• 대한한방소아과학회지
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• 제16권2호
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• pp.171-185
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• 2002

Objectives : The purpose of this study was to investigate the spine distortion and self-conscious pain in high school students. Method : Using the phase-shifting moire developed by KAIST(Korea Advanced Institute of Science and Technology) we measured the back surface distortion, and using questionnaire investigation, we investigated the self-conscious pain in 30 high school students(17 boy students and 13 girl students). Results : This study show that low back pain was most cases, and next headache, upper back pain, abdominal pain, neck pain, shoulder pain, leg pain, chest pain and gluteal pain. The ratio of each self-conscious pain was 90.0%, 86.7%, 83.3%, 83.3%, 80.0%, 76.7%, 66.7%, 33.3%, 33.3%, 30.0%. In remainder value of left and right shoulder, above of 3.0 were three students., above 2.0 to bellow 3.0 were 10 students, bellow 2.0 were 17 students. In remainder value of left and right gluteal, above of 2.0 was one students, above 1.0 to bellow 2.0 were 18 students, bellow 1.0 were 10 students. In remainder value of cervical vertical line to left and right axillae, above 4.0 was 1 student, above 3.0 to bellow 2.0 were 2 students, above 2.0 to bellow 3.0 were 3 students, above 1.0 to bellow 2.0 were 16 students, bellow 1.0 were 7 students. In remainder value of gluteal vertical line to left and right axillae, above 6.0 was 1 student, above 5.0 to bellow 6.0 were 7 students, above 4.0 to bellow 5.0 were 3 students, above 3.0 to bellow 4.0 were 2 students, above 2.0 to bellow 3.0 were 5 students, above 1.0 to bellow 2.0 were 7 students, bellow 1.0 were 5 students. In remainder value of cervical vertical line to gluteal vertical line, above 40 was 1 student, above 3.0 to bellow 4.0 were 4 students, above 3.0 to bellow 3.0 were 6 students, above 1.0 to bellow 2.0 were 8 students, bellow 1.0 were 11 students. Conclusion : It is suggested that the significant correlation exist between the spinal distortion and self-conscious pain. And we can find many cases as spinal distortion in high school students also. We have to study further more about juvenile postural distortion and it's prevention.

• 한국응용과학기술학회지
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• 제39권3호
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• pp.442-453
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• 2022

다양한 동물 모델이 인간 질병, 의약품의 효능 및 작용 메커니즘을 연구하는 데 사용되고 있다. Zebrafish(Danio rerio)는 여러 가지 장점이 있어 인간 질병에 대한 중개 연구의 모델로 점점 더 폭넓게 활용되고 있다. 본 논문은 Pubmed, Google Scholar, Scopus에서 2020년 12월까지 최근 10년간 zebrafish 모델, 천연물(한약), in vivo 스크리닝의 키워드를 사용하여 저널에 게재된 논문을 검토하여 필요한 정보를 얻었다. 이 리뷰에서 우리는 천연물(한약) 연구에 대한 다양한 제브라피쉬 질병 모델의 최근 경향에 대해 논의하였다. 특히, 암, 안질환, 혈관 질환, 당뇨병 및 합병증, 피부질환에 중점을 두었고, zebrafish 배아를 사용하여 이들 질병에 대한 의약품의 분자 작용 메커니즘에 관해 언급하였다. Zebrafish는 실험실에서 임상 연구까지의 격차를 줄이는 데 중추적 역할을 할 수 있는 중요한 동물 모델이다. Zebrafish는 의약품이나 화장품 개발, 질병의 병인론을 이해하기 위해 사용되고, 이로 인해 생의학 연구에서 설치류의 사용을 줄이는 데 크게 기여하고 있다.

• 동의신경정신과학회지
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• 제21권1호
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• pp.59-69
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• 2010

Objectives: The study aims to look into how the application of EA(Electro-acupuncture) in the initial step of ischemic brain injury affects the changes in Bax and Caspase-3 expression among forebrain apoptosis. Methods: It caused GI by using common carotid artery occlusion and conducted the test by dividing into the no applied EA group after 6 hours and 12 hours, the LI 4 EA group that applied EA to LI4, and GV 20 EA group that was applied to GV 20. After that, the following results were obtained by comparing Bax and Caspase-3 expression, which were apoptosis-related factors, with its application time through immunohistochemical staining after extracting brain of each group. Results: According to each group's Bax expression by the application time, the order of expression increase after 6 hours is shown to be the no applied EA group, LI 4 group, and GV 20 group. The stimulation after 12 hours was most lowly expressed in the GV 20 group, and the no applied EA group and LI 4 group showed similar level. Conclusions: EA stimulation in the initial step after ischemia seems to affect positively Bax and Caspase-3 expression that are index of forebrain apoptosis.

