• 제목/요약/키워드: Inner ear

검색결과 106건 처리시간 0.021초

Fabrication and Vibration Characterization of a Partially Etched-type Artificial Basilar Membrane

  • Kang, Hanmi;Jung, Youngdo;Kwak, Jun-Hyuk;Song, Kyungjun;Kong, Seong Ho;Hur, Shin
    • 센서학회지
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    • 제24권6호
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    • pp.373-378
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    • 2015
  • The structure of the human ear is divided into the outer ear, the middle ear, and the inner ear. The inner ear includes the cochlea that plays a very important role in hearing. Recently, the development of an artificial cochlear device for the hearing impaired with cochlear damage has been actively researched. Research has been carried out on the biomimetic piezoelectric thin film ABM (Artificial Basilar Membrane) in particular. In an effort to improve the frequency separation performance of the existing piezoelectric thin film ABM, this paper presents the design, fabrication, and characterization of the production and performance of a partially etched-type ABM material. $O_2$ plasma etching equipment was used to partially etch a piezoelectric thin film ABM to make it more flexible. The mechanical-behavior characterization of the manufactured partially etched-type ABM showed that the overall separation frequency range shifted to a lower frequency range more suitable for audible frequency bandwidths and it displayed an improved frequency separation performance. In addition, the maximum magnitude of the vibration displacement at the first local resonant frequency was enhanced by three times from 38 nm to 112 nm. It is expected that the newly designed, partially etched-type ABM will improve the issue of cross-talk between nearby electrodes and that the manufactured partially etched-type ABM will be utilized for next-generation ABM research.

대전한방병원 한방안이비인후피부과로 내원한 귀 질환 환자 특성 분석 -2012년 3월부터 2019년 2월까지- (A Clinical Analysis on Outpatients with Ear Diseases of Korean Medicine Ophthalmology, Otolaryngology & Dermatology Department at Daejeon Korean Medicine Hospital - From March, 2013 to February, 2019-)

  • 제하경;안재현;김수영;정현아
    • 한방안이비인후피부과학회지
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    • 제33권2호
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    • pp.23-42
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    • 2020
  • Objectives : This study is designed to analyze the outpatients who received medical treatments for ear diseases in ophthalmology & otolaryngology & dermatology clinic of Daejeon Korean Medical Hospital from March, 2013 to February, 2019. Methods : We classified the otology outpatients who received medical treatments in ophthalmology & otolaryngology & dermatology clinic of Daejeon Korean Medical Hospital from March, 2012 to February, 2019 according to gender, year, age, season, anatomical parts, and main diagnosis. The statistical analysis was performed using SPSS 25.0. Results : 1. The number of outpatients with ear diseases were 880; 505 female and 375 male. The number of female patients were approximately 1.7 times higher. 2. The average age of the outpatients with ear diseases were 50.0. The number of middle-aged (40-50s) patients were 439, which is almost half the number(49.9%) of the whole patients. 3. By analyzing the number of patients classified by year, we found out that the number of the outpatients with ear diseases has increased gradually for the past 7 years. 4. In the analysis of the number of patients classified by the anatomical parts of the ear, the inner ear diseases group were the largest, amounting to 79.3% of the whole patients. 5. In the analysis of the number of patients classified by main diagnosis, Tinnitus turns out to be the largest group with 338 patients, followed by sudden sensorineural hearing loss, dizziness, otalgia, Meniere's syndrome, otitis, auditory tube dysfunction, BPPV. 6. No statistical-significant difference were shown in the analysis of the number of patients classified by season. Conclusions : It turns out that patients with ear diseases had increased by the years, and middle aged patients (40-50s) were the largest among the age groups. Most of the patients came for the inner-ear diseases, and tinnitus, sudden sensorineural hearing loss took up the largest proportions.

