• Journal of the Institute of Electronics Engineers of Korea CI
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• v.49 no.4
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• pp.54-61
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• 2012

This paper proposes a fusion method of the queen-bee evolution into the rank-based control of mutation probability for improving the performances of genetic algorithms. The rank-based control of mutation probability which showed some performance improvements than the original method was a method that prevented individuals of genetic algorithms from falling into local optimum areas and also made it possible for the individuals to get out of the local optimum areas if they fell into there. This method, however, showed not good performances at the optimization problems that had a global optimum located in a small area regardless of the number of local optimum areas. We think that this is because the method is insufficient in the convergence into the global optimum, so propose a fusion method of the queen-bee evolution into this method in this paper. The queen-bee evolution inspired by reproduction process of queen-bee is a method that can strengthen the convergency of genetic algorithms. From the extensive experiments with four function optimization problems in order to measure the performances of proposed method we could find that the performances of proposed method was considerably good at the optimization problems whose global optimum is located in a small area as we expected. Our method, however, showed not good performances at the problems whose global optima were distributed in broad ranges and even showed bad performances at the problems whose global optima were located far away. These results indicate that our method can be effectively used at the problems whose global optimum is located in a small area.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.45 no.2
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• pp.65-73
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• 2008

The characterization process for the accurate color reproduction in mobile phone with camera and LCD is popular. The camera and LCD characterization, gamut mapping process is necessary to map the camera's input color stimulus, CIEXYZ value, into the LCD's output color stimulus. Each characterization is the process estimating the relation between input and output signals. In case of LCD, because of output device, the output color stimulus for the arbitrary input signal can be measured by spectro-radiometer However, in the camera, as the input device, the characterization is an inaccurate and needs the manual works in the process obtaining the output signal because the input signal can not be generated. Moreover, after gamut mapping process, the noise is increased because the optimized gamma tone curve of camera for the noise is distorted by the characterization. Thus, this paper proposed the system of obtaining the output signal of camera and the method of gamma correction for the noise. The camera's output signal is obtained by RGB values of patches from captured the color chart image. However, besides the illumination, the error for the location of the chart in the viewfinder is generated when many camera modules are captured the chart. The method of correcting the position to correct the error from manual works. The position of camera is estimated by captured image. This process and moving of camera is accomplished repeatedly, and the optimized position can be obtained. Moreover, the lightness curve of camera output is corrected partly to reduce the noise from the characterization process.

• The KIPS Transactions:PartD
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• v.13D no.6 s.109
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• pp.823-832
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• 2006

The Purpose of Similarity(Reproduction) Degree Appraisal is to determine the equality or similarity between two programs and it is a system that presents the technical grounds of judgment which is necessary to support the resolution of software intellectual property rights through expert eyes. The most important things in proceeding software appraisal are not to make too much of expert's own subjective judgment and to acquire the accurate-appraisal results. However, up to now standard research and development for its systematic techniques are not properly made out and as different expert as each one could approach in a thousand different ways, even the techniques for software appraisal types have not exactly been presented yet. Moreover, in the analyzing results of all the appraisal cases finished before, through a practical way, we blow that there are some damages on objectivity and accuracy in some parts of the appraisal results owing to the problems of existing appraisal procedures and techniques or lack of expert's professional knowledge. In this paper we present the model for the standardization of software-similarity-appraisal techniques and objective-evaluation methods for decreasing a tolerance that could make different results according to each expert in the same-evaluation points. Especially, it analyzes and evaluates the techniques from various points of view concerning the standard appraisal process, setting a range of appraisal, setting appraisal domains and items in detail, based on unit processes, setting the weight of each object to be appraised, and the degree of logical and physical similarity, based on effective solutions to practical problems of existing appraisal techniques and their objective and quantitative standardization. Consequently, we believe that the model for the standardization of software-similarity-appraisal techniques will minimizes the possibility of mistakes due to an expert's subjective judgment as well as it will offer a tool for improving objectivity and reliability of the appraisal results.

