• Title/Summary/Keyword: Initial growth region

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Long-term pharyngeal airway changes after bionator treatment in adolescents with skeletal Class II malocclusions

  • Han, Seimin;Choi, Yoon Jeong;Chung, Chooryung J.;Kim, Ji Young;Kim, Kyung-Ho
    • The korean journal of orthodontics
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    • v.44 no.1
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    • pp.13-19
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    • 2014
  • Objective: The aim of this study was to evaluate long-term changes in the pharyngeal airway dimensions after functional appliance treatment in adolescents with skeletal Class II malocclusions. Methods: Pharyngeal airway dimensions were compared between subjects with skeletal Class II malocclusions (n = 24; mean age: $11.6{\pm}1.29$ years) treated with a Class II bionator and age-matched control subjects with skeletal Class I occlusions (n = 24; mean age: $11.0{\pm}1.21$ years) using a series of lateral cephalograms obtained at the initial visit (T0), after treatment (T1), and at the completion of growth (T2). Results: The length of the nasopharyngeal region was similar between adolescents with skeletal Class I and Class II malocclusions at all time points, while the lengths of the upper and lower oropharyngeal regions and the pharyngeal airway areas were significantly smaller in the skeletal Class II adolescents before treatment when compared to the control adolescents (p < 0.05). However, following treatment with a functional appliance, the skeletal Class II adolescents had increased pharyngeal airway dimensions, which became similar to those of the control subjects. Conclusions: Functional appliance therapy can increase the pharyngeal airway dimensions in growing adolescents with skeletal Class II malocclusions, and this effect is maintained until the completion of growth.

Composition-control of Mn-Zn Ferrite Single Crystal Using a Phase Diagram (상평형도를 이용한 Mn-Zn 페라이트 단결정 조성 조절)

  • Je, Hae-June;Kim, In-Tae;Hong, Kug-Sun
    • Analytical Science and Technology
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    • v.5 no.3
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    • pp.327-332
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    • 1992
  • Mn-Zn ferrite single crystals show some fluctuations in composition along the direction of growth by the conventional Bridgman method. The single crystal with a uniform composition was obtained by maintaining the liquid composition content. For example, two batches of powder were prepared : one is consisted of 52 mol% of $Fe_2O_3$, 30 mol% of MnO, and 18 mol% Zn(Composition A), and the other 53 mol% of $Fe_2O_3$, 28.5 mol% of MnO, and 18.5 mol% ZnO(Composition B). Crack-free single crystals with the uniform composition B were grown in a size of 60mm diameter, 300mm long by melting the pellets of composition A and followed by supplying the composition B as tablets. Initial permeabilities were obtained above 600 at 5 MHz in the region of 30~270 mm along the direction of growth.

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Effects of Pediococcus pentosaceus strains isolated from three different types of Kimchi in ICR mice infected with Escherichia coli or Salmonella Typhimurium

  • Han Jin Oh;Jun Pyo Lee;Ji Hwan Lee;Yong Ju Kim;Jae Woo An;Se Yeon Chang;Young Bin Go;Dong Cheol Song;Hyun Ah Cho;Min Gyu Jeon;Yo Han Yoon;Jin Ho Cho
    • Korean Journal of Agricultural Science
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    • v.49 no.1
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    • pp.1-10
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    • 2022
  • One hundred and twenty imprinting control region (ICR) mouse with initial body weights of 26 ± 2 g (5 weeks old) were assigned to six treatments for a two-week feeding trial to determine the effect of Pediococcus pentosaceus strains (PpS) which were isolated from three different types of Kimchi in ICR mice infected with Escherichia coli (Ec) or Salmonella Typhimurium (ST). Six groups constituted a normal control group without Ec or ST orally administrated (NC-; n = 20), a normal control group (NC+; n = 20), a group for which Lactobacillus plantarum was orally administrated (LP; n = 20), a group for which PpS A was orally administrated (PSA; n = 20), a group for which PpS B was orally administrated (PSB; n = 20), and a group for which PpS C was orally administrated (PSC; n = 20), the latter five groups constituted the Ec infected groups and the ST infected groups of 10 mice each. LP and PSC showed significantly (p < 0.05) improved growth performance compared to the other groups, except for NC- in the Ec infected mice group. NC+ showed significantly lower (p < 0.05) growth performance compared to the other groups, except for NC- in the ST infected mice groups. Regarding the Ec and Salmonella counts in the intestine, the LP and PSC groups had significantly lower (p < 0.05) counts than the NC+ and PSB groups. In conclusion, LP and PSC strains isolated from Kimchi can act as probiotics by inhibiting Ec and ST.

