• Journal of Animal Science and Technology
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• v.51 no.2
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• pp.135-142
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• 2009

The present study was undertaken to investigate the effects of slaughter weight (SW) of finishing pigs fed a low-energy diet on growth efficiency and carcass quality and thereby to assess the optimal SW. (Yorkshire $\times$ Landrace) $\times$ Duroc-crossbred gilts and barrows were fed a diet containing 3,060 kcal DE/kg from 80-kg BW and slaughtered at 110, 125, or 135 kg, after which the belly, the most preferred cut in Korea, as well as the least preferred cuts ham and loin were subjected to physicochemical and sensory analyses. Both ADG and ADFI were greater (P<0.05) in the group slaughtered at 125 or 135 kg than in the 110-kg-SW group, whereas the opposite was true for gain:feed (P<0.01). Backfat thickness (BFT), which increased with increasing SW (P<0.01 and P<0.05), was greater in barrows than in gilts (P<0.01); BFT of barrows at 125 kg (24.6 mm) was comparable to that of gilts at 135 kg (24.2 mm). Physicochemical characteristics of the belly, ham and loin were minimally affected, if not affected, by SW; of note, however, the redness of the ham increased between 110- and 125-kg SW (P<0.05). In sensory evaluation of the belly, the fat:lean balance, which is a most important quality trait in this cut, was best (P<0.05) at 125 kg of SW, but the overall acceptability of this cut was not changed by SW. In the ham and loin, the marbling score increased (P<0.01) between 110- and 125-kg SW, whereas color, aroma, off-flavor, and drip were unaffected by SW. In addition, the acceptability of the loin increased (P<0.05) between 110- and 125-kg SW. In cooked meats, none of color, aroma, off-flavor, juiciness, tenderness, taste, and acceptability was changed by SW, except for an increase (P<0.05) in darkness of loin color between 110- and 125-kg SW. In conclusion, the optimal SW for the present subpopulation on the present low-energy diet lie in between 125 and 135 kg for gilts and at 125 kg for barrows.

• Journal of Ginseng Research
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• v.41 no.3
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• pp.247-256
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• 2017

Background: KG-135, a standardized formulation enriched with Rk1, Rg3, and Rg5 ginsenosides, has been shown to inhibit various types of cancer cells; however, the underlying mechanisms are not fully understood. In this study, we explored its effects in A549 human lung cancer cells to investigate the induction of Forkhead Class box O3a (FOXO3a) and autophagy. Methods: Cell viability was determined by sulforhodamine B staining. Apoptosis and cell cycle distribution were analyzed using flow cytometry. The changes of protein levels were determined using Western blot analysis. Autophagy induction was monitored by the formation of acidic vesicular organelles stained with acridine orange. Results: KG-135 effectively arrested the cells in G1 phase with limited apoptosis. Accordingly, a decrease of cyclin-dependent kinase-4, cyclin-dependent kinase-6, cyclin D1, and phospho-retinoblastoma protein, and an increase of p27 and p18 proteins were observed. Intriguingly, KG-135 increased the tumor suppressor FOXO3a and induced the accumulation of autophagy hallmark LC3-II and acidic vesicular organelles without an increase of the upstream marker Beclin-1. Unconventionally, the autophagy adaptor protein p62 (sequestosome 1) was increased rather than decreased. Blockade of autophagy by hydroxychloroquine dramatically potentiated KG-135-induced FOXO3a and its downstream (FasL) ligand accompanied by the cleavage of caspase-8. Meanwhile, the decrease of Bcl-2 and survivin, as well as the cleavage of caspase-9, were also drastically enhanced, resulting in massive apoptosis. Conclusion: Besides arresting the cells in G1 phase, KG-135 increased FOXO3a and induced an unconventional autophagy in A549 cells. Both the KG-135-activated extrinsic FOXO3a/FasL/caspase-8 and intrinsic caspase-9 apoptotic pathways were potentiated by blockade of autophagy. Combination of KG-135 and autophagy inhibitor may be a novel strategy as an integrative treatment for cancers.