• 한국의사학회지
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• 제22권2호
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• pp.99-109
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• 2009

Jejung Sinpyeon (New Edition of Medical Prescriptions) is a medical book that was compiled in order to overcome the shortcomings of Donguibogam (Exemplar of Korean Medicine), to improve and offer prescriptions suitable for new diseases according to the changing times, and simply to publish new medical books. As a result of an analysis of Yakseongga of Jejung Sinpyeon (a book of medicine written by Kang Myeong-gil in 1799, the 23rd year of the reign of King Jeongjo of the Joseon Dynasty), it was found that a total of 303 lines had been quoted from Wan-bing-hui-chun of the Ming Dynasty of China] and Dongeui Susebowon and that 83 lines had been newly inserted by the author. Of the 303 lines, 296 were quoted from Dongeui Susebowon, and only seven from Wan-bing-hui-chun. This means that the author of Jejung Sinpyeon chiefly used Dongeui Susebowon as the source of Yakseongga quoted therein. 275 lines, or 76%, of a total of 386 lines of Yakseongga of Jejung Sinpyeon, have their Korean names marked. Medicinal herbs marked as Chinese herbs number 83 out of 386. Among the 83 herbs named, one belongs to the part newly inserted by the author, while the remaining 82 are quoted from Yakseongga. The foregoing suggests that the author expected that the knowledge could be used by people easily based on an effort to make it localized knowledge, although Yakseongga was compiled based on quotations from Chinese literature. Yakseongga of Jejung Sinpyeon has significant value as the country's first State-compiled book of medicine to contain Yakseongga.

• 대한한방부인과학회지
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• 제34권4호
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• pp.1-11
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• 2021

Objectives: Nephrotic syndrome is a kidney disorder, which is characterized by proteinuria, edema (swelling), and hyperlipidemia. Maydis Stigma (Corn silk) has been widely used in Asia as a traditional medicine and is known to have a diuretic effect and is used for the treatment of edema and indigestion. Methods: The aim of this study is to investigate the improvement effect of Maydis Stigma in treating nephrotic syndrome induced by puromycin aminonucleoside. Sprague-Dawley rats were intravenously injected with 75 mg/kg/day puromycin aminonucleoside, then treated with either Losartan or 200 mg/kg/day Maydis Stigma for seven days. Results: Maydis Stigma significantly decreased ascites and proteinuria level. Plasma levels of blood urea nitrogen (BUN) and plasma creatinine reduced significantly by Maydis Stigma. In addition, treatment with Maydis Stigma attenuated histological damage. Treatment with Maydis Stigma also restored podocin expression and reduced inflammation markers such as intracellular adhesion molecules (ICAM-1), monocyte chemotactic protein-1 (MCP-1), tumor necrosis factor alpha (TNF-α) and high-mobility group box-1 (HMGB1). Conclusions: Maydis Stigma ameliorates kidney injury in nephrotic syndrome rat models. Maydis Stigma exerts a renoprotective effect owing to its anti-inflammatory effects and reductions of ascites and proteinuria. Thus, these results indicate that Maydis Stigma is likely to be a promising agent in the treatment of nephrotic syndrome.

• 한국식생활문화학회지
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• 제31권6호
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• pp.541-553
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• 2016

Medicinal porridge (藥粥) is made by putting rice or grains into a pot and boiling with water until a semi-liquid texture is obtained. Porridge is digested fast and absorbed by the body. Children or elderly people with weak digestive ability can eat it without difficulty. The authors of this literature focused on utilization of mung bean porridge (Nokdu-juk) based on SeungjeongwonIlgi (承政院日記), which is the daily record of the Royal Secretariat of the Joseon Dynasty from 1623 to 1910. Four cases were found. The first case used mungbean for treating fever diseases (熱症), the second as a meal alternative, the third for wound recovery, and the last case described the culture of the joseon dynasty. According to the actual cases in SeungjeongwonIlgi (承政院日記), mung bean porridge (Nokdu-juk) was actively used to lower fever and strengthen the spleen and stomach. When suffering from the after effects of a malignant tumor or serious liver disease (肝病), an infectious disease, or a serious physical wound, people ate mung bean porridge (Nokdu-juk). It is suggested that mung bean porridge (Nokdu-juk) can be used as an alternative food treatment for the current medical field due to the prevalence of pain-killers and psychotropic drug abuse.

• 대한본초학회지
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• 제26권1호
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• pp.7-12
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• 2011

Objectives : The purpose of this study is to evaluate the quality of four different kinds of agarwood and analysis chemical constituents by GC-MS. Methods : Four source plants were two of Vietnamese agarwood, Indonesian agarwood and Myanmar agarwood. These plant materials were named sample No. 1-4. The chemical constituents of each agarwood were analysed by GC-MS. Results : GC-MS analysis showed that ${\beta}$-selinene was found in all the samples. The Vietnamese agarwood, Sample 1, and 4 has contained 6.861% and 7.497% of ${\beta}$-selinene and reached the highest level at the retention times 46.245 and 46.274 (min). Sample 2, the Myanmar agarwood has contained 1.608%, the lowest level of ${\beta}$-selinene, and it also has contained about 20% of ${\alpha}-,{\beta}-,{\gamma}$-eudesmol and 4.076% of valerianol. Sample 3, the Indonesian agarwood has contained 9.59% of ${\beta}$-selinene, 9.493% of ${\beta}$-selinene and shown its highest level (more than 19%) at the retention time 43.998 (min). Conclusion : It suggested that ${\beta}$-selinene could be a standard marker to evaluate agarwood by GC-MS analysis.

