• The Korean Journal of Physiology and Pharmacology
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• v.12 no.2
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• pp.83-87
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• 2008

The fyn-related kinase (FRK) belongs to the tyrosine kinase family of protein kinases. Recent studies have shown that Frk affects pancreatic beta cell number during embryogenesis and promotes beta cell cytotoxic signals in response to streptozotocin. To investigate the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density lipoprotein) of blood sample from each subject were also measured. One hundred fifty five healthy control and 204 overweight/obesity subjects were recruited. Genotype frequencies of six SNPs [rs6568920 (+8391G>A), rs3756772 (+56780A>G), rs3798234 (+75687C>T), rs9384970 (+68506G>A), rs1933739 (+72978G>A), and rs9400883 (+75809A>G)] in the FRK gene were determined by Affymetrix Targeted Genotyping Chip data. According to the classification of Korean Society for the Study of Obesity, control (BMI 18 to < 23) and overweight/obesity (BMI$\geq$23) subjects were recruited. For the analysis of genetic data, EM algorithm, SNPStats, Haploview, HapAnalyzer, SNPAnalyzer, and Helixtree programs were used. Multiple logistic regression analysis (codominant, dominant, and recessive models) was performed. Age and gender as covariates were adjusted. For biochemical data, Student's t test was used. The mean value of BMI in the control and overweigh/obesity groups was 21.1${\pm}$1.2 (mean${\pm}$SD) and 25.6${\pm}$2.0, respectively. All biochemical data of the overweight/obesity group were statistically significance, compared with the control group. Among six SNPs, two linkage disequilibrium (LD) blocks were discovered. One block consisted of rs1933739 and rs9400883, and the other comprised rs3756772 and rs3798234. One SNP (rs9384970, +68506G>A) showed an association with overweight/obesity in the codominant model (p=0.03). Interestingly, the AA genotype distribution in the overweight/obesity group (n=7, 3.5%) was higher than those in the control group (n=1, 0.6%), which is not found in either Japanese or Chinese subjects. Therefore, the AA genotype of rs9384970 may be a risk factor for development of obesity in Korean population. The results suggest that FRK may be associated with overweight/obesity in Korean population.

• Journal of the Korean Geographical Society
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• v.47 no.2
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• pp.159-178
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• 2012

Since the suggestions on the paleo-glacial landforms in and around the northern high mountains of Korean Peninsula by some western and Japanese scientists in the early 1900s, the likelihood of the glacier existence in the Baekdusan over the Quaternary glacial period has been had in common among most of the Korean geomorphologists. In the other meaning, some have cast doubt on the likelihood the paleo-glacier in the Baekdusan because there has been no unequivocal evidences for the glacier such as striation, moraines, except morphologic characteristic landforms possibly related to glacier. Here we show some evidences for the existence of the glacier in the Baekdusan and their cosmogenic $^{36}Cl$ exposure ages over the late Quaternary and would put forward a model on the Quaternary landscape evolution of the Baekdusan, with a focus on the relationship of 1000 AD explosive eruption and the glacial landforms. The exposure ages constrained by cosmogenic $^{36}Cl$ abundances of the col surface of the western slope located below the glacier yield 46~26 ka, which is inphase with the last glacial period. Given all the evidences above, we can draw a conclusion that the glacier existed on the Baekdusan over the late Quaternary and the style of glaciation changed from extensive ice cap through valley glacier to restricted cirque.

