• 제목/요약/키워드: Integrated factors

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Development of Culturally Contextualized Counseling Strategies to Enhance Resilience in Families of Dementia Patients (치매 환자 가족의 회복탄력성 강화를 위한 문화 맥락적 상담 전략 개발)

  • Kyoung-Haing Lee
    • The Journal of the Convergence on Culture Technology
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    • 제10권5호
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    • pp.243-252
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    • 2024
  • This study aimed to propose counseling strategies to enhance the resilience of families caring for dementia patients, a rapidly growing population. Through a literature review, we analyzed the characteristics and influencing factors of resilience in families of dementia patients and examined existing counseling approaches. The results revealed that the resilience of these families is formed through complex interactions of individual, familial, and socio-environmental factors, and has dynamic characteristics that change according to the progression of dementia. Based on these findings, we proposed differentiated counseling strategies for each family member and strategies considering the Korean cultural context. The proposed integrated counseling model includes a multidimensional approach that considers cultural context, family member characteristics, and stages of dementia progression. This study highlights the need for an integrated approach considering cultural context to enhance the resilience of families caring for dementia patients and suggests the necessity for future research to verify the effectiveness of actual counseling interventions.

Caffeine inhibits adipogenesis through modulation of mitotic clonal expansion and the AKT/GSK3 pathway in 3T3-L1 adipocytes

  • Kim, Hyo Jung;Yoon, Bo Kyung;Park, Hyounkyoung;Seok, Jo Woon;Choi, Hyeonjin;Yu, Jung Hwan;Choi, Yoonjeong;Song, Su Jin;Kim, Ara;Kim, Jae-woo
    • BMB Reports
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    • 제49권2호
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    • pp.111-115
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    • 2016
  • Caffeine has been proposed to have several beneficial effects on obesity and its related metabolic diseases; however, how caffeine affects adipocyte differentiation has not been elucidated. In this study, we demonstrated that caffeine suppressed 3T3-L1 adipocyte differentiation and inhibited the expression of CCAAT/enhancer binding protein (C/EBP)α and peroxisome proliferator-activated receptor (PPAR)γ, two main adipogenic transcription factors. Anti-adipogenic markers, such as preadipocyte secreted factor (Pref)-1 and Krüppel-like factor 2, remained to be expressed in the presence of caffeine. Furthermore, 3T3-L1 cells failed to undergo typical mitotic clonal expansion in the presence of caffeine. Investigation of hormonal signaling revealed that caffeine inhibited the activation of AKT and glycogen synthase kinase (GSK) 3 in a dose-dependent manner, but not extracellular signal-regulated kinase (ERK). Our data show that caffeine is an anti-adipogenic bioactive compound involved in the modulation of mitotic clonal expansion during adipocyte differentiation through the AKT/GSK3 pathway.

A Study on Integrated Approaching Factors of Environmentally-Friendly Companies Certification Scheme and Environmental Impact Assessment of Korea (환경친화기업지정제도와 환경영향평가제도에서의 통합적 환경관리 요소에 대한 기초적 연구)

  • Hong, Jun-Suk;Kim, Kyu-Yeon;Kwon, Oh-Sang
    • Journal of Environmental Impact Assessment
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    • 제17권2호
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    • pp.113-124
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    • 2008
  • A worldwide trend of permitting system for industrial installation to achieve a high level of protection of the environment has been moved from single media to multimedia in approach. The Council of the European Community issued the Directive 96/61/EC, the IPPC Directive, concerning integrated pollution prevention and control in 1996. The IPPC Directive is one of the most ambitious legal measures that the European Union (EU) has initiated with a view to applying the prevention principle for industrial activities. The IPPC aims to achieve the integrated prevention and reduction of environmental pollution emitted by those industrial installations with a higher potential of emissions to the environment. Organization for Economic Cooperation and Development (OECD) recommended on Environmental Performance Reviews of Korea in 2006 that IPPC permitting concept should be considered for large stationary sources at the national and regional levels. Any Korean law doesn't provide for integrated pollution control with a single process covering all pollution from economic activities. However, one exception might be the "environmentally-friendly companies" certification scheme, introduced in 1995, in which participants agree to meet targets beyond the legal emission limit values in exchange for government technical and financial support to operate environmental management systems. The other exception might be Environmental impact assessment (EIA) of projects, in 1977, which has been strengthened and reinforced to be more preventive through development of the prior environmental review system (PERS) in 1999. The aim of this work is to introduce the contents of IPPC Directive at the viewpoint of Korea policy and to survey the integrated approaching concept of Environmentally-Friendly Companies (EFC) Certification Scheme and EIA policy of Korea. The study will be helpful in the future to prepare the infrastructure of integrated permitting system and to enforce the integrated permit which the authorities of local government issues on industrial activities. It can be said that the data calculated through both EFC Certification Scheme and EIA will be discussed as worthful information to determine Korean BAT reference notes for integrated permitting process.

