• Structural Engineering and Mechanics
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• 제70권4호
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• pp.479-497
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• 2019

In the current code design, the use of a uniform internal pressure coefficient of cooling towers as internal suction cannot reflect the 3D characteristics of flow field inside the tower body with different ventilation rate of shutters. Moreover, extreme weather such as heavy rain also has a direct impact on aerodynamic force on the internal surface and changes the turbulence effect of pulsating wind. In this study, the world's tallest cooling tower under construction, which stands 210m, is taken as the research object. The algorithm for two-way coupling between wind and rain is adopted. Simulation of wind field and raindrops is performed iteratively using continuous phase and discrete phase models, respectively, under the general principles of computational fluid dynamics (CFD). Firstly, the rule of influence of 9 combinations of wind speed and rainfall intensity on the volume of wind-driven rain, additional action force of raindrops and equivalent internal pressure coefficient of the tower body is analyzed. The combination of wind velocity and rainfall intensity that is most unfavorable to the cooling tower in terms of distribution of internal pressure coefficient is identified. On this basis, the wind/rain loads, distribution of aerodynamic force and working mechanism of internal pressures of the cooling tower under the most unfavorable working condition are compared between the four ventilation rates of shutters (0%, 15%, 30% and 100%). The results show that the amount of raindrops captured by the internal surface of the tower decreases as the wind velocity increases, and increases along with the rainfall intensity and ventilation rate of the shutters. The maximum value of rain-induced pressure coefficient is 0.013. The research findings lay the basis for determining the precise values of internal surface loads of cooling tower under extreme weather conditions.

• Tribology and Lubricants
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• 제37권2호
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• pp.71-76
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• 2021

As opposed to using fossil fuels, we need to use eco-friendly resources such as sunlight, raindrops and wind to produce electricity and combat environmental pollution. A triboelectric nanogenerator (TENG) is a device that converts mechanical energy into electricity by inducing repetitive contact and separation of two dissimilar materials. During the contact and separation processes, electron flow occurs owing to a change in electric potential of the contacting surface caused by contact electrification and electrostatic induction mechanisms. A solid-solid contact TENG is widely known, but it is possible to generate electricity via liquid-solid contact. Therefore, by designing a hydrophobic TENG, we can gather electricity from raindrop energy in a feasible manner. To fabricate the superhydrophobic surface of TENGs, we employ a dip coating technique to synthesize an octadecylamine (ODA)- and polydimethylsiloxane (PDMS)-based coating on polyethylene terephthalate (PET). The synthesized coating exhibits superhydrophobicity with a contact angle greater than 150° and generates a current of 2.2 ㎂/L while water droplets fall onto it continuously. Hence, we prepare a box-type TENG, with the ODA/PDMS coating deposited on the inside, and place a 1.5 mL water droplet into it. Resultantly, we confirm that the induced vibration causes continuous impacts between the ODA/PDMS coating and the water, generating approximately 100 pA for each impact.

• 기록학연구
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• 제62호
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• pp.77-107
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• 2019

공공기관의 특성을 반영한 기록물관리의 체계를 구축하고, 기록물관리기관의 전문성 독립성을 강화하기 위해서는 기록물관리기관에 전문인력의 확충이 시급하다는 요구는 지속적으로 제기되어 왔다. 그러나 "공공기록물법"이 제시하고 있는 현행 기록물관리 전문 인력 배치기준은 명확하지 않아 기록물관리 업무에 필요한 인력을 확보하는데 어려움을 겪어왔다. 이에 본 연구는 첫째, 기록물관리기관의 업무 모델을 개발하고, 둘째, 개발된 업무 모델에 따라 기록물관리 업무량을 산출하고 해당 업무량을 처리하는데 소요되는 적정 인력을 산정하였다. 셋째, 이러한 결과를 종합하여 새로운 기록물관리 전문 인력의 배치기준을 제시하였다.

