• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.24 no.1
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• pp.39-46
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• 1994

The purpose of this study was to evaluate the prevalence and distribution according to the types of tooth shape anomalies in permanent teeth of 6,082 persons by means of analysis of the full mouth periapical radiographs. And the following results were obtained ; 1. Among tooth shape anomalies, the highest incidence was observed on dilaceration (20.14%), foll owed by dens invaginatus(3.02%), peg lateralis(1.48%), taurodontism (0.34%), dens evaginatus (0.33%), talon cusp(0.20%), fusion(0.07%) and gemination(0%) in descending order of frequency. 2. Peg lateralis, dens invaginatus and dilaceration occurred more prevalent in females, and other types of tooth shape anomalies occurred more prevalent in males. 3. Dens evaginatus and taurodontism occurred with bilateral tendency, but other anomalies occur- ed with unilateral tendency. 4. As to the involved teeth, maxillary lateral incisors were the most frequently involved teeth on peg lateralis, dens invaginatus and talon cusp. And the mandibular premolars were the most frequently involved teeth on dens evaginatus, the maxillary first molars were on taurodontism, the maxillary second premolars were on dilaceration, and the mandibular incisors and canines were on fusion.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.27 no.1
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• pp.243-249
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• 1997

Adenoid cystic carcinoma is a malignant salivary gland tumor with typical histologic patterns. The majority of these tumors occurs in the minor salivary glands. especially mucosa of the hard palate. The authors experienced the patients, who complained the tumor-like soft tissue masses on the palatal and mouth floor area. After careful analysis of clinical, radiological and histopathological findings, we diagnosed them as adenoid cystic carcinomas in the minor salivary glands, and obtained results were as follows : 1. Main clinical symptoms were a slow growing soft tissue mass with normal intact mucosa on the palatal area, and soft tissue mass with mild pain on the mouth floor area. 2. In the radiographic exarnminations, soft tissue masses were observed with invasion to adjacent structures, and moderate defined, heterogeneous soft tissue mass with enhanced margin, respectively. 3. In the histopathologic exarnminations, dark-stained, small uniform basaloid cells in the hyaline or fibrous stroma were observed as solid and cribriform patterns, respectively.

• Journal of information and communication convergence engineering
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• v.10 no.2
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• pp.210-214
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• 2012

A microtiter well plate DNA hybridization method using Mycobacterium kansasii-specific rpoB DNA probe (kanp) were evaluated for the detection of M. kansasii from culture isolates. Among the 201 isolates tested by this method, 27 strains show positive results for M. kansasii, but the other 174 isolates were negative results for M. kansasii. This result was consistent with partial rpoB sequence analysis of M. kansasii and the result of biochemical tests. The negative strains by this DNA-DNA hybridization method were identified as Mycobacterium tuberculosis (159 strains), Mycobacterium avim (5 strains), Mycobacterium intracellulare (8 strains), and Mycobacterium flavescens (2 strain) by rpoB DNA sequence analysis. Due to high sensitivity and specificity of this test result, we suggest that DNA-DNA hybridization method using rpoB DNA probes of M. kansasii could be used for the rapid and convenient detection of M. kansasii.

• Journal of information and communication convergence engineering
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• v.7 no.4
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• pp.576-579
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• 2009

Anti-HIV-1 activities for the extracts (buthanol, hexane, chloroform, and water) of medicinal plants widely used in the folk medicine were evaluated for screening of anti-AIDS agents. The activities of the extracts to inhibit HIV-1 replication were also analyzed. The 50% effective concentration (EC50) of inhibition activity of the p24 production for chloroform extract of Saphora flavescens, chloroform extract of Herba ephedrae, and hexane extract of Pachyma hoelen Rumph showed 5.8, 29.9, and 37.3 2g/ml, respectively, as good activities. Hexane extract of Sophora flavescens, buthanol extract of Tulipa edulis, hexane extracts of Tulipa edulis, Herba ephedra, and Pachyma hoelen Rumph in the 50% cytotoxic concentration ($CC_{50}$) in inhibition activities of recombinant HIV-1 RT showed 12.9, 19.5, 11.6, 12.0, and 36.8 % at concentration of 200 ${\mu}g$/ml, respectively, as good activities. From these results, chloroform extract of Saphora flavescens, chloroform extract of Herba ephedrae, and hexane extract of Pachyma hoelen Rumph were very effective against HIV-1 among all extracts tested. Therefore, we expect these plants will be a useful for anti- HIV-1 therapeutics in future.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.05a
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• pp.954-957
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• 2015

A recombinant baculovirus vector systems were composed of genes of polyhedron promoter, vesicular stomatitis virus G (VSVG), polyA, cytomegalovirus (CMV) promoter, enhanced green fluorescent protein (EGFP), and protein transduction domain (PTD). These recombinant baculovirus vector system were transfected into various cell lines and tissues and confirmed gene transfer and expression of these vector systems with only control vector system. From the result, gene transfer and gene expression of recombinant baculovirus vector systems were superior in terms of efficacy and safety than in the control vector system.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.05a
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• pp.943-946
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• 2015

For myelination, Schwann cells and neuron cells from dorsal root ganglion (DRG) of rat embryos (E16) were cultured in vitro system. The purified DRG cells with anti-mitotic agents and purified Schwann cells were cocultured and then accomplished myelination processing. Treatment of M. leprae-specific phenolic glycolipid-1 (PGL-1) into this coculture system was performed and then accomplished demyelination. Therefore, we identified demyelination processing using antibody of myelin basic protein (MBP).