Exploring a Learning Progression for Integrated Process Skills in Earth Science Inquiry (지구과학 탐구에서 통합 탐구 기능에 대한 학습발달과정 탐색)

  • Lee, Kiyoung;Park, Jaeyong
    • Journal of the Korean earth science society
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    • 제38권3호
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    • pp.222-238
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    • 2017
  • The purpose of this study is to explore a learning progression for integrated process skills in Earth science inquiry. For the purpose, a hypothetical learning progression (HLP) that capture how students' integrated process skills of science become sophisticated over time is developed through the literature review. This learning progression contains four components of the integrated process skills of science: designing inquiry, collecting data, analyzing data, and forming conclusion. Three hypothetico-deductive inquiry tasks of Earth science that start from recognition of the given problem to the forming conclusion are developed in order to document students' integrated process skills. A total of 126 students from middle, high, college level students participated in this study. After conducting the Earth science inquiry tasks, the integrated process skills of individual students are assessed by element based on HLP. In addition, the validation process for HLP was administered by applying the Rasch model using the students' assessment data. Finally, based on the analyzed data, the empirical learning progression (ELP) is developed by revising and supplementing the HLP. This study can help to find scaffolding methods to effectively improve the students' integrated process skills in Earth science inquiry class by identifying the factors that affect students' development of integrated process skills. It also provide implications for improving teachers' PCK of Earth science inquiry instruction.

Risk Factors of Postoperative Nosocomial Pneumonia in Stage I-IIIa Lung Cancer Patients

  • Wang, Zeng;Cai, Xin-Jun;Shi, Liang;Li, Fei-Yan;Lin, Neng-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권7호
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    • pp.3071-3074
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    • 2014
  • Background: To investigate the related risk factors of postoperative nosocomial pneumonia (POP) in patients withI-IIIa lung cancer. Methods: Medical records of 511 patients who underwent resection for lung cancer between January 2012 to December 2012 were retrospectively reviewed. Risk factors of postoperative pneumonia were identified and evaluated by univariate and multivariate analyses. Results: The incidence of postoperative pneumonia in these lung cancer patients was 2.9% (15 cases). Compared with 496 patients who had no pneumonia infection after operation, older age (>60), histopathological type of squamous cell carcinoma and longer surgery time (>3h) were significant risk factors by univariate analysis. Other potential risk factors such as alcohol consumption, history of smoking, hypersensitivity, hypertension, diabetes mellitus and so on were not showed such significance in this study. Further, the multivariate analysis revealed that old age (>60 years) (OR 5.813, p=0.018) and histopathological type of squamous cell carcinoma (OR 5.831, p<0.001) were also statistically significant independent risk factors for postoperative pneumonia. Conclusions: This study demonstrated that being old aged (>60 years) and having squamous cell carcinoma histopathological type might be important factors in determining the risk of postoperative pneumonia in lung cancer patients after surgery.

