• Proceedings of the KSRS Conference
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• v.2
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• pp.623-626
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• 2006

Group of genes controls the functioning of a cell by complex interactions. These interacting gene groups are called Gene Regulatory Networks (GRNs). Two previous data mining approaches, clustering and classification have been used to analyze gene expression data. While these mining tools are useful for determining membership of genes by homology, they don't identify the regulatory relationships among genes found in the same class of molecular actions. Furthermore, we need to understand the mechanism of how genes relate and how they regulate one another. In order to detect regulatory relationships among genes from time-series Microarray data, we propose a novel approach using frequent pattern mining and chain rule. In this approach, we propose a method for transforming gene expression data to make suitable for frequent pattern mining, and detect gene expression patterns applying FP-growth algorithm. And then, we construct gene regulatory network from frequent gene patterns using chain rule. Finally, we validated our proposed method by showing that our experimental results are consistent with published results.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.18 no.12
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• pp.1092-1100
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• 2005

We investigated a carbon nanotube (CNT) oscillator controlled by the thermal gas expansion using classical molecular dynamics simulations. When the temperature rapidly increased, the force on the CNT oscillator induced by the thermal gas expansion rapidly increased and pushed out the CNT oscillator. As the CNT oscillator extruded from the outer nanotube, the suction force on the CNT oscillator increased by the excess van der Waals(vdW) energy. When the CNT oscillator reached at the maximum extrusion point, the CNT oscillator was encapsulated into the outer nanotube by the suction force. Therefore, the CNT oscillator could be oscillated by both the gas expansion and the excess vdW interaction. As the temperature increased, the amplitude of the CNT oscillator increased. At the high temperatures, the CNT oscillator escaped from the outer nanotube, because the force on the CNT oscillator due to the thermal gas expansion was higher than the suction force due to the excess vdW energy. By the appropriate temperature controls, such as the maximum temperature, the heating rate, and the cooling rate, the CNT oscillator could be operated.

• Structural Engineering and Mechanics
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• v.9 no.3
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• pp.289-304
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• 2000

This study discusses on the experimental and analytical results of the global buckling tests, carried out on aluminum alloy double layer space grids composed of tubular members, ball joints and connecting bolts at the member ends, with the purpose of demonstrating the effectiveness of a simplified analysis method using an equivalent slenderness ratio for the members. Because very few experiments have been carried out on this type of aluminum space grids, the buckling behavior is investigated experimentally over the post buckling regions using several space grid specimen with various values for the member slenderness ratio. The observed behavior duping the experiments is compared with the analytically obtained results. The comparison is made based on two different schemes; one on the plastic hinge method considering a bending moment-axial force interaction for members and the other on a method using an equivalent slenderness ratio. It is confirmed that the equivalent slenderness method can be effectively applied, even in the post buckling regions, once the effects of the rotational rigidity at the ball joints are appropriately evaluated, because the rigidity controls the buckling behavior. The effectiveness of the equivalent slenderness method will be widely utilized for estimation of the ultimate strength, even in post buckling regions for large span aluminum space grids composed of an extreme large number of nodes and members.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3163-3168
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• 2013

Methylenetetrahydrofolate reductase (MTHFR) plays a central role in folate metabolism. This study with 381 esophageal cancer patients and 432 healthy controls was conducted to examine the association of MTHFR C677T and A1298C polymorphisms with susceptibility to esophageal cancer (EC) in a Chinese population. Compared with the CC genotype of MTHFR C677T, subjects carrying homozygote TT and variant genotypes (CT+TT) demonstrated reduced risk of EC with adjusted ORs (95% CI) of 0.44 (0.28-0.71) and 0.57 (0.37-0.88), respectively. However, no association was found between the MTHFR A1298C polymorphism and the risk of EC. Comparing to haplotype CA, haplotypes TA and TC could reduce the susceptibility to EC with adjusted ORs (95% CI) of 0.61(0.47-0.79) and 0.06 (0.01-0.43), respectively. In conclusion, the present study suggested that the MTHFR C677T polymorphism can markedly influence the risk of EC in Chinese.

• Proceedings of the KIPE Conference
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• 2003.11a
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• pp.271-274
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• 2003

In this paper, compare and analyze existent MPPT algorithms. Existent algorithms have defects which don't generate it in a partial shade or low insolation. Therefore, to supplement it, we design improved IncCond algorithm consisted of a Aux. switch and capacitor with Generation Control circuit which can always obtain maximum generation power at the factor which is reduced generational efficiency by partial shade. Generation Control circuit is method which can always get maximum output power as it regularly controls each voltage of serial connected solar cell. Accordingly, it can improve efficiency and confidence of utility interaction inverter. Construction of system use a low price PIC16F87X. We analyze special character according to system operation through simulation and prove the validity through experiments.

