• 한국한의학연구원논문집
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• 제13권1호통권19호
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• pp.161-164
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• 2007

SsangHwaTang has been traditionally prescribed a medicine as a restorative. In this study, We investigated the acute toxicity about water-extracted SsangHwaTang. Twenty-five mice completed 14 days of oral SsangHwaTang at the respective doses of 0(control group), 2560, 3200, 4000 and 5000mg/kg. And then we observed survival rates, general toxicity, change of body weight, and autopsy. Compared with the control group, we could not find any toxic alteration in all treated groups (2560, 3200, 4000 and 5000mg/kg). In conclusion, LD50 of SsangHwaTang was over 5000mg/kg and it is very safe to ICR mice.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.93-99
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• 2008

Objectives: This study aims to find out the association between Sasang and Eight Constitution by analyzing Sasang and Eight Constitution Diagnosis results. Methods: We analyzed Sasang and Eight Constitution Diagnosis results according to confidence, by reviewing medical records of 247 patients retrospectively whose Sasang and Eight constitutions were diagnosed by two independent specialists. We used chi-square test and Cramer Statistic to know association of two diagnosis results. Results and Conclusions: Taeumin was 49.8% in Jupita, Soeumin 65.2% in Mercuria, Soyangin 90.9% in Saturna, Taeumin was 54.2% in Jupita, Soeumin 83.4% in Mercuria, Soyangin 100% in Saturna in condition that Sasang and Eight Constitution diagnosis confidence is over Band 50 score. The higher diagnosis confidence is, also the higher association between Sasang and Eight Constitution is up to 0.414(Cramer Statistic). There is association between Sasang and Eight Constitution.

• 동의생리병리학회지
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• 제26권3호
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• pp.392-398
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• 2012

This research aims to analyze the ethical requirements and to find the problems for the publication guidelines of oriental medicine journals. A total of 13 domestic journals, related to oriental medicine and registered in 'National Research Foundation of Korea' list, were selected for the analysis of ethical requirements. We inquired the revised year of the publication guideline and the status of ethics committee of selected journals. The ethical requirements of publication guidelines were evaluated by categorizing them into Institutional Review Board(IRB), Helsinki Declaration, Informed Consent, confidentiality and anonymity of subjects, and conflict of interest. In the case of revised year of the publication guidelines, the year of the most recently revised journal was 2011. However, the revised year of publication guidelines were not announced for three journals and a few journals haven't revised the publication guidelines since 2002. In the case of ethics committee status, four journals out of 13 journals maintained the ethics committee. In the result of ethical requirement analysis, nine journals included the information for confidentiality and anonymity of subjects, and four journals included the information for Helsinki Declaration and Informed Consent. However, only one journal included the information for IRB and conflict of interest. Recently, the importance of clinical researches has been increased to prove the effect of oriental medicine scientifically and objectively. The clinical researches should be considered in scientific side and ethical side as well, because they have potential risks to human subjects. In this sense, announcing the ethical requirements in the publication guidelines can be one way to secure the morality of researches. Thus, it is required to prepare correct publication guidelines and ethical requirements in oriental medicine journals.

• 동의생리병리학회지
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• 제21권5호
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• pp.1337-1340
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• 2007

Pulse diagnosis is one of the typical examination methods in traditional oriental medicine. However, it is necessary to obtain the objectivity for the standardization of this diagnosis. For this purpose, the pulse analyzer has been devised and studied, and the tonometric pulse analyzer displaying the pulse wave and its variables was developed recently. In this study, we investigated the effect of the sexuality of the individuals on the differences of the pulse wave as well as the correlation between the weight and the pulse wave to interrogate whether the pulse difference is not caused by the difference of sex but the size of individual.

• 한국한의학연구원논문집
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• 제14권3호
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• pp.65-71
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• 2008

Objectives : We intended to know the association between Psychosocial Well-being Index(PWI) and health behaviors and also know the useful health guide according to Sasang Constitution Methods : We recruited the 137 subjects from oriental medical clinics around the country and the expert diagnosed Sasang constitution with drug response guide. We used the PWI-SF paper to estimate psychosocial well-being. We used excel program and analyzed with SPSS 14.0K Results : 1. PWI were associated with no passive smoking, everyday regular exercise, eating anything, much eating vegetable and sea-food, no eating snacks. 2. PWI were associated with no passive smoking, 4-5 times regular exercise a week, unconcern in sanitary thought, less or normal amount of meals in Soeumin, no smoking in Taeeumin, and there were not particularly associated ones in Soyangin Conclusions : Health behaviors for PWI are a little different according to Sasang Constitution.

