• Archives of Plastic Surgery
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• v.39 no.3
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• pp.249-252
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• 2012

Nicolau syndrome is a rare complication of intramuscular injection consisting of ischemic necrosis of skin, soft tissue, and muscular tissue that arises locoregionally. The characteristic pattern is pain around the injection site, developing into erythema, a livedoid dermatitis patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. Three patients were injected with drugs (diclofenac sodium, ketoprofen, meperidine) for pain relief. Three patients complained of pain, and a skin lesion was observed, after which necrosis developed on their buttocks. Each patient underwent debridement and coverage. The wound healed uneventfully. We report three cases of Nicolau syndrome in the buttocks following diclofenac intramuscular injection.

• Design & Manufacturing
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• v.13 no.2
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• pp.12-16
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• 2019

For optimal injection molding, various molding conditions should be combined well. Therefore, engineers should be thoroughly familiar with mold design, fabrication, and injection molding. The choice of resin among the various molding conditions is closely related to the productivity of the molded part and the deformation after molding, so the engineer must select the appropriate resin. Engineers work on the basis of data provided by resin manufacturers during molding. However, in actual molding work, it is necessary to apply values slightly different from those provided to obtain molded articles of desired performance. In this study, various deformations of molded products were compared with respect to crystalline resin and amorphous resin when molded according to the data provided by the resin maker and molded at the changed values at the work site.

• Korean journal of applied entomology
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• v.15 no.3 s.28
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• pp.107-110
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• 1976

A Witches'-broom disease of jujube (Zizyphus jujuba) with which mycoplasma-like bodies are associated is wide spread in South Korea. Jujube trees with witches'-broom symptoms were selected from 15-20 year old planting and treated with solution of oxytetracycline hydrochloride (Terramycin). Treatments were 1) one injection on April; 2) one postharvest injection on October; 3) two injections (April and July); 4) three injections (April, June and August) and 5) an untreated control. Each injection consisted of 500ml of 1,000 p.p.m. solution of oxytetracycline HCl transfused into affected trees from plastic reservoir through plastic tubes connected to 3 small holes drilled in the basal part of the tree trunks. Complete remission of witches'-broom symptoms was accomplished within one growing season by one spring (April) injection. One postharvest (Oct.) injection also prevented the symptoms in the following growing season. Two and three injection treatments prevented the symptoms for at least two growing seasons and restored previously severely diseased trees to normal or near normal conditions. Remission of symptoms was found only above the injection site while current season witches'-brooms developed from areas below the injection site and from untreated main scaffolds. The results of this experiment demonstrates that transfusion treatment with oxytetracyclin HCl is feasible for the practical control of witches'-broom of jujube.

• The Journal of Engineering Geology
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• v.25 no.2
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• pp.179-188
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• 2015

Although permeating injection is ideal for grouting reservoir embankments, it is usually combined with fracturing injection for grouting, which can disturb the original soil. Compaction with low expansive pressure followed by grout injection can overcome this problem. An expansive compaction (EC) packer was developed in this work to easily apply sequential injection and compaction at a work site. Furthermore, to achieve compaction around the grouting hole, a mixture of expansive admixtures and grout was injected with the EC packer to trigger an increase in volume of the grout material. This work verifies the compaction effect of the EC packer and the expansive admixture. It reports the concepts of the EC packer, the range of expansive compaction, the effectiveness of injection, and the results of indoor tests performed to verify the effectiveness of the expansive admixtures. The indoor testing comprised a preparatory test and the main test. The preparatory test assessed the admixtures for their compaction effects, while the main test measured and analyzed the admixtures' expansive force, pressure, and compaction effect with a mold to verify the effectiveness of the compaction effect.

• International Journal of Computer Science & Network Security
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• v.23 no.2
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• pp.199-202
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• 2023

