• 대한통합의학회지
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• 제10권3호
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• pp.141-150
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• 2022

Purpose : Community care occupational therapy is an integrated mediation method such as evaluating and mediating daily life activities, evaluating and modifying the environment, and providing information by visiting the home where the client resides. In this study, we examine the effect of implementing a community-care occupational therapy program on the levels of depression, quality of sleep, and quality of life of elderly individuals living alone. Methods : Among the users of organizations C and D located in City B, province A, South Korea, a total of 32 elderly citizens aged above 65 were chosen as the study subjects and randomly divided into an experimental group and a control group. For the experimental group, a total of 24 sessions, each lasting 60 minutes, comprising a community-care occupational therapy program and each organization's own program, were conducted, with each session conducted twice a week for a total of 12 weeks. On the other hand, those in the control group participated in the existing programs of their organizations. Changes in the levels of depression, quality of sleep, and quality of life before and after the intervention were compared using the GDSSF-K, GQOL, and GQOL. Results : Overall, the levels of depression, quality of sleep, and quality of life were found to improve among the experimental group after the intervention. In a between-group comparison of the changes before and after the intervention, the experimental group was found to exhibit a more statistically significant difference than that of the control group. Conclusion : The results obtained in this study confirm that community-care occupational therapy programs have a positive effect on the levels of depression, quality of sleep, and quality of life of elderly individuals living alone. This implies that such programs may represent an effective solution for the problems of these individuals.

• 대한통합의학회지
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• 제10권1호
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• pp.91-99
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• 2022

Purpose : The goal of this study is to examine the effect of robot assisted gait training (RAGT) on the kinematic factors (temporospatial gait parameters, gait cycle ratio, and gait line length) of gait in stroke patients. Methods : The subjects of this study were 24 stroke patients selected by inclusion criteria. Participants were randomly allocated to two groups: robot assisted gait training (n=11) and general neurological physical therapy group (n=11). In the robot-assisted gait training group, robot-assisted gait training was mediated for 30 minutes a day in addition to general neurological physical therapy. The general neurological physical therapy group was mediated by general neurological physical therapy for 30 minutes a day in addition to general neurological physical therapy. The number of interventions was 5 times a week for 5 weeks. In order to compare the kinematic factors of walking between the two groups, gait analysis was performed before and after 5 weeks of training using the Zebris gait analysis system. Results : As a result of the gait analysis of the two groups, there were significant differences in temporospatial gait variables (step length, stride length, step width, step time, stride time), gait cycle ratio (swing phase, stance phase) and gait line length. However, there was no significant difference in the cadence (temporospatial gait parameters) in the robot assisted gait training group compared to general neurological physical therapy group. Conclusion : It is considered to be a useful treatment for stroke patients to promote the recovery of gait function in stroke patients. Based on the results of this study, continuous robot assisted gait training treatment is considered to have a positive effect on gait ability, the goal of stroke rehabilitation. In the future, additional studies should be conducted on many subjects of stroke patients, the kinematic factors of the legs according to the severity of stroke and treatment period, and the effect of gait training.

• 대한통합의학회지
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• 제11권4호
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• pp.147-155
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• 2023

Purpose: Headache is a very common disease experienced at least once in daily life, and tension-type headaches have a high and increasing prevalence. Chronic headaches can cause functional damage and huge socioeconomic impacts. This study aimed to compare the effects of myofascial release technique with manual therapy and self-myofascial release technique using a foam roller on the pain threshold and body schema in patients with chronic tension-type headaches. Methods: The study was conducted on 20 patients living in Busan with chronic tension headaches. Myofascial release technique with manual therapy was performed on the suboccipital, sternocleidomastoid, scalene, and upper trapezius muscles. The self -myofascial release technique using a foam roller was applied to the cervical and thoracic muscles. A laterality test was performed using a recognized neck application developed to evaluate body schema ability. A pressure-pain threshold test was performed using an electronic pressure algometer to compare the results before and after the myofascial release technique. Results: After applying myofascial release with manual therapy and a foam roller, the pressure-pain threshold values showed significant changes in both groups (p<.05). As a result of the laterality test, myofascial release with manual therapy and a foam roller were applied to the painful area. The values showed significant changes in both groups (p<.05), but only the group using the foam roller showed a significant difference (p<.05) in painless areas. Conclusion: The myofascial release technique with manual therapy can be the primary treatment technique for pain control in painful areas. The self-muscle release technique using a foam roller can be an effective method when there is no pain or when maintenance is needed after pain control.

• Journal of Pharmaceutical Investigation
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• 제40권6호
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• pp.333-337
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• 2010

Combining cell- and gene-based therapy is a promising therapeutic strategy in regenerative medicine. The aim of this study was to develop genetically modified mesenchymal stem cell (MSC) aggregates using a poly(ethylene glycol) (PEG) hydrogel micro-well array technique. Stable PEG hydrogel micro-well arrays with diameters of 200 to $500\;{\mu}m$ were fabricated and used to generate genetically engineered MSC aggregates. Rat bone marrow-derived MSCs were transfected with a green fluorescent protein (GFP) plasmid as a reporter gene, and aggregated by culturing in the PEG hydrogel micro-well arrays. The resultant cell aggregates had a mean diameter of less than $200\;{\mu}m$, and maintained the mesenchymal phenotype even after genetic modification and cell aggregation. Transplantation of MSC aggregates that are genetically modified to express therapeutic or cell-survival genes may be a potential therapeutic approach for regenerative medicine.