An Approach to Multi-Stage Decision Process for Optimum Location (단계적 최적립지 결정 방법에 관한 연구)

  • 김복만;김지일
    • Journal of Korean Society of Industrial and Systems Engineering
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    • 제17권30호
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    • pp.11-24
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    • 1994
  • The problem of location for industries and residential quarters has undoubtedly been one of the most important factors to enhance human activities and standard of living. Nonetheless. there seem to be no such theories or approaches as to cope with this problem satisfactorily. As a matter of fact the evaluation of proposed locations so far has stuck to quantitative factors and thus the results are often rejected by the public or individuals. In deciding the location of industrial complex and/or residential quarters, the qualitative factors often play more important role than the quantitative factors. Moreover, it is quite possible for a proposed location to be disapproved for reasons other than quantifiable factors. This work presents an approach to multi-stage decision process of optimum location, particularly for residential quarters. The proposed approach consists of four stages. At the first stage, candidates for the location are searched and checked against musts. After this screening process, the candidates fulfilling the musts are evaluated both quantitatively and qualitatively at the second stage. The third stage is devoted to the integrated evaluation using diffrent weights for the two factors. At the final stage, a location is selected among the candidates evaluated at the earlier stages. This approach has been applied to and tested on a apartment-building project in Ulsan area. Difficulties arising from quantifying factors were encountered as expected. Sometimes decisions could be a matter of taste of the individuals concerned.

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Road Safety Assessment by Using Integrated Evaluation Methods of Road Design Consistency (도로선형 설계일관성 통합평가방법론을 활용한 안전성 평가)

  • Ko, Chun-Soo;Lee, Jong-Hak;Ku, Ji-Sun;Noh, Kwan-Sub
    • International Journal of Highway Engineering
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    • 제15권1호
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    • pp.121-126
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    • 2013
  • PURPOSES: Road Design Consistency Evaluation can guarantee road alignments with safety factors, however it can be hard work to deal with general car accident factors in only this evaluation index. Ideal Road Design Consistency Evaluation is show the mutual balance of road alignment and human factors with a variety of factors for road safety. METHODS: This study carried out overall road safety evaluations which are methods of running speeding consistency and car platoon safety analysis (driver's behaviors factors) as well. RESULTS: Out of 13 sections in a experimental road layout, safety factors of 8 sections showed 'Good' or 'Fair' status. However, 'Poor' results were found out in 5 sections. Particularly, it showed the different outcomes among the 4 evaluation methods used in this study. CONCLUSIONS: Road safety countermeasures were proposed for the potentially dangerous sections in road which failed to identify in the other methods. This study will contribute toward future study of more reliable Road Design Consistency Evaluation in the future for road safety.

Priority Analysis of the Determining Factors of Faculty Startups in Medical Schools (의과대학 교원 창업 결정요인 우선순위 분석)

  • Sung Jin Chung;Dae Geun Kim
    • Korea Journal of Hospital Management
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    • 제29권3호
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    • pp.11-25
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    • 2024
  • Purpose: This study investigates the factors influencing medical school faculty's entrepreneurial decisions and prioritizes these factors. Methodology: The study examines the determinants of entrepreneurial decisions among medical school faculty by reviewing prior studies. These determinants were categorized into four perspectives: resource-based, industrial organization, entrepreneur characteristics, and other. Using the Analytic Hierarchy Process(AHP), the study analyzed the relative priorities of 27 specific indicators. Surveys were conducted with medical school faculty with startup experience, professors with relevant expertise, and organizational leaders involved in entrepreneurship. A total of 33 responses were validated for consistency, and an empirical analysis identified the priority of factors influencing medical school faculty startups. Findings: The findings reveal that 'entrepreneur characteristics' and 'institutional and organizational support' are the highest priority factors for medical school faculty. Key resource-based factors include the 'leave of absence' or 'concurrent employment policy,' availability of 'professional human resources,' and 'organizational support' specializing in startups. An integrated analysis shows that while intellectual resources such as research publications, patents, and physical space are necessary, the highest priority is given to leave policies, professional human resources, and organizational support. Practical Implication: Medical school faculty are recognized as key innovation agents in the bio-health industry. The results provide crucial insights for policymakers and stakeholders at governmental, institutional, and organizational levels. Strengthening self-competence, increasing entrepreneurship opportunities, and establishing professional human resources and organizational support within medical universities or hospitals are critical for facilitating medical school faculty startups.