• Economic and Environmental Geology
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• v.47 no.2
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• pp.133-146
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• 2014

There are many studies for the economic impact assessment of natural disasters, but there are few for volcanic disasters. Domestic academic research is not under active discussion because of the lack of national and social interest for volcanic eruption. This study investigated the research methodology for the economic impact assessment of natural disasters and discussed whether these can be applied to the economic impact analysis for the Baekdu Mountain volcanic disaster. The main findings are as follows: Firstly, Asia-Pacific region is the most affected by natural disasters and has the largest scale of damage. Asian and American Continent have the most economic damage. Secondly, Considering the types of damage caused by natural disasters and its complex structure, several methodologies that could be possible to estimate economic consequential damages have been compared. When applying each methodology to the Baekdu Mountain volcanic disaster, the scale of damage is likely to be over-estimated or under-estimated because of model-specific features. Thus, estimated values should be compared to each other after calculating the damage results. Thirdly, Japanese academic research on the volcanic disaster will be used as the starting point of the economic impact assessment studies for Baekdu Mountain. Using computer SW such as Hazus which is used in United States and RiskScape from New Zealand is also a good method to predict economic impact of the Baekdu Mountain volcanic disaster.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1998.11a
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• pp.25-29
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• 1998

본 논문은 얼굴 인식 또는 표정 인식 분야에 있어서 중요한 특징을 나타내는 얼굴과 얼굴의 주요소인 눈과 입, 눈썹의 영역 추출 및 그의 윤곽선·추출에 관한 방법을 제시한다. 얼굴요소의 영역 추출은 엣지 정보와 이진화 영상을 병합하여 이용한 프로젝션 분석을 통하여 얼굴 및 각 얼굴요소를 포함하는 최소포함사각형(MER: Minimum Enclosing Rectangle)을 추출하였다. 얼굴 영상에 관련된 윤곽선 연구에는 가변 템플릿(Deformable Template), 스네이크(Snakes: Active Contour Model)를 이용하는 연구들이 이루어지고 있는데 가변 템플릿 방법은 수행시간이 느리고 추출된 윤곽선의 모양이 획일 된 모양을 갖는 특성이 있다. 본 논문에서는 사람마다 얼굴요소의 모양의 개인차가 반영되고 빠른 수렴을 할 수 있는 스네이크 모델을 정의하여 눈, 입, 눈썹, 얼굴의 윤곽선 추출 실험을 하였다. 또한 스네이크는 초기 윤곽선의 설정이 윤곽선의 추출 곁과에 큰 영향을 미치므로, 초기 윤곽선의 설정 과정이 매우 중요하다. 본 논문에서는 얼굴 및 각 얼굴요소를 포함하는 각각의 최소 포함 사각형(MER)을 추출하고, 이 추출된 MER 내에서 얼굴 및 각 얼굴요소의 일반적인 모양을 초기 윤곽선으로 설정하는 방법을 사용하였다. 실험결과 눈, 입, 얼굴의 MER의 추출은 모두 성공하였고, 눈썹이 흐린 사람들의 경우에만 눈썹의 MER추출이 졸지 않았다. 추출된 MER을 기반으로 하여 스네이크 모델을 적용한 결과, 눈, 입, 눈썹, 얼굴의 다양한 모양을 반영한 윤곽선 추출 결과를 보였다. 특히 눈의 경우는 1차 유도 엣지 연산자에 의한 엣지 와 2차 유도 연산자를 이용한 영점 교차점(Zero Crossing)과 병합한 에너지 함수를 설정하여 보다 더 나은 윤곽선 추출 결과를 보였다. 얼굴의 윤곽선의 경우도 엣지 값과 명도 값을 병합한 에너지 함수에 의해 비교적 정확한 결과를 얻을 수 있었다.잘 동작하였다.되는 데이타를 입력한후 마우스로 원하는 작업의 메뉴를 선택하면 된다. 방법을 타액과 혈청내 testosterone 농도 측정에 응용하여 RIA의 결과와 비교하여 본 바 상관관계가 타액에서 r=0.969, 혈청에서 r=0.990으로 두 결과가 잘 일치하였다. 본 실험에서 측정된 한국인 여성의 타액내 testosterone농도는 107.7$\pm$12.0 pmol／l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol／l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Letter Jobcheso." Therefore, the purpose of this study is to look into the origin of the letter designs in the Chinese character culture

• Journal of Korean Society of Rural Planning
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• v.6 no.1 s.11
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• pp.19-28
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• 2000

