• Title/Summary/Keyword: Inclusion-complex

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Structural system reliability-based design optimization considering fatigue limit state

  • Nophi Ian D. Biton;Young-Joo Lee
    • Smart Structures and Systems
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    • v.33 no.3
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    • pp.177-188
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    • 2024
  • The fatigue-induced sequential failure of a structure having structural redundancy requires system-level analysis to account for stress redistribution. System reliability-based design optimization (SRBDO) for preventing fatigue-initiated structural failure is numerically costly owing to the inclusion of probabilistic constraints. This study incorporates the Branch-and-Bound method employing system reliability Bounds (termed the B3 method), a failure-path structural system reliability analysis approach, with a metaheuristic optimization algorithm, namely grey wolf optimization (GWO), to obtain the optimal design of structures under fatigue-induced system failure. To further improve the efficiency of this new optimization framework, an additional bounding rule is proposed in the context of SRBDO against fatigue using the B3 method. To demonstrate the proposed method, it is applied to complex problems, a multilayer Daniels system and a three-dimensional tripod jacket structure. The system failure probability of the optimal design is confirmed to be below the target threshold and verified using Monte Carlo simulation. At earlier stages of the optimization, a smaller number of limit-state function evaluation is required, which increases the efficiency. In addition, the proposed method can allocate limited materials throughout the structure optimally so that the optimally-designed structure has a relatively large number of failure paths with similar failure probability.

Atmospheric Corrosion Model of Carbon Steel Considering Relative Humidity, Chloride Deposition Rate, and Surface Particles (상대 습도, 염화물 누적률, 표면 입자를 고려한 탄소강의 대기부식 모델)

  • Jinsoo Shin;Hyeok-Jun Kwon;Hongseok Kim;Dooyoul Lee
    • Corrosion Science and Technology
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    • v.23 no.4
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    • pp.324-333
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    • 2024
  • Atmospheric corrosion poses a significant threat to durability of metallic materials and safety of structures, making precise prediction of corrosion rates crucial in industrial and engineering settings. Understanding the exact rate of corrosion is essential. However, accurate inclusion of various environmental factors that can influence atmospheric corrosion in the calculation of corrosion rate is a complex challenge. This study introduces a physics-based model that incorporates electrochemical methods and considers active surface area affected by surface contaminants to estimate atmospheric corrosion rate of carbon steel. The model can evaluate corrosion levels using key factors such as chloride deposition rate, relative humidity, and the presence of surface particles. By integrating these considerations, this model moves beyond empirical estimations, providing a more stable prediction of corrosion rate that is less susceptible to environmental variations. This model provides a robust tool for defense applications, offering precise insights into the dynamics of atmospheric corrosion that could enhance the maintenance and safety of weapon systems.

Immunological Responses of Broiler Chicks Can Be Modulated by Dietary Supplementation of Zinc-methionine in Place of Inorganic Zinc Sources

  • Moghaddam, Hasan Nassiri;Jahanian, Rahman
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.3
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    • pp.396-403
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    • 2009
  • Male broiler chicks were fed graded levels of organic zinc (zinc-methionine) supplementation to investigate the effects of partial or complete substitution of the organic zinc source for inorganic ones on the development of lymphoid organs and immunological responses. A total of 450 day-old male broilers were distributed into groups of 10 chicks and randomly assigned to nine experimental diets during a 42-day feeding trial. Dietary treatments consisted of two basal diets supplemented with 40 mg/kg added zinc as feed-grade Zn sulfate or Zn oxide in which, Zn was replaced with that provided from zinc-methionine (ZnMet) complex at the levels of 25, 50, 75 or 100%. Two randomly-selected birds from each pen replicate were bled and then slaughtered by cervical cutting on the final day of the trial to measure leukocyte subpopulations and relative weights of lymphoid organs. Among lymphoid organs, only thymus weight was affected (p<0.05) by dietary treatments. The sulfate-supplemented birds were heavier (p<0.01) in relative weight of thymus than oxide-supplemented birds. The 10 days of age-assessed cutaneous hypersensivity reaction was stronger in chicks fed ZnMet-containing diets. Dietary ZnMet supplementation caused (p<0.05) an increase in proportion of lymphocytes and consequently a decrease in heterophil to lymphocyte ratio. Diet fortification by zinc-methionine complex increased (p<0.01) Newcastle antibody titer at 19 days of age. Also, a similar response was observed in antibody titers at 6 and 12 d after infectious bronchitis vaccine administration. There was no significant effect of replacement of dietary zinc on antibody titer against infectious bursal disease virus (IBDV) at the 6th d post-vaccine inoculation; however, at d 12 after vaccination, ZnMet-fortified diets improved antibody titer against IBDV. Although dietary inclusion of ZnMet had no marked effect on primary antibody titer against sheep erythrocytes, effective responses were observed during secondary reaction from the viewpoint of both total antibody and immunoglobulin Y (IgY) titers. From the present findings, it can be concluded that dietary supplementation with organic zinc improves both cellular and humoral immune responses. It is necessary to replace 75% of supplemental inorganic zinc with organic ZnMet complex to achieve the optimum immunological responses in broiler chicks.