Liquid Phase Epitaxial Growth of GaAs on InP Substrates (액상에피택시 방법에 의한 InP기판상의 GaAs 이종접합 박막 성장)

  • Kim, Dong-Geun;Lee, Hyeong-Jong;Im, Gi-Yeong;Jang, Seong-Ju;Jang, Seong-Ju;Kim, Jong-Bin;Lee, Byeong-Taek
    • Korean Journal of Materials Research
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    • v.4 no.5
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    • pp.600-607
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    • 1994
  • Optimum exper~mental conditions were established for the growth of heteroepitaxial GaAs layers on InP using liquid phase epitaxy (LPE) technique. Results showed that the optimum growth temperature was $720^{\circ}C$ at a cooling rate of $0.5^{\circ}C$/min. Surface morphology of the grown layers significantly improved by addition of about 0.005wt% Se to the Ga growth melt, which effectively suppressed melt-back of InP substrates into the melt during the initial stage of growth. It was observed that the quality of GaAs layers also improved substantially when the substrates patterned with grating structure were used, as determined by the (400) double crystal X-ray diffraction. The transmission electron microscopy observation indicated t.hat the misfit dislocations interact with each other at the grating region, resulting in a lower dislocation density in the upper GaAs layer.

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Trap characteristics of charge trap type NVSM with reoxidized nitrided oxide gate dielectrics (재산화 질화산화 게이트 유전막을 갖는 전하트랩형 비휘발성 기억소자의 트랩특성)

  • 홍순혁;서광열
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.12 no.6
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    • pp.304-310
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    • 2002
  • Novel charge trap type memory devices with reoxidized oxynitride gate dielectrics made by NO annealing and reoxidation process of initial oxide on substrate have been fabricated using 0.35 $\mu \textrm{m}$ retrograde twin well CMOS process. The feasibility for application as NVSM memory device and characteristics of traps have been investigated. For the fabrication of gate dielectric, initial oxide layer was grown by wet oxidation at $800^{\circ}C$ and it was reoxidized by wet oxidation at $800^{\circ}C$ after NO annealing to form the nitride layer for charge trap region for 30 minutes at $850^{\circ}C$. The programming conditions are possible in 11 V, 500 $\mu \textrm{s}$ for program and -13 V, 1ms for erase operation. The maximum memory window is 2.28 V. The retention is over 20 years in program state and about 28 hours in erase state, and the endurance is over $3 \times 10^3$P/E cycles. The lateral distributions of interface trap density and memory trap density have been determined by the single junction charge pumping technique. The maximum interface trap density and memory trap density are $4.5 \times 10^{10} \textrm{cm}^2$ and $3.7\times 10^{18}/\textrm{cm}^3$ respectively. After $10^3$ P/E cycles, interlace trap density increases to $2.3\times 10^{12} \textrm{cm}^2$ but memory charges decreases.

Quantitative Assessment of the Quality of Regional Adaptation Trial Data for Crop Model Improvement (작물 모형 개선을 위한 지역적응시험 자료의 정량적 품질 평가)

  • Hyun, Shinwoo;Seo, Bo Hun;Lee, Sukin;Kim, Kwang Soo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.22 no.3
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    • pp.194-204
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    • 2020
  • Cultivar parameters, which are key inputs to a crop growth model, have been estimated using observation data in good quality. Observation data with high quality often require considerable labor and cost, which makes it challenging to gather a large quantity of data for calibration of cultivar parameters. Alternatively, data in sufficient quantity can be collected from the reports on the evaluation of cultivars by region although these data are of questionable quality. The objective of our study was to assess the quality of crop and management data available from the reports on the regional adaptation trials for rice cultivars. We also aimed to propose the measures for improvement of the data quality, which would aid reliable estimation of cultivar parameters. DatasetRanker, which is the tool designed for quantitative assessment of the data for parameter calibration, was used to evaluate the quality of the data available from the regional adaptation trials. It was found that these data for rice cultivars were classified into the Silver class, which could be used for validation or calibration of key cultivar parameters. However, those regional adaptation trial data would fall short of the quality for model improvement. Additional information on management, e.g., harvest and irrigation management, can increase the quantitative quality by 10% with the minimum effort and cost. The quality of the data can also be improved through measurements of initial conditions for crop growth simulations such as soil moisture and nutrients. In addition, crop model improvement can be facilitated using crop growth data in time series, which merits further studies on development of approaches for non-destructive methods to monitor the crop growth.