• Smart Structures and Systems
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• 제23권6호
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• pp.565-577
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• 2019

One of the most effective countermeasures for mitigating cable vibration is to install mechanical dampers near the anchorage of the cable. Most of the dampers used in the field are so-called passive dampers where their parameters cannot be changed once designed. The parameters of passive dampers are usually determined based on the optimal damper force obtained from the universal design curve for linear dampers, which will provide a maximum additional damping for the cable. As the optimal damper force is chosen based on a predetermined principal vibration mode, passive dampers will be most effective if cable undergoes single-mode vibration where the vibration mode is the same as the principal mode used in the design. However, in the actual engineering practice, multi-mode vibrations are often observed for cables. Therefore, it is desirable to have dampers that can suppress different modes of cable vibrations simultaneously. In this paper, MR dampers are proposed for controlling multi-mode cable vibrations, because of its ability to change parameters and its adaptability of active control without inquiring large power resources. Although the highly nonlinear feature of the MR material leads to a relatively complex representation of its mathematical model, effective control strategies can still be derived for suppressing multi-mode cable vibrations based on nonlinear modelling, as proposed in this paper. Firstly, the nonlinear Bouc-wen model is employed to accurately portray the salient characteristics of the MR damper. Then, the desired optimal damper force is determined from the universal design curve of friction dampers. Finally, the input voltage (current) of MR damper corresponding to the desired optimal damper force is calculated from the nonlinear Bouc-wen model of the damper using a piecewise linear interpolation scheme. Numerical simulations are carried out to validate the effectiveness of the proposed control algorithm for mitigating multi-mode cable vibrations induced by different external excitations.

• Molecules and Cells
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• 제42권10호
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• pp.702-710
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• 2019

Neuroinflammation is an important contributor to the pathogenesis of neurodegenerative disorders including Parkinson's disease (PD). We previously reported that our novel synthetic compound KMS99220 has a good pharmacokinetic profile, enters the brain, exerts neuroprotective effect, and inhibits $NF{\kappa}B$ activation. To further assess the utility of KMS99220 as a potential therapeutic agent for PD, we tested whether KMS99220 exerts an anti-inflammatory effect in vivo and examined the molecular mechanism mediating this phenomenon. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice, oral administration of KMS99220 attenuated microglial activation and decreased the levels of inducible nitric oxide synthase and interleukin 1 beta ($IL-1{\beta}$) in the nigrostriatal system. In lipopolysaccharide (LPS)-challenged BV-2 microglial cells, KMS99220 suppressed the production and expression of $IL-1{\beta}$. In the activated microglia, KMS99220 reduced the phosphorylation of $I{\kappa}B$ kinase, c-Jun N-terminal kinase, and p38 MAP kinase; this effect was mediated by heme oxygenase-1 (HO-1), as both gene silencing and pharmacological inhibition of HO-1 abolished the effect of KMS99220. KMS99220 induced nuclear translocation of the transcription factor Nrf2 and expression of the Nrf2 target genes including HO-1. Together with our earlier findings, our current results show that KMS99220 may be a potential therapeutic agent for neuroinflammation-related neurodegenerative diseases such as PD.

• 한국기계가공학회지
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• 제20권2호
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• pp.93-100
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• 2021

Copper sheets has been used widely in electric and electron industry fields because they have good electric and heat conduction property of the material. And, in order to bond copper material, a kind of soldering process is generally used. But, because it is difficult to bond by soldering between overlapped thin copper sheets, so, another kind of brazing bonding process can be used in that case. But, because the brazing process needs wide bonding area, it needs heat treatment process in electric furnace. Generally, for spot welding of sheets, a conventional electric Resistance Spot Welding process(RSW) has been used, it has welding characteristics using contact resistance heating induced by electric current flow between sheets. But, because copper sheets has the low electric resistance, it is difficult to weld by electric resistance spot welding. So, in this study, an electric Resistance heated Surface Friction Spot Welding process(RSFSW) is suggested and is testified for the spot welding ability of thin copper sheets. It is known from the experimental results and simulation that the suggested spot welding process will be able to improve the spot welding ability of copper sheets by the combined three kinds of heating generated by surface friction by rotating pin, and conducted from heated steel electrode, and generated by contact resistance of electricity.

• Current Optics and Photonics
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• 제6권6호
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• pp.550-564
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• 2022

Optical microscopy is a useful tool for study in the biological sciences. With an optical microscope, we can observe the micro world of life such as tissues, cells, and proteins. A fluorescent dye or a fluorescent protein provides an opportunity to mark a specific target in the crowd of biological samples, so that an image of a specific target can be observed by an optical microscope. The optical microscope, however, is constrained in resolution due to diffraction limit. Super-resolution microscopy made a breakthrough with this diffraction limit. Using a super-resolution microscope, many biomolecules are observed beyond the diffraction limit in cells. In the case of volumetric imaging, the super-resolution techniques are only applied to a limited area due to long imaging time, multiple scattering of photons, and sample-induced aberration in deep tissue. In this article, we review recent advances in super-resolution microscopy for volumetric imaging. The super-resolution techniques have been integrated with various modalities, such as a line-scan confocal microscope, a spinning disk confocal microscope, a light sheet microscope, and point spread function engineering. Super-resolution microscopy combined with adaptive optics by compensating for wave distortions is a promising method for deep tissue imaging and biomedical applications.

