This study is conducted to investigate the organization of Cheongunri in Cheong-song, as well as the characteristics of folk houses. In this study, 82 folk houses, including the villages, are surveyed; among them, 15 houses are intensively analyzed in terms of the structure of plane and the arrangement of space. The focus of study is on discovering an internal order system of villages and tracing a relationship between the characteristics of houses and the environmental factors. According to the results of the study, an Intrinsic order in Cheongunri is found to be related to the mountain axis, the road system, and the flow axis; and the form of folk houses is also found to be influenced by this order. The major characteristics of folk houses can be summarized as follows: (1) Most of the houses face east along the mountain axis, whereas houses influenced by the flow axis tend to face south. (2) The side of houses tend to be open to the outside, showing external directionality. This characteristic seems to be closely related to the direction of the main gate in a house site. (3) The layout of the main quarters and the annex quarters is found to be related to the direction of the main gate in a house site. Especially, the characteristics of courtyard are found to be affected by the annex quarters. From the above results, it can be concluded that villages have an intrinsic order depending on the geographic characteristics of a surrounding natural environment, and folk houses have also changed accordingly.
The purpose of this study is to investigate the modernity characteristics of the traditional housing in Seoul 1920s to 1930s setting the criterion for analyses based on a Korean architect, Park, Kil-Ryong 'Housing improvement theory' about 'the Housing Plan of the Middle Area in Choseon'. The architect Park, Kil-Ryong expressed 'Housing Improvement Theory' positively founded on having a deep knowledge of traditional architecture. At his early working stage in 1928, he announced 'Housing Improvement Theory' about 'the Housing Plan of the Middle Area in Choseon' from the paper titled 'An Inquiry into the Housing of the Middle Area in Choseon', It is inferred that his paper quite affected the modern changes of traditional housing of those days. As the results of the study, even though the main floored room still keeps the symbolical and central position in traditional housing, the size of that is designed to be smaller than before. The room on the opposite side is generally designed widely as the scope more than 2 'KAN' and shows the features of expansion and division according to functions. By interchanging the location of the kitchen, the inner room as the main living space souths in the front of the house. The kitchen is designed as fitting size and separated from the space of working, linking, setting the table, keeping things and others. The bathroom is built in the house and then connected to the corridor. Each space is effectively planned for the best location in the house as considering lightening and ventilation.
Background: Curcumin, a phenolic compound extracted from the rhizomes of Curcuma longa, has shown cytotoxic effects against a variety of cancers. The aim of this study was to identify potential microRNA (miRNA) mediators of the anticancer effects of curcumin in ovarian cancer cells. Materials and Methods: SKOV3 ovarian cancer cells were treated with curcumin ($10-60{\mu}M$) and miR-9 expression, cell proliferation, and apoptosis were assessed. The effects of miR-9 depletion on curcumin-mediated growth suppression were also examined. Phosphorylation of Akt and forkhead box protein O1 (FOXO1) was measured in cells with miR-9 overexpression or curcumin treatment. Results: Curcumin caused a significant and dose-dependent increase of miR-9 expression in SKOV3 cells, while significantly impeding cell proliferation and stimulating apoptosis. Depletion of miR-9 significantly (p<0.05) attenuated the growth-suppressive effects of curcumin on SKOV3 cells, coupled with reduced percentages of apoptotic cells. In contrast, overexpression of miR-9 significantly enhanced the cleavage of caspase-3 and poly(ADP-ribose) polymerase and promoted apoptotic death in SKOV3 cells. Western blot analysis showed that both miR-9 overexpression and curcumin similarly caused a significant (p<0.05) decline in the phosphorylation of Akt and FOXO1, compared to untreated cells. Conclusions: The present study provided evidence that curcumin exerts its cytotoxic effects against SKOV3 ovarian cancer cells largely through upregulation of miR-9 and subsequent modulation of Akt/FOXO1 axis. Further studies are needed to identify direct targets of miR-9 that mediate the anticancer effects of curcumin in ovarian cancer cells.