Metalorganic Chemical Vapor Deposition of Copper Films on TiN Substrates Using Direct Liquid Injection of (hfac)Cu(vtmos) Precursor ((hfac)Cu(vtmos)의 액체분사법에 의한 TiN 기판상 구리박막의 유기금속 화학증착 특성)

  • Jun, Chi-Hoon;Kim, Youn-Tae;Kim, Dai-Ryong
    • Korean Journal of Materials Research
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    • v.9 no.12
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    • pp.1196-1204
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    • 1999
  • We have carried out copper MOCVD(metalorganic chemical vapor deposition) onto the reactive sputtered PVD-TiN and rapid thermal converted RTP-TiN substrates using direct liquid injection for effective delivery of the (hfac)Cu(vtmos) [$C_{10}H_{13}O_{5}CuF_{6}$Si: 1,1,1,5,5,5-hexafluoro-2,4- pentadionato (vinyltrimethoxysilane) copper (I)] precursor. Especially, the influences of deposition conditions and the substrate type on growth rate, crystal structure, microstructure, and electrical resistivity of copper deposits have been discussed. It is found that the film growth with 0.2ccm precursor flow rate become mass-transfer controlled up to Ar flow rate of 200sccm and pick-up rate controlled at a vaporizer above 1.0Torr reactor pressure. The surface-reaction controlled region from 155 to 225$^{\circ}C$ at 0.6Torr reactor pressure results in the apparent activation energies of 12.7~14.1kcal/mol, and above 224$^{\circ}C$ the growth rate with $H_2$ addition could be improved compared to the pure Ar carrier. The Cu/RTP-TiN structures which have high copper nucleation density in initial stage of growth show more pronounced (111) preferred orientations and lower electrical resistivities than those on PVD-TiN. The variation of electrical resistivity with substrate temperature reflects the three types of film microstructure changes, showing the lowest value for the deposit at 165$^{\circ}C$ with small grains of good contacts.

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Additive Effects on Magnetic Properties in High Permeability Mn Zn Ferrite (고투자율 Mn-Zn 페라이트의 첨가물 효과에 따른 자기적 특성연)

  • Jeong, Gap-Gyo;Choe, Seung-Cheol
    • Korean Journal of Materials Research
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    • v.3 no.5
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    • pp.497-504
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    • 1993
  • Effects of $Ta_2O_5,ZrO_2$ and $SiO_2$ addition on magnetic properties of 0.02wt%$Bi_2O_3$ and 0 . 0 5 wt%$CaCO_3$ doped Mn-Zn ferrites(58.5mol% $Fe_2O_3$, 25.5 mol% ZnO) were investigated. E:lectrlcal resistivity and magnetic properties such as the initial permeability($\mu_i$), loss factor(tan$\delta$), coercive force Hc(m0c) were measured. With lncreasing $Ta_2O_5$ and $ZrO_2$ addition, the following effects were observed: I ) Decreasing of the average grain size; 2) lncreasing of the electrical resistivity and initial permeability; 3) Ilecreasmg of loss factor values. (very low loss esprcially at high frequency region) ; 4 ) Fine and uniform microsrructures were obtamed at O.lwt% nddecl samples. In case of $SiO_2$ addition, anomalous grain growth and degradation of magnetic properties were observed. The obtained maximum initial permeability value was 6260 at IOkHz. $25^{\circ}C$ from 0.02wt%$Bi_2O_3$. 0.05wt%$CaCO_3$, 0.lwt%$Ta_2O_5$ added sample, the corresponded relative loss factor (tan$\delta /\mu_i$)for the sample was $4.2 \times 10^{-6}$.

