• Fire Science and Engineering
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• v.33 no.1
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• pp.85-91
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• 2019

This study evaluated the fire detection performance of an automatic fire extinguishing system for road tunnels, which combines flame wavelength detection technology with flame image detection technology. This fusion technique to improve the fire detection capability can reduce the damage caused by the fire suppression by locating the fire source in the fire and discharging the pressurized water only at the fire source. Experiments were conducted to determine the position of a fire source when a $70cm{\times}70cm$ target was placed at a distance of 15 m, 20 m, 25 m, 30 m, and 35 m, respectively, in a situation where there is a flame and smoke in a tunnel. The performance of the ultraviolet and triple wavelength infrared (IR3) sensors was attenuated due to the interference of thick smoke. In addition when the flame was blocked by thick smoke, the image sensor sensed the smoke and emitted a fire signal.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.4
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• pp.617-624
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• 2021

The accurate estimation of the number of signals included in the received signal is required for the AOA(: Angle-of-Arrival) estimation, the interference suppression, the signal reception, etc. AIC(: Akaike Information Criterion) and MDL(: Minimum Description Length) algorithms, which are known as the typical algorithms to estimate the signal number, estimate the number of signals according to the minimum of each criterion. As the number of antenna elements increased, the estimation performance is enhanced, but the computational complexity is increased because values of criteria for entire antenna elements should be calculated for finding their minimum. In order to improve this problem, in this paper, we propose AIC and MDL algorithms based on the beamspace, which efficiently estimate the number of signals while reducing the computational complexity by reducing the dimension of an array antenna through the beamspace processing. In addition, we provide computer simulation results based on various scenarios for evaluating and analysing the estimation performance of the proposed algorithms.

• Journal of Korea Society of Industrial Information Systems
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• v.27 no.5
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• pp.49-59
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• 2022

The SHAPE algorithm has the advantage of being able to shape the pulse spectrum as desired and design it not to distort other characteristics, so it was used in the active sonar pulse design. In this paper, we propose a pulse design using the SHAPE algorithm for a multi-static sonar system to reduce the cross-correlation between frequency-adjacent pulses and prevent the performance degradation of the pulses themselves. The boundary function of the SHAPE algorithm is set to be limited to the pulse bandwidth. As a result of applying the proposed design method to the sinusoidal frequency modulated pulse, the peak cross-correlation level (PCCL), which means the degree of cross-correlation, was reduced by 44.23 dB. Although the PCCL decreased by several tens of dB, no significant change in the ambiguity function was observed, and the integrated sidelobe level (ISL), which means the average value of the side lobe, increased by 11.64 dB.

• The Korean Journal of Malacology
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• v.30 no.2
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• pp.155-163
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• 2014

Serpins are a group of proteins involved in the regulation of serine and other type of proteases, and have been identified in many kinds of organisms from invertebrates to vertebrates. Serpins are known to regulate the proteolytic cascades of the innate immune pathways in addition to their roles in blood coagulation, angiogenesis, fibrinolysis, inflammation and tumor suppression. In this study, we have isolated two partial serpin gene fragments from expressed sequence tags (ESTs) of Nesiohelix samarangae. Dotplot analysis indicates that they are of two different types, Ns-serpin type 1 and Ns-serpin type 2. Ns-serpin type 1 has 819 bp coding region (272 amino acids), whereas Ns-serpin type 2 has 555 bp coding region (185 amino acids). Molecular phylogenetic analysis shows that the identified serpins have high similarities to their counterparts in the California see slug, Aplysia californica. Yet, the precise biological and immunological roles of these Ns-serpins remain to be further investigated using RNA interference and other molecular techniques.

• Analytical Science and Technology
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• v.16 no.5
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• pp.391-398
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• 2003

Basic research for the determination of boron content in biological sample has been carried out using the PGAA facility of the 24MW research reactor(HANARO). For investigation of characteristics for the measurement condition, neutron flux and its homogeneity were measured at irradiating geometry. The size of thermal neutron beam collimated from beam guide is $2{\times}2cm^2$ at the sample position. The neutron flux measured was the range of $1.0{\sim}6.5{\times}10^7n{\cdot}cm^{-2}{\cdot}s^{-1}$, and flux distribution from center within the radius of 4.5 mm and 9.0 mm was $5.77{\pm}0.71{\times}10^7n{\cdot}cm^{-2}{\cdot}s^{-1}$ and $4.68{\pm}1.64{\times}10^7n{\cdot}cm^{-2}{\cdot}s^{-1}$, respectively. Accordingly, sample size is adjusted within 10 mm for a homogeneous irradiation of high quality. Measurement system is designed to reduce the background source by Compton scattering and to improve the analytical sensitivity. To investigate the energy calibration and Compton suppression effect of gamma-ray counting system, the background conditions on both of Compton and single-mode were measured using NaCl standard. On the other hand, degree of spectral interference for sodium 472 keV peak as a matrix effect in the sample is established for an accurate boron analysis, and then boron content in three certified reference materials (NIST SRM 1570a, 1547, 1573a) was measured by using two modes and the results were compared with each other.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.10
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• pp.1089-1097
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• 2002

