• Title/Summary/Keyword: Individual Risk Model

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The Risk of Breast Cancer in Women in Their 40s by Economic Activity (경제활동에 따른 40대 여성의 유방암 발생 위험도)

  • Choi, Hyang-Ha;Seo, Hwa-Jeong
    • Journal of radiological science and technology
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    • v.43 no.1
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    • pp.23-27
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    • 2020
  • In South Korea, female individuals in their forties show a high rate of incidence, with approximately 13% of the patients being <40 years. This statistic is more than twice as high as that in Western countries. It is therefore necessary to identify the risk factors for breast cancer incidence by age and economic activity participation status. Women aged 30 to 59-whether breast cancer patients or those in the control group and having no breast cancer-were appraised from the sample cohort database. The data were analyzed using the statistical software R36.2. To identify the factors affecting breast cancer incidence, the degree of association was determined with HR and 95% CI by means of cox regression analysis. As for the socio-demographic variables, the older the individual, the higher the risk of breast cancer incidence becomes. As for the economic activity variables, those who were dependents (unemployed) and who had higher income (medium and high) were at higher risk of breast cancer incidence, which was statistically significant. The income-adjusted HR (model 1) for breast cancer development associated with the economic activity was 1.452 (95% CI, 1.19-1.77). The body mass index and alcohol intake-adjusted HR (model 2) was 1.431 (95% CI, 1.18-1.74). One needs to pay attention to policy plans regarding women's quality of life, as well as to the risk of breast cancer incidence by their economic activity. In other words, policies need to give post care, instead of focus on early detection and cancer treatment.

Internal and External Characteristics of Information Security Officers Affecting Organization's Information Security Performance (조직 정보보호성과에 영향을 미치는 정보보호담당임원의 내·외적 특성)

  • Oh, Ha-Kyeong;Kim, Tae-Sung
    • Journal of Information Technology Applications and Management
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    • v.27 no.4
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    • pp.1-19
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    • 2020
  • Infringement of information security has caused the corporate image to be damaged and share price to fall, and it is emerging as an organizational risk. The value of information assets in enterprises has led to a higher level of security than in the past. As a result, companies are aware of the need for officers to protect information and to oversee a security management system. However, despite the growing importance of information security officers, there is a lack of research on their roles and characteristics. This study validates the relationship between determinants that affect the performance of information security. And a structural equation model was presented and empirically analyzed to see the impact of the internal and external characteristics of the staff in charge of information security on the organization's information security performance.

The Effect of Ambiguity Aversion on Self-Protection and Self-Insurance effort (모호성 회피성향이 손실 발생 확률 및 손실 크기를 줄이기 위한 노력에 미치는 영향)

  • Hong, Ji-Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.4
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    • pp.433-438
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    • 2018
  • This study examined the effects of ambiguity aversion on the self-protection and self-insurance efforts using a two-period model to consider the time difference between making an effort and occurring loss, which is in contrast with the existing one-period model. The loss follows a binary distribution while the distribution is ambiguous. The distribution depends on the state variable. First, the effort of ambiguity averse individuals is not always greater than that of ambiguity neutral ones. Second, the effects of absolute ambiguity aversion (AAA), which does not appear in one-period model, were observed. Not-increasing AAA is a sufficient condition to increase the efforts of ambiguity averse individuals compared to those of ambiguity neutral ones. In addition, the change in effort also depends on the probability function of the state. Lastly, the results hold even when the individual is risk neutral or risk loving. As a result, ambiguity aversion needs to be considered independently with risk aversion.