• Food Science of Animal Resources
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• v.32 no.3
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• pp.274-284
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• 2012

In this study, the effects of physical parameters (30-270 MPa of pressure, 3-57 min of time, and 1-$49^{\circ}C$ of temperature) on pork quality were investigated. Response surface methodology was used in order to monitor and model the changes in pork quality under varied pressure conditions. As quality characteristics, shear force, water holding capacity (WHC) and the CIE color of pork were measured, and optimum pressure conditions were evaluated by statistical modeling. Pressure improved the WHC of pork at relatively low temperature ($<25^{\circ}C$); however, the opposite occurred with increasing temperature. Although pressure and temperature affected the tenderness of the meat, interaction effects among variations were not observed. At pressure levels higher than 200 MPa, the color of pork differed markedly from that of the untreated controls. In particular, differential scanning calorimetry (DSC) revealed marked evidence of myosin denaturation. The present study demonstrates that pork quality varies depending on pressure conditions.

• Journal of Biomedical Engineering Research
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• v.13 no.3
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• pp.181-188
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• 1992

This paper provides an overview of system analysis of immunology. The theoretical research in this area is aimed at an understanding of the precise manner by which the immune system controls Infec pious diseases, cancer, and AIDS. This can provide a systematic plan for immunological experimentation by means of an integrated program of immune system analysis, mathematical modeling and computer simulation. Biochemical reactions and cellular fission are naturally modeled as nonlinear dynamical processes to synthesize the human immune system! as well as the complete organism it is intended to protect. A foundation for the control of tumors is presented, based upon the formulation of a realistic, knowledge based mathematical model of the interaction between tumor cells and the immune system. Ordinary bilinear differential equations which are coupled by such nonlinear term as saturation are derived from the basic physical phenomena of cellular and molecular conservation. The parametric control variables relevant to the latest experimental data are also considered. The model consists of 12 states, each composed of first-order, nonlinear differential equations based on cellular kinetics and each of which can be modeled bilinearly. Finally, tumor control as an application of immunotherapy is analyzed from the basis established.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.49 no.1
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• pp.33-40
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• 2000

In this paper, an integrated method for the path planning and motion control of wheeled mobile robots using a hybrid system model and control is presented. The hybrid model including the continuous dynamics and discrete dynamics with the continuous and discrete state vector is derived for a two wheel driven mobile robot. The architecture of the hybrid control system for real time path planning and following is designed which has the 3-layered hierarchical structure : the discrete event system using the digital automata as the higher process, the continuous state system for the wheel velocity controls as the lower process, and the interface system as the interaction process between the continuous system as the low level and the discrete event system as the high level. The reference motion commands for autonomous navigation are generated by the abstracted motion in the discrete event system. The motion control tasks including the feasible path planning and autonomous motion control with various initial conditions are investigated as the applications by the simulation studies.

• Journal of information and communication convergence engineering
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• v.2 no.2
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• pp.110-115
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• 2004

The prosthesis of current commercialized apparatus has considerable problems, requiring improvement. Especially, LLP(Lower Limb Prosthesis)-related problems have improved, but it cannot provide normal walking because, mainly, the gait control of the LLP does not fit with patient's gait manner. To solve this problem, HCI((Human Computer Interaction) that adapts and controls LLP postures according to patient's gait manner more effectively is studied in this research. The proposed control technique has 2 steps： 1) the multilayer neural network forecasts angles of gait of LLP by using the angle of normal side of lower limbs； and 2) the adaptive neural controller manages the postures of the LLP based on the predicted joint angles. According to the experiment data, the prediction error of hip angles was 0.32［deg.］, and the predicted error of knee angles was 0.12［deg.] for the estimated posture angles for the LLP. The performance data was obtained by applying the reference inputs of the LLP controller while walking. Accordingly, the control performance of the hip prosthesis improved by 80% due to the control postures of the LLP using the reference input when comparing with LQR controller.

• Safety and Health at Work
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• v.8 no.4
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• pp.393-397
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• 2017

Background: It has been suggested that engaging technology can empower individuals to be more proactive about their health and reduce their health risks. The aim of the present intervention was to study the effects of technology-aided testing and feedback on physical activity and biological age of employees in a middle-sized enterprise. Methods: In all, 121 employees (mean age $42{\pm}10$ years) participated in the 12-month three-arm cluster randomized trial. The fitness measurement process (Body Age) determined the participants' biological age in years. Physical activity was measured with the International Physical Activity Questionnaire Short Form. Results: Physical activity did not change during the intervention. Biological age (better fitness) improved in all groups statistically significantly (p < 0.001), but with no interaction effects. The mean changes (years) in the groups were -2.20 for the controls, e2.83 for the group receiving their biological age and feedback, and -2.31 for the group receiving their biological age, feedback, and a training computer. Conclusion: Technology-aided testing with feedback does not seem to change the amount of physical activity but may enhance physical fitness measured by biological age.