• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.4889-4895
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• 2012

Background and Aim: The incidence of extra nodal non Hodgkin lymphoma (ENL) is rising throughout the world. However, data regarding ENL as a group is limited. The aim was to study the epidemiological and histomorphological trends of primary ENL (pENL) in India. Material and Methods: The biopsy materials from sixty eight patients with pENL (45 male, 23 female, M:F= 1.9:1), diagnosed over a five year period (2005-2009), were analysed and pathologically reclassified according to the World Health Organization (WHO) classification, 2008 criteria. Results: Primary extra nodal non Hodgkin lymphomas constituted 22.0% (68/308) of all non Hodgkin lymphomas (NHL). The mean age at presentation for pENL and primary nodal NHL was 43 years and 58 years, respectively with a male predilection (M: F=2:1). Central nervous system (CNS) constituted the most common extranodal site (20/68, 29.5%) followed by gastrointestinal tract (17/68, 25%), and nose/nasopharynx (8/68, 11.8%). Diffuse large B-cell lymphoma (DLBCL, not otherwise specified), extranodal marginal lymphoma of mucosa associated lymphoid tissue (MALT) type, and B cell NHL unclassified (U) were the three most common histological types observed. T-cell phenotype was rarely noted (4%). Follicular lymphomas and anaplastic large cell lymphoma, seen among nodal NHL, were absent at extra nodal sites. Majority (41/68, 60%) of the patients with pENL were immunocompetent and 55% were in stage I-II with favorable prognosis. Conclusion: Central nervous system was the most common site of ENL, followed by gastrointestinal tract. Majority of pENL occurred in immunocompetent hosts with a favorable prognosis.

• Strategy21
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• s.46
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• pp.159-204
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• 2020

This study is written to bring the proposal forward for the direction of south korean naval force. The political situation and the circumstance of the world, especially in the area of Pacific Ocean, are changing very rapidly. North Korea has been always the conventional existing intimidator for South Korea since the 6·25-War. Additionally, the strengthening movements of the national defense, which is easily noticed from China and Russia, is also an other part of intimidating countries against South Korea. Those three mentioned countries are continually developing the asymmetrical warfare systems, for example a strategic nuclear weapon. Since the Obama Administration, the Asia-Pacific Rebalancing-Strategy has been changed as an East Asian foreign policy. Nowadays, Trump Administration renamed the 'United States Pacific-Command' to 'United States Indo-Pacific Command'. The purpose of this is not only letting India to participate in american alliance, but also reducing an economic burden, which is often mentioned in USA. West Germany was located in the very similar geopolitical position during the Cold War just like South Korea these days. And that's why the strategy of West German Navy is worthy of notice for south korean naval force to decide its suitable strategy. Most of all, the two most important things to refer to this study are the plan to expand naval air force and the realistic political stand for us to take it. In conclusion, I laid an emphasis on maintenance of 'green-water-navy'. instead of selecting the strategy as a 'blue-water-navy'. The reason I would like to say, is that south korean navy is not available to hold the unnecessary war potential, just like Aircraft-Carrier. However, this is not meaning to let the expansion of naval force carelessly. We must search the best solution in order to maintain the firm peace within the situation. To fulfill this concept, it is mostly very important to maintain the stream of laying down a keel of destroyers, submarines and air-defense-missile, as well as the hight-tech software system, taking a survey of 4th industrial revolution. Research and development for the best solution of future aircraft by south korean navy is likewise necessary. Besides, we must also set the international diplomatic flexibly. As well as maintaining the relationship with US Forces, it is also very important to improve the relationship with other potential allied nation.