Helicobacter pylori and Pancreatic Cancer Risk: a Meta-analysis Based on 2,049 Cases and 2,861 Controls

  • Wang, Yin;Zhang, Fu-Cheng;Wang, Yao-Jun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4449-4454
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    • 2014
  • Aim: Helicobacter pylori (H. pylori) have been considered as a risk factor for many cancers. We conducted this meta-analysis to clarify the association between H. pylori infection and the risk of pancreatic cancer. Methods: We searched the Medicine/Pubmed and Embase databases, studies about the association between H. pylori infection and pancreatic cancer published up to Jan.2014 were included. Finally, a total of 9 studies were used for this a meta-analysis. The odds ratios (ORs) and 95% confidence interval (95%CI) of H. pylori infection on pancreatic cancer with respect to control groups were evaluated. Two authors independently assessed the methodological quality and extracted data. This meta-analysis was conducted using software, state (version 12.0) to investigate heterogeneity among individual studies and to summarize the studies. Using the fixed-effects or random-effects model, depending on the absence or presence of significant heterogeneity. Sensitivity analysis was performed to assess the influence of each individual study on the pooled ORs by omitting a single study each time. Publication bias was evaluated by funnel plot, using Egger's and Begg's tests. Results: There was no significant association between H. pylori infection and pancreatic cancer risk in the summary ORs,(OR=1.06, 95%CI: 0.74-1.37) through the random-effect method, but heterogeneity among studies was significant ($I^2$=58.9%), so we put the studies into two subgraphs (eastern and western). The results about western (OR=1.14 95%CI:0.89, 1.40) showed heterogeneity among the western countries of $I^2$=6.6%, with no significant association between Hp+ and pancreatic cancer, but the eastern countries (OR=0.62, 95%CI:0.49, 0.76), $I^2$=0, suggested that decreasing pancreas-cancer risk in subjects with Hp+ infection. Simultaneously, 7 studies examined CagA+ strains was (OR=0.84 95%CI:0.63, 1.04), $I^2$=36% with the random-effect method, subgraphs indicated that CagA+ could decrease the risk of pancreatic cancer in the eastern subjects (OR=0.66, 95%CI:0.52-0.80), but the association was not statistically significant in the western subjects (OR=0.95, 95%CI:0.73, 1.16). Conclusion: Hp+ and CagA+ infection are associated with a decreased risk of pancreatic cancer in eastern populations but have no significant associations in western countries.

An analysis of determinants of purchase intension of individual pension using structural equation model (구조방정식모형을 이용한 개인연금 가입의향의 결정요인 분석)

  • Lee, Chanhee;Jung, Hongjoo
    • The Korean Journal of Applied Statistics
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    • v.29 no.3
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    • pp.409-424
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    • 2016
  • This study analyzed the causal relationship among factors that influence the purchase intensions for individual pensions which have a growing importance as a financial means after retirement. For this purpose, structural equation modeling based on the survey data (N = 928) was conducted to analyze psychological factors and financial factors comprehensively. According to empirical results of the structural equation, in the case of non-subscribers of individual pensions, potential longevity and coping efficacy influenced the purchase intensions for individual pensions fully mediated by fear and worry about longevity. Trust in insurers and risk tolerance directly influenced the purchase intensions for individual pensions. These show that trust in insurers is the most important factor in purchase intensions for individual pensions. Also, only trust in insurers give a direct impact on individual pensions in the case of individual pension subscribers. Longevity-related emotional side is expected to help in marketing activities that target potential customers signing individual pensions. In addition, trust in insurers has the greatest impact on new and additional subscriptions that represent critical efforts to improve trust in insurers.

Statistical models and computational tools for predicting complex traits and diseases

  • Chung, Wonil
    • Genomics & Informatics
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    • v.19 no.4
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    • pp.36.1-36.11
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    • 2021
  • Predicting individual traits and diseases from genetic variants is critical to fulfilling the promise of personalized medicine. The genetic variants from genome-wide association studies (GWAS), including variants well below GWAS significance, can be aggregated into highly significant predictions across a wide range of complex traits and diseases. The recent arrival of large-sample public biobanks enables highly accurate polygenic predictions based on genetic variants across the whole genome. Various statistical methodologies and diverse computational tools have been introduced and developed to computed the polygenic risk score (PRS) more accurately. However, many researchers utilize PRS tools without a thorough understanding of the underlying model and how to specify the parameters for the best performance. It is advantageous to study the statistical models implemented in computational tools for PRS estimation and the formulas of parameters to be specified. Here, we review a variety of recent statistical methodologies and computational tools for PRS computation.

