• Asian Journal of Atmospheric Environment
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• v.8 no.3
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• pp.162-174
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• 2014

An abnormal decrease in ozonesonde sensor signal occurred during air-pollution study campaigns in November 2011 and March 2012 in Mexico City Metropolitan Area (MCMA). Sharp drops in sensor signal around 5 km above sea level and above were observed in November 2011, and a reduction of signal over a broad range of altitude was observed in the convective boundary layer in March 2012. Circumstantial evidence indicated that $SO_2$ gas interfered with the electrochemical concentration cell (ECC) ozone sensors in the ozonesonde and that this interference was the cause of the reduced sensor signal output. The sharp drops in November 2011 were attributed to the $SO_2$ plume from Popocat$\acute{e}$petl volcano southeast of MCMA. Experiments on the response of the ECC sensor to representative atmospheric trace gases showed that only $SO_2$ could cause the observed abrupt drops in sensor signal. The vertical profile of the plume reproduced by a Lagrangian particle diffusion simulation supported this finding. A near-ground reduction in the sensor signal in March 2012 was attributed to an $SO_2$ plume from the Tula industrial complex north-west of MCMA. Before and at the time of ozonesonde launch, intermittent high $SO_2$ concentrations were recorded at ground-level monitoring stations north of MCMA. The difference between the $O_3$ concentration measured by the ozonesonde and that recorded by a UV-based $O_3$ monitor was consistent with the $SO_2$ concentration recorded by a UV-based monitor on the ground. The vertical profiles of the plumes estimated by Lagrangian particle diffusion simulation agreed fairly well with the observed profile. Statistical analysis of the wind field in MCMA revealed that the effect Popocat$\acute{e}$petl was most likely to have occurred from June to October, whereas the effect of the industries north of MCMA, including the Tula complex, was predicted to occur throughout the year.

• Journal of Korean Neurosurgical Society
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• v.58 no.2
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• pp.150-154
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• 2015

Cerebral venous sinus thrombosis (CVST) following a closed head injury in pediatric patients is a rare condition, and an early spontaneous recanalization of this condition is extremely rare. A 10-year-old boy was admitted with a mild, intermittent headache and nausea five days after a bicycle accident. The brain computed tomography showed an epidural hematoma at the right occipital area with pneumocephalus due to a fracture of the occipital skull bone. The brain magnetic resonance imaging and the magnetic resonance venography demonstrated a flow signal loss from the right sigmoid sinus to the right jugular vein. The diagnosis was sigmoid sinus thrombosis, so close observations were selected as a treatment for the patient because of his gradually improving symptoms; however, he complained of vomiting 14 days the after conservative treatment. The patient was readmitted for a further examination of his symptoms. The laboratory and the gastroenterological examinations were normal. Due to concern regarding the worsening of the sigmoid sinus thrombosis, the brain magnetic resonance venography was rechecked and it revealed the recanalization of the venous flow in the sigmoid sinus and in the jugular vein.

• Journal of Positioning, Navigation, and Timing
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• v.9 no.3
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• pp.237-248
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• 2020

GNSS has been evolving dramatically in recent years. There are currently 6 GNSS (4 GNSS, AND 2 RNSS) constellations, which are GPS (USA), GLONASS (Russia), BeiDou (China), Galileo (EU), QZSS (Japan), and IRNSS (India). The Number of navigation satellites is expected to be over 150 by 2020. As the number of both constellations and satellites used for the improvement of positioning performance, high accuracy, and robustness of precise positioning is more promising. However, a large amount of the correction messages is required to support the augmentation system for the available satellites of all the constellations. Since bandwidth for the correction messages is generally limited, sending or scheduling the correction messages might be a critical issue in the near future. In this study, we analyze the relationship between the size of the bandwidth and Real-Time Kinematics (RTK) performance. Multiple Signal Messages (MSM), the only Radio Technical Commission for Maritimes (RTCM) message that supports multi-constellation GNSS, has been used for this assessment. Instead of the conventional method that broadcasts all the messages at the same time, we assign the MSM broadcasting interval for each constellation in 5 seconds. An open sky static and dynamic test for this study was conducted on the roof of Sejong University. Our results show that the RTK fixed position accuracy is not affected by the 5-second interval corrections, but the ambiguity fixing rate is degraded for poor DOP cases when RTK correction are transmitted intermittently.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2006.11a
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• pp.327-330
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• 2006

