• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.160-174
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• 2007

Purpose: The purpose of this study was to investigate about missed abortion pathophysiology, diagnosis, medical treatment and to research the trend of the study related to missed abortion. Methods: We referred a PubMed site by using search word of "missed abortion"(Limits: 3 Year, only items with abstracts, Human). Results: 37 journals with 49 papers were searched. Conclusion: 1. The study of missed abortion pathophysiology was the following. The first was that important pathologies such as molar pregnancy and placental trophoblastic disease can be diagnosed by routine histopathologic analysis of product of conception following first-trimester spontaneous miscarriages. The second was that coelomic fluid leptin concentration in missed abortion is higher than in normal. The third was that adenosine deaminae activity in serum and placenta of patients with anembryonic pregnancies and missed abortions was low. The forth was that Leptotrichia amnionii sp. nov. was the etiopathogenetic factor in missed abortion. 2. Transvaginal ultrasound assessment of irregular vaginal bleeding is effective in diagonosis of missed abortion. 3. There were medical therapy with misoprostol, mifepristone or anti progesterone for missed abortion. Misoprostol was administrated oral(sublingual) and vaginal.

• Journal of Biomedical Engineering Research
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• v.15 no.4
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• pp.395-400
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• 1994

High resolution spectral analysis is essential for ECG anaysis. The fast Fourier transform has been widely used for frequency analysis of ECG signals but this procedure provides poor resolution when the data record is short and shows Gibb's phenomena. The ARMA FTF (Fast Transversal Filter) algorithm is used for high resolution spectral analysis. The reason of unsalability of this algorithm is investigated and the method for improving the numerical stability is proposed. The proposed algorithm is applied to spectral analysis of the ECG. Since this result has less variations than the FFT based results, it can be used for the computerized diagonosis of the ECG.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.4
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• pp.256-268
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• 2006

Purpose : The purpose of this study was to investigate the clinical application of Traditional Korean Medicine(TKM) treatment to uterine myoma for TAH. Methods : Two patients were diagonosed as uterine myoma for TAH in other Obstetrics & Gynecology hospital. They were treated by herbal medicine with each diagonosis in our hospital, and the first case was also treated by acupuncture, moxibustion and herbal acupuncture. Results : After TKM, the uterine myoma size of the first case was reduced($12.2^{\ast}7.3cm{\to}9^{\ast}7cm$) significantly. And all the symptom of uterine myoma, Gonadotropin-releasing hormone(Gn-RH)'s side effects were improved. The metrorrhagia of the second case was stopped, and was not repeated during six month. The second symptoms of metrorrhagia were improved. So, the two cases don't need to have a TAH. Conclusion : The results indicate that TKM can be effective for the management of uterine myoma for TAH without operation. Further study will be investigated in TKM for healing uterine myoma for TAH completely.

• Proceedings of the KOSOMBE Conference
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• v.1994 no.12
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• pp.113-116
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• 1994

Estimation of the evoked potential using the iterated bispectrum and cross-correlation (IBC) has been tried for both simulation and real clinical data. Conventional time average (TA) method suffers from synchronization error when the latency time of the evoked potential is random, which results in poor SNR distortion in the estimation of EP waveform. Instead of EP signal average in time domain, bispectrum is used which is insensitive to time delay. The EP signal is recovered by the inverse transform of the Fourier amplitude and phase obtained from the bispectrum. The distribution of the latency time is calculated using cross-correlation between EP signal estimated by the bispectrum and the acquired signal. For the simulation. EEG noise was added to the known EP signal and the EP signal was estimated by both the conventional technique and bispectrum technique. The proposed bispectrum technique estimates EP signal more accurately than the conventional technique with respect to the maximum amplitude of a signal, full width at half maximum(FWHM). signal-to-noise-ratio, and the position of maximum peak. When applied to the real visual evoked potential(VEP) signal. bispectrum technique was able to estimate EP signal more distinctively. The distribution of the latency time may play an important role in medical diagonosis.

• Applied Chemistry for Engineering
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• v.24 no.1
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• pp.1-9
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• 2013

As the medical paradigm is changing from disease treatment to disease prevention and an early diagonosis, the demand to develop techniques for the detection of minute concentrations of biomolecules is increasing. Among the various techniques to sense the minute concentration of biomolecules, the biosensors utilizing the matured semiconductor techniques are presented here. To understand such biosensors, the structure and working principle of a MOSFET (Metal-oxide-semiconductor field-effect transistor) which is the basic semiconductor device is firstly introduced, and then the ISFET (Ion sensitive FET), BioFET (Biologically modified FET), Nanowire FET, and IFET (Ionic FET) are introduced, and their applications to biomedical fields are discussed.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.3
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• pp.1050-1060
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• 1996

Recently, attention has been paid to the flame diagnostic by noncontact methods which dose not deform the flame shape. One of them is a method which is using the radical luminous intensity. Generally, this diagnostic method using radical luminous has been investigated its reliability by applying to laminar flame. This study, however, investigated each radical luminous signals through stocastical analysis like auto-correlation, cross-correlation, phase and coherence which were acquired from measuring radical luminous intensity of OH, CH, $O_{2}$, radicals in turbulent diffusion flame. To compare radical luminous intensity in flame with temperature, ion current and concentration , radious distribution of each properties was investigated and considered. In radical luminous intensity, correlation in the reaction zone of flame was higher than in correlation in combusted gas zone. And radious distribution of radical luminous intensity was corresponded with radious distribution of temperature, ion current and concentration. The result of the study confirms that a radical luminous flame diagnosis is possible in the turbulent diffusion flame.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.22 no.3
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• pp.644-653
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• 1998

