• Title/Summary/Keyword: Irradiation Dose

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An Experimental Study on the Effect of Repeated Hyperthermia on the Radiation Injury (반복 온열료법이 방사선조사효과에 미치는 영향에 관한 실험적 연구)

  • Choi, Young-Hi;Park, Charn-Il;Han, Man-Chung
    • Radiation Oncology Journal
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    • v.2 no.1
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    • pp.1-9
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    • 1984
  • To evaluate the influence of prior heat treatment on the thermal enhancement of irradiation effect after hyperthermia, an experimental study was carried out using a total of 80 mice. Hyperthermia was carried out at $43^{\circ}C$ for 40 minutes and was repeated with various intervals. A single dose of 3,000 rad was delivered on skin of mouse tail immediately after the second hyperthermia. The skin changes of the irradiated mouse tail were observed from 7th to 35th post-irradiation days, and the skin scores were analyzed. The results are as follows, 1. The radiation damage on mouse skin increased significantly when radiation was combined with hyperthermia. 2. The radiation damage after repeated hyperthermia is significantly less than that after single hyperthermia, when the interval is 1 to 6 days. 3. As a result, thermal tolerance persists from 1 through 6 days after the initial hyperthermia.

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A Verification for Multiple Arc Stereotaxic Radiotherapy (정위 다방향 방사선조사의 선량분포를 위한 증명)

  • Yoon, Sei-Chul;Jang, Hong-Seok;Kim, In-Ah;Shinn, Kyung-Sub;Bahk, Yong-Whee
    • Radiation Oncology Journal
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    • v.8 no.1
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    • pp.111-114
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    • 1990
  • External stereotaxic irradiation of intracranial lesions has recently gained its interest in the fields of not only radiation oncolgy but also neurosurgery. Its main goal is to deliver large doses to a relatively small target volume. Authors present methods of the stereotaxic radiosurgical irradiation using 6 MV linear accelerator (Nelac-6) and isodose distribution by therapeutic computer (Therac 2000). We attempt to demonstrate the dose distribution on verification films.

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The effect of low energy laser irradiation on wound healing (저에너지 레이저 조사가 창상치유에 미치는 영향)

  • Han, Chang-su;Kim, Myung-cheol
    • Korean Journal of Veterinary Research
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    • v.37 no.3
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    • pp.629-637
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    • 1997
  • This study was performed to determine the optimal dose of laser energy for wound healing. The skin wound with 8mm diameter was induced over the lumbar vertebrae of the rats, and wound squares, scab hardness, hematologic findings and histopathlogic findings according to irradiation of laser energy were studied. 1. Wound square was significantly reduced at Day 1 (p<0.01), 2 (p<0.01), 3 (p<0.05), 7 (p<0.01) and 8 (p<0.05), respectively in experimental groups, especially group II, compared with control group. 2. Scab hardness was significantly increased at Day 1 (p<0.01), 2 (p<0.01), 3 (p<0.05), 5 (p<0.01) and 7 (p<0.01), respectively in experimental groups, especially group II, compared with control group. 3. In hematological findings, red blood cells and white blood cells in experimental group were increased according to the lapse of days, but they were not significant. 4. In histopathologic findings, experimental groups, especially group II, revealed early scab formation, early appearance of phagocytes and fibroblast, rapid growth of granulation tissue and collagen, and promotion of wound healing in the result.

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Application of Immunoassay for the Detection of Gamma-Irradiated Shrimp (감마선 조사된 새우의 검지를 위한 면역분석법의 적용)

  • 이주운;육홍선;조경환;차보숙;변명우
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.4
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    • pp.600-604
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    • 2001
  • Immunoassay was used to study the detection method of irradiated shrimp. Sandwich ELISA was formatted with monoclonal antibody (Ab) (M-IgG) and polyclonal Abs (P-IgG) and polyclonal Abs (P-IgG) individually produced against brown shrimp tropomyosin (TPM) as an antigen. When M-IgG was used as a coating Ab to capture TPM, and P-IgG were used as reaction Ab against captured TPM could be detected in the range of 12.5 to 50 $\mu\textrm{g}$/mL. Detected concentrations of TPM from irradiated shrimp decreased dose-dependently, and the concentration of Ag by combination of irradiation with heating or freezing treatments also decreased. This results suggests the possibility for Sandwich ELISA, one of immunological analyses, to be applied for detecting irradiated shrimp.