Journal of Advanced Marine Engineering and Technology
/
v.41
no.4
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pp.310-315
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2017
Recently constructed ships are equipped with high efficiency propeller for low fuel consumption and comfortable operation. Based on the torsional vibration analysis of the shaft system of the high efficiency propeller, using the propeller damping method considering the characteristics of previous propeller designs, a considerable amount of analysis errors are found to be generated. These errors are expected to increase as the development of high efficiency vibration propellers continues. In this paper, errors in torsional vibration analysis, in accordance with various propeller damping methods, are reviewed. In addition, a propeller damping method suitable for use at present is suggested by reviewing the comparison results of analysis and measurement values according to the propeller damping methods for vessels adopting the high efficiency direct-coupled propeller with 10MW class.
For the purpose of improving the nursing research on the woman's health the nursing papers form Korea were analyzed by subject and content. This work was anticipated to suggest the direction of the research on the filed of woman's health. A total of 420 papers form journals, TaeHan KanHo, Journal of Academy of Nursing, and Journal of Korean Woman's Health Nursing Academic Society published from 1992 to 1996 were analyzed by Dubar and Patterson's criteria. The Number of papers on the woman's health was 66(15.7%), and those of mother's role and other clinical studies were 36(8.6%) and 318(75.7%) each. Special fields of the 66 papers on the woman's health and its number were health management 27(40.9%), psychiatric health 15(22.7%), postmenopausal period 5(7.6%), sex 5(7.6%), menstruation 4(6.1%), abortion 3(4.5%), nursing need 2(3.0%), violence 1(1.5%) respectively. Considering the subjects according to the life cycle, the subject on pregnant and middle aged period were more frequent than that on juvenile, peripartum, married or aged periods. According to above results, the proposals for promoting the nursing research were followings : Woman should be included as a subjects more frequently in general nursing research. The methodology for comparison study on the sex difference should be developed to understand the multifaced phenomena of woman's health. The factor analysis affecting the woman's health inadequately should be done.
Aloe-emodin (AE), a natural anthraquinone compound, has been reported to exhibit anticancer activity in various cancer cell lines and anti-inflammatory effects in murine macrophages. In the present study, we investigated the cancer chemopreventive effects of AE in an Apc-deficient Min mouse model. In the first experiment, male Min mice were fed a basal diet or diets containing 5 ppm AE and 10 ppm AE for 12 weeks. The dietary administration of 5 ppm AE significantly reduced the number of colorectal tumors. In a second experiment, we investigated the effects of AE on colitis-related colon carcinogenesis in Min mouse treated with dextran sodium sulfate (DSS). Female Min mice were administered 1% DSS in their drinking water for 7 days. AE was given to mice in their diet at a dose of 5 or 50 ppm for 5 weeks. Feeding with AE significantly reduced the number of colorectal tumors. When proliferation of cells in normal-appearing colonic mucosa was assessed by monoclonal anti-rat Ki-67 antibody (MIB-5) immunohistochemistry in experiments 1 and 2, the AE treatment significantly decreased the mean MIB-5-labeling index. These results suggest that the dietary administration of low-dose AE may have chemopreventive effects against development of colorectal tumors in Min mice, possibly in part by reducing cell proliferation in colorectal mucosa.
Kim, Dong-Won;Kim, Hee-Jun;Park, Jong-Suk;Kim, Dae-Hyang;Cheong, Seong-Soo;Ryu, Jeong
Korean Journal of Medicinal Crop Science
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v.18
no.2
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pp.74-78
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2010
This experiment was carried out to select suitable organic matter in To-jik nursery (self soil nursery) for complement To-jik nursery's defects that are deterioration of raw material by poor quality of seed ginseng and reduction of the quantity in seed ginseng production. Organic matter used were Yacto, rice bean, defatted rice bran, soybean cake and their mixture. As follows, bulk density in soil physical property by treating organic composts was the greatest in soybean cake and the next was followed by mix, Yacto, defatted rice bran, and rice bran treatment in order. Soil pore space ratio was totally the opposite; that was rice bran the first and followed by defatted rice bran, Yacto, mix and soybean cake treatment. The incidence rate of damping off by treating organic composts was 1.5% in both soybean cake and mix while the others was 1.0%. Emergence time was the same among treatment on April 16 and Emergence rate was the highest at 73% in Yacto. There was no significant differences among treatment in the growth of aboveground part but it was a little better in defatted rice bran treatment. In Yacto treatment, the growth of underground part, total root number per kan, rate of first grade ginseng seedling, and rate of usable ginseng seedling etc. were entirely higher but there was little differences. Using defatted rice bran was slightly lower in productivity compared to Yacto, but the possibility was high as a alternative for Yacto in a view of managing cost down.