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Effect of Delayed Transplanting plus Water Stress on the Growth and Yield of the Rice Plants (한발로 인한 벼의 이앙지연 및 수분결핍장애가 생육 및 수량에 미치는 영향)

  • 권용운;소창호;권순국
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.28 no.3
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    • pp.79-88
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    • 1986
  • Drought occurs most frequently and severely around transplanting season of the rice plants in Korea. Shortage of water due to drought for the paddy fields often delays transplanting, and less often the rice plants are subjected to water stress after delayed transplanting. The present study aimed at quantification of the rice crop loss due to delayed transplanting, different inten3ity of water stress, and the combined effect of delay in transplanting followed by water stress for better use of limited water for irrigation under drought. The rice variety Chucheong, a japonica, and Nampung, an indica x japonica, were grown, transplanted to 1/200 a plastic pots, and subjected to different timing of transplanting and degree of water stress under a rainfall autosersing, sliding clear plastic roof facility with completely randomized arrangement of 5 replications. The results obtained are summarized as follows: 1.Twelve days or 22 days delay in transplanting without water stress reduced rice yield by 25% and 43% in the japonica variety, and by 15% and 60% in the indica x japonica variety. 2.The 10 days or 20 days water stress developed without irrigation after drainage in the rice plants transplanted at proper time lowered the water potential at the paddy soil 10cm deep to -4 bar, and -12 bar and caused rice yield reduction by 14%, and 45% in the japonica variety and by 8%, and 50% in the indica X japonica variety. 3.The 12 days delay in transplanting and 10 days or 20 days water stress reduced rice yield by 39% and 59% in the japonica variety, and by 38% and 52% in the indica x japonica variety. The 22 days delay in transplanting plus 10 days water stress caused yield reduction by 76%, i.e. meaningless yield, in both varieties. 4.The intermittent irrigation just to wet the soil body for 10 days after 10 days water stress without irrigation increased rece yield by 12 to 16% compared to the rice plants water stessed without irrigation continuously for 20 days in both varieties respectively. 5.The above results suggest strongly 1) to transplant the rice plants at proper .time even with some water stress rather than delay for sufficient water from later rainfall, and 2) to distribute insufficient irrigation water to broader area of transplanted rice with limited irrigation for better use of limited irrigation water. A greater sensitivity of japonica variety to a moderate water stress than the indica X japonica variety during initial rooting and tillering stage was noticed. To cope with frequent drought in rice culture, firstly the lasting time of transplanting without yield reduction should be clarified by region and variety, and secondly a scheme of rational distribution of limited water should be developed by region with better knowledge on the varietal distribution of limited water should be developed by region with better knowledge on the varietal responses to varying intensity of water stress.

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Transcription factor EGR-1 transactivates the MMP1 gene promoter in response to TNFα in HaCaT keratinocytes

  • Yeo, Hyunjin;Lee, Jeong Yeon;Kim, JuHwan;Ahn, Sung Shin;Jeong, Jeong You;Choi, Ji Hye;Lee, Young Han;Shin, Soon Young
    • BMB Reports
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    • v.53 no.6
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    • pp.323-328
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    • 2020
  • Matrix metalloproteinase 1 (MMP-1), a calcium-dependent zinccontaining collagenase, is involved in the initial degradation of native fibrillar collagen. Tissue necrosis factor-alpha (TNFα) is a pro-inflammatory cytokine that is rapidly produced by dermal fibroblasts, monocytes/macrophages, and keratinocytes and regulates inflammation and damaged-tissue remodeling. MMP-1 is induced by TNFα and plays a critical role in tissue remodeling and skin aging processes. However, the regulation of the MMP1 gene by TNFα is not fully understood. We aimed to find additional cis-acting elements involved in the regulation of TNFα-induced MMP1 gene transcription in addition to the nuclear factor-kappa B (NF-κB) and activator protein 1 (AP1) sites. Assessments of the 5'-regulatory region of the MMP1 gene, using a series of deletion constructs, revealed the requirement of the early growth response protein 1 (EGR-1)-binding sequence (EBS) in the proximal region for proper transcription by TNFα. Ectopic expression of EGR-1, a zinc-finger transcription factor that binds to G-C rich sequences, stimulated MMP1 promoter activity. The silencing of EGR-1 by RNA interference reduced TNFα-induced MMP-1 expression. EGR-1 directly binds to the proximal region and transactivates the MMP1 gene promoter. Mutation of the EBS within the MMP1 promoter abolished EGR-1-mediated MMP-1 promoter activation. These data suggest that EGR-1 is required for TNFα-induced MMP1 transcriptional activation. In addition, we found that all three MAPKs, ERK1/2, JNK, and p38 kinase, mediate TNFα-induced MMP-1 expression via EGR-1 upregulation. These results suggest that EGR-1 may represent a good target for the development of pharmaceutical agents to reduce inflammation-induced MMP-1 expression.