• Title/Summary/Keyword: K$_{}$ op/

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The Effect of Cognitive Orientation to Daily Occupational Performance(CO-OP) on Upper Extremity Function and Occupational Performance in patients with Subacute Stroke (인지기반 작업수행 중재가 아급성기 뇌졸중 환자의 팔 기능 및 작업수행에 미치는 영향)

  • Sung-Jun, Moon;Hwan, Kim
    • Journal of the Korean Society of Physical Medicine
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    • v.17 no.4
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    • pp.123-132
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    • 2022
  • PURPOSE: The purpose of this study was to investigate the effects of cognitive orientation to daily occupational performance (CO-OP) interventions on the upper extremity function and occupational performance in subacute stroke patients. METHODS: A total of 30 eligible stroke patients were randomly distributed into the CO-OP experimental group (n = 15) and the traditional occupational therapy (OT) control group (n = 15). The CO-OP approach was applied for twelve 60-minute sessions. The Jebson Taylor Hand Function Test (JTHFT), the Korean version of the Modified Barthel Index (K-MBI), and the Performance Quality Rating Scale (PQRS) were used for outcome evaluations. RESULTS: There was a statistically significant difference in the paralytic upper extremity function before and after treatment (p < .01) between the group treated with the CO-OP approach and the group treated with traditional OT. The occupational performance of the CO-OP approach group showed a significant improvement (p < .01), and this group also showed a statistically significant improvement in quality of performance compared to the traditional OT group (p < .01). CONCLUSION: The CO-OP approach may be useful in clinical practice as a therapeutic intervention for improving the functional recovery and performance of subacute stroke patients. Future research should be carried out to investigate the persistence of this effect involving more participants and follow-up studies should also be undertaken.

Immuno-stimulating Effects of Oga-Power (OP) Containing Extract of Acanthopanax sessiliflorus on Immune Cells in Mice (오가피를 활용한 음료인 오가파워가 생쥐의 면역세포 활성화에 미치는 영향)

  • Kim, Hyung-Woo;Kim, Kyung-Yoon;Lee, Sang-Yeong;Kim, Gye-Yeop;Jeon, Byung-Gwan;Cho, Su-In;Jeong, Hyun-Woo
    • The Korea Journal of Herbology
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    • v.23 no.3
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    • pp.141-147
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    • 2008
  • Objectives : The cortex and root of Acanthopanax sessiliflorus (AR), a herbal medicine, have been used for several diseases including cancer in Oriental countries. Recently, we reported that AR has an immune-potentiating action. Oga-Power(OP) was made using extract from AR. For these reasons, we hypothesized that OP can potentiate the immune system in terms of accelerating proliferation rates of immune cells such as thymocytes and splenocytes. Methods : In this experiment, proliferation rates of thymocytes and splenocytes were measured using modified 3-[4,5-dimethy -lthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT). No production levels in macrophages isolated from normal mice were measured using Griess method. Results : In our results, treatment with OP accelerated proliferation rates of splenocytes, but did not affect those of thymocytes in vitro. On the other hand, proliferation rates of thymocytes was elevated in vivo. In addition, level of NO production from macrophage separated from abdominal cavity of normal mice was elevated by treatment with OP. Conclusions : In conclusion, OP has immune-potentiating action, by acceleration of splenocyte proliferation and elevation of NO production level from macrophages.

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Effects of Postnatal Exposure to Octylphenol on the Transcriptions of Steroidogenic Enzymes in Mouse Testis

  • Kim, Suel-Kee;Lee, Ho-Joon;An, Su-Yeon;Lee, Chang Joo;Yoon, Yong-Dal
    • Korean Journal of Environmental Biology
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    • v.22 no.4
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    • pp.550-558
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    • 2004
  • The effects of postnatal exposure to octylphenol(OP) on the expressions of the steroidogenic enzymes and testosterone production were evaluated. Postnatal male mice (15-day-old) were injected with 2 or 20mg $kg^{-l}$ body weight (BW) of OP for 5 days and sacrificed on postnatal day 21. Testosterone concentration was measured by radioimmunoassay and the expressions of the testicular genes were determined by RT-PCR analyses. Significant reductions in the mean body and testis weight were observed in the OP treated animals. No marked alteration in the histological structure of the testis were observed, however, slight reduction in the seminiferous tubule diameter and the number of Leydig cells and several pyknotic cells could be identified in the 20 mg $kg^{-l}$ BW of the OP treated animals. Serum testosterone concentration was dramatically reduced and the mRNA expressions of the steroidogenic acute regulatory protein (StAR), cholesterol side-chain cleavage enzyme (P450scc) and $17\beta$-hydroxylase/Cl7-20 lyase $(P450_{17\alpha})$ were decreased. No significant changes of the gene expressions of the steroidogenic factor-l (SF-I) and estrogen and androgen receptor after the OP treatment showed that the decreased expressions of the steroidogenic enzymes in the present study did not correlate with these genes. Altogether, the present study demonstrates that postnatal treatment of OP inhibits steroidogenesis by decreasing the transcriptional expressions of the StAR and steroidogenic enzymes. The alteration in steroidogenesis may adversely affect the normal development of the testis and sper- matogenesis.