Carriage return (CR) and line feed (LF), also known as CRLF injection is a type of vulnerability that allows a hacker to enter special characters into a web application, altering its operation or confusing the administrator. Log poisoning and HTTP response splitting are two prominent harmful uses of this technique. Additionally, CRLF injection can be used by an attacker to exploit other vulnerabilities, such as cross-site scripting (XSS). Email injection, also known as email header injection, is another way that can be used to modify the behavior of emails. The Open Web Application Security Project (OWASP) is an organization that studies vulnerabilities and ranks them based on their level of risk. According to OWASP, CRLF vulnerabilities are among the top 10 vulnerabilities and are a type of injection attack. Automated testing can help to quickly identify CRLF vulnerabilities, and is particularly useful for companies to test their applications before releasing them. However, CRLF vulnerabilities can also lead to the discovery of other high-risk vulnerabilities, and it fosters a better approach to mitigate CRLF vulnerabilities in the early stage and help secure applications against known vulnerabilities. Although there has been a significant amount of research on other types of injection attacks, such as Structure Query Language Injection (SQL Injection). There has been less research on CRLF vulnerabilities and how to detect them with automated testing. There is room for further research to be done on this subject matter in order to develop creative solutions to problems. It will also help to reduce false positive alerts by checking the header response of each request. Security automation is an important issue for companies trying to protect themselves against security threats. Automated alerts from security systems can provide a quicker and more accurate understanding of potential vulnerabilities and can help to reduce false positive alerts. Despite the extensive research on various types of vulnerabilities in web applications, CRLF vulnerabilities have only recently been included in the research. Utilizing automated testing as a recurring task can assist companies in receiving consistent updates about their systems and enhance their security.

• Journal of radiological science and technology
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• v.42 no.3
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• pp.209-215
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• 2019

Comparison of the effective dose of the chest and the equivalent dose of the lens site in the radiation workers working at four medical institutions with the PET / CT room located in one metropolitan city and province from April 1 to June 30, 2018 Respectively. Radioactive medicine were measured at the time of dispensing and at the time of injection. In this experiment, the average dispensing time per patient was 5.7 minutes and the average injection time was 3.1 minutes. The equivalent dose at the lens site was $0.78{\mu}Sv/h$ for 1 mCi, and the effective dose for chest was $0.18{\mu}Sv/h$ per 1 mCi. The equivalent dose at the lens site during injection was $0.88{\mu}Sv/h$ per mCi and the effective dose of chest was $0.20{\mu}Sv/h$ per mCi. The daily effective dose of the chest was $0.9{\pm}0.6{\mu}Sv$ and the equivalent dose of the lens site was $3.6{\pm}1.4{\mu}Sv$ during daily dosing for 20 days. The effective dose of the chest during the day was $0.6{\pm}0.5{\mu}Sv$ and the equivalent dose of the lens was $2.2{\pm}1.0{\mu}Sv$. At the time of dispensing, the equivalent dose of the lens was $0.187{\pm}0.035mSv$, the effective dose of the chest was $0.137{\pm}0.055mSv$, the equivalent dose of the lens was $0.247{\pm}0.057mSv$, and the effective dose of the monthly chest was $0.187{\pm}0.021mSv$. As a result of the corresponding sample test, the equivalent dose and the effective dose of the chest, the effective dose of the chest, the effective dose of the chest, the effective dose of the chest, The equivalent dose of the lens and the effective dose of the chest were statistically significant (p<0.05) with a significance of 0.000. However, there was no statistically significant difference (p>0.05) between the equivalent dose and the effective dose of the chest, the equivalent dose of the lens at the time of injection, and the effective dose of the chest at 0.138 and 0.230, respectively.

• Journal of Pharmacopuncture
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• v.18 no.1
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• pp.56-62
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• 2015

Objectives: The purpose of the study is to assess both the approximate lethal dose and the single dose intramuscular injection toxicity of Danggui (Angelica gigantis radix) pharmacopuncture (DGP) in Sprague-Dawley (SD) rats. Methods: The experiments were conducted at the good laboratory practice (GLP) laboratory, Biotoxtech Co., which is a laboratory approved by the ministry of food and drug safety (MFDS). The study was performed according to the GLP regulation and the toxicity test guidelines of the MFDS (2009) after approval of the institutional animal care and use committee of Biotoxtech. Single doses of DGP were injected intramuscularly into the rats in three test groups of 6 week old SD rats (5 male and 5 female rats per groups) in the amounts of 0.1, 0.5, and 1.0 mL/animal for groups 2, 3, and 4, respectively, and normal saline solution in the amount of 1.0 mL/animal was injected intramuscularly into the rats (5 male and 5 female rats) in the control group. Observations of the general symptoms and weight measurements were performed during the 14 day observation period after the injection. Hematologic and serum biochemical examination, necropsy, and a local tolerance test at the injection site were done after the observation period. Results: No death was observed in three test groups (0.1, 0.5 and 1.0 mL/animal group). In addition, the injection of DGP had no effect on general symptoms, weights, hematologic and serum biochemical examination, and necropsy. The results from the local tolerance tests at injection site showed no treatment related effects in the SD rats. Conclusion: The results of single dose intramuscular injection of DGP suggest that the approximate lethal dose is above 1.0 mL/animal for both male and female SD rats and that intramuscular injection of DGP may be safe.