• Proceedings of the Korean Information Science Society Conference
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• 2007.06b
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• pp.358-362
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• 2007

Glycomics와 Glycobiology는 Oligosaccharides와 Carbohydrate의 구조와 기능을 연구하기 위한 중요한 연구 방법이다. 현재 컴퓨터 시뮬레이션을 이용한 분자 모사 실험이 많은 연구 단체에 의해서 진행되고 있지만, 많은 컴퓨터 자원을 요구하는 문제로 인해서 활발하게 이루어 지지 않고 있는 실정이다. 현 시점에서 이러한 문제를 해결하기 위해서는 많은 자원과 오랜 시간을 소비해서 얻은 결과 데이터를 많은 과학자들에 의해서 공유하고 협업할 수 있는 시스템이 필요하다. Glyco-MGrid시스템은 분자 시뮬레이션 서비스 제공에 중점을 두고 있는 MGrid에서 생성되는 e-Clycomics 데이터들을 통합 관리하기 위한 사이버인프라스트럭쳐이다. 이 Glyco-MGrid는 분자 시뮬레이션의 결과를 통합 관리하기 위한 통합 데이터베이스 제공과 이를 통한 과학자들간의 협업을 지원하기 위해 그리드 기반의 e-Glycomics를 위한 공유, 통합 환경을 제공한다.

• Proceedings of the Korean Information Science Society Conference
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• 2007.06b
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• pp.437-440
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• 2007

최근 환경 문제를 해결하기 위하여 환경 문제의 많은 컴퓨터 기술들이 응용되고 있다. 환경 정보는 환경오염원 및 주위에 미치는 영향과 오염된 농도에 대한 정보를 연구 및 분석 할 수 있는 분야이다. 최근 환경에 관련 연구가 일부에서 수행되고 있으나 이를 IT기술과 접목하여 다양한 정보를 효율적으로 저장 및 검색 할 수 있는 시스템은 부족한 실정이다. 또한 현재 환경오염의 측정방법으로는 수작업으로 이루어지는 경우가 많아서 공간적 및 물리적 제약이 있는 따르는 실정이다. 환경오염에 관한 정보를 센서를 사용하여 사용자에게 실시간으로 효과적으로 저장 관리하여 관련된 연구자들 간에 서로가 필요한 정보를 쉽게 공유할 수 있도록 본 논문에서는 Ubiquitous Sensor Network(USN), Java Message Service(JMS) 및 Webservice를 이용한 환경 모니터링 서비스를 제안 한다. 본 논문에서 제안한 시스템은 환경정보와 사용자간에 유연성, 확장성 및 실시간을 보장해 주는 시스템을 구현한다.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.25 no.1
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• pp.133-140
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• 1995

The arteriovenous malformation, an uncommon lesion, is a direct communication between an artery and a vein that bypasses the intervening capillary bed. The authors experienced two cases of arteriovenous malformation in 17-year-old and 18-year-old female patients who had suffered from mandibular pain and gingival bleeding. As a result of careful analysis of clinical and angiographic radiological examinations, we diagnosed them as arteriovenous malformations, and the results were as follows : 1. Main clinical symptoms were dull pain and gingival bleeding on the mandibular body area, and reddness, pain on palpation, thrill and palpitation in the lesional sites were also observed. 2. Radiographically, well-defined radiolucent lesions with multiple osteolytic defects were observed. In radio-nuclide scan, increased uptakes of radioisotope were observed in the lesional sites. 3. Increased venous shunt supplied by the facial, lingual and inferior alveolar arteries was observed in angiography. After embolotherapy was performed, no recurrence was reported during 3 to 6 months follow up.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.24 no.2
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• pp.403-410
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• 1994

The purpose of this study was to investigate the irradiation effects on the secretory granules of the rat submandibular gland acinar cell. For this study, Sprague-Dawley strain rats were irradiated to their neck region with the dose of 5Gy and l0Gy by 6MV X-radiation, and sacrificed on the experimental periods after irradiation. The authors observed the ultrastructural changes of the secretory granules of the rat submandibular gland acinar cell under a trasmission electron microscope. The results were as follows: In the transmission electron microscopic examination, secretory granules were blurred in limiting membrane on the 3hours groups after irradiation. And they showed decrease in number, irregularities in shape and distributional pattern, and inhomogeneous internal electron density on the Iday and 3days groups. After then, these changes were recovered in shape and distributional pattern on the 14days groups, and changes of internal electron density and limiting membrane were recovered on the 28days groups after irradiation. Among the intracellular organelles, rough endoplasmic reticulum was scattered, but golgi complex was not changed. And such pathologic changes were earlier and more prominent in 10Gy irradiated groups than in 5Gy irradiated groups.