• Earthquakes and Structures
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• 제20권1호
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• pp.1-12
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• 2021

The occurrence of progressive collapse induced by the removal of the vertical load-bearing element in the structure, because of fire or earthquake, has been a significant challenge between structural engineers. Progressive collapse is defined as the complete failure or failure of a part of the structure, initiating with a local rupture in a part of the building and can threaten the stability of the structure. In the current study, the behavior of the structures equipped with a cylindrical friction damper, when the vertical load-bearing elements are eliminated, is considered in two cases: 1-The load-bearing element is removed under the gravity load, and 2-The load-bearing element is removed due to the earthquake lateral forces. In order to obtain a generalized result in the seismic case, 22 pair motions presented in FEMA p 695 are applied to the structures. The study has been conducted using the vertical push down analysis for the case (1), and the nonlinear time-history analysis for the second case using OpenSEES software for 5,10, and 15-story steel frames. Results indicate that, in the first case, the load coefficient, and accordingly the strength of the structure equipped with cylindrical friction dampers are increased considerably. Furthermore, the results from the second case demonstrate that the displacements, and consequently the forces imposed to the structure in the buildings equipped with the cylindrical friction damper substantially was reduced. An optimum slip load is defined in the friction dampers, which permits the damper to start its frictional damping from this threshold load. Therefore, the optimum slip load of the damper is calculated and discussed for both cases.

• 한국어병학회지
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• 제34권1호
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• pp.55-61
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• 2021

One of the major problems in fish production is that parasite-induced episodes of disease can result in significant impacts to the health of stock, mortalities and, economical losses. Seabreams are economically important fish in both the capture fishery and aquaculture sectors in Oman and represent potential species for aquaculture. The current study set out to investigate infection of polyopisthocotylean monogeneans on the gills of wild goldlined seabream, Rhabdosargus sarba, caught from Musairah region in Oman. The prevalence, mean intensity and abundance of polyopisthocotyleans on 145 fish was found to be 52.41%, 5.65 and 3.04, respectively. Three species of microcotylid parasite were isolated, one being Atrispinum acarne while the remaining two species require further study to identify them. There was no significant difference in the infection rate between host sex, however, parasite burdens were higher on larger sized fish (p<0.05) and were found to favour the first gill arch (p< 0.05). The study found that the sample of Rhabdosargus sarba landed in the waters around Musairah are heavily infected, with a predominantly immature population of microcotylids. Further work is required to better understand the potential risk each species poses to the health of its host before a decision is made on the suitability of new candidate fish species for commercial aquaculture.

• 공업화학
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• 제22권5호
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• pp.447-452
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• 2011

석유자원의 고갈이 에너지 및 화학원료물질로 재생 가능한 바이오매스의 이용성을 증가시키고 있다. 본 총설에서는 바이오에너지 및 바이오화학원료인 C4-C6 생산에 관해 논하고자 한다. 주요한 C4 물질인 n-butanol과 n-butyric acid를 다량 생산하는 미생물은 Clostridium tyrobutyricum, Clostridium beijerinckii, Clostridium acetobutylicum이다. 대표적인 C6 물질인 n-hexanoic acid는 Clostridium kluyveri와 Megasphaera elsdenii가 다량 생산한다. 미생물 발효에 의해 보고된 n-butanol, n-butyric acid, n-hexanoic acid의 최대 생산량은 각각 21, 55, 19 g/L이었다. 배양과정에서 이들 생산물의 제거는 최종산물억제의 감소로 미생물에 의한 n-butanol, n-butyric acid, n-hexanoic acid의 생산량을 증가시켰다. 특히 C6 물질인 n-hexanoic acid는 n-hexanol로 될 수 있는 고 부가가치 물질로 생물학적 생산 연구가 꾸준히 진행 중인데, 신규한 미생물인 Clostridium sp. BS1은 galactitol을 이용하여 5 g/L의 n-hexanoic acid를 생산하였다.