• 한국한의학연구원논문집
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• 제13권2호통권20호
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• pp.121-125
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• 2007

Background and Purpose : The purpose of this study was done to investigate what kinds of statistical techniques have been used to analyze data from oriental medicine research Methods : 135 original articles which used statistical techniques in their data analysis were selected from the articles published in The Journal of Korea Institute of Oriental Medicine(JKIOM) between 1995 to 2007. Results : Among 135 articles, 59 articles used descriptive statistics while 76 articles used inferential statistics for data analysis. For that 76 articles, two-sample t-test(33 articles), analysis of variance(29 articles), regression(9 articles), chi-square test(5 articles), nonparametic test(4 articles), Fisher's exact test(3 articles), and other test(9 articles) were chosen to analyze the data. SAS and SPSS statistical softwares(82.50%) were mostly used to analyze the data. Nonparametic tests were used to 4 articles(6.97%) of 67 articles and parametic tests were used to 63 articles(93.03%) of 67 articles. Among 29 articles used analysis of variance, duncan(8 articles), dunnet(4 articles), bonferroni(4 articles), turkey(3 articles), scheff(1 article) were used to do multiple comparison. 9 articles did not carry out the multiple comparison. Conclusions : It was found that the frequencies of statistical package used and statistical analysis used were not much by now. High level statistical analyses were not used most for oriental medicine research.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.1-10
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• 2008

Noh Jungrye(盧重禮) can be cited as an representative royal doctor of early Chosun dynasty. He collaborated in the development of korean medicine out of the influence of chinese medicine. He made an systematical approach on supply and propagation of The Native Herb Medicine(鄕藥) which promoted the independence of Korean medicine. The edition of "HyangYakJibSungBang(鄕藥集成方)"(Compendium of Prescriptions from the Countryside) was the result of this effort establishing the originality of Korean medicine. He also strengthened in the medical support new born child editing "TaeSanYoRok(胎産要錄)" as their mortal rate was high in that time. In social-political aspect, being appointed in Dangsanggwan(堂上官) as a doctor, was controversial as even after his death this discussion kept on. On the other hand this designation prompt other doctors to devote in Korean medicine.

• 한국한의학연구원논문집
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• 제10권2호
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• pp.51-62
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• 2004

Through the survey of related studies for last ten years, it was known that accurate sample data of sasang constitution are the most important condition in sceintific research of sasang constitutional medicine. So we can propose three step for scientific sasang constitution medicine: firstly, the construction of SCIM(Sasang Constitutional Information Bank); secondly, the development of instruments for constitution diagnosis; thirdly, the new diagnosis methods based on the organic definition of sasang constitution.

• 동의생리병리학회지
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• 제25권4호
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• pp.755-758
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• 2011

Sasang Constitutional Medicine (SCM) suggests the concept of health condition which is owned of different properties by each Sasang Constitution. But SCM theory has concentrate to explaining different symptoms that distinguish health condition, not much concerned with practical methods like face features, pulse diagnosis, skin surface properties and voice features. Physical properties of practical diagnosis methods from literature finding have been researched. As a result, complexion and face moisture were described to be physical properties related to health State. In scope of pulse diagnosis, depth, rate, contour, width and pressure are related. Skin surfaces' elasticity, moisture, fraction properties were also suggested as factors of health State of Sasang Constitution. We assume that this study would contribute further studies for objectifying and quantifying diagnosis methods to evaluate health state grades of Sasang Constitution.

• 대한한의학회지
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• 제32권6호
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• pp.85-94
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• 2011

Objectives: This pilot study was carried out with the purpose of suggesting a methodology on mapping and registering Korean medicinal material concepts at 2011AB of the UMLS. Methods: 411 medicinal material concepts were mapped to biomedical terminology within the metathesaurus of the UMLS. Based on the forms of listing on the UMLS and thesauri information, the medicinal material concepts were classified into three groups and mapped. Results: 76 concepts in Group 1 which English CUIs have Chinese AUIs were mapped considering scientific names and Chinese strings. 259 concepts in Group 2 that have CUIs in the form of 'botanical name/Chinese pinyin' were mapped with the information of Korean and Chinese Pharmacopoeias. Groups 3, 76 concepts of English names in the Korean Pharmacopoeia are matched considering their botanic names and used parts. Conclusion: This study suggested a methodology to map Korean medicinal material concepts to international standard terminology, which will help ensure interoperability and compatibility between traditional medicine terminology and the UMLS.