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A Systematic Review of Economic Analysis on Idiopathic Short Stature (특발성 저신장의 경제성 평가 연구 경향 분석: 체계적 문헌고찰)

  • Lee, Boram;Kwon, Chan-Young;Jang, Soobin
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.2
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    • pp.1-10
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    • 2021
  • Objectives We aimed to examine health-related economic analysis of available interventions on idiopathic short stature (ISS). Methods Eight studies were reviewed from English, Korean, and Chinese databases which were published up to December 24, 2020. Effectiveness, utility, and cost data were extracted from the studies and descriptive analysis of the individual studies was conducted Results Five studies were chosen. In the two economic evaluation studies, the incremental cost-effectiveness ratio (ICER) of growth hormone (GH) treatment was presented by performing cost-effectiveness analysis based on the deterministic decision tree approach for the GH and untreated group. Final adult height and direct medical costs were analyzed as effectiveness and cost outcomes. In 1 review article, an ICER of GH was presented based on systematic review on the effects of the GH treatment. In the two clinical trials, the effectiveness and cost of the 12 months Oriental medicine combination treatment were presented in comparison with the GH treatment alone. There were no literatures that provided utility data of available intervention on ISS. Conclusions The results of this study will be used as basic data for the economic analysis of Oriental medicine treatment on ISS in the future.

New record of an alien plant, Desmodium paniculatum (Fabaceae), in Korea based on a morphological examination and DNA barcoding (형태와 DNA 바코드에 근거한 한국 미기록 외래식물의 보고, 미국잔디갈고리(콩과))

  • JIN, Dong-Pil;KIM, Jung-Hyun;SIM, Sunhee;SUH, Hwa-Jung;KIM, Jin-Seok
    • Korean Journal of Plant Taxonomy
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    • v.51 no.2
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    • pp.133-140
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    • 2021
  • Desmodium paniculatum (Fabaceae), native to North America and an alien plant in Japan, was newly found in Hwaseong-si and Daejeon-si, Korea. This species is distinguished from Korean-related taxa based on certain morphological features. Specifically, it is a perennial herb, with a 4-5 jointed loment, and with the basal suture moderately incised between the articles. In the field, D. paniculatum grows around rivers and roadsides, suggesting that it is likely to have been introduced through river improvement work and road construction. On the phylogenetic tree based on an internal transcribed spacer, Korean individuals forms a clade with a Japanese individual. Here, we report a morphological description, photographs, an illustration, and the locality of D. paniculatum.

Natural Regeneration Potential of the Soil Seed Bank of Land Use Types in Ecosystems of Ogun River Watershed

  • Asinwa, Israel Olatunji;Olajuyigbe, Samuel Olalekan
    • Journal of Forest and Environmental Science
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    • v.38 no.3
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    • pp.141-151
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    • 2022
  • Soil seed banks as natural storage of plant seeds play an important role in the maintenance and regeneration of watershed. Natural regeneration potential of the soil seed bank of Land use types (LUTs) in Ogun River watershed (ORW) was investigated. ORW was stratified using proportionate sampling technique into Guinea Savannah (GS), Rainforest (RF) and Swamp Forest (SF) Ecological Zones (EZs). Three LUTs: Natural Forest (NF), Disturbed Forest (DF) and Farmland (FL) were purposively selected in GS: GSNF, GSDF, GSFL; RF: RFNF, RFDF, RFFL and SF: SFNF, SFDF, SFFL, respectively. Systematic line transects was used in the laying of the sample plots. Sample plots of 25 m×25 m were established in alternate positions. Ten 1 m×1 m quadrats were randomly laid for soil core sampling from previously randomly selected ten plots. The core samples (10) were pooled per plot in each LUT and placed in individual trays. Ten trays with sterilized soil were used as control. The trays were watered regularly and checked for seedlings emergence fortnightly for 18 months. The experimental design used was 3×3 factorial experiments. ANOVA, Diversity index (H') and Similarity index (SI) were used to analyze the data. There was significant difference in seedling emergence among ecological zones and land use types (p<0.05). A total of 4,400 seedlings emerged from the soil samples. All species were distributed among 32 families. FL in the RF had the highest number of germinated seeds (705±37.33 seedlings) followed by DF in the RF (701±49.6 seedlings). The lowest emergence was in NF of the SF (199±28.41 seedlings). DF in the RF had highest number of species (34) distributed among 22 families. Emergence from soil seed bank of NF in ORW was generally with more of tree species than herbs that were predominant in FL and DF.