Histopathologic Characterization of Metastatic Ceruminous Gland Adenocarcinoma in a Dog

  • Kang, Dong-Hyeon;Park, Dae-Sik;Lee, Eun-Sung;Kim, Jae-Hoon
    • 한국임상수의학회지
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    • 제36권5호
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    • pp.266-270
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    • 2019
  • A 13-year-old spayed female American cocker spaniel dog was submitted to an animal hospital with a mass from left ear canal and enlarged left parotid lymph node. Given one-year history of odorous exudates and chronic otitis externa, total ear canal ablation was performed. Grossly, because of the neoplastic mass in both inner and outside of annular cartilage in external ear, vertical ear canal was severely narrowed. Histologically, there were numerous proliferated glands in the ear canal mass. Many neoplastic glands contained secretory vesicles on the free margin and necrotic cellular debris. Severe multifocal necrosis and strong invasion were also observed throughout the mass. Massive metastatic foci of glandular structures originated from ceruminous gland were presented in the enlarged parotid lymph node. Neoplastic glandular epithelia contained PAS-positive diastase-resistant eosinophilic cytoplasmic granules. Immunohistochemically, the neoplastic cells showed positive reactions for cytokeratin (CK) 7 and negative for CK 5/6. Based on the clinical implication and gross findings, histopathology and immunohistochemistry, this case was diagnosed as metastatic ceruminous gland adenocarcinoma in the American cocker spaniel.

청각 보철을 위한 자극패턴 추출에 관한 연구 (A Study on the Extraction of the Excitation Pattern for Auditory Prothesis)

  • 박상희;윤태성;이재혁;백승화
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1987년도 전기.전자공학 학술대회 논문집(II)
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    • pp.1322-1325
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    • 1987
  • In this study, the excitation pattern, which can be sensated by a man having hearing loss due to the damage of inner ear, is extracted, and the procedure of the auditory speech signal processing is simulated with the computer. Therefore, the excitation pattern is extracted by the neural tuning model satisfying the physiological characteristic of the inner ear and by the infor.ation extracted from speech signal. The firing pattern is also extracted by inputting this excitation pattern to the auditory neural model. With this extracted firing pattern, the possibility that the patient can sensate the speech signal is studied by the computer simulation.

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Application of Photobiomodulation in Hearing Research: Animal Study

  • Lee, Jae-Hun;Jung, Jae Yun
    • Medical Lasers
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    • 제9권1호
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    • pp.1-5
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    • 2020
  • Hearing organs have unique characteristics and have a role in processing external sensory signals. Sensory hair cells and nerve fibers in the organ of Corti can be damaged by various causes and they do not regenerate themselves. Medication used for clinical treatment for the inner ear is limited due to the anatomical structure of the inner ear. Photobiomodulation (PBM) is a therapeutic approach that uses various sources of light and the success of PBM therapy is highly reliant on the parameters of the light sources. The positive effects of PBM have been reported in various clinical fields. This paper summarizes the previously reported research on PBM for the treatment of hearing damage in animal models.

인공와우 이식자의 역행성 청신경 복합활동전위 (Antidromic Electrically Compound Action Potential in Cochlear Implantees)

  • 허승덕;정성욱;정승현
    • 말소리와 음성과학
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    • 제1권4호
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    • pp.203-207
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    • 2009
  • Electrically evoked compound action potentials (ECAP) have originated from the distal end of the auditory nerve. ECAP are characterized as the difference between the clearly large trough (N) and the following positive peak (P). N-wave occurs around $200-400\;{\mu}s$ after stimulus onset and P-wave at around $400-800\;{\mu}s$. Contrary to expectations, positive peaked ECAP (pp-ECAP) was dominated by a relatively large-amplitude positive following negative peak. pp-ECAP can be recorded from the sites on or near the surgically exposed nerve trunk in animal models and/or in cases of monophasic stimulation. This study will provide the causes of the appearance of pp-ECAP in cases of cochlear implant recipients using imaging studies and medical records and statistically analysis between N-P and P-N on the amplitude input-output function (amp-I/O) for the prediction of the possibilities of clinical tools. Thirteen children participated in the study and received a Cochlear CI-24RE (CA). ECAP was recorded using auto-NRT (Cochlear Ltd., Australia) at four to five weeks post surgery. pp-ECAP was measured from 36 electrodes and typical ECAP from 220 electrodes. There was no abnormality in the imaging study and operation finding in patients with typical ECAP. pp-ECAP was found at the inner ear anormaly and ossification in imaging study and gel-state inner ear fluid was observed in the operation finding. The amplitude of pp-ECAP increased depending on current intensities, but amp-I/O increase more gradually than in the case of typical ECAP (p=0.003). pp-ECAP is antidromic potential which can record from the inner ear anormaly and ossified cochlear. Amp-I/O also depends on current intensity as well typical ECAP. These results provide a useful tool for audiological evaluation for the spiral ganglion cell status to the value of pp-ECAP.