Application to the Stochastic Modelling of Risk Measurement in Bunker Price and Foreign Exchange Rate on the Maritime Industry (확률변동성 모형을 적용한 해운산업의 벙커가격과 환율 리스크 추정)

  • Kim, Hyunsok
    • Journal of Korea Port Economic Association
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    • v.34 no.1
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    • pp.99-110
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    • 2018
  • This study empirically examines simple methodology to quantify the risk resulted from the uncertainty of bunker price and foreign exchange rate, which cause main resources of the cost in shipping industry during the periods between $1^{st}$ of January 2010 and $31^{st}$ of January 2018. To shed light on the risk measurement in cash flows we tested GBM(Geometric Brownian Motion) frameworks such as the model with conditional heteroskedasticity and jump diffusion process. The main contribution based on empirical results are summarized as following three: first, the risk analysis, which is dependent on a single variable such as freight yield, is extended to analyze the effects of multiple factors such as bunker price and exchange rate return volatility. Second, at the individual firm level, the need for risk management in bunker price and exchange rate is presented as cash flow. Finally, based on the scale of the risk presented by the analysis results, the shipping companies are required that there is a need to consider what is appropriate as a means of risk management.

Citrus Fruits Intake and Prostate Cancer Risk: A Quantitative Systematic Review

  • Bae, Jong-Myon;Lee, Eun-Ja;Guyatt, Gordon
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.3
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    • pp.159-164
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    • 2008
  • Objectives : The purpose of this systematic review was to investigate the association between dietary intake of citrus fruits and prostate cancer risk. Methods : Authors searched electronic databases and the reference lists of publications of diet and prostate cancer studies until August 2007. All of the epidemiological studies that obtained individual data on dietary intake of citrus fruits and presented risk estimates of the association between intake of citrus fruits and risk of prostate cancer were identified and included. Using general variance-based methods, study-specific odds ratios (OR)/ relative risk (RR) and associated confidence interval (CI)/ standard error (SE) for highest versus lowest intake of citrus fruits level were extracted from each paper. Results : Eleven articles including six case-control studies, one nested case-control study and four cohort studies, proved eligible. Overall summary OR using random effect model did not show an association in risk of prostate caner with intake of citrus fruits (summary OR=1.03, 95% CI=0.89-1.19) with large heterogeneity across studies that we were unable to explain ($I^2$=67.88%). The summary ORs in case-control studies and cohort studies were 1.10 (95% CI=0.97-1.22) and 1.05 (95% CI=0.96-1.14), respectively. Conclusions : Pooled results from observational studies did not show an association between intake of citrus fruits and the risk of prostate cancer, although results vary substantially across studies.

A Case Study on Product Production Process Optimization using Big Data Analysis: Focusing on the Quality Management of LCD Production (빅데이터 분석 적용을 통한 공정 최적화 사례연구: LCD 공정 품질분석을 중심으로)

  • Park, Jong Tae;Lee, Sang Kon
    • Journal of Information Technology Services
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    • v.21 no.2
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    • pp.97-107
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    • 2022
  • Recently, interest in smart factories is increasing. Investments to improve intelligence/automation are also being made continuously in manufacturing plants. Facility automation based on sensor data collection is now essential. In addition, we are operating our factories based on data generated in all areas of production, including production management, facility operation, and quality management, and an integrated standard information system. When producing LCD polarizer products, it is most important to link trace information between data generated by individual production processes. All systems involved in production must ensure that there is no data loss and data integrity is ensured. The large-capacity data collected from individual systems is composed of key values linked to each other. A real-time quality analysis processing system based on connected integrated system data is required. In this study, large-capacity data collection, storage, integration and loss prevention methods were presented for optimization of LCD polarizer production. The identification Risk model of inspection products can be added, and the applicable product model is designed to be continuously expanded. A quality inspection and analysis system that maximizes the yield rate was designed by using the final inspection image of the product using big data technology. In the case of products that are predefined as analysable products, it is designed to be verified with the big data knn analysis model, and individual analysis results are continuously applied to the actual production site to operate in a virtuous cycle structure. Production Optimization was performed by applying it to the currently produced LCD polarizer production line.