In resistance spot weld, the assurance of weld quality has been a long-standing problem. Since the weld nuggets if resustance spot welding form between the workpieces, visual detection of defects in usually impossible. Welding quality of resistance spot welding can be verified by non destructive and destructive inspections such as X-Ray inspection and testing of weld strength. But these tests, in addition to being time-consuming and costly, can entail risks due to sampling basis. The purpose of this study is the development of the monitoring system based on fuzzy inference, aimed at diagonosis of quality in resistance spot welding. The fuzzy inference system consists of fuzzy input variables, fuzzy membership functions and fuzzy rules. For inferring the welding quality(strength), the experimental data of the spot welding were acquired in various welding conditions with the monitoring system designed. Some fuzzy input variables-maximum, slop and difference values of electrode movement signals-were extracted from the experimental data. It was confirmed that the fuzzy inference values of strength have a .${\pm}$5% error in comparison with actual values for the selected welding conditions(9-10.5KA, 10-14 cycle, 250-300 $kg_f$). This monitoring system can be useful in improving the quality assurance and reliability of the resistance spot welding process.

• Research in Community and Public Health Nursing
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• v.4 no.1
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• pp.77-83
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• 1993

This study was carried out to idedtify Worker's general health diagnosis and specific health diagnosis state and provide the basic data about occupational health nursing services in Kyung Sang Nam Do. Data was obtained from 36 industry in Chang-won, Jin-joo, Geo-jeoi, Chung-moo area during Dec. 20. 1992-Feb. 18. 1993 through questionaire survey. Data was analyzed into frequency, percentage, average, standard deviation and score sum The main findings are as follows : 1) 83.3% of subject was manufactures. The factory which have over 1000 Worker's are 41.7% and 500-999 are 36.1%. 2) Health managers are composed of 5 man power. Doctors occupied in 44.4% of factories, average age of them are 43.9 years, average careers are 4.0 years. Nurses occupied in all factories and their average ages are 27.6, average careers are 3.0 years. Industrial hygienist occupied in 33.3% of factories, environmental hygienist occupied 69.4% of industries, and nurse aids occupied in 19.4%. 3) 99.9% of workers are received general health diagonosis. And 10.8% of workers are received elaborate health diagnosis. Among them 30.9% are C class and 23.4% are D class. Among D class, 50% of workers are treated as work time shortening, work replacement, being under treatment. Total specific health diagnosis' subject are 19.3% of workers but 79.9% of them are received specific health diagnosis. Among them 18.6% are needed follow up treatement. Only 44.9% of them are received follow up treatement. 4) 69.4% of industries have their referral hospital and 97.2% have their clinics. Among Occupational health services, health diagnosis are carried out first. of all and the next, environmental management, industrial diagnosis, health education are carried out.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.4 no.2
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• pp.199-206
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• 2001

Purpose: To review the clinical and laboratory features of patients with Wilson disease at diagnosis. Methods: In this retrospective study, records of all 20 patients, who were diagnosed as having Wilson disease at the Paik hospital in Busan from 1990 to 2000, were reviewed. Results: Out of 20 patients, 12 pateints (60%) have hepatic presentation alone, 2 patients (10%) have neurologic presentation, 4 patients (20%) have hepatic and neuropsychiatric presentation, and one patient (5%) has hematologic presentation at diagnosis. One patient (5%) has neither symptom nor laboratory finding of Wilson disease except very low serum ceruloplasmin level and positive family history. Family screening test revealed 3 cases of Wilson disease. 12 patients were revealed to be combined with liver cirrhosis at diagnosis. Conclusion: Early diagnosis and treatment is very important in patients with Wilson disease. Children or adolescents who manifest symptoms of hepatitis, who has prolonged elevation of liver enzymes, and has family history of hapatitis of unknown origin, with mild hematologic or urinary abnormalities must be suspected to have Wilson disease. Also, in adolescents with extrapyramidal symptoms or other neuropsychiatric symptoms, liver function test should be done.

• Applied Biological Chemistry
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• v.37 no.3
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• pp.182-188
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• 1994

Similar to the $^{42}K$ uptake, $^{86}Rb$ uptake by the roots of Hordeum distichum grown in the hydroponic culture was negatively correlated with the concentration of K supplied previously, showing that $^{86}Rb$ can be used for the K-bioassay. $^{86}Rb$ having longer half life (18.86 day) than $^{42}K$ (12.36 hr) allowed the use of larger number of root samples. $^{86}Rb$ uptake of 3 years old Citrus unshiu Marc. grown in water culture decreased drastically with the increase of K concentration of the culture solution, thus demonstrating that the nutrition status of K for citrus trees can be diagnosed by K-bioassay using $^{86}Rb$ tracer. $^{86}Rb$ uptake by the excised roots of Hordeum distichum grown in the pot with different K fertilizations was well correlated with the exchangeable K in soil. The amount of exchangeable K in soil for the optimal plant growth can be determined by its relationship. $^{42}K$ and $^{86}Rb-uptake$ by the Hordeum distichum roots were markedly inhibited by $5{\times}10^{-3}\; M$ KCN in the bioassay solution, indicating that uptake is energy-dependent. There was no significant relationship between K content in citrus leaves and K concentration in the water-culture medium. It is concluded that K-bioassay is a potentially useful tool for determining of K requirement in citrus trees.