• Maritime Security
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• v.4 no.1
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• pp.1-56
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• 2022

Why has India become a key actor in the maritime-configured Indo-Pacific region? There are some external factors, but for India, its geo-strategic frontier encompassing its geopolitical and maritime interests is expanding rapidly beyond its territorial space across both the Indian and Pacific oceans amidst an increasingly arduous geopolitical and security environment. India must, therefore, acquire the ability to influence events within this strategic arena using all facets of national power, including maritime-military power. Lately, therefore, New Delhi has invested much intellectual capital to review its maritime-security strategy. India's new strategy is premised on the concept of holistic security involving the 'softer' aspects of maritime-security, and a rekindling of maritime consciousness in India, a nation that has traditionally been beset by 'sea-blindness'. The strategy adopts a region-wide, inclusive, and a more proactive approach than hitherto, as is evident in its title 'Ensuring Secure Seas: Indian Maritime Security Strategy'. While it deals with the growing concern of new non-traditional threats in the Indian littoral and the need for military deterrence and preparedness, it also addresses the imperatives for India to seek a favorable and rules-based benign environment in its immediate and extended maritime periphery, including through multi-vectored strategic partnerships dictated by its enduring principle of strategic autonomy. For a more profound and comprehensive understanding of India's maritime-security strategy, this paper examines the key unstated and implicit factors that underpin the strategy. These include India's historical and cultural evolution as a nation; its strategic geography; its geopolitical and security perceptions; and the political directions to its security forces. The paper deals specifically with India's response to maritime threats ranging from natural disasters, crime and state-sponsored terrorism to those posed by Pakistan and China, as well as the Indian Navy's envisaged security role East of the Malacca Straits. It also analyzes the aspects of organizational restructuring and force planning of India's maritime-security forces.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2011.06a
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• pp.235-235
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• 2011

Lau basin of south Pacific, as an active back arc basin, is promising area bearing seafloor massive hydrothermal deposit that is located in a subduction zone between the Pacific ocean plate and Indo-Australian continental plate. Korea Ocean Research and Development Institute tracked from 2004 to 2006 the hydrothermal activity to the extension of the northeast Lau Basin, targeting seamount. hydrothermal activity by tracking was found hydrothermal evidences. In this study, Marine seismic survey was carried out in the Lau basin seamount of the possibility of hydrothermal deposit. In particular, Marine magnetic survey and seismic survey was carried out at the same time in TA-12 seamount and noise characteristics were found in the seamount. the main process of data processing is Bandpass filter, FK filter, Deconvolution for noise attenuation such backscatter and multiple reflections. the migration is performed to compensate for reflection points followed by seamount of a slope. In this study, bedrock and upper strata could be identified and in the Future, the comparative method with Multi Beam Echo Sounder(MBES) are likely to derive the correct velocity model, the marine magnetic survey results should be considered.

• Korean Journal of Remote Sensing
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• v.33 no.1
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• pp.37-46
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• 2017

Sinabung volcano in Indonesia was formed due to the subduction between the Eurasian and Indo-Australian plates along the Pacific Ring of Fire. After being dormant for about 400 years, Sinabung volcano erupted on the 29th of August, 2010 and most recently on the 1st of November, 2016. We measured the deformation of Sinabung volcano using Advanced Land Observing Satellite/Phased Array type L-band Synthetic Aperture Radar(ALOS/PALSAR) interferometric synthetic aperture radar(InSAR) images acquired from February 2007 to January 2011. Based on multi-temporal InSAR processing, we mapped the ground surface deformation before, during, and after the 2010 eruption with time-series InSAR technique. During the 3 years before the 2010 eruption, the volcano inflated at an average rate of ~1.7 cm/yr with a markedly higher rate of 6.6 cm/yr during the 6 months prior to the 2010 eruption. The inflation was constrained to the top of the volcano. From the 2010 eruption to January 2011,the volcano subsided by approximately 3 cm (~6 cm/yr). We interpreted that the inflation was due to magma accumulation in a shallow reservoir beneath Sinabung. The deflation was attributed to magma withdrawal from the shallow reservoir during the eruption as well as thermo-elastic compaction of erupted material. This result demonstrates once again the utility of InSAR for volcano monitoring.