• The Journal of Engineering Geology
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• v.30 no.4
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• pp.603-615
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• 2020

The design factors of artificial recharge are determined by considering the hydrogeological characteristics of the aquifer. The optimal design factors for artificial recharge were derived after performing the injection tests step by step for each injection type (vertical well, ditch and mixed type), which were built in the test site of the study area. It was analyzed that the difference in the injection effect according to the diameter of the injection well was not large, and the 100 mm well was evaluated as appropriate in consideration of the availability and economy of land use. Since the injection effect was well maintained even in the upper rock, the depth of the injection well was proposed for the alluvial layer and the upper rock layer. On the other hand, in four cases of filter media in the ditch, it was analyzed that the penetration efficiency and the hydraulic interference effect indicated excellent injection performance when a filter medium of 10 to 30 mm diameter was filled in the ditch. In addition, the proper spacing of the injection wells was analyzed as 9~12 m considering the interference efficiency. The interference efficiency attenuation coefficient per 1 m of hole spacing was calculated to be 1.75% in this area. In the future study, the artificial recharge design factors obtained in this stage are applied and verified on site construction and operation. Also it is expected to contribute to securing water in areas where there is always a lack of water.

• Tunnel and Underground Space
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• v.26 no.1
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• pp.12-23
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• 2016

For a successful accomplishment of Carbon Capture Sequestration (CCS) projects, appropriate injection conditions should be designed and optimized for site specific geological conditions. In this study, we evaluated the effect of injection conditions such as injection temperature and injection rate on the geomechanical stability of CCS system in terms of TOUGH-FLAC simulator, which is one of the well-known T-H-M coupled analysis methods. The stability of the storage system was assessed by a shear slip potential of the pre-existing fractures both in a reservoir and caprock, expressed by mobilized friction angle and Mohr stress circle. We demonstrated that no tensile fracturing was induced even in the cold CO2 injection, where the injected CO2 temperature is much lower than that of the reservoir and tensile thermal stress is generated, but shear slip of the fractures in the reservoir may occur. We also conducted a scenario analysis by varying injected CO2 volume per unit time, and found out that it was when the injection rate was decreasing in a step-wise that showed the least potential of a shear slip.

• Journal of Pharmacopuncture
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• v.18 no.3
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• pp.42-48
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• 2015

Objectives: The aim of the study is to investigate both the single-dose intramuscular injection toxicity and the approximate lethal dose of water-soluble Carthami-flos and Cervi cornu parvum pharmacopuncture (WCFC) in male and female Sprague-Dawley (SD) rats. Methods: The study was conducted at Biotoxtech Co. according to the Good Laboratory Practice (GLP) regulation and the toxicity test guidelines of the Ministry of Food and Drug Safety (MFDS) after approval of the Institutional Animal Care and Use Committee. Dosages for the control, high dose, middle dose and low dose groups were 0.5 mL/animal of saline and 0.5, 0.25 and 0.125 mL/animal of WCFC, respectively. WCFC was injected into the muscle of the left femoral region by using a disposable syringe (1 mL, 26 gauge). The general symptoms and mortality were observed 30 minutes, 1, 2, 4, and 6 hours after the first injection and then daily for 14 days after the injection. The body weights of the SD rats were measured on the day of the injection (before injection) and on the third, seventh, and fourteenth days after the injection. Serum biochemical and hematologic tests, necropsy examinations, and histopathologic examinations at the injection site were performed after the observation period. Results: No deaths, abnormal clinical symptoms, or significant weight changes were observed in either male or female SD rats in the control or the test (0.125, 0.25, and 0.5 mL/animal) groups during the observation period. No significant differences in hematology and serum biochemistry and no macroscopic abnormalities at necropsy were found. No abnormal reactions at injection sites were noted on the topical tolerance tests. Conclusion: The results of this single-dose toxicity study show that WCFC is safe, its lethal doses in male and female SD rats being estimated to be higher than 0.5 mL/animal.