• KSBB Journal
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• v.23 no.3
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• pp.219-225
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• 2008

For the production of an antifungal compound, one strain (I-8) was selected from approximately 400 strains isolated from various soil samples. The optimum carbon source, nitrogen source and pH culture conditions for the production of the antifungal compound were investigated. ISP No. 2 medium (yeast extract 0.4%, malt extract 1% and dextrose 0.4%, at pH 8) was determined to be the optimum medium. Strain I-8 showed broad antifungal activity against the plant pathogenic fungi tested, including Sclerotinia sclerotiorum KACC 41065, as well as cellulase and chitinase activities in an agar plate assay. The extraction of antifungal compounds was performed using ethyl ether and ethyl acetate. In a culture broth of strain I-8, the ethyl acetate extract exhibited effective growth inhibition against 14 of the 20 phytopathogenic fungi tested. By mixing the ethyl acetate extract from I-8 with the ethyl ether extract from the fungus 13-16, which shows specific antifungal activity against Colletotrichum orbiculare KACC 40808, the antifungal activity of I-8 against phytopathogenic fungi was confirmed to be slightly increased. Strain I-8 showed strong growth inhibition against 16 phytopathogenic strains in agar plate tests.

• Biomolecules & Therapeutics
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• v.5 no.2
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• pp.215-221
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• 1997

In an effort to screen new selective antitumor agents from the broth of soil microorganism, cytotoxicity oriented screening was performed against tumor cells and 3 compounds (Compound 1, 2 and 3) were isolated from Sreptomyces parvullus ISP 5048 and their chemical structures were determined. Among these compounds, Compound 2 showed the highest cytotoxicity against P388Dl and L1210. While the $IC_{50}$/ values of compound 2 against P388Dl and L1210 were 0.073$\mu$g/ml and 0.07$\mu$g/ml, respectively, and the $IC_{50}$/ value of Compound 3 was 0.17$\mu$g/ml against human lung cancer cells, A549, the cytotoxicity of Compound 2 and 3 against normal cell line, Vero E6 cell was about 4- and 8-fold lower than that of adriamycin. Based on the chemical analysis data, Compound 3 was octacosamicine A, a known antibiotic, which was reported by Dobasih et al. (1988). Taken together the results demonstrated that Compound 2 and Compound 3 has the possibility to be developed as antitumor agent because of its potent cytotoxicity as well as high selectivity against various cancer cell lines.

• Journal of Microbiology and Biotechnology
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• v.10 no.4
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• pp.535-538
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• 2000

Streptomyces lavendulae FRI-5 produces the ${\gamma}$-butyrolactone autoregulator IM-2, which is required for nucleoside antibiotic producetion. We have developed a system for introducing DNA into S. lavendule FRI-5 via conjugal transfer from Esherichia cole. Conditions were established for conjugation of the oriT-and attP-containing plasmid pSET152 from E. coli ET12567 (pUZ8002) to FRI-5. Conjugation resulted in integration of the plasmid at the chromosomal C31 attB site. The frequency of intergeneric conjugation varied with the medium used. The highest frequency ($1.6\times10-5$ per recipient) was obtained on ISP medium 2 containing 10mM MgCl2. Southern blot and phenotypic analyses of exconjugants revealed that S. lavendulae FRI-5 contains a unique C31 attB site, and that integration of heterologous DNA into the attB site did not interfere with morphological differentiation or IM-2-dependent signal transduction, including the production of a blue pigment. This system will now enable detailed genetic analysis of the regulation of antibiotic production in S. lavendulae FRI-5.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.1
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• pp.21-28
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• 2009

In this paper, we consider the Femtocell based enterprise wireless network using 2G/3G/4G cellular network technologies. And, we apply the open network service API which enable an easy development of ISP or enterprise services to P2P enterprise services. Based on the proposed scheme, enterprise services can be always connected at anywhere and anytime via heterogeneous devices. By using a qualitative analysis, we evaluate the performance of the proposed scheme and compare with that of the famous P2P service - Skype. Results show that the proposed scheme requests smaller servers and flows with enhanced service quality.

• Electronics and Telecommunications Trends
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• v.16 no.2 s.68
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• pp.10-30
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• 2001

본 고에서는 차세대 인터넷 구축을 위한 요소 기술에 대하여 전반적으로 살펴본다. 우리는 현재보다 1,000배 빠른 차세대 인터넷의 구축을 목표로 하고 있다. 따라서 과연 그만큼 빠른 인터넷의 구축이 필요할 것인가를 검증하는 차원에서 향후 5년 정도의 가까운 시일 내에 있을 인터넷 트래픽의 증대에 대한 수요를 서비스 측면에서 살펴본다. 차세대 인터넷은 풍부한 전송대역폭의 제공과 QoS를 기반으로 한 신뢰성 있는 데이터의 전달을 특징으로 하며, 이를 위해서 광스위칭 기반의 전송 하부구조 위에 MPLS 기술이 사용될 것으로 예상된다. 이를 위한 요소기술로 DWDM 전송기술, MEMS 기반의 광스위칭 소자기술과 함께 광스위칭 기술에 지능을 부여하기 위한 표준화 동향에 대하여 살펴본다. 현재의 IP 기반 인터넷에서 제공하지 못하는 QoS 기능은 MPLS에서 가능하게 될 것이다. MPLS에서의 중요한 응용인 트래픽 엔지니어링과 VPN 서비스는 망이 보다 안정적으로 유지될 수 있도록 지원하면서 기업들이 MPLS 망을 이용하여 자신의 망을 구축할 수 있도록 지원할 것이다. MPLS 기술은 IETF에서 표준화가 진행되고 있으며 라우터 개발업체 및 ISP의 큰 지원을 받고 있다. 차세대 인터넷을 위해서는 전달망의 구축도 필요하지만 이와 함께 차세대 인터넷 응용을 위한 컴퓨팅 인프라도 균형있게 개발되어야 한다. 따라서 현재 그 윤곽을 드러내고 있는 차세대 인터넷 응용 인프라 환경에 대하여 그 등장 배경과 관련 기술에 대하여 조망한다. 차세대 인터넷의 개발을 위해서는 광처리 관련 원천 기술, 프로세서 개발 기술, 라우터 설계 기술 및 서버 개발 기술, 어플리케이션 기반 기술 및 사용자 인터페이스 기술들이 전략적으로 이음새 없이 매끄럽게 통합되어야 한다. 이러한 관점에서 필요한 요소기술들을 다수 보유하고 있는 ETRI의 역할은 매우 중요하리라 생각된다.

