• Journal of Information Technology Applications and Management
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• v.31 no.1
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• pp.113-122
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• 2024

This comprehensive study delves into the analysis of user review data across various metaverse platforms, employing advanced text mining techniques such as TF-IDF and Word2Vec to gain insights into user perceptions. The primary objective is to uncover the factors that contribute to user satisfaction and dissatisfaction, thereby providing a nuanced understanding of user experiences in the metaverse. Through TF-IDF analysis, the research identifies key words and phrases frequently mentioned in user reviews, highlighting aspects that resonate positively with users, such as the ability to engage in creative activities and social interactions within these virtual environments. Word2Vec analysis further enriches this understanding by revealing the contextual relationships between words, offering a deeper insight into user sentiments and the specific features that enhance their engagement with the platforms. A significant finding of this study is the identification of common grievances among users, particularly related to the processes of refunds and login, which point to broader issues within payment systems and user interface designs across platforms. These insights are critical for developers and operators of metaverse platforms, suggesting a focused approach towards enhancing user experiences by amplifying positive aspects. The research underscores the importance of continuous improvement in user interface design and the transparency of payment systems to foster a loyal user base. By providing a comprehensive analysis of user reviews, this study offers valuable guidance for the strategic development and optimization of metaverse platforms, ensuring they remain responsive to user needs and continue to evolve as vibrant, engaging virtual environments.

• Journal of Microbiology and Biotechnology
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• v.33 no.12
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• pp.1595-1605
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• 2023

Dehydroquinate dehydratase (DHQD) catalyzes the conversion of 3-dehydroquinic acid (DHQ) into 3-dehydroshikimic acid in the mid stage of the shikimate pathway, which is essential for the biosynthesis of aromatic amino acids and folates. Here, we report two the crystal structures of type II DHQD (CgDHQD) derived from Corynebacterium glutamicum, which is a widely used industrial platform organism. We determined the structures for CgDHQD^WT with the citrate at a resolution of 1.80Å and CgDHQD^R19A with DHQ complexed forms at a resolution of 2.00 Å, respectively. The enzyme forms a homododecamer consisting of four trimers with three interfacial active sites. We identified the DHQ-binding site of CgDHQD and observed an unusual binding mode of citrate inhibitor in the site with a half-opened lid loop. A structural comparison of CgDHQD with a homolog derived from Streptomyces coelicolor revealed differences in the terminal regions, lid loop, and active site. Particularly, CgDHQD, including some Corynebacterium species, possesses a distinctive residue P105, which is not conserved in other DHQDs at the position near the 5-hydroxyl group of DHQ. Replacements of P105 with isoleucine and valine, conserved in other DHQDs, caused an approximately 70% decrease in the activity, but replacement of S103 with threonine (CgDHQD^S103T) caused a 10% increase in the activity. Our biochemical studies revealed the importance of key residues and enzyme kinetics for wild type and CgDHQD^S103T, explaining the effect of the variation. This structural and biochemical study provides valuable information for understanding the reaction efficiency that varies due to structural differences caused by the unique sequences of CgDHQD.

• Convergence Security Journal
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• v.23 no.4
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• pp.53-59
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• 2023

Various problems are occurring as teachers and student's parents communicate directly through mobile phones. In this study, a service model was proposed that allows teachers and student's parents to communicate through SNS platforms without knowing each other's mobile phone numbers. In the civil complaint communication service model proposed in this study provides, communication key sets are provided as public data, and a commonly used SNS platform uses the relevant relationship information to implement communication. This model also has expandability that can be applied not only to teachers, but also to ① officers who need to communicate with the parents of soldiers, ② nursing, health and nursing care personnel who frequently contact patient caregivers, and ③ welfare officials.

• Informatization Policy
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• v.31 no.1
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• pp.72-82
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• 2024

The presence of traditional media content on online platforms is one of the critical issues nowadays, and Article 17 of the European Media Freedom Act (EMFA) seeks to regulate this. However, it can be seen that the current version of the text is not yet free of flaws: both its harmonisation with the Digital Services Regulation, its use of definitions and the media fast track mechanism it contains would require careful legislative scrutiny before the final text is adopted. The article examines if the self-declaration procedure envisaged by the EMFA would create a loophole for rogue media actors and bring confusion at both the European and horizontal levels or if it would fit the original goal of the EMFA, which is to improve the functioning of the internal European media market and to reinforce the independent media.