• 정보관리연구
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• 제40권4호
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• pp.93-108
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• 2009

중국정부는 중의약의 발전을 도모하고자, 1988년에 중국중의약관리국을 개설하여 매년마다 전국중의약통계적편(全國中醫葯統計摘編)을 대내외에 공개하고 있다. 이것은 중국의 중의약 인프라에 대한 체계적인 관리를 통해 중의약을 향후 세계시장에서 선점하고자 하는 의도로 판단된다. 전국중의약통계적편(全國中醫葯統計摘編)의 통계는 초기에는 구성도 체계화되지 못하였으나, 해를 거듭할수록 통계의 구성 내용이 다양화되었으며, 체계화 및 표준화되고 있음을 알 수 있다. 뿐만 아니라, 중의자원, 중의 의료기구 운영 및 서비스, 중의교육, 중의약과학연구 및 사업비에 대한 투자를 증가시켜 동양의약의 주도권을 잡기 위한 노력을 엿볼 수 있다. 이에 본 논문에서는 중국중의약관리국에서 매년 발표하는 전국중의약통계적편(全國中醫葯統計摘編)에 대한 구성 체계, 구축현황, 통계작성 제도에 대한 구성분석과 연도별 중의자원, 중의의료기구 운영 및 서비스, 중의교육, 중의약과학연구 및 사업비에 대한 변동 추이에 대한 내용분석으로 나누어 중국의 중의약 발전을 위해 어떤 노력을 하고 있는지 알아보고자 하였다.

• 대한본초학회지
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• 제23권2호
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• pp.1-8
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• 2008

Objectives : The purpose of this study was to evaluate on the antimicrobial effect on the periodontal pathogens and anti-inflammatory effect of Artemisiae Iwayomogii Herba. Artemisiae Iwayomogii Herba has been used for treating as Artemisiae Capilaris Herba in Korea. Methods : Artemisiae Iwayomogii Herba was prepared by extracting medicinal herb with water. We investigated antimicrobial activity by the minimun inhibitory concentration (MIC) test. We also investigated inhibition of IL-$1{\beta}$-induced collagenase-l(MMP-l), stromelysin-1(MMP-3), interleukin-6 gene expression in human gingival fibroblasts. Results : The antimicrobial effect of Artemisiae Iwayomogii Herba was evaluated with MIC against periodontopathogens; Porphyromonas gingivalis 2561, W50, A7A1-28, 9-14K-1, Prevotella intermedia28, and Actinobacillus actinomycetemcomitans Y4, MICs of Artemisiae Iwayomogii Herba were 0.156 mg/ml, 0.625 mg/ml, 0.313 mg/ml, 1.25 mg/ml, 10 mg/ml and 10 mg/ml. The anti-inflammatory effect of Artemisiae Iwayomogii Herba was evaluated with Influence of herbs on the IL-$1{\beta}$-induced expression of MMP-1, MMP-3, interleukin-6, IL-$1{\beta}$ increased MMP-1, MMP-3, interleukin-6 mRNA levels. Artemisiae Iwayomogii Herba significantly inhibited IL-$1{\beta}$-induced MMP-1, MMP-3, interleukin-6 gene expressions in a dose-dependent manner. Conclusions : These results suggested that Artemisiae Iwayomogii Herba might reduce the excessive proteolytic capacity of the gingival fibroblast during inflammation and could be developed a new drug in periodontitis.

• 한국의사학회지
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• 제28권2호
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• pp.97-103
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• 2015

The medical information of Lee-Kyukyeong has been considered as one of the cases delivering western medical knowledge, attracting public attention. The medical theories delivered from western countries were very unfamiliar and unique however he knew that e dissection information of East Asia was more detailed compared to the dissection theories of East Asia left in East Asia. And, he made a valuation of the East Asian traditional medical information related to human body in the book. However, the information that he left was mixed with medical books, many written statements and encyclopedias in fashion etc. and many information written by him delivers very unique legends with the confirmation of the information about the human body. Therefore, there are many cases that these information are hard to be discussed at the same level and there are wrong information in therms of 'Fact' and introductions in terms of opposite contetns in the same article. This is originated from the advantages and limits that "OhjuYeonmunJangjeonSango" has, whose author tried to collect the knowledge as much as possible in the same frame under the identical topic. This is the example that shows the climate of the some intellectuals who made an example by accepting all kinds of information and making information of their own. This intelligent climate clearly shows the discordance between medical information suggested by Ohju and the medical reality that Ohju faced. In other words, there were latest information in "Ohju-Yeonmun-Jangjeon-Sango", but had to be sensitive in supply of medicines for Ohju who used to live in the backwoods. Therefore, the medical benefits that he could choose were single - medicine prescription that is closer to conventional medicine and experiential prescription and Yangsaengsoo which medical costs do not occur. These facts imply that the stories about the latest opinion that was in fashion to look at the medical reality in late Chosun Dynasty and detailed research on the daily life that one person faced should be accompanied.