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Adhesion Properties of UV-curable Pressure Sensitive Adhesives for Dicing Tape (다이싱 테이프용 자외선 경화형 점착제의 접착 물성)

  • Do, Hyun-Sung;Kim, Sung-Eun;Kim, Hyun-Joong
    • Journal of Adhesion and Interface
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    • v.5 no.4
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    • pp.1-8
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    • 2004
  • UV-curable pressure sensitive adhesives were prepared by blending acrylic copolymer, copolymerized with butyl acrylate, acrylic acid and methyl methacrylate by solution polymerization, and trimethylolpropane triacrylate. The PSAs were evaluated by adhesion strength with varying UV dose, and also glass transition temperature ($T_g$) of PSAs were measured. When exposed on UV irradiation, the PSAs showed the decreased adhesion strength and increased $T_g$. And following UV irradiation, the PSAs did not leave any residue on wafer after peel off PSA.

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EXPERIMENTAL STUDY ON THE EFFECT OF RADIATION IN THE SECONDARY PALATE FORMATION. (방사선조사가 구강형성기에 미치는 영향에 관한 실험적 연구)

  • You Dong Soo
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.7 no.1
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    • pp.9-15
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    • 1977
  • The author observed the effect of X-ray irradiation on the secondary palate formation of the rat fetuses. The mothers were exposed to X-radiation on the 10½th, 11½th and 12½th day of gestation with respectively 150, 200, 250, 300 and 350 rads. The fetuses were removed from mothers on 15½h, 16½th and 18½th day of gestation. Morphological changes in palate formation were examined and histochemical preparations were made. 1. In control fetuses, the secondary palates were fully developed on the 15½th to 18½th day of gestation. But in experimental fetuses, many cleft palates were observed in accordance with increase of X-radiation dose. 2. Frequency of incidence of horizontal position of both palated shelves in cleft palate was highest. 3. Accordig to the dislocation of palatal processes, the stain ability of palatal crest was varied. 4. The thickened area of palatal epithelium of palatal crest showed intense methyl green-pyronin and PAS reaction 5. Mesenchymal cell condensation was appeared under the thickened epithelium of palatal process and this mesenchymal tissue showed strong colloidal iron reaction. 6. The stain ability of alizarin red S and alkaline phosphatase reaction of tectal ridge were decreased, in accordance with increase of irradiation doses.

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Measurements and Assessments on Shielding Performance of FCTC10 60Co Transport Container

  • Zhuang, Dajie;Zhang, Guoqing;Li, Guoqiang;Wang, Renze
    • Journal of Radiation Protection and Research
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    • v.41 no.3
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    • pp.310-314
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    • 2016
  • Background: FCTC10 container is designed to transport $^{60}Co$ radioactive sources used in irradiation industry. It belongs to Type B(U) Category III (yellow) package when being loaded with a $^{60}Co$ source of $1.8{\times}10^5$ Ci. Materials and Methods: The container is constituted of shielding container, basket, protective cover and bracket. Shielding ability is provided mainly by stainless steel shells, tungsten alloy and lead among steel shells. Radiation level around the container has been calculated with both Monte Carlo simulations and measurements. Results and Discussion: It is proven that the shielding performance of the container fulfills the requirements in GB11806-2004 (Regulations for the safe transport of radioactive material, China Standard Press). Exposure doses to workers and to critical groups of public were calculated based on hypothetical exposure scene according to transport practice experience. Conclusion: The results show that doses to workers and public are less than the constraint dose considered in design, and the radiation level would be increased less than a factor of 2 under design basis accidents.

