要新的 "品牌发展" 典范来提高他们的竞争优势. 时装市场的一个重要议题是为满足消费者由于生活方式的变化而产生的特别需求所进行的生活方式品牌扩张. 时装品牌扩张到生活方式产品类别, Y世代和婴儿潮可以说是新兴的 "前景"(婴儿潮的消费者正在改变他们的生活方式. Y世代正经历着他们生命阶段的变化). 他们有购买新产品的需求. 因此, 服装公司为品牌扩张注重消费群从而在新的产品类别中建立和管理他们的品牌资产是乐观的. 本文的研究目的是(a)评估母品牌和子品牌的品牌资产. (b)鉴定消费者对品牌扩张的感知营销因素. (c)评估两个选择的群体(Y世代和婴儿潮)的营销因素和扩张到生活方式的产品类别(包括家居时尚产品)品牌的品牌资产之间因果关系的结构方程模型. 关于理论框架, 本文关注传统的营销4P组合来鉴定哪个营销因素在品牌扩张资产方面更重要. 比较营销可以建立 "品牌扩张资产", 从而成功的进入新类别. 借鉴相关的文献, 通过关注选择的消费者(Y世代, 婴儿潮), 本研究发展的研究假设结合了品牌资产因子和营销因素. 在品牌扩张至生活方式产品的背景下, 品牌资产的构念包括品牌认知/联合, 品牌感知(例如感知质量, 情感价值)和从CBBE因子(Keller, 2001)中而来的品牌共鸣. 据推测, 通过品牌扩张至生活方式产品, 市场营销要素在品牌认知/联合, 品牌感知方面创建品牌扩张资产, 进而影响品牌的共鸣. 为了收集数据, 样本由韩国Y世代的女性消费者和在婴儿潮中出生的消费者. 这些在婴儿潮中出生的消费者由于生活周期的改变而对生活方式产品有较高的需求. 在韩国Y世代(n=326)和婴儿潮(n=325)的女性消费者中共有651份有用的问卷被使用. 我们用LISREL8.8测试了使用相关矩阵的结构和测量模型. 结果显示品牌扩张的感知营销因素包括三个因子: 价格/店铺形象, 产品和广告. 在Y世代的模型中, 价格/店铺形象对品牌资产因素有积极的影响(例如品牌认知/联合, 感知质量). 同时, 在品牌扩张中产品对情感价值有积极的影响. 品牌认知/联合有可能提高感知质量和情感价值, 从而对扩张至生活方式产积极的品牌产生品牌共鸣. 在婴儿潮消费者模型中, 价格/店铺形象对感知质量有积极的影响, 感知质量可以创造品牌扩张的品牌共鸣. 产品对质量感知和情感价值有正的影响, 这些都会消费者产生对扩张至生活方式产品的品牌的品牌共鸣. 但是, 在这两个群体中广告和品牌资产都是负相关. 本研究为时装营销者提供了发展成功的品牌扩张战略以及可持续的竞争优势的见解. 本研究补充和扩展了先前的有关通过营销努力的因素促使品牌扩张成功的研究. 研究结果支持为进入新的产品类别, 时装品牌扩张(Aaker and Keller, 1990; Tauber, 1998; Shine et al., 2007; Pitta and Katsanis, 1995)和营销行动的增效作用. 因此, 我们推荐营销者同时针对Y世代和婴儿潮一代通过标准化的营销推广进入新产品类别(例如家具)可以降低营销成本. 时装营销者可以(a)提供高价的产品线. (b)在韩国通过零售渠道(例如专门百货商店)强调高档特征的商店形象定位. (c)结合服装与生活方式产品包括新颖的款式和设计师的限量版. 对品牌资产,成功品牌延伸的关键是消费者的品牌认知度和品牌联合,确保新产品类别的品牌特征. 对于营销者来说, 在进入新产品类别的时候知道什么有助于更具体的联合是必要的. 对时装品牌而言, 品牌扩张的第二个关键是进入 "奢侈" 生活方式新产品类别的途径. 更高的价格或店铺形象都对质量感知有影响. 而质量感知可以引起品牌共鸣. 更重要的是, 本研究提高了对品牌扩张的理论理解并对营销者提出了在制定针对Y世代和婴儿潮一代消费者的行销项目时的方向.