A Case of Orthostatic Proteinuria Progressed to Persistent Proteinuria Associated with Renal Pathology

  • Kim, Yoo-Jin;Cho, Byoung-Soo;Ha, Tae Sun
    • Childhood Kidney Diseases
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    • v.21 no.2
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    • pp.152-155
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    • 2017
  • Orthostatic or postural proteinuria is the most common cause of asymptomatic proteinuria in children. As orthostatic proteinuria (OP) is a benign disease with relatively good prognosis, it has no specific management, and patients only need to be observed. However, if OP shows a persistently high level of proteinuria, in theory, glomerular changes can occur. An 11-year-old girl was referred to the hospital due to asymptomatic proteinuria and was diagnosed as having OP based on the results of clinical and laboratory examinations, urinalysis, and protein/creatinine (TP/Cr) ratio at both supine and erect positions. During follow-up observation, the 24-hour TP/Cr ratio was persistently higher than 1.5 mg/mg for 2 years. We performed renal biopsy, which showed mesangial proliferative glomerular lesions with focal effacement of the podocyte foot processes, but without immune depositions. OP can be accompanied by glomerular lesions if moderate to severe proteinuria persists.

Effects of Herba Cirsii Extracts on Glucose Uptake in OP9 Cells (OP9 세포에서 포도당 흡수능에 대한 대계 추출물의 효과)

  • Kim, Mi Seong;Song, Je Ho
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.2
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    • pp.195-199
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    • 2014
  • Although the Herba Cirsii is known to posses beneficial health effects, the anti-diabetic effects and the mechanism of action have not been elucidated. In the present study we have shown that Herba Cirsii Extract (HCE) can stimulate glucose uptake in OP9 adipocytes. Unlike insulin, HCE did not stimulate the Ser473 phosphorylation and activation of Akt. The increasing effects of HCE on glucose uptake were inhibited by PD680509 and compound C pretreatment, which means that the glucose uptake effects by HCE were carried out by extracelluar signal-regulated kinase1/2(ERK1/2) and AMP-activated protein kinase (AMPK) activation. Further studies revealed that HCE stimulated glucose transport occurs through a mechanism involving ERK1/2 activation and AMPK activation.

Throughput-Reliability Tradeoff in Decode-and-Forward Cooperative Relay Channels: A Network Information Theory Approach

  • Li, Jun;Chen, Wen
    • Journal of Communications and Networks
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    • v.11 no.5
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    • pp.445-454
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    • 2009
  • Cooperative transmission protocols are always designed to achieve the largest diversity gain and the network capacity simultaneously. The concept of diversity-multiplexing tradeoff (DMT) in multiple input multiple output (MIMO) systems has been extended to this field. However, DMT constrains a better understanding of the asymptotic interplay between transmission rate, outage probability (OP) and signal-to-noise ratio. Another formulation called the throughput-reliability tradeoff (TRT) was then proposed to avoid such a limitation. By this new rule, Azarian and Gamal well elucidated the asymptotic trends exhibited by the OP curves in block-fading MIMO channels. Meanwhile they doubted whether the new rule can be used in more general channels and protocols. In this paper, we will prove that it does hold true in decode-and-forward cooperative protocols. We deduce the theoretic OP curves predicted by TRT and demonstrate by simulations that the OP curves will asymptotically overlap with the theoretic curves predicted by TRT.

Influence of Thickness of Optical Panel on the Growth Rate of Chlorella vulgaris in Photobioreactor (광생물반응기에서 도광판의 두께가 Chlorella vulgaris 증식에 미치는 영향)

  • Choi, Hee-Jeong;Lee, Seung-Mok
    • Journal of Korean Society on Water Environment
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    • v.29 no.2
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    • pp.270-275
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    • 2013
  • The aim of this study was to investigate the efficiency of thickness of optical panel (OP) on the growth rate of Chlorella vulgaris. The size of Chlorella vulgaris (FC-16) was $3-8{\mu}m$, having round in shape. The cells of Chlorella vulgaris was cultured in the Jaworski's Medium with deionized water at $22^{\circ}C$ for 15 days. For this experiment, three OP samples were prepared to evaluate the efficiency of thickness of OP on the growth rate of Chlorella vulgaris; 4 mm OP with LED (Light Emitting Diode) (Run 1), 6 mm OP with LED (Run 2) and 8 mm with LED (Run 3). The diffuse rate was reached 86%, 91% and 92% for Run 1, Run 2 and Run 3, respectively. Average biomass of Run 2 and Run 3 were measured 11.18% higher than that of Run 1. However, the specific growth rate for all fractions were almost same. In addition, chlorophyll content per cell and cell volume were found to be slice difference between Run 2 and Run 3. Therefore, Run 2 has more effect on growth rate of biomass for Chlorella vulgaris than Run 1 and Run 3.