A Case of Piroxicam-induced Phtosensitive dermatitis (Piroxicam에 의한 광과민성 피부염 1례)

  • Kim, Ki-Hong;Kim, Jong-Cheul;Park, Yong-Myo;Shin, Dong-Hoon;Choi, Jong-Soo
    • Journal of Yeungnam Medical Science
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    • v.8 no.1
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    • pp.215-219
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    • 1991
  • We report a case of piroxicam-induced photosensitive dermatitis in a 54-year-old female. She had taken oral piroxicam and was exposed to the sunlight on her way home for a few minutes. Several hours after the sun-exposure she developed well-defined, confluent, erythematous plaques and numerous vesicobullae with pruritus and prickling sensation on the sun-exposed areas. A phototest was done on her first visit. The minimal erythemogenic dose(2J/$cm^2$) of ultraviolet(UV) A was markedly decreased whereas that of UVB was within a normal limit. Visible light irradiation for 30 minutes did not cause skin lesions. Six months after the initial skin lesions, a photopatch test with 1% and 10% piroxicam solution followed by UVA(10J/$cm^2$) irradiation showed positive responses on both concentrations.

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AN EXPERIMENTAL STUDY OF THE IRRADIATION EFFECTS ON RAT SUBMANDIBULAR GLAND (방사선 조사가 백서 악하선조직에 미치는 영향에 관한 실험적 연구)

  • Lee Chang Hwan;Lee Sang Rae
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.20 no.1
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    • pp.139-148
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    • 1990
  • The purpose of this study was to investigate the effects of irradiation on the rat submandibular gland which composed of the epithelial growth factors. The experimental animals were the Sprague Dawley strain rats, which were the rats as the non-irradiated control group and the rats as the experimental group which were divided into groups as the experimental duration of 1 hour, 3 hours, 6 hours, 12 hours, 1 day, 3 days, 1 week, 2 weeks, 4 weeks. The experimental animals were singly irradiated at a dose of 8 Gray gamma ray to their head and neck region by the Co-60 teletherapy unit and sacrificed after each experimental duration. The specimens were stained with H-E and Azan stain and examined light microscopically. The results of this study were obtained as follows. 1. The all of mucous and serous acini in submandibular gland showed similar pattern of changes in structure according to the lapse of time. 2. The acinic cells started to change after 1 hour, and repaired after 12hours with mitosis and proliferation of the cells between acini. The changes were marked after 1day, and repaired gradually in course of time. 3. The duct were dilatated irregularly, and the outline of the eosinophilic stained ductal cells changed indistinctly.

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Thermal Properties of Chloroprene Rubber with $^{60}Co\;{\gamma}$-ray Irradiation ($^{60}Co\;{\gamma}$-선 조사에 따른 클로프렌 고무의 열적 특성)

  • Kim, Ki-Yup;Lee, Chung;Ryu, Boo-Hyung
    • Journal of the Korean Society of Safety
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    • v.18 no.4
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    • pp.64-70
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    • 2003
  • The thermal properties of chloroprene rubber (CR) with $^{60}Co\;{\gamma}$-ray irradiation has been investigated. The prepared CR was irradiated up to 1000kGy radiation dose by $^{60}Co\;{\gamma}$-ray and the radiation degradation of CR was investigated by thermogravimetric analysis and differential acanning calorimetry. Dynamic mechanical properties measurement and FT-IR observation are carried out as well. From these analyses results, the glass transition temperature($T_g$), decomposition onset temperature(DOT), oxidative induction time(OIT), the peak temperature of loss modulus and mechanical tan ${\delta}$ values were compared for the radiation degradation level of CR. The tendency between $T_g$ and peak temperature of loss modulus and mechanical tan ${\delta}$ agreed well with radiation doses. Decomposition temperature, OIT and DOT showed the same tendencies as increasing radiation doses. It was verified that these analyses are available to estimate the degradation level of CR.