• Journal of Information Technology Applications and Management
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• v.30 no.1
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• pp.115-126
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• 2023

In various fields such as art, design, music, film, sports, games, and fashion, NFTs (Non-Fungible Tokens) are creating new economic value through trading platforms dedicated to NFT art and content. In this article, I analyze the current state of blockchain technology and NFT art content in the context of an expanding market for blockchain-based NFT art content in the metaverse. I also propose several tasks based on the economic and industrial logic of technological innovation. The first task proposed is to integrate cultural arts on blockchain, metaverse, and NFT platforms through digital innovation, instead of separating or distinguishing between creative production and consumption. Before the COVID-19 pandemic, there was a clear separation between creators and consumers. However, with the rise of Web 3.0 platforms, any user can now create and own their own content. Therefore, it is important to promote a collaborative and integrated approach to cultural arts production and consumption in the blockchain and metaverse ecosystem. The second task proposed is to align the legal framework with blockchain-based technological innovation. The enactment and revision of relevant laws should focus on promoting the development of the NFT trading platform ecosystem, rather than merely regulating it for user protection. As blockchain-based technology continues to evolve, it is important that legal systems adapt to support and promote innovation in the space. This shift in focus can help create a more conducive environment for the growth of blockchain-based NFT platforms. The third task proposed is to integrate education on digital arts, including metaverse and NFT art contents, into the current curriculum. This education should focus on convergence and consilience, rather than merely mixing together humanities, technology, and arts. By integrating digital arts education into the curriculum, students can gain a more comprehensive understanding of the potential of blockchain-based technologies and NFT art. This article examines the digital technological innovation such as blockchain, metaverse, and NFT from an economic and industrial point of view. As a limitation of this research, the critical mind such as philosophical thinking or social criticism on technological innovation is left as a future task.

• Journal of Animal Science and Technology
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• v.66 no.4
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• pp.859-862
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• 2024

It has been reported that the administration of Limosilactobacillus fermentum alleviates diseases such as osteoporosis and colitis. In this study, we report the complete genome sequence of Limosilactobacillus fermentum KUFM407, a probiotic strain of LAB isolated from Korean traditional fermented food, Kimchi. Whole genome sequencing of L. fermentum KUFM407 was performed on the Illumina MiSeq and Oxford Nanopore MinION platform. The genome consisted of one circular chromosome (2,077,616 base pair [bp]) with a guanine cytosine (GC) content of 51.5% and one circular plasmid sequence (13,931 bp). Genome annotation identified 1,932 protein-coding genes, 15 rRNAs, and 58 tRNAs in the assembly. The function annotation of the predicted proteins revealed genes involved in the biosynthesis of bacteriocin and fatty acids. The complete genome of L. fermentum KUFM407 could provide valuable information for the development of new probiotic food and health supplements.

• Journal of Environmental Health Sciences
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• v.50 no.4
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• pp.237-256
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• 2024

Background: Human health and environment exposure assessments of chemicals are essential part for REACH and BPR as well as K-REACH and K-BPR. Several useful exposure assessment tools have been developed and updated to become extensively used during more than fifteen years of chemical registrations under REACH and their updates are still going on. Objectives: Evolution of regulatory tools for environment, workers and consumers exposure assessments under REACH is investigated focusing on why and how tools have been developed and updated for the future regulatory tools in Korea. Methods: REACH regulatory tools including EUSES, ECETOC TRA and CHESAR as well as built-in models SimpleTreat and SimpleBox were chosen with other frequently used Tier 1 and 2 tools. Available resources such as homepage information, background documents, related scientific reports, relevant journal publications, up-to-date lists of new version publications, release notes and user guides were reviewed extensively and summarized using easy-readable Tables and Figures. Results: SimpleTreat and SimpleBox are built-in models both for EUSES and ECETOC TRA (Environment). ECHA's CHESAR contains ECETOC TRA (Workers) and ECETOC TRA (Consumers) as well as EUSES and ECETOC TRA (Environment) for environment exposure assessment while results of Tier 2 Stoffenmanager and ConsExpoWeb can be imported. Evolution of CHESAR from version 1 (2010) to 3.8 (2023) has focused on the compatibility of frequent updates of IUCLID, importing functionality, editability, updated use maps, harmonised conditions of use as well as updates of the built-in tools evolved according to scientific development, refinements of the tool, increased conservatism and user-friendliness. CHESAR Platform 1.0 will soon be published to serve both for REACH and BPR. Conclusions: Updates of the tools can be successfully continued by transparency of the tools, participation of industry sectors for tool refinements and tool developers'/authorities' encouragements of partners/users to jointly innovate tools through scientific researches, tool validations and user feedback.