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CMOS공정을 이용한 Inner Hair Cell의 모델링에 적합한 면적 효율적인 저역 통과필터의 설계 (An Area Efficient Low Pass Filter for Inner Hair Cell using CMOS Process)

  • 류승탁;이광;최배근;조규형
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2001년도 하계학술대회 논문집 D
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    • pp.2567-2569
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    • 2001
  • 본 논문에서는 내이(Inner ear)의 한 부분을 차지하는 Inner Hair Cell을 구현함에 있어 필수적인 요소인 낮은 극점을 갖는 저역통과필터(LPF)를 최소의 면적으로 구현하기 위한 설계방법을 언급한다. 이를 위해 본 논문에서는 CMOS Compatible Lateral BJT (CLBT)를 사용하여 능동소자의 등가 저항을 증가시켜 커패시터의 값을 획기적으로 줄일 수 있는 기법의 LPF와 gm-C필터를 이용한 LPF를 전류모드로 설계하였다. 저전력 특성과 큰 임피던스 특성을 얻기 위해 모든 트랜지스터는 약반전 영역에서 동작하고 극점은 1kHz근처에 존재한다.

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중이강내 Terramycin산포로 초래된 심한 감각신경성난청 (Profound Sensorineural Deafness Following the Application of Terramycin Powder Intratympanically)

  • 박옥희;김기주;이태정;조중환
    • 대한기관식도과학회:학술대회논문집
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    • 대한기관식도과학회 1981년도 제15차 학술대회연제순서 및 초록
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    • pp.37.2-38
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    • 1981
  • 근래 천공된 고막에 Ear drop를 사용하는 것은 그 효과가 의간시되 오고, 또 그 안전성도 도전을 받아왔다. 전신적으로 투여하였을때는 이독성이 없는 많은 약제들도, 중이강에 국소적으로 투여했을 때는 이독성이 될수있다. Stupp등(1973)에 의하면, Neomycin, polymyxin-G, gentamycin, erythromycin, tetracycline penicillin중, 다만 penicillin만이 독작용이 없다고 알려져 있다. Ototoxic antibiotics는 round window막을 투과하여 내이, perilymph에 들어가고 또다시 Reissner's막을 통하여 Endolymph에 이르게 된다고 보고있다. 주병변은 Stria vascularis의 degeneration, Sensory epithelia의 degeneration 및 Ganglion cell의 degeneration을 이르킨다. 63세 여자의 양측천공성 만성 중이염 환자가 가정에서 중이강내에 Terramycin분말 한 Capsule을 양이에 나누어 넣고, 심한 Sensorineural Deafness를 초래, 6개월이 지난 현재, 병변의 호전을 보지못하고 있는 일증례를 문헌적고찰과 함께 보고하는 바이다.

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담훈으로 변증된 말초성 현훈 환자 5례에 대한 임상보고 - 반하백출천마방 가감방을 중심으로 - (Five Case Report of Peripheral Vertigo Diagnosed Dam Hun with Oriental Medical Treatment - Banhabaeckchulchunma-tang gagam -)

  • 안소현;최정식;조충식;김철중
    • 동의생리병리학회지
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    • 제23권1호
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    • pp.263-268
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    • 2009
  • Pripheral vertigo occurs if there is a problem with the part of the inner ear that controls balance or with the vestibular nerve, which connects the inner ear to the brainstem. Peripheral vertigo is caused by benign paroxysmal positional vertigo(BPPV), Menieres disease, vestibular neuronitis, or labyrinthitis. We diagnosed five patients who have severe vertigo as peripheral vertigo and Dam Hun. We treated them with Banhabaeckchulchunma-tang gagam and acupuncture. After treatment, vertigo and other symptoms -nausea, vomiting, abdominal discomfort had improved. So I report these cases, but more clinical case reports are needed.