Now in order to overcome the weakest points of the rural areas of the city of Kimje and, transform them into rural cultural villages which have local governing systems suitable to new localization age and activate this plan, we selected Daesan Village as a model village which had shown a lot of potentials in the basic research and studied it dividing it into the former part and the latter part. We studied Daesan village in the former part focusing on state analysis and basic ideas and in the latter part focusing on master plan and detail planning. We can summarize the conclusion like the followings. 1. Daesan Village located 8 kilometer away from the downtown Kimje and the city of Iksan respectably has comparatively good environment of good sunny place as an open field whose surrounding configuration of the ground consists of farming lands and low hills in front and rear. It has 38 farming households in all. 2. Human environment(인문환경); the village road whose width is about 4 meters is forming a flow system forking off into three. There is a route bus which operates three times a day even into the inside of the village. The main sources of revenue are vegetables in facilities, fruits and floriculture. Their average revenue is about 10.5 million won. 3. Here in DaeSan Village a legend dealing with Teasan literally meaning a big mountain consist of th village's tradition and you can see the tombs of a very faithful son and Anwi an army general in the age of the Japanese Invasion of Korea of 1592 to 1598 inside the village. 4. 85 out of the eitire population 141 whose age are over 20 showed very positive attitudes in a questionnaire about, making the village a cultural one and its development. 5. The basic of planned ideas is to increase the revenue of the farming household by making the village a professional farming one which has a state-of the-art production facility and agricultural technique. It is to make the village the one where people can enjoy the sense of the rural life and the farmer can enjoy their lives through consumptive and consistant leisure and resting activities. 6. We are planning to make entrance space, life space, rest and sport space, and cultural space considering the characteristics of the village and the demand of the resident. We are also planning to make tile entire city of Kimje an information transmitting base in short and long term perspectives. 7. DaeSan Village was planned as a place where tradition and the future exist together. On the basis of this concept we planned future programs for Daesan Village and in the latter part of the study master plans and detail plans will be continued.the regional agricultural condition. The development permissions were only during the period of restricted to use ($1979.12{\sim}1993.11$). We propose that the authority of development permission should be given to the local autonomy government, because the local government has the knowledge of its individual agricultural conditions.

• The Journal of Korean Medical History
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• v.17 no.1
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• pp.31-55
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• 2004

For the sake of the Restoration(to the original state) of "Sanbeon-bang(刪繁方)", in this study observed carefully the bibliographical results of "Oedaebiyo-bang", "Cheongeumyo-bang", "Cheongeumik-bang" and "Uisim-bang", which directly quoted "Sanbeon-bang". "Sanbeon-bang" is mostly remained in "Oedaebiyo-bang", and the other provisions of "Sanbeon-bang" mostly lie scattered in "Cheongeumyo-bang" and "Cheongeumik-bang", established 100years before "Oedaebiyo-bang" and "Uisim-bang", established 200years after "Oedaebiyo-bang". And there are few other documents which quoted the "Sanbeon-bang". "Cheongeumyo-bang", a synthetic medical work was compiled in 652, and which refered large quantity of medical documents before Dang-dynasty(唐代) by Son Sa-mak(孫思邈). And he linked the technical opinion of himself. The comments of medicine, as well as the prescriptions are refleting the outcome before Dang-dynasty systematically. For the most part of the medical arguments in "Sanbeon-bang" lie scattered in "Cheongeumyo-bang". "Cheongeumik-bang", also a synthetic medical work which is for the sake of supplement of "Cheongeumyo-bang" was complied in 682 by Son Sa-mak. As well as "CheongeumYo-bang" it doesn't make clear the sources of quotation from "Sanbeon-bang". So it used as the data for confirmation. "Oedaebiyo-bang" was compiled in 752 of Dang-Dynasty by Wang Do(王燾) the a governor-general of Eop-gun. Wang Do was descended from a noble family, and usually visited the palace and dealed with large number of books in Hongmunguan(弘文館), the national library. He programmed the book on the base of wide scopic collection of medical documents. And he took charge of gverment post at the same time as Wang Bing(王氷) who compiled "Chaju-Hwangje-Naegyeong-Somun(次注黃帝內經素問)" in 762. So we can guess they might have seen the same documents and holded the medical knowledge in common. The 40 volume "Oedaebiyo-bang" was a great medical complete book in those days. In particular, it became the model of medical complete books of after ages. The description of the book is mostly the qutation of medical documents of before ages. The character is recording of quotation documents and the order of volume. On the base of the recording, we can reconstruct the table of contents of Sanbeon-bang. By way of the contens, we can understand the purpose of "Sanbeon-bang". Besides, I can see a lot of qouotations of "Sanbeon-bang" in "Cheongeum-bang" and "Uisim-bang" are repeatedly quotated in "Oedaebiyo-bang". For that reason, I observed the bibliographical results of "Oedaebiyo-bang" in detail. "Uisim-bang" was compiled in 982 by the Japanese Niwayasyori(丹波綱賴). It followed the example of the structure of "Oedaebiyo-bang", refered to the contents of "Cheongeumyo-bang", collected chinese medical classic books spreaded in Japan. It contains medical documents of before Su-Dang(隋唐)-era, indicated the source of quotation. The importance of the book is summarization and preservation of large quantity of chinese medicine before 10th century. In this study, a lot of the quotation in "Uisim-bang" from "Sanbeon-bang" were not in "Oedaebiyo-bang".