Factors Influencing the Preference for German farm Tourism: A Path Model Approach

  • Sidali, Katia Laura;Spiller, A.
    • Journal of Global Scholars of Marketing Science
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    • v.18 no.4
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    • pp.33-59
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    • 2008
  • This paper aims to analyse the preference for German farm tourism among the German population. For this reason, we conducted an empirical study in Germany during summer 2007 and we applieda structural equation model based on partial leasts quares(PLS) to analyse the data. In the following chapters we will introduce the literature review and our conceptual frame work. We will then outline the procedures we adopted and the results of the empirical analysis. In the final part so me conclusions will be presented and a discussion will follow in order to draw the future directions of our research. According to our hypotheses, the possibility that agri-tourism enters in the evoked set of an individual is higher: H1: The higher the information degree about it. H2: The lower the influence of the social stimuli. H3: The higher the physical exposure to it (experience). H4: The higher the wellness image of agri-tourism. H5: The higher the traditional image of agri-tourism. H6: The higher the exciting image of agri-tourism. H7: The higher the perceived value for money. Our further hypotheses affirm that the possibility that agri-tourism enters in the evoked set of an individual is higher: H8: The lower the perceived risk. H9: The higher the motive to enjoy a holiday in the nature. H10: The higher the motive to enjoy a sport holiday. H11: The lower the motive to have an organized holiday. H12: The lower the motive to have a holiday abroad. H13: The lower the motive of action and night life. H14: The higher the motive to spend a holiday with the family. H15: The lower the motive to spend a city holiday. Finally, our model has some socio-demographics data. As we mentioned before, German agri-tourism has traditionally been the travel destination of large-size families, with low-to-middle income. For that reason, our final hypothesises are the following: the possibility that agri-tourism enters in the evoked-set of an individual is higher: H16: The higher the number of family members. H17: The lower the family income. Since in this study we use a path model with a PLS approach, we are able to state some interrelations among the exogenous latent variables: H18: The motive of sport holiday has a positive influence towards nature motives. H19: The physical exposition to agri-tourism has a positive influence toward information. H20: The motive of family holiday has a negative influence toward the motive of action and night life. H21: Social stimuli have a positive influence towards individuals risk perceptions. H22: Social stimuli have negative influence towards experience. Data for this study were gathered via administrated questionnaires during the summer 2007 within the frame of an academic "marketing research" course. The corresponding t-values are assessed using the bootstrapping method with 500 re-samples. In our model 61% of the degree of appreciation of German agri-tourism (evoked set) is explained by five independent variables: value for money ($0.335^{{\ast}{\ast}{\ast}}$) (H7) experience ($0.267^{{\ast}{\ast}}$) (H3), exciting image ($0.204^{\ast}$) (H6) organisation ($-0.162^{\ast}$) (H11) and holiday abroad ($-0.156^{\ast}$) (H12). The variance explained ($R^2$) for the other endogenous variables are the following: nature 24.3%, information 14.1%, action holiday 13.8%, risk perception 5.8% and experience 2.4%. An overview can be inferred from table 5. The results also allow us to test each of the proposed hypotheses. With exception of organization and abroad, none of the others travel style factors (H9 to H15) seem to have any significant impact towards evoked set which leads to the rejection of the respective hypotheses. As expected, social stimuli have a significant influence on individuals' risk perception (H21 accepted), however neither the former nor the latter have a valuable impact on evoked set (rejection of H2 and H8). Besides, since the influence of social stimuli towards experience is not significant, also H22 has to be rejected. Experience influences information (H19 accepted) but the latter does not affect significantly the evoked set (H1 rejected). Both H4 as well as H5, referring respectively to the perceived images of German agri-tourism as a wellness destination and the traditional image of the German farm tourism have to be rejected. Finally, none of the demographic data included in the model explains significantly the variance of the factor evoked set. Therefore neither H16 nor H17 has been accepted. As far as the interrelation between sport and nature (H18) and family and action (H20) are concerned, the stated relationship among these variables has been statistically confirmed. Our path model based on partial least squares shows the factors influencing the preference for farm tourism in Germany. Among others value for money and experience are the most significant ones. Practical implications are discussed.

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