• Korean Journal of Ichthyology
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• v.35 no.1
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• pp.44-49
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• 2023

A single specimen of the genus Bothus (family Bothidae) was collected for the first time at the intertidal zone of Moseulpo Port, Daejeong-eup, Seogwipo-si, Jejudo Island, on 14 August 2022. The specimen was identified as Bothus pantherinus in having following morphological traits: dark spots and ring-shaped patterns near eyes and the pectoral fins, one distinct spot in the center of the lateral line, 75 lateral line scales, and seven hourglass shaped supracranial pterygiophores. As a result of analyzing 603 bp of mitochondrial DNA COI sequences, our specimen was perfectly matched to those of B. pantherinus registered in NCBI. It has been known that the species is widely distributed throughout the Indo-Pacific Ocean from Red Sea to Hawaiian (32 degrees north to 32 degrees south), but this study revealed that its distribution expanded to the waters of Jejudo Island (33 degrees north), Korea. We propose its new Korean name "Beot-kkoch-mu-nui-dung-geul-neob-chi".

• Maritime Security
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• v.3 no.1
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• pp.141-185
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• 2021

The growing U.S.-China rivalry has placed the countries of Southeast Asia in exceedingly precarious positions. The Republic of Korea (ROK) likewise has been tasked with the challenge of "navigating the waters" between deepening geopolitical divides. It is in this context that the "New Southern Policy" (hereafter NSP) has become a key word in Korea's foreign policy circles. Through NSP, ROK aims to diversify its economic and security interests by strengthening ties with its southern partners, focusing on three key areas (termed as the "3 Ps"): People, Prosperity, and Peace. At the same time, the NSP seeks cooperation with other key diplomatic agendas such as the U.S.'s "Free and Open Indo-Pacific," rendering it crucial for the overall stability of the region. Considering such strategic significance, deeper analysis of the policy is more timely than ever. A brief assessment of the policy's outcome so far, however, reveals that relatively, the "Peace" pillar has been insufficient in achieving satisfactory outcomes. Here, this paper asks the question of: 1) How can the "Peace" pillar of South Korea's New Southern Policy be strengthened? Based on an analysis on the causes of the "Peace" pillar's weakness, this paper identifies counter-piracy cooperation as a solution. This paper then proceeds to answer the next question of: 2) How can ROK and ASEAN cooperate on counter-piracy, and how can these efforts be integrated into ROK's NSP? To answer the above question, this paper conducts in-depth case studies on ASEAN's and ROK's approaches to counter-piracy and identifies specific mechanisms of cooperation. In Chapter I, the paper begins with an overview of the NSP's strategic significance and an evaluation of its "Peace" pillar. Chapter II conducts a literature review on the causes of, and prescriptions for, the weakness of the "Peace" pillar. The paper then justifies why counter-piracy may be a solution. Chapter III examines ASEAN's and ROK's approaches to counter-piracy. By analyzing the general framework and each region's cases, the paper displays the strengths and weaknesses of each region's piracy responses. Based on this analysis, Chapter IV suggests ways to incorporate counter-piracy cooperation into the "Peace" pillar of the NSP. This research bears significance in that it identifies a specific area of cooperation (counter-piracy) to strengthen the "Peace" pillar of ROK's NSP. Such identification is based on a comprehensive study into the two parties' past and current experience in counter-piracy, making it contextual in nature. Furthermore, the study suggests practical mechanisms of cooperation, and considers ways of incorporation into the existing framework of NSP. This approach differs from existing literature that failed to generate case-specific, policy-oriented solutions. The COVID-19 pandemic has exacerbated piracy issues and deepened geopolitical divides. Turbulent seas such as these call for careful navigation. When it comes to promoting "peace," the key lies in combating the pirates that sail those very waters.

• Geophysics and Geophysical Exploration
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• v.11 no.3
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• pp.167-176
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• 2008

Lau basin of the south Pacific, as an active back arc basin, is promising area bearing seafloor massive hydrothermal deposit that is located in a subduction zone between the Pacific ocean plate and Indo-Australian continental plate. We performed multi-beam bathymetry survey in the Lau basin using EM120, to find out high hydrothermal activity Bone. Fonualei Rift and Spreading Center (FRSC) and Mangatolou Triple Junction (MTJ) area were selected for precise site survey through seafloor morphology investigation. The result of surface and deep-tow magnetometer survey showed that Central Anomaly Magnetization High (CAMH) recorded which is associated with active ridge in FRSC-2 and revealed very low magnetic anomalies that can be connected to past or present high hydrothermal activity in MTJ-1 seamount area. Moreover, the physical and chemical tracers of hydrothermal vent flume, i.e., transmission, hydrogen ion concentration (pH), adenosine triphosphate (ATP), methane (CH4) by use of CTD system, showed significant anomalies in those areas. From positive vent flume results, we could conclude that these areas were or are experiencing very active volcanic activities. The acquired chimney and hydrothermal altered bed rock samples gave us confidence of the existence of massive hydrothermal deposit. Even though not to use visual exploration equipment such as ROV, DTSSS, etc., traditional marine geophysical investigation approach might be a truly cost-effective tool for exploring seafloor hydrothermal massive deposit.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2605-2610
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• 2016

