• Title/Summary/Keyword: Ineffectiveness

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Chlorte Reduction in $ClO_2$Prebleaching by the Addition of HClO Scavengers

  • Yoon, Byung-Ho;Lee, Myoung-Ku;Wang, Li-Jun
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2000.11a
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    • pp.15-21
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    • 2000
  • In chlorine dioxide delignification and bleaching the formation of chlorate is undesirable because it does not react with lignin and is harmful to the environment. Chlorate is mainly formed from the in-situ generated hypochlorus acid which is also the main reason for AOX formation. In previous literature scavengers of hypochlorous acid such as sulfamic aicd, DMSO, and hydrogen peroxide have been added to bleaching stages to reduce AOX formation but less attention has been paid to chlorate reduction. This paper thus focuses on the reduction of chlorate content caused by the following additives, sulfamic acid, DMSO, hydrogen peroxide, and oxalic acid. The results show that only sulfamic acid and DMSO reduce chlorate formation under our chlorine dioxide prebleaching conditions. Results by UV spectroscopy and pH adjustment show that scavengers react with hypochlorous acid much faster than with chlorine. Hydrogen peroxide and oxalic acid react with HClO/$Cl_2$much slower than DMSO and sulfamic acid do. The reason for the ineffectiveness of hydrogen peroxide and oxalic acid is ascribed to their slow reaction rates with HClO compared to that of chlorate formation. The fact that only 30-35% of the chlorate can be reduced by sulfamic acid and DMSO when charged in same mole ratio to chlorine dioxide, suggested that the reaction rate of DMSO and sulfamic acid with hypochlorous aicd are of the same magnitude as that of chlorate formation.

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Carboplatin and Doxorubicin in Treatment of Pediatric Osteosarcoma: A 9-year Single Institute Experience in the Northern Region of Thailand

  • Choeyprasert, Worawut;Natesirinilkul, Rungrote;Charoenkwan, Pimlak;Sittipreechacharn, Somjai
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.1101-1106
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    • 2013
  • Background: Osteosarcoma is the most common primary bone tumor in childhood and adolescence. Carboplatin, a platinum-derived agent, is used as neoadjuvant chemotherapy for pediatric osteosarcoma because of its anti-tumor activity and had low toxicity as compared to cisplatin. Objective: To determine demographic data, prognostic factors and outcome of childhood osteosarcoma treated with a carboplatin-based chemotherapeutic protocol at Chiang Mai University. Method: A retrospective analysis was conducted on 34 osteosarcoma patients aged less than 18 years and treated between 2003 and 2011. Results: Overall limb-salvage and amputation rates were 23.5% and 70.6%, respectively. With the mean follow-up time of 29.5 months (1.5-108.9), the Kaplan-Meier analysis for 3-year disease-free survival (DFS) and 3-year overall survival (OS) were $20.2{\pm}7.7%$ and $47.1{\pm}9.5%$ respectively. Patients who had initial pulmonary metastasis were at significantly greater risk for developing recurrence (p=0.02, OR=7; 1.2-40.1) and had a tendency to have lower 3-year OS compared to those without initial pulmonary metastasis ($28.1{\pm}13%$, $63.1{\pm}12.3%$, respectively, p=0.202). On univariate analysis, age at diagnosis >14 years and patients who were declined surgery were significantly associated with lower 3-year OS (p=0.008 and <0.05, respectively). However, age at diagnosis, sex, tumor size and histological subtypes were not found to significantly affect recurrence or survival. Conclusions: In our study, the survival rate was far lower than those reported from developed countries. These might indicate the ineffectiveness of carboplatin in combination with doxorubicin as frontline treatment of pediatric osteosarcoma, especially in those with initial pulmonary metastasis. Refinement in risk and treatment stratification and dose intensification for pediatric osteosarcoma constitutes a future challenge to improve outcomes, especially in metastatic patients who may need a more intensive regimen.