• Development and Reproduction
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• v.15 no.1
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• pp.71-76
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• 2011

Due to its role in maintaining the health of scientific societies, research ethics (or integrity) is notably receiving attention by academia, governments and even individuals who are not engaged in scientific researches. In this paper, I will introduce some valuable papers dealt with plagiarism as a representative research misconduct. In general, researcher's results that will soon be published must meet the crucial scientific criteria: originality, accuracy, reproducibility, precision and research ethics. The definition of plagiarism is "appropriation of another person's ideas, processes, results, or words without giving appropriate credit." Compared to fabrication and falcification, plagiarism is often considered as a minor misconduct. With intentionality, however, plagiarism can be corresponding to 'theft of intellectual product'. The context of plagiarism is not restricted to the stage of publication. It can be extended to prior stages of proposing (i.e. preparing the research proposal) and performing (executing the research), and reviewing (writing the review papers). Duplicate publication is regarded as a self-plagiarism in broad interpretation of plagiarism. To avoid dangers of plagiarism, earnest efforts from all members of scientific community are needed. First of all, researchers should keep 'transparency' and 'integrity' in their scientific works. Editorial board members and reviewers should keep fairness and well-deserved qualification. Government and research foundations must be willing to provide sufficient financial and policy support to the scientific societies; Up-graded editorial services, making good use of plagiarism detection tools, and thorough instruction on how to write a honest scientific paper will contribute to building up a healthy basis for scientific communities.

• Development and Reproduction
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• v.20 no.4
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• pp.297-304
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• 2016

Lectins belong to the pattern-recognition receptors (PRRs) class and play important roles in the recognition and elimination of pathogens via the innate immune system. Recently, it was reported that lily-type lectin-1 is involved when a pathogen attacks in the early immune response of fish. However, this study is limited to information that the lectin is involved in the innate immune response against viral infection. In the present study, the lily-type lectin-2 and -3 of Oplegnathus fasciatus (OfLTL-2 and 3) have been presented to be included B-lectin domain and two D-mannose binding sites in the amino acid sequence that an important feature for the fundamental structure. To investigate the functional properties of OfLTLs, the tissue distribution in the healthy rock bream and temporal expression during early developmental stage analysis are performed using quantitative real-time PCR. OfLTL-2 and 3 are predominantly expressed in the liver and skin, but rarely expressed in other organ. Also, the transcripts of OfLTLs are not expressed during the early developmental stage but its transcripts are increased after immune-related organs which are fully formed. In the challenge experiment with RBIV (rock bream iridovirus), the expression of OfLTLs was increased much more strongly in the late response than the early, unlike previously known. These results suggest that OfLTLs are specifically expressed in the immune-related tissues when those organs are fully formed and it can be inferred that the more intensively involved in the second half to the virus infection.

• Reproductive and Developmental Biology
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• v.35 no.4
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• pp.399-405
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• 2011

The number of abandoned dogs is increasing with the worsening of the economy and the rising of feed value. It was becoming a serious social problem because of the disease transmission and destruction of natural ecosystems by abandoned dogs been wild animal. In order to solve these problems, companion dogs necessary to secure its own genetic information and to establish the systematic tracking system. Using multiplex-PCR method with 27 microsatellite marker (MS marker) divided 3 set, various alleles occurring to 6 dog breed (Labrador Retriever, German Shepherd, English Springer Spaniel, Belgian Malinois, Jindo Dog, PoongSan Dog) make use of markers to determine allele frequency and heterozygosity. MS marker FH2834 and FH2790 have only two allele and most were found in 13 alleles at FH3381 and FH3399. Average heterozygosity of MS marker is 0.534 and especially, heterozygosity represented the highest value of 0.765 at FH3381. So, it was recognized appropriate allele frequency for individual identification and paternity diagnosis in companion dogs. Using multiplex-PCR method with MS marker, various alleles occurring to dog breed make use of markers to deter mine individual identification and paternity diagnosis, traits associated biomarkers and breed-specific marker for faster, more accurate and ways to reduce the analysis cost. Based on this result, a scientific basis was established to the existing pedigree data by applying genetics additionally. Animal registration system is expected to be conducted nationwide in future. The method expects to very useful this system.

• Reproductive and Developmental Biology
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• v.32 no.3
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• pp.193-198
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• 2008

The current study was designed to extend the technique of spermatogonial transplantation to economically important pig model We evaluated the efficiency of pig to pig transplantation. Donor testis cells were harvested from testes obtained at castration of 10- to 14-day-old boars and were labeled with fluorescent marker(PKH26) before transplantation. The presence of infused dye or labeled pig testicular cells was confirmed in the seminiferous tubules from recipient pig. The most effective procedure of intratubular germ cell transfer was to insert an fine needle ($21{\sim}25$ gauge) through the cauda epididymis and testis into the rete testis under ultrasound guidance. Infusion of $5{\sim}7ml$ of dye solution or cell suspension could fill the rete and up to 50% of seminiferous tubules of 14-week-old boars. Testis were examined for the presence and localization of labeled donor cells immediately after transplantation and labeled donor cells were found in numerous seminiferous tubules from recipient pig testes. These results indicate that germ cell transplantation is feasible in recipient pig testis. This study represents successful spermatogonial transplantation between individual animals in a livestock species.