• Journal of Acupuncture Research
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• 제41권
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• pp.168-175
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• 2024

The butterfly vertebra is a rare congenital anomaly of the spine, which arises from an asymmetric fusion defect in the embryonic vertebral column. This report delineates an integrative Korean medicine treatment administered to two patients who presented with low back pain associated with asymptomatic butterfly vertebrae. The patients received comprehensive treatment comprising acupuncture, Chuna therapy, pharmacopuncture, herbal medicine, and cupping therapy. The efficacy of the treatments was assessed utilizing diverse parameters, including a numerical rating scale, range of motion of the lumbar spine, Oswestry Disability Index, EuroQoL 5-Dimension 5-Level, and patient global impression of change. After the treatment, a notable improvement was noted in the evaluated indicators. These positive outcomes suggest that integrative Korean medicine treatment is suitable for patients experiencing low back pain associated with asymptomatic butterfly vertebrae.

• 대한통합의학회지
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• 제4권3호
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• pp.27-30
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• 2016

PURPOSE : The effect of the vestibular caloric stimulation with ice water on the autonomic nervous system was investigated using pulse oximetry. METHOD : Thirty-four healthy men and women were subject to a 2-minute vestibular caloric stimulation with ice water, and autonomic nervous activities (low frequency, high frequency, and total power) were measured before and after the vestibular caloric stimulation. Data were analyzed separately for men and women. RESULT : Low frequency, high frequency, and total power in the men and low frequency in the women were statistically significantly higher after vestibular caloric stimulation. High frequency and total power in the women were higher but not significantly different after vestibular caloric stimulation. CONCLUSION : Vestibular caloric stimulation with ice water increases autonomic nervous activities, with the variation being within the normal range. The test can be considered safe for use.

• 대한통합의학회지
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• 제3권1호
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• pp.63-69
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• 2015

Purpose: The purpose of this study was to investigate the differences in emotion recognition according to general characteristics of stroke patients. Method: The subjects consisted of 38 stroke patients receiving rehabilitation at S Hospital in Busan. Used the eMETT program to assess emotional cognition. Result: The age and duration of disease showed statistically significant differences in emotion recognition ability score, the gender and lesion showed a statistically significant difference in some emotion(p<.05). Conclusion: The results of this study it can be seen that the difference in emotion recognition ability in accordance with the general characteristics of the stroke. There will be a variety of future research related to standardized research or interventions targeted at stroke patients and normal controls to be carried out.

• Korean Chemical Engineering Research
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• 제61권4호
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• pp.570-575
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• 2023

Targeted anticancer drug delivery systems are needed to enhance therapeutic efficacy by selectively delivering drugs to tumor cells while minimizing off-target effects, improving treatment outcomes and reducing toxicity. In this study, a silica-based nanocarrier capable of targeting drug delivery to cancer cells was developed. First, silica nanoparticles were synthesized by the Stöber method using the surfactant cetyltrimethylammonium bromide (CTAB). Increasing the ratio of EtOH in the solvent produced uniformly spherical silica nanoparticles. Washing the nanoparticles removed unreacted residues, resulting in a non-toxic carrier for drug delivery in cells. Upon surface modification, the pH-responsive polymer, polyethyleneimine (PEI) exhibited slow doxorubicin release at pH 7.4 and accelerated release at pH 5.5. By exploiting this feature, we developed a system capable of targeted drug release in the acidic tumor microenvironment.

• 대한통합의학회지
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• 제2권4호
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• pp.41-48
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• 2014

Purpose : The purpose of this survey was to investigate the effect on job satisfaction and organizational commitment according to the job types of Pusan area physical therapists figuring out structural causality between job satisfaction and organizational commitment. Method : This survey was conducted through structured questionnaire for the physical therapists working in Pusan area, and data from 217 therapists were utilized in the final analysis. Data collection was deployment questionnaire using Google Docs (online survey), The SPSS 21.0 program was used according to for research purposes independent t-test was used for individual and job characteristics, was used according to job types and job satisfaction and organizational commitment are logistic regression analysis, correlation analysis and chi-square test. Result : The results of this study were as follows. 1. Overall job satisfaction according to the job types was appeared musculoskeletal physical therapist more 4 times. 2. Job types according to the organizational commitment did not make direct effect. Conclusion : Number of musculoskeletal physical therapist than neurological physical therapist was fewer and there were many per day treatment of patients, but overall job satisfaction was appeared that is higher. This is thought that job types affects more than working environment.

• 대한통합의학회지
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• 제1권1호
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• pp.69-76
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• 2013

Purpose : The purpose of this study is to look into relationship between job stress and self esteem, job satisfation in rehabilition professional physical therapist. Method : The subjects of this study were consist of 200 physical therapists of Busan rehabilition hospital. Data were collected from September 1 to October 4 in 2012 by structurated questionnaires. Results : Physical therapist Job satisfaction and gender classification according to self esteem were statistically significant differences respectively(T=2.02, P=.044), (T=2.17, P=.031). Job satisfaction and age according to the therapist according to the number of job stress were statistically significant differences respectively(F=3.57, P=.030), (F=3.18, P=.044). Job satisfaction, job stress and self-esteem of a physical therapist were statistically significant correlation (P<.01) Conclusion : Effective countermeasure for ways to relieve stress, and the necessity of developing the program at the same time, for the relief of the physical therapist, the physical therapist yourself to have self-esteem.