The International Myeloma Working Group considers the serum free light chain (SFLC) assay to be an adjunct to traditional tests. Apart from the FLC ratio, the absolute values of individual free light chains also are gaining importance as they appear to be more relevant in certain clinical settings. Automated assays are available for their determination. As laboratories put new test systems into use catering to different disease populations, they are required by accreditation and certification bodies to verify or establish performance specifications, including reference intervals (RIs) representative of their population. Our aim was to establish local RIs for SFLC in a multicentre representative healthy population using a robust method. There was no significant relationship between SFLC levels and age, gender and creatinine levels. The 95% RI for ${\kappa}SFLC$ was 4.81 to 33.86mg/L, for ${\lambda}$ SFLC was 5.19 to 23.67mg/L and for ${\kappa}/{\lambda}SFLC$ was 0.36 to 2.33, significantly higher than the values given by the manufacturer. The ${\kappa}/{\lambda}$ SFLC ratio at 2.23, covering 100% of the data, showed 72% sensitivity (95% CI=39.0 - 94.0), 100% specificity (95% CI=71.5 - 100.0), 100% PPV (95% CI=21.5 - 100.0), 95% NPV (95% CI=75.4 - 99.9), and 79% accuracy (95% CI=56.0 - 93.0). In the patient group, kit RI for ${\kappa}/{\lambda}$ SFLC ratio classified 45.5% (n=5) as positive vs 9.1% (n=1) positive by the study RI, while the kit RI for kappa FLC classified 90.9% (n=10) as positive vs 54.5% (n=6), indicating increased probability of false positive test results with the kit RI when applied to our patient population. Appropriate and specific reference intervals and criteria values result in fewer false-positive and false-negative results which means fewer wrong or missed diagnoses.

• Analyses & Alternatives
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• v.6 no.1
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• pp.69-114
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• 2022

This paper analyzes Taiwan's 「New Southbound Policy」 from the perspective of 'balancing' and 'bandwagoning' in international politics. Specifically, it examines the changes and characteristics of 'Southbound policies' that have continued since the period of the Lee Teng-hui(李登輝) administration, and examines the meaning of the New Southbound Policy promoted by the Tsai Ing-wen(蔡英文) administration. Taiwan's foreign policy has been strongly influenced by external variables such as U.S.-China relations. Previous Taiwanese governments have actively promoted Southbound policies to advance to Southeast Asian countries such as ASEAN with the aim of 'De-Sinicization', but have not achieved much results. This is because variables such as cooperative U.S.-China relations and strong checks from China played a role at the time. In this environment, Taiwan had to pursue an appropriate 'balancing' between the United States, China, and Southeast Asian countries. However, since the inauguration of the Trump administration, strategic competition between the U.S. and China has been maximized, creating a new space for Taiwan's foreign policy. This is because the U.S. valued cooperation with Taiwan in the process of embodying the 'Indo-Pacific Strategy' to curb China's rise. The New Southbound Policy promoted by the Tsai Ing-won administration is different from the existing Southbound policies in that it seeks to link with the U.S. India-Pacific Strategy and attempts to advance to South Asian countries such as India. From an international political point of view, the Tsai Ing-won administration's New Southbound Policy can be interpreted as a 'bandwagoning' to the United States, not a balanced strategy between the U.S. and China. Strategic competition between the U.S. and China is expected to intensify for a considerable period of time in the future, and honeymoon between Taiwan and the U.S. are also expected to continue. Taiwan's bandwagoning strategy, which actively pursues a link between the New Southbound Policy and the India-Pacific Strategy, is also expected to be maintained.