• Journal of the Korean Society of Physical Medicine
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• v.4 no.4
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• pp.275-280
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• 2009

Purpose：We have investigated to analysis biomechanics for pinch strength due to elbow flexion degree. Methods：Pinch strength was measured by Electro Dynamometer(G-100) using four elbow flexion degree ($0^{\circ}$, $45^{\circ}$, $90^{\circ}$, $135^{\circ}$). Results：In experimental results, we found that pinch strengths were 5.4kg($0^{\circ}$), 4.8kg($45^{\circ}$), 5.6kg($90^{\circ}$) and 5.2kg($135^{\circ}$), respectively. The Pinch strengths got maximum at $90^{\circ}$ degree, minimum at $45^{\circ}$ degree. We have calculated F1 values using $\sum$T=0. As a result F1 values were 540N($0^{\circ}$), 480N($45^{\circ}$), 560N($90^{\circ}$) and 520N($135^{\circ}$), respectively. F1 values got maximum at $90^{\circ}$ degree, minimum at $45^{\circ}$ degree. Data curve line of $F_1$ values was increased in 45~90 section and decreased in 0~45, 90~135 sections, respectively. Conclusion：$F_1$ (Flexor digitorum superficialis and profundus) values were 10 times bigger than pinch strengths. Data curve line of $F_1$ values was similar to active length-tension curve in 45~90, 90~135 sections.

• Asian-Australasian Journal of Animal Sciences
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• v.6 no.1
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• pp.135-138
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• 1993

Twelve intact and 12 docked Najdi lambs of equal numbers of males and females were utilized in the experiment. All lambs were raised under similar conditions until they attained 40 kg shorn and shrunk body weight. Thereafter, lambs were individually fed ad libitum on a diet formulated to contain 11.20 MJ ME/kg and slaughtered after 60 days feeding period. The results showed that Najdi rams averaged 6.14 kg more total gain (p < .05), required 6.80 kg less feed (p < .05) per kg of gain and produced 3.2 and 3.07 kg more (p < .05) carcass and salable cuts weights over the feeding period than comparable ewes. Body wall thickness and kidney and pelvic fat weight were greater (p < .05) for ewes than for rams; dressing percent, longissimus area and fat thickness were not significantly influenced by sex of lambs. Docked lambs kept for 60 days on feed required 1.80 kg less feed (p < .05) per kg of gain and produced 2.21 kg more (p < .05) salable wholesale cuts weight than intact lambs. Docking was not a significant source of variation for total gain, carcass weight, dressing percent, longissimus dorsi area, body wall thickness and fat thickness.

• Journal of Animal Science and Technology
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• v.49 no.4
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• pp.459-470
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• 2007

Domestically, finishing pigs are marketed at 110 kg on an average. However, it is thought to be feasible to increase the market weight to 120kg or greater without decreasing the carcass quality, because most domestic pigs for pork production have descended from lean-type lineages. The present study was undertaken to investigate the growth efficiency and profitability of ‘high’-market wt pigs and the physicochemical characteristics and consumers' acceptability of the high-wt carcass. A total of 96 (Yorkshire × Landrace) × Duroc-crossbred gilts and barrows were fed a finisher diet ad laibtum in 16 pens beginning from 90-kg BW, after which the animals were slaughtered at 110kg (control) or ‘high’ market wt (135 and 125kg in gilts & barrows, respectively) and their carcasses were analyzed. Average daily gain and gain:feed did not differ between the two sex or market wt groups, whereas average daily feed intake was greater in the barrow and high market wt groups than in the gilt and 110-kg market wt groups, respectively(P<0.01). Backfat thickness of the high-market wt gilts and barrows corrected for 135 and 125-kg live wt, which were 23.7 and 22.5 mm, respectively, were greater (P<0.01) than their corresponding 110-kg counterparts(19.7 & 21.1 mm). Percentages of the trimmed primal cuts per total trimmed lean (w/w), except for that of loin, differed statistically (P<0.05) between two sex or market wt groups, but their numerical differences were rather small. Crude protein content of the loin was greater in the high vs. 110-kg market group (P<0.01), but crude fat and moisture contents and other physicochemical characteristics including the color of this primal cut were not different between the two sexes or market weights. Aroma, marbling and overall acceptability scores were greater in the high vs. 110-kg market wt group in sensory evaluation for fresh loin (P<0.01); however, overall acceptabilities for cooked loin, belly and ham were not different between the two market wt groups. Marginal profits of the 135- and 125-kg high-market wt gilt and barrow relative to their corresponding 110-kg ones were approximately -35,000 and 3,500 wons per head under the current carcass grading standard and price. However, if it had not been for the upper wt limits for the A- and B-grade carcasses, marginal profits of the high market wt gilt and barrow would have amounted to 22,000 and 11,000 wons per head, respectively. In summary, 120～125-kg market pigs are likely to meet the consumers' preference better than the 110-kg ones and also bring a profit equal to or slightly greater than that of the latter even under the current carcass grading standard. Moreover, if only the upper wt limits of the A- & B-grade carcasses were removed or increased to accommodate the high-wt carcass, the optimum market weights for the gilt and barrow would fall upon their target weights of the present study, i.e. 135 and 125 kg, respectively.