• The Journal of Pediatrics of Korean Medicine
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• v.38 no.3
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• pp.13-28
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• 2024

Objectives This study aimed to analyze registrations in the World Health Organization International Clinical Trials Registry Platform for children and adolescents with tension-type headaches. Methods We collected and analyzed information on the basic and clinical characteristics of patients who participated in related clinical trials. All relevant clinical trials registered on or before July 2, 2024 were included in this study. Results Twenty clinical trials were selected for the analysis. Behavioral therapy was the most common intervention (60%), followed by drug, device, and manual therapies. The type of headache was the most frequently mentioned inclusion criteria, noted in 70% of the patients. Outcome indicators included headache frequency and intensity, quality of life, daily functioning, and mood. Conclusions Further clinical trials should require informed consent, an appropriate research design, suitable controls, and clear presentation of diagnostic criteria for more accurate and ethical studies.

• Journal of the Korea Computer Graphics Society
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• v.30 no.3
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• pp.159-169
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• 2024

This paper proposes a new real-time fire monitoring and evacuation navigation system by integrating Augmented Reality (AR) technology with Internet of Things (IoT) technology. The proposed system collects temperature data through IoT temperature measurement devices installed in buildings and automatically transmits it to a MySQL cloud database via an IoT platform, enabling real-time and accurate data monitoring. Subsequently, the real-time IoT data is visualized on a 3D building model generated through Building Information Modeling (BIM), and the model is represented in the real world using AR technology, allowing intuitive identification of the fire origin. Furthermore, by utilizing Vuforia engine's Device Tracking and Area Targets features, the system tracks the user's real-time location and employs an enhanced A^* algorithm to find the optimal evacuation route among multiple exits. The paper evaluates the proposed system's practicality and demonstrates its effectiveness in rapid and safe evacuation through user experiments based on various virtual fire scenarios.

• International journal of advanced smart convergence
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• v.13 no.3
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• pp.287-299
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• 2024

Xiaohongshu, a community-centric social media platform, has pioneered a unique e-commerce model known as 'buyer commerce,' leveraging user-generated content (UGC). Distinctively, Xiaohongshu Live Commerce focuses on fostering deep user relationships and providing superior product and information services, crucial for sustained consumer engagement. This study investigates consumer behavior in purchasing health functional foods via Xiaohongshu Live Commerce, aiming to understand the determinants of continuous usage intention. A novel theoretical framework was devised by integrating the Expectation Confirmation Model (ECM) and the Task-Technology Fit (TTF) model. The research model scrutinizes the impact of Xiaohongshu Live Commerce characteristics, such as perceived usefulness and perceived online intimacy, on task-technology fit. Additionally, it examines the moderating role of perceived risk specific to health functional foods and the influence of expectation confirmation on perceived usefulness, online intimacy, and task-technology fit, alongside their effects on satisfaction and continuous usage intention. The findings reveal that expectation confirmation positively influences perceived usefulness, online intimacy, and task-technology fit. Perceived usefulness significantly enhances task-technology fit, while perceived online intimacy and risk do not significantly affect task-technology fit. Moreover, perceived usefulness and intimacy positively impact consumer satisfaction and continuous usage intention, with task-technology fit playing a pivotal role. Perceived risk moderates the relationship between perceived usefulness and task-technology fit. These insights suggest that companies can augment consumer satisfaction and continuous usage intentions by enhancing the perceived usefulness of technology, effectively managing perceived risks, and continually improving user experience