Vacant House Prediction and Important Features Exploration through Artificial Intelligence: In Case of Gunsan (인공지능 기반 빈집 추정 및 주요 특성 분석)

  • Lim, Gyoo Gun;Noh, Jong Hwa;Lee, Hyun Tae;Ahn, Jae Ik
    • Journal of Information Technology Services
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    • v.21 no.3
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    • pp.63-72
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    • 2022
  • The extinction crisis of local cities, caused by a population density increase phenomenon in capital regions, directly causes the increase of vacant houses in local cities. According to population and housing census, Gunsan-si has continuously shown increasing trend of vacant houses during 2015 to 2019. In particular, since Gunsan-si is the city which suffers from doughnut effect and industrial decline, problems regrading to vacant house seems to exacerbate. This study aims to provide a foundation of a system which can predict and deal with the building that has high risk of becoming vacant house through implementing a data driven vacant house prediction machine learning model. Methodologically, this study analyzes three types of machine learning model by differing the data components. First model is trained based on building register, individual declared land value, house price and socioeconomic data and second model is trained with the same data as first model but with additional POI(Point of Interest) data. Finally, third model is trained with same data as the second model but with excluding water usage and electricity usage data. As a result, second model shows the best performance based on F1-score. Random Forest, Gradient Boosting Machine, XGBoost and LightGBM which are tree ensemble series, show the best performance as a whole. Additionally, the complexity of the model can be reduced through eliminating independent variables that have correlation coefficient between the variables and vacant house status lower than the 0.1 based on absolute value. Finally, this study suggests XGBoost and LightGBM based machine learning model, which can handle missing values, as final vacant house prediction model.

Genome-wide identification and expression profiling of the pectin methylesterase gene family in Citrus sinensis (L.) Osbeck

  • Ho Bang Kim;Chang Jae Oh;Nam-Hoon Kim;Cheol Woo Choi;Minju Kim;Sukman Park;Seong Beom Jin;Su-Hyun Yun;Kwan Jeong Song
    • Journal of Plant Biotechnology
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    • v.49 no.4
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    • pp.271-291
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    • 2022
  • Pectin methylesterase (PME) plays an important role in vegetative and reproductive development and biotic/abiotic stress responses by regulating the degree of methyl-esterification of pectic polysaccharides in the plant cell wall. PMEs are encoded by a large multigene family in higher land plant genomes. In general, the expression of plant PME genes shows tissue- or cell-specific patterns and is induced by endogenous and exogenous stimuli. In this study, we identified PME multigene family members (CsPMEs) from the sweet orange genome and report detailed molecular characterization and expression profiling in different citrus tissues and two fruit developmental stages. We also discussed the possible functional roles of some CsPME genes by comparing them with the known functions of PMEs from other plant species. We identified 48 CsPME genes from the citrus genome. A phylogenetic tree analysis revealed that the identified CsPMEs were divided into two groups/types. Some CsPMEs showed very close phylogenetic relationships with the PMEs whose functions were formerly addressed in Arabidopsis, tomato, and maize. Expression profiling showed that some CsPME genes are highly or specifically expressed in the leaf, root, flower, or fruit. Based on the phylogenetic relationships and gene expression profiling results, we suggest that some CsPMEs could play functional roles in pollen development, pollen tube growth, cross incompatibility, root development, embryo/seed development, stomata movement, and biotic/abiotic stress responses. Our results shed light on the biological roles of individual CsPME isoforms and contribute to the search for genetic variations in citrus genetic resources.

The Variation of Natural Population of Pinus densiflora S. et Z. in Korea(II) -Characteristics of Needle and Wood of Myong-Ju, Ul-Jin, and Suweon Populations- (소나무천연집단(天然集團)의 변이(變異)에 관(關)한 연구(硏究)(II) -명주(溟州), 울진(蔚珍), 수원집단(水原集團)의 침엽(針葉) 및 재질형질(材質形質)-)

  • Yim, Kyong Bin;Kwon, Ki Won
    • Journal of Korean Society of Forest Science
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    • v.31 no.1
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    • pp.8-20
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    • 1976
  • For study on the variation of natural stand, three populations of Pinus densiflora S. et Z. were selected at samsanri Yongogmyun Myongjugun Kangwondo (4), Hawonri seomyun Uljingun Kyongbuk (5), and Emogdong Suweon Kyongkido (6) successibely after the selection of three population in 1974. Twenty individual trees were chosen from each population and the morphological characteristics of trees, needle and wood properties were investigated on the trees. The results are summerized as follows; 1. Serration density, resin canal number in needle did not show significant differences, however stomata row number in the both sides of needle showed highly significant differences among 3 populations. But significant differences were calculated among individual trees in a population regarding any character of needles. 2. Ail population had high correlation on the stomata row between abaxial and adaxial side of needle. 3. The Myongjungun population showed the highest value of resin duct index, which means the population had the highest degree of hybrid character. 4. The ring segment width and summerwood percentage in the wood properties had significant differences, and yet specific gravity and tracheid length had not significant differences statistically among 3 populations. But all the values were significant statistically among the ring segments within population. 5. The ring segment width decreased rapidly with increasing tree age but summerwood percentage, specific gravity, tracheid length increased slowly to the middle age of tree and then decreased slowly after the age. But the patterns of decrease or increase were some different by population. 6. The values of Uljingun population were generally high in the coefficient of variation on all the needle characters. And the values of Suweon population were always the highest and those of Myongjugun population the lowest in the coefficient of variation on all the wood properties.