Cancer Care Management through a Mobile Phone Health Approach: Key Considerations

  • Mohammadzadeh, Niloofar;Safdari, Reza;Rahimi, Azin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.4961-4964
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    • 2013
  • Greater use of mobile phone devices seems inevitable because the health industry and cancer care are facing challenges such as resource constraints, rising care costs, the need for immediate access to healthcare data of types such as audio video texts for early detection and treatment of patients and increasing remote aids in telemedicine. Physicians, in order to study the causes of cancer, detect cancer earlier, act in prevention measures, determine the effectiveness of treatment and specify the reasons for the treatment ineffectiveness, need to access accurate, comprehensive and timely cancer data. Mobile devices provide opportunities and can play an important role in consulting, diagnosis, treatment, and quick access to health information. There easy carriage make them perfect tools for healthcare providers in cancer care management. Key factors in cancer care management systems through a mobile phone health approach must be considered such as human resources, confidentiality and privacy, legal and ethical issues, appropriate ICT and provider infrastructure and costs in general aspects and interoperability, human relationships, types of mobile devices and telecommunication related points in specific aspects. The successful implementation of mobile-based systems in cancer care management will constantly face many challenges. Hence, in applying mobile cancer care, involvement of users and considering their needs in all phases of project, providing adequate bandwidth, preparation of standard tools that provide maximum mobility and flexibility for users, decreasing obstacles to interrupt network communications, and using suitable communication protocols are essential. It is obvious that identifying and reducing barriers and strengthening the positive points will have a significant role in appropriate planning and promoting the achievements of mobile cancer care systems. The aim of this article is to explain key points which should be considered in designing appropriate mobile health systems in cancer care as an approach for improving cancer care management.

Resource Allocation in Spectrum Sharing ad-hoc Cognitive Radio Networks Based on Game Theory: An Overview

  • Abdul-Ghafoor, Omar B.;Ismail, Mahamod;Nordin, Rosdiadee;El-Saleh, Ayman Abd
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.7 no.12
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    • pp.2957-2986
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    • 2013
  • The traditional approach of fixed spectrum allocation to licensed networks has resulted in spectrum underutilisation. Cognitive radio technology is envisioned as a promising solution that can be used to resolve the ineffectiveness of the fixed spectrum allocation policy by accessing the underutilised spectrum of existing technologies opportunistically. The implementation of cognitive radio networks (CRNs) faces distinct challenges due to the fact that two systems (i.e., cognitive radio (CR) and primary users (PUs)) with conflicting interests interact with each other. Specially, in self-organised systems such as ad-hoc CRNs (AHCRNs), the coordination of spectrum access introduces challenges to researchers due to rapid utilisation changes in the available spectrum, as well as the multi-hop nature of ad-hoc networks, which creates additional challenges in the analysis of resource allocation (e.g., power control, channel and rate allocation). Instead, game theory has been adopted as a powerful mathematical tool in analysing and modelling the interaction processes of AHCRNs. In this survey, we first review the most fundamental concepts and architectures of CRNs and AHCRNs. We then introduce the concepts of game theory, utility function, Nash equilibrium and pricing techniques. Finally, we survey the recent literature on the game theoretic analysis of AHCRNs, highlighting its applicability to the physical layer PHY, the MAC layer and the network layer.

Why Firms Need to Bring in Enterprise Architecture and How it ould be Introduced? (Enterprise Architecture의 필요성 및 추진방안)

  • Kim, Sung-Kun;Park, Hyun-Joo
    • Information Systems Review
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    • v.4 no.2
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    • pp.19-40
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    • 2002
  • Many firms have had a passion for IT investment for years. Despite such a continuing investment in IT, the application of newer technologies to business work doesn't guarantee a great success. Some IT projects were doomed to failure or ineffectiveness. What could we do to lead IT project to the territory of effectiveness? One plausible and inevitable avenue is enterprise architecture (EA), which requires one to first come up with a simplified view of the complex entity to be designed and then proceed to design and develop it as directed by the architecture. Though there have been more materials on such EA work and real cases, there still exist a doubt about why EA is needed and how a firm can introduce it. This article first presents a structured understanding about EA and then describes the necessity, and the introducing ways of EA.

Causes of Construction Delays of Apartment Construction Projects: Comparative Analysis between Vietnam and Korea