Effects of PCA (Patient Controlled Analgesics) Education Program including Practicum on Post-op Pain of Gynecologic Laparoscopic Surgery Patients (실물실습을 이용한 통증자가조절기 교육 프로그램이 부인과 복강경 수술환자의 수술 후 통증에 미치는 효과)

  • Hwang, Mi Sook;Kim, Joo Hyun
    • Journal of Korean Biological Nursing Science
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    • v.17 no.3
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    • pp.253-261
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    • 2015
  • Purpose: The purpose of this study was to identify the effects of the patient controlled analgesics (PCA) education program (including practicum) on post-op pain suffered by patients who have undergone gynecologic laparoscopic surgery. Methods: The research was designed for a nonequivalent control group before and after the test design. The subjects of this study were 54 in all and were divided into an experimental group and a control group. The program consisted of a brochure for PCA use and a practicum with an actual PCA instrument. Data were collected with questionnaires and observations and were analyzed on the basis of frequency, percentage, mean, standard deviation, ${\chi}^2$ and t-test. Results: Complaints regarding pain by the experimental group were significantly less than those of the control group in both post-op 24-hour and post-op 48-hour reporting. The experimental group pressed the PCA button much less frequently than the control group in post-op 24 hours. However, there were no significant differences in side effects between the two groups. Conclusion: Based on the results of this study, this PCA education program can be useful in the clinical nursing field and helpful for patients who use PCA.

Removal of Reactive Blue 19 dye from Aqueous Solution Using Natural and Modified Orange Peel

  • Sayed Ahmed, Sohair A.;Khalil, Laila B.;El-Nabarawy, Thoria
    • Carbon letters
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    • v.13 no.4
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    • pp.212-220
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    • 2012
  • Orange peel (OP) exhibits a sorption capacity towards anionic dyes such as reactive blue 19 (RB19). Cetyltrimethylammonium bromide (CTAB) as a cationic surfactant was used to modify the surface nature of OP to enhance its adsorption capacity for anionic dyes from an aqueous solution. Four adsorbents were investigated: the OP, sodium hydroxide-treated OP (SOP), CTAB-modified OP and CTAB-modified SOP. The physical and chemical properties of these sorbents were determined using nitrogen adsorption at 77 K and by scanning electron microscope and Fourier transform infrared spectroscopy techniques. The adsorption of the RB19 dye was assessed with these sorbents at different solution pH levels and temperatures. The effect of the contact time was considered to determine the order and rate constants of the adsorption process. The adsorption data were analyzed considering the Freundlich, Langmuir, Elovich and Tempkin models. The adsorption of RB19 by the assessed sorbents is of the chemisorption type following pseudo-first-order kinetics. CTAB modification brought about a significant increase in RB19 adsorption, which was ascribed to the grafting of the sorbent with a cationic surfactant.

Effect of modified-Okbyungpoongsan on mast cell-mediated allergic responses in RBL-2H3 mast cells (가미옥병풍산(加味玉屛風散)의 비만세포에서의 알레르기 반응에 대한 효과 연구)

  • Jung, Jin-Ki;Park, Yong-Ki
    • The Korea Journal of Herbology
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    • v.26 no.4
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    • pp.1-7
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    • 2011
  • Objectives : In this study, we investigated the effect of modified-Okbyungpoongsan (mOP) on mast cell-mediated allergic response in basophilic leukemia cell line, RBL-2H3 mast cells. Methods : Cells were stimulated with anti-DNP-IgE after the treatment of DNP-HSA (AI/D), and then incubated with different concentrations of mOP (0.1, 0.2, 0.5 and 1 mg/$m{\ell}$) in RBL-2H3 cells. Cell toxicity was determined by WST-1 assay. The degranulation of mast cells was observed by microscope with toluidine blue staining and also the levels of beta-hexosaminidase, histamine and TNF-alpha were measured in culture supernatants by enzyme-linked immunosorbant assay. Results : mOP inhibited anti-DNP-IgE-imduced degranulation of mast cells in RBL-2H3 cells. mOP also significantly decreased the levels of histamine and inflammatory cytokine, TNF-alpha in RBL-2H3 cells, but slightly decreased the level of beta-hexosaminidase. Conclusions : These results indicate that mOP, an oriental prescription could be inhibit the allergic response through suppressing the mast cell activation.