• The Korea Swine Journal
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• v.26 no.1 s.293
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• pp.134-135
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• 2004

• The Korea Swine Journal
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• v.25 no.11 s.291
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• pp.134-135
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• 2003

• Magazine of the Korea Concrete Institute
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• v.4 no.3
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• pp.135-146
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• 1992

프리텐션 방식 원심력 고강도콘크리트 말뚝이 KS F4306 규격에 제정되어 콘크리트의 압축강도가 800kg/$ extrm{cm}^2$ 이상의 제조가 불가한 실정이 것으로 평가 된다. 따라서 본 연구에서는 고강도콘크리트 말뚝 제조에 적용하기 위한 고황산염 시멘트의 실험적 연구로써 석고계 첨가량 및 단위 시멘트량 변화가 증가양생 콘크리트의 제 강도 특성에 미치는 영향을 규명하는데 목적이 있다. 연구결과로부터 석고첨가량이 증대하면 콘크리트강도가 향상되지만, 7.5% 이상 첨가시에는 오히려 강도 저하현상이 나타나는 것으로 분석되었으며, 특히 단위 시멘트량 변화에 따른 압축강도 영향은 그다지 크지 않은 것으로 나타났다. 한편 최고 압축강도 발현은 석고첨가량 5~7.5% 첨가와 단위시멘트량 500~540kg/㎥ 조건에서 800kg/$\textrm{cm}^2$ 이상의 고강도 콘크리트 제조가 가능함을 확인하였다.

• Korean Journal of Ecology and Environment
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• v.39 no.2 s.116
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• pp.157-166
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• 2006

Characteristics of ichthyofauna and fish community in the Lagoon Gyeongpo, Korea, were investigated from May to October 2005. Total 26 species caught during the period were belonged to 18 families. Dominant species was T. hakonesis (50.7%) and subdominant species was A. flavimaus (25.4%). K. punctatus (11.1%), M. cephalus (6.5%), E. japonicus (1.5%), C. castaneus (1.0%) were also numerous. Total biomass of collected fish was 401.8 kg, and biomass of each species was T, hakonensis 147.0 kg, A. flavimanus 135.8 kg, K. punctatus 85.6 kg and M. cephalus 23.8 kg. Seasonal variation of fish community seems to be related to spawning periods of species. In conclusion, it appeared that the ratio of the primary freshwater species was gradually decreased, while the peripheral freshwater and seawater species were gradually increased when compared to the data obtained from the past with respect to the ichthyofauna of the Lagoon Gyeongpo.

• Advances in Traditional Medicine
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• v.9 no.2
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• pp.135-141
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• 2009

The purpose of this study was to characterize the putative anxiolytic-like effects of the 70% ethanol extract of Portulaca oleracea (EPO) using an elevated plus maze (EPM) in mice. The EPO was orally administered at 50, 100, 200 or 400 mg/kg to ICR mice, 1 h before the behavioral evaluation in the EPM, respectively. Control mice were treated with an equal volume of 10% tween 80, and positive control mice with diazepam (1 mg/kg). Single treatments of the EPO significantly increased the percentage of time spent and arm entries into the open arms of the EPM versus controls (P < 0.05). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with the saline controls. In addition, the anxiolytic-like effects of the EPO were blocked by flumazenil (10 mg/kg, i.p), a $GABA_A$ antagonist not by WAY 100635 (0.3 mg/kg, i.p), a 5-$HT_{1A}$ receptor antagonist. These results indicate that P. oleracea is an effective anxiolytic agent, and suggest that the anxiolytic-like effects of P. oleracea is mediated via the GABAergic nervous system.