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Estimation of Heritabilities and Genetic Gains for Height and Diameter Growth of Korean White Pine Open-Pollinated Progeny Stands (잣나무 풍매차대검정림(風媒次代檢定林)의 수고(樹高) 및 직경생장(直徑生長)의 유전력(遺傳力)과 개량효과(改良效果)에 관한 연구(硏究))

  • Chon, Sang-Keun;Shin, Man Yong;Chung, Dong-Jun;Jang, Yong-Seok
    • Journal of Korean Society of Forest Science
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    • v.90 no.1
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    • pp.105-112
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    • 2001
  • This study was carried out to analyze the genetic variation and to estimate both heritabilities and genetic gains for height and diameter growth of 20-year-old open-pollinated progenies of Korean white pine in three different sites. For there, analysis of variance for both height and diameter growth was conducted to see if there exist significant differences among families, sites, blocks, and their interactions exist or not and to analyze the variance components for each factor. Mean height and diameter at Gapyeong site were 7.65m and 11.92cm, respectively. they were 7.42m and 11.35cm at Gwangiu site, 6.13m and 8.41cm at Youngdong site, and 7.12m and 10.68cm for the overall sites. The family No. 20 showed the most excellent growth of 7.99m in mean height and 12.14cm in mean diameter for all sites surveyed. The estimates of heritabilities for individual-tree and family were, 0.35~0.73 and 0.65~0.83 for height growth, and 0.12~0.40 and 0.46~0.75 for diameter growth, respectively. For the combined data from all the sites, the estimates of individual tree heritability were 0.60 for height and 0.20 for diameter, and those of family were 0.91 for height and 0.77 for diameter. Heritability estimates varied with testing sites, and those for height were higher than those for diameter in all sites. Given equal intensity of selection, combined selection method provided the most efficient genetic gains for both height and diameter growth.

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Estimation of Productivity for Quercus variabilis Stand by Forest Environmental Factors (삼림환경인자(森林環境因子)에 의한 굴참나무임분(林分)의 생산력추정(生産力推定))

  • Lee, Dong Sup;Chung, Young Gwan
    • Journal of Korean Society of Forest Science
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    • v.75 no.1
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    • pp.1-18
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    • 1986
  • This study was initiated to estimate productivity of Quercus variabilis stand. However the practical objective of this study was to provide some information to establish the basis of selecting the suitable site for Quercus variabilis. The productivity measured in terms of DBH, height, basal area and stem volume was hypothesized, respectively, to be a function of a group of factors. This study considered 32 factors, 20 of which were related to the forest environmental factors such as tree age, latitude, percent slope, etc. and the rest of which were related to soil factors such as soil moisture, total nitrogen, available $P_2O_5$, etc. The data on 4 productivity measurements of Quercus variabilis growth and related factors cited were collected from 99 sample plots in Kyeongbook and chungbook provinces. Some factors considered were, in nature, discrete variables and the others continuous variables. Each kind of factor was classified into 3 or 4 categories and total numbers of such categories were eventually amounted to 110. Then each category was treated as an independent variable. This is amounted to saying that individual variable was treated a dummy variable and assigned a value 1 or 0. However the first category of each factor was deleted from the normal equation for statistical consideration. First of all, each of 4 productivity measurements of Quercus variabilis growth was regressed and, at the same time, those 110 categories. Secondly, the partial correlation coefficients were measured between each pair of 4 productivity measurements and 32 individual foctors. Finally, the relative scores were estimated in order to derive the category ranges. The result of these statistical analyses could be summarized as follows: 1) Growth measurement in terms of height seems to be a more significant criterion for estimation of productivity of Quercus variabilis. 2) Productivity of forest on stocked land may better be estimated in terms of forest environmental factors, on the other hand, that of unstocked land may be estimated in terms of physio-chemical factors of soil. 3) The factors that a strongly positive relation to all growth factors of tree are age group, effective soil, soil moisture, etc. This implies that these factors might effectively be used for criteria for selecting the suitable site for Quercus variabilis. 4) Parent rock, latitude, total nitrogen, age group, effective soil depth, soil moisture, organic matter, etc., had more significant category range for tree growth. Therefore, the suitable site for Quercus variabilis may be selected, based on this information. In conclusion, the above results obtained by the multivariable analysis can be not only the important criteria for estimating the growth of Quercus variabilis but also the useful guidance for selecting the suitable sites and performing the rational of Quercus variabilis forest.

