• Asian-Australasian Journal of Animal Sciences
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• 제28권11호
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• pp.1551-1557
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• 2015

The missing heritability has been a major problem in the analysis of best linear unbiased prediction (BLUP). We introduced the traditional genome-wide association study (GWAS) into the BLUP to improve the heritability estimation. We analyzed eight pork quality traits of the Berkshire breeds using GWAS and BLUP. GWAS detects the putative quantitative trait loci regions given traits. The single nucleotide polymorphisms (SNPs) were obtained using GWAS results with p value <0.01. BLUP analyzed with significant SNPs was much more accurate than that with total genotyped SNPs in terms of narrow-sense heritability. It implies that genomic estimated breeding values (GEBVs) of pork quality traits can be calculated by BLUP via GWAS. The GWAS model was the linear regression using PLINK and BLUP model was the G-BLUP and SNP-GBLUP. The SNP-GBLUP uses SNP-SNP relationship matrix. The BLUP analysis using preprocessing of GWAS can be one of the possible alternatives of solving the missing heritability problem and it can provide alternative BLUP method which can find more accurate GEBVs.

• 대한기계학회논문집A
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• 제29권3호
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• pp.395-402
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• 2005

Recently Multidisciplinary Design Optimization Based on Independent Subspaces (MDOIS), an MDO (multidisciplinary design optimization) algorithm, has been proposed. In this research, an MDO problem is defined for design of a belt integrated seat considering crashworthiness, and MDOIS is applied to solve the problem. The crash model consists of an airbag, a belt integrated seat (BIS), an energy absorbing steering system, and a safety belt. It is found that the current design problem has two disciplines - structural nonlin- ear analysis and occupant analysis. The interdisciplinary relationship between the disciplines is identified and is addressed in the system analysis step in MDOIS. Interdisciplinary variables are belt load and stiffness of the seat, which are determined in system analysis step. The belt load is passed to the structural analysis subspace and stiffness of the seat back frame to the occupant analysis subspace. Determined design vari- ables in each subspace are passed to the system analysis step. In this way, the design process iterates until the convergence criterion is satisfied. As a result of the design, the weight of the BIS and Head Injury Crite- rion (HIC) of an occupant are reduced with specified constraints satisfied at the same time. Since the system analysis cannot be formulated in an explicit form in the current example, an optimization problem is formu - lated to solve the system analysis. The results from MDOIS are discussed.

• 한국수학사학회지
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• 제24권3호
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• pp.109-143
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• 2011

1820년대 말에 런던대학칼리지의 초대 수학 교수가 되었던 드 모르간은 인접 분야인 자연철학 분야의 독특한 특징, 런던대학칼리지 학생들의 학업 수준 및 관심, 그리고 수학에 대한 부정적 인식들 속에서 자연스럽게 수학 '교육'의 문제에 특별한 관심을 기울이게 되었다. 그리고 학생들의 수준에 맞게 수학 분야들을 효과적으로 가르치려는 과정에서 다른 무엇보다도 수학의 기본 원리 및 개념들을 명확하게 이해시키고, 수학적 논의들을 엄밀하고 논리적인 방식으로 설명하는 데 집중하였다. 그가 연구자로만 남아 있을 수 없었던 상황에서, 그의 수학 교육은 UCL의 사회적 제도적 특징들, 수학 교육을 둘러싼 다양한 견해들, 그리고 인접 분야와의 관계 속에서 특정한 방식으로 구성되고 발전해 나가는 것이었다.

• 센서학회지
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• 제25권1호
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• pp.1-7
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• 2016

Bioelectrical impedance (BI) at popliteal regions was measured using a bioelectrical impedance measurement system (BIMS), which employs the multi-frequency and the two-electrode method. Experiments were performed as follows. First, a constant AC current of $800{\mu}A$ was applied to the popliteal regions (left and right) and the BI was measured at eight different frequencies from 10 to 500 kHz. When the applied frequency greater than 50 kHz was applied to human's popliteal regions, the BI was decreased significantly. Logarithmic plot of impedance vs. frequency indicated two different mechanisms in the impedance phenomena before and after 50 kHz. Second, the relationship between resistance and reactance was obtained with respect to the applied frequency using BI (resistance and reactance) acquired from the popliteal regions. The phase angle (PA) was found to be strongly dependent on frequency. At 50 kHz, the PA at the right popliteal region was $7.8^{\circ}$ slightly larger than $7.6^{\circ}$ at the left popliteal region. Third, BI values of extracellular fluid (ECF) and intracellular fluid (ICF) were calculated using BIMS. At 10 kHz, the BI values of ECF at the left and right popliteal regions were $1664.14{\Omega}$ and $1614.08{\Omega}$, respectively. The BI values of ECF and ICF decreased sharply in the frequency range of 10 to 50 kHz, and gradually decreased up to 500 kHz. Logarithmic plot of BI vs. frequency shows that the BI of ICF decreased noticeably at high frequency above 300 kHz because of a large decrease in the capacitance of the cell membrane.