  • Kim, Young-Mok;Kim, Soo-Yong;Luu, Truong-Van
    • Korean Journal of Construction Engineering and Management
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    • v.9 no.5
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    • pp.214-226
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    • 2008
  • Construction delay caused considerable losses to project parties. Avoiding construction delays is important to save costs for project stakeholders. The main objective of this paper is to identify major causes of construction delays of apartment construction projects in Vietnam. Sixteen causes of delay were identified through a questionnaire survey of 166 professionals. Factor analysis was employed to categorize these causes. The results of the survey revealed the main causes of delay of apartment projects in Vietnam are: (1) owner's and contractor'S financial difficulties; (2) lack of experienced contractors; (3) late delivery of materials; (4) late construction site handover; (5) owner's late payments for completed works; (6) low bid prices; (7) inappropriate construction method; and (8) defective works and unnecessary reworks. Factor analysis uncovered that causes of delay can be grouped under five categories labeled the five INs: incompetence, ineffectiveness, inadequateness, inapplicableness and inconceivableness. Comparative analysis between the Vietnam construction industry (VCI) and the Korea construction industry (KCI) has been performed to infer valuable lessons for researchers and practitioners in the VCI and the KCI. Comparative analysis indicated that main causes of delay in the VCI somewhat differ from main causes of delay in the KCI. However, "contractor'S financial difficulties", "late construction site handover", "unnecessary rework", "incapable designers", "site clearance difficulties" are common causes of delay in the VCI as well as the KCI. The findings of this research can be used as a guideline to overcome problems in the VCI as well as in other construction industries. Since Korea has emerged as the first largest foreign investor in Vietnam, the results of this study may be useful not only to practitioners and researchers in Vietnam but also to participants in Korea.

A Study of the Design of Social Safety Net in Korea -with Special Emphasis on the Livelihood Aid Programme- (고실업 저성장 시대의 사회적 안전망 구축에 관한 연구 - 생활보호제도의 개선을 중심으로 -)

  • Moon, Jin-Yong
    • Korean Journal of Social Welfare
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    • v.35
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    • pp.179-203
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    • 1998
  • Since the end of 1997, the Korean economy has been in deep recession; the unemployment rate has rocketed to 6.7% and the economic growth rate has dropped to -3.8% in the first quarter of 1998. Facing with this mass unemployment, the Korean Government launched comprehensive countermeasures against mass unemployment.. However, these have been in severe criticism from the outset on account of ineffectiveness and impracticability. It is in this regard that this paper purports to design a socially acceptable and financially feasible social safety net by reforming the Livelihood Aid Programme. For this purpose, chapter 3 defines the concept of social safety net, and chapter 4 reviews the social safety net programmes sponsored by World Bank and IMF in the Third World countries and Eastern European countries. Chapter 5 proposes the Three Step Approach in designing the social safety net in Korea.

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The Clinical Study of the Efficacy of Lizhongtang plus Baidusan(理中湯合敗毒散) on Allergic Rhinitis (理中湯合敗毒散의 알레르기성 비염 치료효과에 대한 임상적 연구)

  • Lee, Sang-moon;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.16 no.3
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    • pp.185-199
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    • 2003
  • Objectives : The purpose of this clinical report was to estimate the efficacy of Lizhongtang plus Baidusan(理中湯合敗毒散) on allergic rhinitis. Methods : We prescribed Lizhongtang plus Baidusan(理中湯合敗毒散) for 15 patients who visited Kabsan oriental clinic with allergic rhinitis. We inquired into distribution of age, case history period, improvement of symptoms, etc. We used the statistical methods of student t-test in order to analysis of the different of symptom before and after treatment(p 〈0.05). Results : 1. The distribution of sex & age was as follows; Total patient were women. 10-19 years 2 cases, , 30-39 years 5 cases, 40-49 years 6 cases and 50-59 years 2 cases. 2. The case of history period was as follows; under a year 1 case, 1-3 years 3 cases, 3-5 years 2 cases, 5-10 years 4 cases and over 10 years 5 cases. 3. The amount of herbal medicine they took as follows: 1 je(劑) 1 case, 2 je(劑) 7 cases, 3 je(劑) 5 cases and 4 je(劑) 2 cases. 4. The frequency of acupuncture and moxibustion was as follows; under 5 times 1 case, 6-10 times 10 cases, 11-15 times 3 cases, over 16 times 1 case. 5. The nasal symptoms except the nasal mucosa color(pale) were improved significantly after treatment(p 〈0.05). 6 The general symptoms except menstruation pain were improved significantly after treatment(p 〈0.05). 7. The curative influence of rhinitis by Lizhongtang plus Baidusan(理中湯合敗毒散) was as follows excellent 2 cases. good 11 cases, ineffectiveness 2 cases. Conclusion: If we administer Lizhongtang plus Baidusan(理中湯合敗毒散) to allergic rhinitis patients with cold in the Zhong Jiao of deficiency type (中焦虛寒), it improves not only allergic symptoms such as the watery rhinorrhea, turbinate swelling, sneeze, nasal obstruction, etc but also coldness of the limbs(手足冷症), dyspepsia, dysmenorrhea, etc. Therefore, we consider that administration of Lizhongtang plus Baidusan(理中湯合敗毒散) to allergic rhinitis patients with cold in the Zhong Jiao of deficiency type (中焦虛寒) improves in quality of life, as removes inconvenience of life and stress.