• Journal of Korean Library and Information Science Society
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• v.51 no.3
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• pp.171-196
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• 2020

This study examined the development of the children's reading movement, focusing on the children's library establishment movement and reading guidance theory published in the Dong-A Ilbo and Chosun Ilbo in the 1920s and 30s. This paper analyzed the following contents. First, this study explored the background meaning that emphasized children's reading in the 1920s and 30s and discussions on the establishment of a children's library. In the process, this study examined the relationship between the national movement during the Japanese colonial period and children's education, and the meaning of reading at the time. Second, in this study, the development of children's library movement that was actively developed at the time and a methodology of reading education presented through the reading section were reviewed. It was this period that everyone was more interested in children's reading education than ever before. In addition, as the children's library movement was actively developed, a number of "Sonyeon Mungo" was established in various places. Meanwhile, in the reading section of the newspaper, a number of teaching methods for reading at school and at home were published, and examples were presented through advanced overseas reading education model. From the results of this analysis, it can be seen that the 1920s and 30s were the period when the children's reading movement was actively developed.

• Journal of Ecology and Environment
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• v.41 no.12
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• pp.328-335
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• 2017

Background: Some researchers have attempted to evaluate the ecological function of various additional services, away from the main point of view on the timber production of Korean forests. However, basic data, evaluation models, or studies on the absorption of air pollutants related to major plant communities in Korea are very rare. Therefore, we evaluated the functional value of the forest ecosystem in Gongju-city. Plantation manual for air purification, supplied from the Ministry of Environment in Japan, was referred to process and method for assessment of air pollutant absorption. Results: Gross primary production was calculated about average 18.2 t/ha/year. It was a relatively low value in forests mixed with deciduous broad and evergreen coniferous compared to pure coniferous forest. Net primary production was the highest value in deciduous coniferous and was the lowest value in mixed forest with deciduous broad and evergreen broad. And the mean sequestration amount of each air pollutant per unit area per year assessed from gross primary production and concentration of gas was the highest with 75.81 kg/ha/year in $O_3$ and was 16.87 and 6.04 kg/ha/year in $NO_2$ and $SO_2$, respectively. In addition, total amounts of $CO_2$ absorption and $O_2$ production were 716,045 t $CO_2$/year and 520,760 t $O_2$/year in all forest vegetation in Gongju-city. Conclusions: In this study, we evaluated the absorption ability of air pollutant in 2014 on forest in Gongju-city area. Gongju-city has the broad mountain area about 70.3%, and area of deciduous broad leaves forest was established the broadest with 47.4% of genus Quercus. Pg was calculated about average 18.2 t/ha/year. The mean sequestration amount of each air pollutant per unit area per year assessed from Pg and $C_{gas}$ was the highest with 75.81 kg/ha/year in $O_3$ and were 16.87 and 6.04 kg/ha/year in $NO_2$ and $SO_2$, respectively. Absorption rates of $O_3$, $NO_2$, and $SO_2$ were the highest in evergreen coniferous forest about $14.87kgO_3/ha/year$, $3.30kgNO_2/ha/year$, $1.18kgSO_2/ha/year$, and the lowest were $5.95kgO_3/ha/year$, $1.32kgNO_2/ha/year$, and $0.47kgSO_2/ha/year$ in deciduous broad forest. In conclusion, it was evaluated that Japanese model is suitable for estimating air pollutants in Japan to Korean vegetation. However, in Korea, there is a very limited basic data needed to assess the ability of forests to absorption of air pollutants. In this study, the accuracy of a calculated value is not high because the basic data of trees with similar life form are used in evaluation.