• 스트레스연구
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• 제25권2호
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• pp.145-154
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• 2017

임부들의 심리적 안정과 태아와의 건강한 관계는 주산기 적응에 중요한 것으로 알려져 있다. 본 연구에서는 정신건강과 대인관계 개선에 효과적인 것으로 알려져 있는 자비명상을 임부용으로 개발하기 위하여 탐색적 예비연구를 진행하였다. 효과성과 개선점을 파악하기 위해 4주 자비명상 프로그램 참가자(n=8)들의 스트레스, 우울, 태아애착, 마음챙김 및 자기자비를 기저선과 사후에 측정하였으며, 포커스 그룹 인터뷰를 바탕으로 현상학적 분석을 실시하였다. 결과는 자비명상이 임부의 심리적 안정과 태아와의 관계에 긍정적인 영향을 줄 가능성이 나타났으며, 회기구성 및 가정수련 보강방안 등의 보완점들을 발견할 수 있었다. 본 연구가 임부용 자비명상 개발을 위한 이해의 폭을 넓히고, 추후 연구들을 촉진할 것이라 기대한다.

• International Journal of Knowledge Content Development & Technology
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• 제7권4호
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• pp.85-106
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• 2017

The purpose of this study is to measure and analyze the quality of service provided to the users by evaluating the service quality of the May 18 Democratic Uprising Archives, which is a representative,special subject repository, using the SERVQUAL model. To do this, revealing the relationship between factors such as service satisfaction of the archive users, overall service quality and intention of the action. Through this, this study developed service evaluation factors by considering the special subject repository.

• 대한가정학회지
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• 제40권3호
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• pp.21-40
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• 2002

The aim of this interdisciplinary study is to understand the relationship between the social behavior patterns and space elements, specially micro-housing sociological point of view. It analyzed korean typical floorplans in the apartment housing, focused on the 4-criteria contact or isolation between the individual persons, communication between the generations, hierarchy of the gender and socialization with neighbourhood. It determinate concrete space elements involved correspondent factors with users' social behavior. By reviewing those factors found, it is suggested also the planning concept, that response users' social orientation. As the practical alternatives, some prototypes have been developed not only for improvement of housing plans, but also for resonable housing supply and sustainable usage.

• 한국수학사학회지
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• 제23권1호
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• pp.67-78
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• 2010

이 글의 목적은 학문융합의 시대에 수학의 역할이 무엇인지를 밝히는 것이다. 수학은 학문융합에 있어서 세 가지 측면-이론적, 언어적, 정신적-에서 기여할 수 있다고 본다. 이를 위해 먼저 수학화의 과정을 살핀 후, 학문융합의 정도를 복합학문, 간학문, 초학문 등 세 단계로 구분한다. 그리고 학문융합에 기여하는 수학의 세 측면과 학문융합의 세 단계가 서로 대응관계에 있음을 주장한다.

• 한국자기공명학회논문지
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• 제24권2호
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• pp.47-52
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• 2020

Liquid-liquid phase separation (LLPS) of biomolecules, a newly-found phase behavior of molecules in the liquid phase, has shown to its relationship to various biological function and misfolding diseases. Extensive studies have increasingly revealed a general mechanism of LLPS and characterized the liquid droplet; ho wever, intermolecular interactions of proteins and structural states of LLPS-inducing proteins inside of the droplet remain largely unknown. Solution NMR spectroscopy has emerged as a powerful approach as it provides invaluable information on protein intermolecular interactions and structures at the atomic and residue level. We herein comprehensively address useful techniques of solution NMR including the effect of paramagnetic relaxation enhancement for the study on the LLPS and droplet based on recent studies.

• 아동학회지
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• 제28권5호
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• pp.55-72
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• 2007

Replication of the factor structure of the TBAQ(Toddler Behavior Assessment Questionnaire Goldsmith, 1988) in Korean 2-year-old children was examined by Multitrait Multimethod matrix of observed and reported child behavior. Participants included 113 toddlers and their mothers. Three factors comprising 63 items were identified and labeled as easy, difficult and fearful. On the Child Behavior Checklist(Achenbach & Edelbrock, 1983) difficult temperament was positively related to externalizing while fearful temperament was positively related to internalizing problems. Observation of inhibited child behavior in both unfamiliar social and nonsocial situations demonstrated a positive relationship to observed inhibition of fearful temperament. Easy temperament correlated negatively with both social inhibition and internal behavior problems. Results supported construct validity of TBAQ factors for Korean 2-year-old children.