• 제목/요약/키워드: JAIN

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Bertolotti Syndrome: A Diagnostic and Management Dilemma for Pain Physicians

  • Jain, Anuj;Agarwal, Anil;Jain, Suruchi;Shamshery, Chetna
    • The Korean Journal of Pain
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    • 제26권4호
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    • pp.368-373
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    • 2013
  • Background: Bertolotti's syndrome (BS), a form of lumbago in lumbosacral transitional vertebrae, is an important cause of low back pain in young patients. The purpose of this study was to assess the etiology of low back pain and the efficacy of treatment offered to patients with BS. Methods: All patients of BS Castellvi type1a during a period of 6 months were enrolled in the study. The patients underwent interventional pain procedures for diagnosis and pain relief. Response to the therapy was assessed based on VAS and ODI scores. A 50% decrease in VAS score or a VAS score less than 3 would be considered adequate pain relief. Results: All 20 patients diagnosed with BS during the 6-month observation period had scoliosis. Common causes of back pain were the ipsilateral L5-S1 facet joint, neoarticulation, the SI joint, and disc degeneration. Responses to various interventions for pain relief were different and inconsistent from patient to patient. In particular, responses to interventions for neoarticular pain were generally poor. Conclusions: Pain in patients with BS does not usually respond to interventional pain treatment. A very dynamic treatment approach must be pursued while managing BS patients, and the treatment plan must be individualized at various stages in order to obtain satisfactory pain relief.

An in silico Appraisal to Identify High Affinity Anti-Apoptotic Synthetic Tetrapeptide Inhibitors Targeting the Mammalian Caspase 3 Enzyme

  • Kelotra, Seema;Jain, Meeta;Kelotra, Ankit;Jain, Ish;Bandaru, Srinivas;Nayarisseri, Anuraj;Bidwai, Anil
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권23호
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    • pp.10137-10142
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    • 2015
  • Apoptosis is a general phenomenon of all multicellular organisms and caspases form a group of important proteins central to suicide of cells. Pathologies like cancer, Myocardial infarction, Stroke, Sepsis, Alzheimer's, Psoriasis, Parkinson and Huntington diseases are often associated with change in caspase 3 mediated apoptosis and therefore, caspases may serve as potential inhibitory targets for drug development. In the present study, two series of synthetic acetylated tetrapeptides containing aldehyde and fluromethyl keto groups respectively at the C terminus were proposed. All these compounds were evaluated for binding affinity against caspase 3 structure. In series 1 compound Ac-DEHD-CHO demonstrated appreciable and high binding affinity (Rerank Score: -138.899) against caspase 3. While in series 2 it was Ac-WEVD-FMK which showed higher binding affinity (Rerank Score: -139.317). Further these two compounds met ADMET properties and demonstrated to be non-toxic.

과체중.비만 소아에 대한 한방비만치료프로그램 효과 (The Effect of Management Program of Oriental Medicine for Obesity Control on Overweight and Obese Pediatrics)

  • 이윤재;류은경
    • 한방비만학회지
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    • 제9권1호
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    • pp.45-51
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    • 2009
  • Objectives The purpose of this study was to investigate the effect of oriental treatment on pediatric overweight and obesity. Methods From the December 2006 to the May 2008, 19 children were treated of obesity control in J Korean Hospital, electrolipolysis, auricular acupuncture was done 2 times per week for 4 weeks with the consulting of diet and exercise. Nine children were treated for 9 weeks. We checked the change of weight at treatment time and the body composition measured by bioelectrical impedance analysis(BIA) per 2 weeks. Results After 4 weeks treatment, the weight loss was 2.67${\pm}$1.75kg. And after 9 weeks treatment, the weight loss of 9 children was 5.91${\pm}$2.73kg. Total fat mass measured by BIA significantly decreased 2.38${\pm}$1.19kg after 4 weeks. BMI and the weight loss of children were significantly correlated. After 4 weeks treatment the BMI significantly decreased 1.43${\pm}$0.89kg/m$^2$. After 8 weeks treatment the BMI of 9 children significantly decreased 3.31${\pm}$1.47kg/m$^2$. Conclusions The pediatric obesity could be effective treated by herdal medicine and electroacupuncture.

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한방비만프로그램의 체중감량 경과 관찰 (The Change of Weight Loss of Oriental Obesity Treatment)

  • 이윤재;류은경
    • 한방비만학회지
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    • 제9권1호
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    • pp.53-58
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    • 2009
  • Objectives The purpose of this study was to investigate the clinical effect of oriental medical therapy on obesity and the progress of weight loss through an oriental obesity program. Methods The subjects were treated from January 2008 to February 2009 in J Korean Medical Hospital. Herbal medical Hospital. Herbal medicine, electrolipolysis, auricular acupuncture were performed during the treatment period. We checked the change of weight every treatment time and measured the body composition by bioelectrical impedance analysis(BIA) every 2 weeks. Results The progress of weight loss was steady in the first 4 weeks except for the sixth weight check. After 4 weeks treatment, the weight loss was 3.52${\pm}$1.98Kg and 4.83${\pm}$2.68%. Total fat mass measured by BIA significantly decreased 2.58${\pm}$1.30Kg after 4 weeks. Age and the weight loss were significantly negative correlated. Conclusions Oriental obesity treatment could be effective on obesity, but further studies would be needed for the foundation of a clinical guideline reflecting various factors.