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Effect of Air Pollution on Cherry Tree (Prunus yedoensis Matsumara) Planted on National Roadsides between Cheonju and Kunsan City(II) - Chlorophyll, Magnesium and Sodium Contents in the Leaves - (대기오염(大氣汚染)이 전주(全州)-군산간(群山間) 국도변(國道邊) 왕벚나무에 미치는 영향(影響)(II) - Chlorophyll, Mg 및 Na 함유량(含有量)을 중심으로 -)

  • Hwang, Yu Chul;Kim, Chang Ho;Yim, Kyong Bin
    • Journal of Korean Society of Forest Science
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    • v.81 no.3
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    • pp.224-233
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    • 1992
  • This report succeds the previous paper, the source of materials and statistical designs used were not altered. Under the hypothesis of maleffect of atmospheric pollutions emitted mainly by traffic automobiles on 20-year-old, Prunus yedoensis roadside trees planted along national road between Cheonju abd Kunsan, chlorophyll a and b contents, magnesium and sodium contents of leaves were analysed on September 15. Besides control sites considered to be a pollution free district, 20 polluted road-side sites, 10 on left roadside and 10 on right roadside, oppositely faced in pairs were selected. The leaves collected from 5 trees at each sampling site were bulked to eliminate the individual tree variation. Chlorophyll were extracted by Mackinney and Arnon method. The results obtained are as follows : 1. The planting belt width between road shoulder and paved road face edge for cherry trees, 160~170cm, was considered too narrow for the growing space. 2. On an average, the total chlorophyll content between Cheonju and Iri($8.60{\sim}9.31ml/cm^2$) was lower than that for between Iri and Kunsan($9.24{\sim}10.74ml/cm^2$). 3. The chlorophyll b content showed the difference, higher on right roadside and lower on left side. However this difference could be confirmed by matched pair T-test at 10% level. 4. Without exception, the chlorophyll contents of control sites were higher than those of road-side trees, implying the maleffect of atmospheric pollutants on cherry tree growth. 5. On the contrary, magnesium and sodium contents of the leaves of road-side trees were higher than that of control site trees.

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Trends in Genetic Parameters with Age and Site for Early Implications of Genetic Improvement in Korean White Pine (잣나무의 유전적(遺傳的) 형질(形質) 개량(改良)의 조기검정(早期檢定)을 위한 수령(樹齡) 및 입지별(立地別) 생장(生長)과 유전모수(遺傳母數)의 특성(特性)에 관(關)한 연구(硏究))

  • Kim, Dae Eun;Chon, Sang Keun
    • Journal of Korean Society of Forest Science
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    • v.79 no.1
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    • pp.56-70
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    • 1990
  • Eighteen Korean white pine (P. koraiensis S. et Z.) families were tested in 3 different regions from age 5 to 9. Family and site were significant sources of variation for seedling survival and field growth, whereas the effects of family x site interaction ware relatively small as compared with the former sources of variation. Variance components estimated from the separate and combined sites indicated that the most variabilities were associated with individual trees within plot. Family ${\times}$ site interaction components as a percentage of family variance decreased sharply with age. Heritability estimates varied with testing site and tree age. Combined analyses, however, showed a moderate change in heritability with increasing tree ages, and demonstrated high and stable trends of estimates, particularly in family heritabilities of tree height ($h_F{^2}=0.789-0.798$). The gains estimated from combined analysis have expected maximum or near-maximum efficiencies at age 6 or 7. Given equal intensity of selection, mass selection showed the most efficient gains within and across the sites. However, for the differences between mass and combined selections are small, selection made on the combination of family and within-family would be more effective in improving genetic gains. Indirect selection method indicated that 5-and 6-years height were all good predictors of 9-year-old height with little loss of relative efficiency (less than 10%) as compared with direct family selection at age 9. Phenotypic and genetic correlations computed on the basis of family mean values of height and diameter have shown predominantly high, positive, and statistically significant (1% level) relationships between all tested pairs of traits, which indicates that family growth maintained statistically consistent trends with age. The best families are those that maintained a stable superiority overall sites and ages in growth performance, therefore, it can be suggested that early identification of superior families at age 9 is feasible at age 5 or 6 in Pinus koraiensis S. et Z.

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