With the increasing requirements for the survey and development of the ocean, the demands on the of AUV(Autonomous Underwater Vehicle) technologies have been increased. Reconstruction and replay of the AUV motion on the basis of the data stored during the execution of mission, can help the development of control strategies for AUVs such as mission planning and control algorithms. While an AUV cruises for her mission, her attitude and position data are is recorded. The data can be used for visualization of the motion in off-line. However, because most of the position data gathered from acoustic sensors have long time-interval and include intermittent faulty signal, the replayed motion by the graphic simulator can not demonstrate the motion as a smooth movie. In this paper, interpolation methods are surveyed to reconstruct the AUV position data. Then, an efficient 3D visualization method for AUV motion using the interpolation method is proposed. Simulation results arc also included to verify the proposed method.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.9 no.4
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• pp.472-483
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• 1997

An experimental facility consisting of two $3{\times}4.4{\times}3.8m$ rooms identical in construction is built. Each room has a control system and storage tank supplying hot water to the radiant floor heating system. The facility enables simultaneous comparision of two different control stratigies each implemented in a separate room. The operating performance of three kinds of flow control scheme is tested and compared in this study : (i) conventional on-off control based on feedback from room air temperature (ii) TPSC(two parameter switching control) (iii) TPOC(two parameter on-off control). Results show that TPSC and TPOC using room air and surface temperature sequentially as feedback signal to control hot water supply is the better temperature regulation scheme than conventional control based on feedback from only room air temperature. They are good candidates for the room with radiant floor heating system under continuous and intermittent heating mode.

• Journal of Microbiology and Biotechnology
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• v.9 no.6
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• pp.811-819
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• 1999

The ${\beta}-CGTase$ gene of alkalophilic Bacillus firmus var. alkalophilus was cloned into E. coli using $pZErO^{TM}-2$ as a vector. The cloned gene encoded a total of 710 amino acid residues consisting of 674 amino acids of the matured protein and 36 amino acids of the signal peptide, including 20 amino acids from the lacZ gene in the vector. Although the cloned ${\beta}-CGTase$ gene did not contain the promoter and start codons, it was expressed by the lac promoter and lacZ start codon in the $pZErO^{TM}$ vector. A comparison was made with the amino acid sequence and ten other CGTases from Bacillus sp. Also, ten highly conserved regions, which are important amino acid residues in catalysis of CGTase, were identified. The lac promoter used for expression of the ${\beta}-CGTase$ gene was induced constitutively in recombinant E. coli even without IPTG possibly because of a lack of the lacI gene in both host and vector, repressing the lacZ gene in the lac operon. Its expression was catabolically repressed by glucose, however, its repression was reduced by soluble starch, mainly because of the extremely high increase of the cAMP level. ${\beta}-CGTase$ can be overproduced in the recombinant E. coli by maintaining intracellular cAMP levels mostly through the intermittent feeding of glucose during cultivation.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.21 no.1
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• pp.1-6
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• 1985

The underwater noise was measured by piezo-electric hydrophones submerged in the water at three different depths. The signals were led through connection cables to preamplifiers, and recorded simultaneously by a four channel tape recorder, and analysed by high resolution signal analyzer. The measurements were carried out at the fjord Skossvassen in archipelago off Bergen and at the cost of Norway in the North Sea. The results of the measurements and the analysis showed that the underwater noise consists of a steady broad band noise superposed by intermittent pulse of various strength. The noise levels measured in fjord Skossvassen indicated that they were generally higher at the shallow (10m) hydrophone than at the deeper hydrophone (25m, 50m). This tendency was not very distinct, however, the noise sources are close to the surface. The underwater noise spectrums measured in the open sea of Norway showed almost similar situation in all layers. This tendency showed that the noise sources are not close to the surface but they are far away from the measuring positions.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.47 no.2
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• pp.68-76
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• 2010