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A Study on the Korean Fishery Management System and TAC System Implementation on Issues of the New Ocean Regime (신해양질서의 어업관리체계와 TAC 제도 도입에 관한 연구)

  • 이상고
    • The Journal of Fisheries Business Administration
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    • v.30 no.1
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    • pp.1-29
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    • 1999
  • When the international fisheries order changes following the UN Law of the Sea, the new regional fisheries order is forming among East North Asian states and era of Economic Zones is really coming. In those changes of foreign and domestic fisheries environment, to maintain sustainable growth of the industry in 21st century the North East Asian states plot adjustments to fisheries management, such as introduction of the TAC system and others. The TAC seems to be an appropriate systematic response especially because traditional functions of fisheries management have already demonstrated their limits in regards to fisheries sustainable development. Introduction of the TAC to the North East Asian fisheries not only resolves the inability of traditional fisheries management to develop the industry consequently, but also strengthens the EEZ and existing marine management systems. However, the TAC was born by thewestern industrial mentality, still contains persistent mistakes and is difficult to change. Therefore, its introduction to and implication in North East Asian region might cause numerous problems. From this point of view, introduction of the TAC system will disregard peculiarities of North East Asian fisheries, so main efforts should be concentrated on improving the functions of existing system via consecutive step-by-step approach. In addition, the TAC should be grafted into the existing fisheries system through cooperative management system, creating stable systematic ground and considering scientific and fisheries motives. Especially, TAC system, unlike the traditional fisheries' management system, is scientific, being systematically developed one, and needs to be gradually installed, considering its systematic character. Therefore, the TAC should better be introduced by systematic and scientific approaches, paying more attention to strengthening the existing fisheries system, but not immediately and in the form it is right now. Concluding, introduction of the TAC can not be made considering the outward factors deriving from the UN Law of the Sea without corrections.'h overcome limitations and ineffectiveness of traditional fisheries, most efforts should be concentrated on basic revision of 21st centuries' fisheries and strengthening the functions of traditional fisheries aimed to develop the leading business of marine industries.

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RESEARCH ON THE BAMBOO IN KOREA (Ⅷ) On the Effectiveness of Fertilizers by kind upon the New and Old Bamboos (한국산의 죽류에 관한 연구 (제8보) 신죽과 구죽에 있어서 비료의 종류에 따르는 효율성에 대하여)

  • Chong, Hyon-Pae
    • Journal of Plant Biology
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    • v.9 no.1_2
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    • pp.25-30
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    • 1966
  • The writer presented in the report 7th of this series(Chong, 1959. '62 a.b. '64, '65) the result of fertlizer application on Sasamorpha purpurascens var. borealis with regards to soil conditions, climate, planting position etc. and this report is on the effectiveness of fertilizers by kinds of the new (1-year old) and old(3-to 4 years old) Phyllostachys retticulata. The ineffectiveness of fertilizers for old bamboos aged more than 8-years old has been reported previously. The study site was chosen in a bamboo groven situated at Hyunnae Ri, Okkye Myun, Myungju Gun, Kangwon Do. Each plot was so designed that only one individual remained at the center of a circular area with a dimeter of meters by eliminating the clums and severing the rhizomes, of other individuals around it. And, for the fertilizer test, 10 individuals(the new and old: 5 to 5) were observed per kind of fertilizer used; thus marking the total number of 160 plots in all. The second part of this study was conducted for the potted individuals which numbered 48, successfully established ones out of 55 the transplanted to pots. The 48 were divided into 8 treatments: whole fertilization (NPK+compost+human manure); NPK; N; K; Human manure; compost; and the control. Amoung of fertilizers applied was 200 grams for the natural plots and 100 grams for pot; it continued for 3 years and applied twice a year (spring and summer) following the theory of Dr. Koichi-ro Ueda(1954, '60 a.b.). Measurements were taken in August each year. The resutls were confirming the fact that the bamboos require a great deal of fertilizers. The results show the following points: 1) Fertilizers were more effective in the 3 to 4 year old bamboos. 2) The order of effectiveness of fertilizers by kind was the whole fertilization, NPK, and N treatments for Phyllostachys reticulata. 3) Organic matter in addition to commercial fertilizers showed better result than the soil application of the latter due to better soil aeration.

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