The composite photocatalysts of a Fe-modified carbon nanotube (CNT)-$TiO_2$ were synthesized by a two-step sol-gel method at high temperature. Its chemical composition and surface properties were investigated by BET surface area, scanning electron microscope (SEM), Transmission Electron Microscope (TEM), X-ray diffraction (XRD) and ultraviolet-visible (UV-Vis) spectroscopy. The results showed that the BET surface area was improved by modification of Fe, which was related to the adsorption capacity for each composite. Interesting thin layer aggregates of nanosized $TiO_2$ were observed from TEM images, probably stabilized by the presence of CNT, and the surface and structural characterization of the samples was carried out. The XRD results showed that the Fe/CNT-$TiO_2$ composites contained a mix of anatase and rutile forms of $TiO_2$ particles when the precursor is $TiOSO_4{\cdot}xH_2O$ (TOS). An excellent photocatalytic activity of Fe/CNT-$TiO_2$ was obtained for the degradation of methylene blue (MB) under visible light irradiation. It was considered that Fe cation could be doped into the matrix of $TiO_2$, which could hinder the recombination rate of the excited electrons/holes. The photocatalytic activity of the composites was also found to depend on the presence of CNT. The synergistic effects among the Fe, CNT and $TiO_2$ components were responsible for improving the visible light photocatalytic activity.
Journal of the Institute of Convergence Signal Processing
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v.14
no.3
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pp.181-190
/
2013
In this paper, we designed file system in order to utilize data analysis by using correlation result from Daejeon correlator including related software development. Correlation results are consisted of visibility component (amplitude and phase) of radio source, but for data analysis of correlation result, various information such as weather, radio telescope position, observation time, radio source position, source type, and receiver noise temperature are needed. In this paper, we designed file system as a directory-structure for making use of these informations at Linux system for analyzing data and developed software to make file system. To verify the effectiveness of designed file system and developed software, file system generation experiment is conducted, and then astronomers accepted that there is no severe problem for scientific analysis using designed file system.
In order to investigate experimentally that effect of Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture on acutely damaged liver of rats induced by radix aconiti, the author gave Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture according to method of manufacture stimulation to corresponding points, Kan-su(B18) and Ki-mun(Liv14), and carried out hematological, serological observation. Experimental groups were divided into 2 group : the one group was injected with extracted solution prepared by distillation method (A aqua-acupuncture treatment group), the other group was injected with extracted solution prepared by alchol extraction method (B aqua-acupuncture treatment group). The following results were obtained : 1. WBC level was decreased significantly in the experimental groups at 12, 24 and 48 hours as compared with the control group. RBC and hemoglobin levels were not changed significantly in the experimental groups. 2. Total cholesterol level was decreased significantly in the experimental groups at 12, 24 and 48 hours as compared with the control group. ALP level was decreased significantly in the experimental groups at 6 and 24 hours as compared with the control group. ${\gamma}-GTP$ level was decreased significantly in the experimental groups at 6, 12, 24 and 48 hours as compared with the control group. 3. GOT level was decreased significantly in the experimental groups at 6 and 12 hours as compared with the control group. GPT level was decreased siginificantly in the experimental groups at 12, 24 and 96 hours as compared with the control group. According to the above findings, it is considered that Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture has effects of recovery of acutely damaged liver.
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