• Reproductive and Developmental Biology
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• v.41 no.1
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• pp.1-6
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• 2017

In all mammalian species, progesterone is essential to both the preparation for, and maintenance of, pregnancy. The $20{\alpha}$-hydroxysteroid dehydrogenase ($20{\alpha}$-HSD) enzyme predominantly converts progesterone into its biologically inactive form $20{\alpha}$-hydroxyprogesterone, thereby regulating its activity. Thus, to directly assess sexual maturation in the MediKinetics $micropig^{(R)}$, we analyzed the concentration of the steroid hormones progesterone and estradiol during the estrous cycle. Our results show that the progesterone level exhibited by the analyzed $micorpig^{(R)}$ was low at the beginning of the estrous cycle, and then abruptly increased to $30.32{\pm}10.0ng/mL$ and $46.37{\pm}11.0ng/mL$ by days 9 and 11 of the cycle, respectively. It reached the highest level $55.87{\pm}3.5ng/mL$ on day 13 of the estrous cycle, before decreasing to $46.58{\pm}13.1ng/mL$ and $10.0{\pm}7.6ng/mL$ by days 15 and 17 of the cycle, respectively. In contrast, the estradiol level was shown to be highest ($27.13{\pm}11.2ng/mL$) at the initiation of the estrous cycle, after which point it decreased to $13.29{\pm}6.5ng/mL$ and $10.94{\pm}5.9ng/mL$ by days 4 and 5 of the estrous cycle, respectively. By day 17 of the estrous cycle, the estradiol level decreased to $4.13{\pm}7.6ng/mL$. We anticipate that these results will provide useful information to enable the study of human ovulation and reproductive physiology using the MediKinetics $micoripig^{(R)}$ as a model system. We recommend further investigation to elucidate the functional mechanisms underlying the regulation of sexual maturation in the MediKinetics $micropig^{(R)}$.

• Reproductive and Developmental Biology
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• v.31 no.3
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• pp.181-186
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• 2007

Inhibitor of DNA binding protein or inhibitor of differentiation(Id) is largely considered as positive and/or negative regulators of proliferation, differentiation, angiogeneisis, and apoptosis. The four Id genes(Id1, Id2, Id3, and Id4) were known in mammals. However, little is known about the expression and function of these genes in reproductive physiology. Among them, this study was conducted to analyze the expression pattern of Id3 mRNA on folliculogenesis in rat ovary. After PMSG administration, the ovaries were obtained at 3, 6, 12, 24, 36, and 48hrs, fixed, dehydrated, and paraffin embedded. For in situ hybridization, anti-sense and sense Id3 cRNA probes were prepared and applied to the ovarian section. The ovarian sections were coated with NTB-2 emulsion. After that, the slides were developed and counterstained with hematoxylin and eosin staining. The hybridization signal was estimated on a scale of 1+ to 4+. In oocyte, the intensity of Id3 mRNA in primordial and primary follicles was scored at ${\geq}2+$, but the intensity was less than 1+ in secondary, dominant, and preovulatory follicles. In granulosa cells, the Id3 mRNA was strongly expressed(3+ or 4+) in dominant and preovulatory follicles. Taken together, Id3 mRNA was expressed specifically at follicle stages and follicular tissue and might be closely related with follicle development.

• Journal of Conservation Science
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• v.33 no.5
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• pp.355-362
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• 2017

The Nongso tomb of Sunchang was built in a relatively deep place; hence there was little damage from grave robbers. The tomb was completely filled with a large amount of charcoal, and therefore the wooden coffin was excavated in relatively good condition. On the basis of the structure of the tombs, excavated artifacts, and radiocarbon dating results, the tomb is estimated to be from between the late Goryeo and the early Joseon period. The wooden coffin excavated is double-layered structures consisting of an outer coffin and an inner coffin. The outside of the wooden coffin is thickly lacquered and decorated with yellow letters and white motifs. An analysis of the pigments' components revealed that the major component of the letters was gold (Au) and the major component of the motifs was silver (Ag). The coffin lacquer had three layers: a pigment layer, a yellowish-brown layer, and a black layer. The wooden bases of the coffins were painted with a black substance, such as soot, as mineral elements were not detected in the black layer. The yellowish-brown layer is presumed to be refined lacquer. From the analysis of the structure of the layers and pigments, we can estimate the method was adopted for making lacquer for wooden coffin. It is assumed that the method used gold leaf and gold powder. The form of the pigment and the internal structure are likely to be gold leaf, but the shape of the surface letters appears to have been formed using gold powder. This study will serve as important information for understanding lacquer making techniques at the time of the tombs' construction by confirming the making method through reproduction experiments using gold leaf and gold powder.