• Korean Journal of Digital Imaging in Medicine
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• v.7 no.1
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• pp.23-31
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• 2005

원격진료 홈네트워크 아파트 진료용 키오스크 모바일주치의 등으로 대표되는 U-헬스케어에 있어서 기초가 되는 것은 의료정보를 디지털화해서 전자적 자료의 형태로 저장 보관하고 이를 송 수신할 수 있는 기술이라고 할 수 있다. 우리나라의 경우, U-Korea 전략의 하나로 보건복지부가 주축이 되어 2005년 10월 현재 국가보건의료정보화계획(ISP)을 수립하기 위한 작업을 추진중에 있다. 여기서, 예컨대 임상병리검사소견이나 방사선촬영소견 등의 의료정보가 전자적 장치에 의해 디지털화 할 경우 디지털 의료정보가 되는 것이며, 이 가운데 특히 방사선촬영소견 등 방사선분야의 모든 촬영기록이 PACS시스템을 통해 기재되거나 저장 전송될 경우 이를 디지털 의료영상정보라고 할 수 있다. 그런데 오늘날 정보통신기술의 발달로 말미암아 디지털 의료영상정보를 포함한 디지털의료정보는 대량적으로 수집 저장되고 유통 내지 공동활용이 보편화되어 감에 따라 그 의료정보의 보호에 관한 문제가 중요한 이슈로 대두되고 있다. 결론적으로 말하자면, 이러한 디지털 의료영상정보가 전자의무기록(EMR) 형태로 저장 보관되는 경우 이는 전자의무기록에 관한 법률규정이 적용되어 법률적 보호를 받게 되며, 그 보호의 강도는 종래 오프라인 상의 의료정보 보호보다 한층 강화된 규정을 두고 있다. 이와 같은 흐름에 있어서 최근 정부가 국가보건의료정보화계획 수립과 함께 제정작업을 추진하고 있는 가칭 의료정보화촉진 및 개인정보보호에 관한 법률(안)은 시사점이 크다고 보기 때문에 소개하고자 한다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.1
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• pp.520-523
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• 2005

As the Internet business has been growing rapidly, Internet users or Internet service providers have requested stable service. Along with them, the protection of data such as the management of computer information system and the prevention of barriers has become an important element. This study has embodied the remote control system that manages the scattered resources and service using JMX (Java Management Extensions) in the mobile environment and it has also suggest the method of connecting it with the remote terminal. Through the system suggested in this study, system managers are able to manage the system safely through their own regardless of time and space with the aid of mobile phone.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.1003-1006
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• 2005

Demand of Auto Focus for Camera module is increased very fast in these days and will be adapted to most of mobile phones in next few years instead of traditional method, fixed focus. To make auto focus function, 2 kinds of solutions, VCM(Voice Coil Motor) and Piezo linear motor are normally used. In this paper, VCM which commercially strong candidate for Auto focus mechanism was investigated to verify principles are match up to the actual operation. Auto focus algorithm is different between 1 chip and 2 chip solution. Normally 2 chip is more complicate than the other. To have best performance on this function, hysteresis and depth of field(DOF) table should be optimized.

• The Transactions of the Korea Information Processing Society
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• v.7 no.11S
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• pp.3613-3622
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• 2000

This paper presents IPv6 evolution strategies toward Next Generation Internet. We define requirements for IPv6 transition, then propose the IPv6 evolution strategies by considering IPv4/1Pv6 interworking, IPv6 development items with superiority compared to foreign technologies, IPv6 network evolution strategy for operation and management in stages by new Internet site or ISPs. the policy for structure and allocation of production IPv6 addresses, and reinforcement methods of the international activities on IPv6 related areas.

• Journal of Korea Society of Industrial Information Systems
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• v.11 no.2
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• pp.9-17
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• 2006

Over the last couple of years, established Cumulus Pricing Scheme(CPS) has become an important research issue for efficiently charging differentiated internet services. This paper proposes the adjusted CPS technique that expressed information of over or under-use of resources in bandwidth. And, 1 propose CPS with respect to the six main pricing and charging conditions. Also, accumulation technique may indicate an information between specified charging and eventually requires to adapt the initial contract. So called red and green Cumulus Points(CP) are used to judge the behavior of customer. At this point, the actual resource consumption is described by function v(t) at time t.