Touch-enabled technology is increasingly being accepted as a main communication interface between human and computers. However, conventional touchscreen technologies, such as resistive overlay, capacitive overlay, and SAW(Surface Acoustic Wave), are not cost-effective for large screens. As an alternative to the conventional methods, we introduce a newly emerging method, an optical imaging touchscreen which is much simpler and more cost-effective. Despite its attractive benefits, optical imaging touchscreen has to overcome some problems, such as heavy computational complexity, intermittent ghost points, and over-sensitivity, to be commercially used. Therefore, we designed a hardware controller for signal processing and multi-coordinate computation, and proposed Infrared-blocked DA(Dark Area) manipulation as a solution. While the entire optical touch control took 34ms with a 32-bit microprocessor, the designed hardware controller can manage 2 valid coordinates at 200fps and also reduce energy consumption of infrared diodes from 1.8Wh to 0.0072Wh.

• Biomolecules & Therapeutics
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• v.25 no.3
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• pp.239-248
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• 2017

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which is commonly explained by steric hindrance caused by the ${\beta}$-arrestins that are translocated to the activated receptors, molecular mechanisms involved in the acute tolerance of GPCRs remain unclear. Our studies with several GPCRs and related mutants showed that the acute tolerance of GPCRs could occur independently of agonist-induced ${\beta}$-arrestin translocation. A series of co-immunoprecipitation experiments revealed a correlation between receptor tolerance and interactions among receptors, ${\beta}$-arrestin2, and $G{\beta}{\gamma}$. $G{\beta}{\gamma}$ displayed a stable interaction with receptors and ${\beta}$-arrestin2 in cells expressing GPCRs that were prone to undergo tolerance compared to the GPCRs that were resistant to acute tolerance. Strengthening the interaction between $G{\beta}{\gamma}$ and ${\beta}$-arrestin rendered the GPCRs to acquire the tendency of acute tolerance. Overall, stable interaction between the receptor and $G{\beta}{\gamma}$ complex is required for the formation of a complex with ${\beta}$-arrestin, and determines the potential of a particular GPCR to undergo acute tolerance. Rather than turning off the signal, ${\beta}$-arrestins seem to contribute on continuous signaling when they are in the context of complex with receptor and $G{\beta}{\gamma}$.

• Investigative Magnetic Resonance Imaging
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• v.2 no.1
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• pp.14-30
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• 1998

Manganese is an essential element in the body. It is mainly deposited in the liver and to a lesser degree in the basal ganglia of the brain and eliminated through the bile duct. Rapid turnover of managanese in the body makes it difficult to evaluate the manganese exposure in workers, esecially in those with irregular or intermittent exposure, like welders. Therefore, conventional biomarkers, including blood and urine manganese can provide only a limited information about the long-tern or cumulative exposure to manganese. Introduction of magnetic resonance imaging (MRI) made a progress in the assessment of manganese exposure in the medical conditions related to manganese accumulation, e. g. hepatic failure and long-term total parenteral nutrition. Manganese shortens spin-lattice(T1) relaxation time on MRI due to its paramagnetic property, resulting in high signal intensity (HSI) on T1-weighted image(T1W1) of MRI. Manganese deposition in the brain, therefore, can be visualizedas an HSI in the globus pallidus, the substantia nigra, the putamen and the pituitary. clinical and epidemiologic studies regarding the MRI findings in the cases of occupational and non-occupational manganese exposure were reviewed. relationships between HSI on T1W1 of MRI and age, gender, occupational manganese exposure, and neurological dysfunction were analysed. Relationships betwen biological exposure indices and HSI on MRE werealso reviewed. Literatures were reviewed to establish the relationships between HSI, Manganese deposition in the brain, pathologic findings, and neurological dysfunction. HSI on T1W1 of MRI reflects regional manganese deposition in the brain. This relationship enables an estimation of regional manganese deposition in the brain by analysing MR signal intensity. Manganese deposition in the brain can induce a neuronal loss in the basal ganglia but functional abnormality is supposed to be related to the cumulative exposure of manganese in the brain, use of brain MRI for the assessment of exposure in a group of workers seems to be hardly rationalized, while ti can be a useful adjunct for the evaluation of manganese exposure int he cases with suspected manganese-related health problems.