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5G Cloud RAN에서 네트워크 공평성 향상을 위한 계층적 적응 스펙트럼 관리 방법 (Hierarchical Dynamic Spectrum Management for Providing Network-wise Fairness in 5G Cloud RAN)

  • 조오현
    • 융합정보논문지
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    • 제10권7호
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    • pp.1-6
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    • 2020
  • 본 논문에서는 셀 간 정보의 공유를 통한 협력이 가능한 연결된 네트워크 구조를 갖는 5G Cloud RAN 네트워크에 적용이 가능한 새로운 자원 관리 알고리즘을 제안한다. 제안 알고리즘은 네트워크 협력의 이점을 활용하여 공정성과 처리량을 동시에 증가시킨다. 이러한 네트워크 성능 최적화는 허용이 가능한 양의 신호 처리 오버헤드 및 계산 복잡도 내에서 달성될 수 있으며 시뮬레이션 결과는 셀 외곽 사용자에 대한 네트워크 용량이 기존의 방법 대비 40% 가량 향상되었으며 사용자간 공정성 또한 Jain의 공평성 지수를 기준으로 약 23% 향상되었음을 확인하였다.

Impact of Selling, General and Administrative Expenses on Financial Sustainability of IT Companies Listed in S&P 500

  • Seetharaman, Seetharaman;Pitta, Santhikumar;Moorthy, Krishna;Saravanan, Saravanan
    • 유통과학연구
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    • 제14권4호
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    • pp.13-20
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    • 2016
  • Purpose - This paper attempts to determine the importance of financial sustainability and the impact of Selling, General and Administrative Expenses (SG&A) on the financial sustainability of the IT industry. Research design, data, and methodology - Primarily the impact of SG&A expenditure on the sales revenue, assets, gross margins and profit is ascertained. After that the impact of SG&A expenditure, sales revenue, assets, gross margins and profit on the financial sustainability i.e., return on assets is worked out. Finally the impacts of financial sustainability i.e., return on assets on total enterprise value and market valuation multiples are found out. Results - The empirical result shows that SG&A expenditure most strongly impacted sales revenue, assets, gross margins and profit positively. Financial sustainability impacted in mixed manner with SG&A expenditure, sales revenue, assets, gross margins and profit. Assets and gross margins have weak positive impact on financial sustainability. Sales revenue has no impact on financial sustainability. Finally financial sustainability had moderate positive impact on total enterprise value and had no impact on market valuation multiples. Conclusions - SG&A expense has moderate positive impact on the financial sustainability and magnitude is very low.

자인단오제 큰굿의 구조 정립 모색 (Seeking an Establishment of Structure in the Big-gut, Jaindanoje)

  • 홍태한
    • 공연문화연구
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    • 제19호
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    • pp.35-60
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    • 2009
  • 이 글은 현재 연행되고 있는 자인단오제의 큰굿의 구조에 문제가 있음을 지적하면서 구조를 새롭게 정립해야 함을 주장한 글이다. 현재 자인단오제에는 큰굿이 연행되고 있으나, 굿거리와 공연물이 복합적으로 얽혀 있어 굿거리의 성격이 모호하다. 그러다보니 한국 무속의 구조에 맞지 않은 이상한 굿거리들이 연행되고 있는데, 패왕별희, 어우동 거리 등이 그 예이다. 세부적인 절차도 어색하여 지역의 특색을 드러내기보다는 우리나라 각 지역의 무속 양상이 혼합되어 있다. 바라를 팔다가 고를 푸는 칠성거리가 그 예이다. 또한 개별 굿거리에 다수의 무당이 등장하여 춤을 추면서 굿을 연행하고 있어 굿이라기 보다는 무용극 내지는 춤공연으로 보이는 것도 문제이다. 이러한 문제점이 극복되어야 큰굿은 우리의 소중한 문화 자산이 될 수 있다. 따라서 한국굿의 구조를 고려할 때 초반부, 중반부, 종반부의 구성을 지키면서 굿거리의 층위를 신령의 체계와 맞출 필요가 있다. 굿거리가 아닌 것들은 과감하게 빼버려서 굿거리 중심의 연행물이 되어야 한다. 개별 굿거리를 담당하는 주무를 설정하고 주무 중심으로 굿을 진행해야 한다. 현재 담당하고 있는 이들이 문제가 있다면 경상도 내륙의 무속 사정을 잘 아는 새로운 연행담당층을 모색하는 것도 한 방법이 된다. 자인단오제 큰굿은 이제 무형문화재의 일부이다. 과거처럼 사람들의 흥미에 부응하고 호기심의 대상이 되는 공연물이 아닌 우리의 전통 문화를 대표하는 전승물이 되어야 한다. 지금까지 연행된 굿거리를 재검토하여 획기적으로 다시 재편해야 할 시점에 와있다.

A Simple and Clean Synthesis of Polysubstituted 2,6-Dicyanoanilines Catalyzed by KF/alumina

  • Jain, Shubha;Keshwal, Balwant S.;Rajguru, Deepika;Bhagwat, Vasant W.
    • 대한화학회지
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    • 제56권6호
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    • pp.712-715
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    • 2012
  • A simple and clean synthesis of polysubstituted 2,6-dicyanoanilines has been developed via the reaction of arylidenemalonodinitriles with 1-arylethylidenemalonodinitriles in ethanol catalyzed by KF/alumina. Use of non-hazardous solid base as a catalyst, operational simplicity and improved product yields are the key advantages of the present protocol.

SEM-COMPATIBILITY AND FIXED POINT THEOREM IN MENGER SPACE

  • Singh, Bijendra;Jain, Shishir
    • 충청수학회지
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    • 제17권1호
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    • pp.1-17
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    • 2004
  • In this paper, the concept of semi-compatibility in Menger space is introduced and it is used to prove results on the existence of a unique common fixed point of four self-maps. These results are a very wide improvement of Mishra [8], Dedeic and Sarapa [3, 4], Cain and Kasril [1], and Sehgal and Bharucha Reid [10].

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