In this paper, the novel shipboard Active Phased Array Antenna(APAA) system for maritime mobile satellite communications is introduced. The antenna uses novel technologies like wide range hybrid tracking, single antenna elements with both of Rx and Tx, asymmetrical array structure, interference isolation between Rx and Tx, and error correction method from frequency scan effect. The antenna has single aperture for both of Rx and Tx with 32 $\times$ 4 two-dimensional array. The antenna has two beams. Its frequencies are 7.25 ~ 7.75 GHz for Rx and 7.9 ~ 8.4 GHz for Tx. The antenna gains are 35.4 dBi for Rx and 35.7 dBi for Tx, those are 54 % of efficiency. The electrically steering ranges are $\pm$35$^{\circ}$ of elevation direction and $\pm$4$^{\circ}$ of azimuth direction. The mechanical control ranges at hybrid tracking capability are continuous 360$^{\circ}$ of azimuth direction and $\pm$10$^{\circ}$ of elevation direction. The antenna has 2.2$^{\circ}$ of 3 dB beamwidth, -14 dB of sidelobe level, and 21 dB of cross-pol suppression. The antenna performance was measured by near field measurement set. Its system performance was tested on the ship motion simulator and with the satellite transponder simulator. The test result showed that its tracking error was within -3 dB from its peak gain under motion condition. The antenna system was tested by real modulated Direct Broadcasting Satellite(DBS) signals to check its communication processing function.

• Molecules and Cells
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• v.43 no.7
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• pp.619-631
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• 2020

In this study, we describe a novel function of TNNC1 (Troponin C1, Slow Skeletal and Cardiac Type), a component of actin-bound troponin, as a tumor suppressor of lung adenocarcinoma (LUAD). First, the expression of TNNC1 was strongly down-regulated in cancer tissues compared to matched normal lung tissues, and down-regulation of TNNC1 was shown to be strongly correlated with increased mortality among LUAD patients. Interestingly, TNNC1 expression was enhanced by suppression of KRAS, and ectopic expression of TNNC1 in turn inhibited KRAS^G12D-mediated anchorage independent growth of NIH3T3 cells. Consistently, activation of KRAS pathway in LUAD patients was shown to be strongly correlated with down-regulation of TNNC1. In addition, ectopic expression of TNNC1 inhibited colony formation of multiple LUAD cell lines and induced DNA damage, cell cycle arrest and ultimately apoptosis. We further examined potential correlations between expression levels of TNNC1 and various clinical parameters and found that low-level expression is significantly associated with invasiveness of the tumor. Indeed, RNA interference-mediated down-regulation of TNNC1 led to significant enhancement of invasiveness in vitro. Collectively, our data indicate that TNNC1 has a novel function as a tumor suppressor and is targeted for down-regulation by KRAS pathway during the carcinogenesis of LUAD.

• Journal of Ocean Engineering and Technology
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• v.33 no.4
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• pp.350-357
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• 2019

The development of marine technology is expected to increase the demand for marine plants because of increasing oil prices. Therefore, there is also expected to be an increase in the demand for cylindrical structures such as URF (umbilical, riser, flowline) structures and spars, which are used operating in various seas. However, a cylindrical structure experiences vortex induced motion (VIM) in a current. In particular, for risers and umbilicals, it is important to identify the characteristics of the VIM because interference between structures can occur. In addition, various studies have been conducted to reduce VIM because it is the cause of fatigue damage to structures. The helical strake, which was developed for VIM reduction, has an excellent VIM reduction performance, but is difficult to install on structures and has a negative effect on heave motion. Therefore, the purpose of this study was to supplement the shortcomings of the helical strake and develop a high-performance reduction device. In the reduction device developed in this study, a string is placed around the structure inside the flow, causing vibration. The vibration of this string causes a small turbulence in the flow field, reducing the VIM effect on the structure. Finally, in this study, the 2-DOF motion characteristics of models without a suppression device, models with a helical strake, and models with a string were investigated, and their reduction performances were compared through model tests.

• Journal of Life Science
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• v.25 no.7
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• pp.801-809
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• 2015

Homotypic cell adhesion (homotypic aggregation) in activated monocytes plays a central role in physiological and pathological processes including inflammatory responses, differentiation and migration. The extract of the Prunus mume Sieb. et Zucc. fruit (Maesil) has potential benefits to human health; such as anti-viral, anti-microbial, and anti-cancer activities. Indeed, Maesil extract may modulate inflammatory responses via interference with homotypic aggregation in monocytes. In the present study, the molecular mechanisms underpinning the therapeutic efficacy of Maesil extract in inflammatory diseases were investigated. It was found that Maesil extract inhibited homotypic aggregation in lipopolysaccharide (LPS)-activated monocytes. This was mediated by reduction of nitric oxide (NO) production, partly via inhibition of inducible nitric oxide synthase (iNOS) expression in LPS-activated THP-1 cells. It was confirmed that NO inhibition is a key mechanism in Maesil induced blockade of monocyte aggregation through identification of reversal of this inhibitory effect by the NO-producing agent S-nitroso-N-acetyl penicillamine (SNAP). In addition, Maesil extract significantly attenuated LPS-induced IκB-α phosphorylation and NF-κB translocation into the nucleus. In conclusion, Maesil extract exerts anti-inflammatory effects via inhibition of homotypic aggregation of LPS-activated monocytes through mechanisms involving the suppression of NO production and NF-κB activity, suggesting Maesil extract as a potential therapeutic candidate for the prevention and treatment of chronic inflammatory diseases.