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Study on the Selecting of Suitable Sites for Integrated Riparian Eco-belts Connecting Dam Floodplains and Riparian Zone - Case Study of Daecheong Reservoir in Geum-river Basin - (댐 홍수터와 수변구역을 연계한 통합형 수변생태벨트 적지 선정방안 연구 - 금강 수계 대청호 사례 연구 -)

  • Bahn, Gwonsoo;Cho, Myeonghyeon;Kang, Jeonkyeong;Kim, Leehyung
    • Journal of Wetlands Research
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    • 제23권4호
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    • pp.327-341
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    • 2021
  • The riparian eco-belt is an efficient technique that can reduce non-point pollution sources in the basin and improve ecological connectivity and health. In Korea, a legal system for the construction and management of riparian eco-belts is in operation. However, it is currently excluded that rivers and floodplains in dam reservoir that are advantageous for buffer functions such as control of non-point pollutants and ecological habitats. Accordingly, this study presented and analyzed a plan to select a site for an integrated riparian ecol-belt that comprehensively evaluates the water quality and ecosystem characteristics of each dam floodplain and riparian zone for the Daecheong Dam basin in Geum River watershed. First, the Daecheong Dam basin was divided into 138 sub-basin with GIS, and the riparian zone adjacent to the dam floodplain was analyzed. Sixteen evaluation factors related to the ecosystem and water quality impact that affect the selection of integrated riparian eco-belt were decided, and weights for the importance of each factor were set through AHP analysis. The priority of site suitability was derived by conducting an integrated evaluation by applying weights to sub-basin by floodplains and riparian zone factors. In order to determine whether the sites derived through GIS site analysis are sutiable for actual implementation, five sites were inspected according to three factors: land use, pollution sources, and ecological connectivity. As a result, it was confirmed that all sites were appropriate to apply integrated riparian ecol-belt. It is judged that the riparian eco-belt site analysis technique proposed through this study can be applied as a useful tool when establishing an integrated riparian zone management policy in the future. However, it might be necessary to experiment various evaluation factors and weights for each item according to the characteristics and issues of each dam. Additional research need to be conducted on elaborated conservation and restoration strategies considering the Green-Blue Network aspect, evaluation of ecosystem services, and interconnection between related laws and policy and its improvements.

Need of Health Center-based Integrated Healthcare Services for the Elderly in Rural Area (농촌지역 보건소 중심의 노인 통합보건의료서비스 필요도)

  • Won, Eun-Sook;Chang, Sei-Jin;Park, Jong-Ku;Hyun, Sook-Jung;Kim, Chun-Bae
    • Journal of agricultural medicine and community health
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    • 제32권1호
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    • pp.27-39
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    • 2007
  • Objectives: The challenge of an increasing elderly population has coupled with everpresent social concerns in Korea. A major problem in health center for the frail older people is that medical, healthcare, and welfare services are often fragmented in terms of providers and settings without appropriate coordination. The purpose of this study was to investigate the need of health center-based integrated healthcare services and its related factors for the elderly. Methods: A total of 110 elderly people who had visited at a county Health Center were interviewed using a self-administered questionnaire from November to December, 2005. The questionnaire consists of five domains according to the Program of All-inclusive Care for the Elderly. Results: Respondents had high need (total mean score with the 5-point Likert-type sacle: 3.67) of health center-based integrated healthcare services including home visiting service (mean: 4.08), chronic disease care service (mean: 4.06), and transportation service (mean 4.05). According to the results of hierarchical multiple regression analysis, among three regression models the magnititude of the variance of full model that is explained by the need of welfare-domain service was significantly larger than two reduced model. Income was a significant variable in increasing the need of health care and welfare services. Conclusions: This study suggests that the health center-based integrated healthcare services for the elderly must be continuously developed and provided for the health promotion and improved the quality of life of the elderly who live in rural area in Korea.