A Case of Piroxicam-induced Phtosensitive dermatitis

Piroxicam에 의한 광과민성 피부염 1례

  • Kim, Ki-Hong (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Kim, Jong-Cheul (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Park, Yong-Myo (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Shin, Dong-Hoon (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Choi, Jong-Soo (Department of Dermatology, College of Medicine, Yeungnam University)
  • 김기홍 (영남대학교 의과대학 피부과학교실) ;
  • 김종철 (영남대학교 의과대학 피부과학교실) ;
  • 박용묘 (영남대학교 의과대학 피부과학교실) ;
  • 신동훈 (영남대학교 의과대학 피부과학교실) ;
  • 최종수 (영남대학교 의과대학 피부과학교실)
  • Published : 1991.06.30

Abstract

We report a case of piroxicam-induced photosensitive dermatitis in a 54-year-old female. She had taken oral piroxicam and was exposed to the sunlight on her way home for a few minutes. Several hours after the sun-exposure she developed well-defined, confluent, erythematous plaques and numerous vesicobullae with pruritus and prickling sensation on the sun-exposed areas. A phototest was done on her first visit. The minimal erythemogenic dose(2J/$cm^2$) of ultraviolet(UV) A was markedly decreased whereas that of UVB was within a normal limit. Visible light irradiation for 30 minutes did not cause skin lesions. Six months after the initial skin lesions, a photopatch test with 1% and 10% piroxicam solution followed by UVA(10J/$cm^2$) irradiation showed positive responses on both concentrations.

저자들은 54세 여자에서 piroxicam 복용 후 일광노출부위에 광과민성 피부염이 발생한예를 경험하고 광검사 및 광첩포검사 결과 광알레르기성 피부염으로 사료되는 예를 문헌고찰과 함께 보고하는 바이다.

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