• The Journal of Natural Sciences
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• v.14 no.1
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• pp.123-138
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• 2004

This study was to investigate the planting arrangement of ornamental trees and shrubs that leads to an appropriate, type of templescape. Temples sampled for this study were Woljonsa, Sineunsa, Sinreugsa and Mitasa which fall all under the category of the level land. The results obtained were as follows : Open space of Daewoongjeon in all temples, a main Sanctuary among temple buildings, where Buddha is enshrined in, we could not find any kinds of trees/shrubs to be planted. But tere were Acer mono, Acer planmatum, Crataegus pinnatifidam Raododendron poukhanense, Texus cuspidata and Buxus mincrophylla to be planted, before Jeokkwangjeon, in which Buddha is exceptionally enshrined. In Geugragjeon of both temples of Sinheunsa and Sinreugsa, and Elysium building and Muryangsujeon of Woljeongsa temple, an immeasurable bliss building, in which an Amitabha is enshrined. was Taxus cuspidata planted numerously found. Particularly, Josadang, Muryangsujeon and Samsungkag of Woljeongsa temple commonly had Sciadopiys verticillata, which is known as one of Japanese-favorite trees. Syinga oblata Lindaley was also observed at Jeokkwangjeon of Woljeongsa temple and Keungnakjon of Sinheungsa temple, and Vidurnun opulus var. calvesvens, a symbolic flower tree imaging Buddha's head, was planted in Myungboojeon of Sinheungsa temple and Keugnakjeon of Sinreugsa temple. Juniperus chinensis which could be observed in both temples Sinheunsa and Sinreugsa was well arranged enough to be easily captured by human's eyes. In terms of templescape that might be considered in templescape, the correlation between trees/shrubs and temple buildings was thoroughly discussed. And, with the results obtained through precise studies, we presented here in this paper newly designed model of templescape in level land buddhist temples which is possibly applied for planting and arrangement of trees or/and shrubs.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.645-647
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• 2015

We have initiated a Very Long Baseline Interferometer (VLBI) monitoring project of 36 methanol maser sources at 6.7 GHz using the Japanese VLBI Network (JVN) and East-Asian VLBI Network (EAVN), starting in August 2010. The purpose of this project is to systematically reveal 3-dimensional (3-D) kine-matics of rotating disks around forming high-mass protostars. As an initial result, we present proper mo- tion detections for two methanol maser sources showing an elliptical spatial morphology, G 002.53+00.19 and G 006.79-00.25, which could be the best candidates associated with the disk. The detected proper motions indicate a simple rotation in G 002.53+00.19 and rotation with expansion in G 006.79-00.25, respectively, on the basis of disk model fits with rotating and expanding components. The expanding motions might be caused by the magnetic-centrifugal wind on the disk.