Study on Stabilization of Retinaldehyde using Drug-in-Cyclodextrinin-Liposome (DCL) for Skin Wrinkle Improvement (레틴알 안정화를 위한 사이클로덱스트린-리포좀에 관한 연구)

  • Ha, Ji Hoon;Choi, Hyeong;Hong, In Ki;Han, Sang-Kuen;Bin, Bum Ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.1
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    • pp.77-85
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    • 2022
  • Retinaldehyde (RA), vitamin A derivative, is an intermediate between retinol and retinoic acid and has an excellent wrinkle improving effect. In this study, Drug-in-cyclodextrin-in-liposome (DCL) was used to enhance the stability and skin penetration of RA. The complex of RA and hydroxypropyl-beta-cyclodextrin (HP-β-CD) was prepared by the freeze-drying method, and the presence or absence of inclusion of retinal was confirmed by UV-Vis spectrometer, FT-IR and SEM images. RA was captured in HP-β-CD about 95.6% on 1 : 15 (w/w). The retinal-HP-β-CD complex was encapsulated in liposomes using a homomixer and microfluidizer, with an average particle size of 215 ± 4.2 nm and a zeta potential of -31.2 ± 0.5 mv. In the evaluation of the degradation stability of RA, degradation rate of RA-HP-β-CD-liposomes in water was 1.8% higher than RA-liposome (5.8%), RA-HP-β-CD complex (9.7%) and RA alone (37.6%). RA cream (0.05% RA) including RA-HP-β-CD-liposomes was prepared for clinical test with wrinkle-improving efficacy and skin dermis denseness evaluated for 2 or 4 weeks. RA cream showed a significant wrinkle improving effect without skin irritation. In conclusion, it was confirmed that the double stabilization technology using the DCL system contribu tes to the effect of improving skin wrinkles by increasing the stabilization of retinal.

Genetic Environments of Hydrothermal Copper Deposits in Ogsan Mineralized Area, Gyeongsangbukdo Province (경북 옥산지역 열수동광상의 성인연구)

  • Choi, Seon-Gyu;Choi, Sang-Hoon;Yun, Seong-Taek;Lee, Jae-Ho;So, Chil-Sup
    • Economic and Environmental Geology
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    • v.25 no.3
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    • pp.233-243
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    • 1992
  • Ore mineralization of the Hwanghak copper deposit in the Ogsan area occurred in three stages of quartz (stage I and II) and calcite (stage III) veining along fissures in Early Cretaceous sedimentary rocks. Ore minerals are pyrite, pyrrhotite, chalcopyrite (dominant), sphalerite, hematite, galena, and Ag-, Pb-, and Bi-sulfosalts. These were deposited during the first stage at temperatures between $370^{\circ}C$ and < $200^{\circ}C$ from fluids with salinities between 0.5 and 7.6 equiv. wt. % NaCl. There is evidence of boiling and this suggests pressures of less than 180 bars during the first stage. Equilibrium thermodynamic interpretation accompanying with mineral paragenesis and fluid inclusion data indicates that copper precipitation in the hydrothermal system occurred due to cooling and changing in chemical conditions ($fs_2$, $fo_2$, pH). Gradual temperature decrease from $350^{\circ}$ to $250^{\circ}C$ of ore fluids by boiling and mixing with less-evolved meteoric waters mainly led to copper deposition through destabilization of copper chloride complexes. Sulfur isotope values of sulfide minerals decrease systematically with paragenetic time from calculated ${\delta}^{34}S_{H_2S}$ values of 8.2 to 4.7‰. These values, together with the observed change from sulfide-only to sulfide-hematite assemblages and fluid inclusion data, suggest progressively more oxidizing conditions, with a corresponding increase of the $sulfate/H_2S$ ratio of hydrothermal fluids. Measured and calculated hydrogen and oxygen isotope valutls of ore-forming fluids suggest meteoric water dominance, approaching unexchanged meteoric water values.

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Study on the Coefficient of Thermal Expansion for Composites Containing 3-Dimensional Ellipsoidal Inclusions (3차원적 타원 형태의 충전제를 함유하는 복합체의 열팽창 계수 연구)

  • Lee, Kee-Yoon;Kim, Kyung-Hwan;Jeoung, Sun-Kyoung;Jeon, Hyoung-Jin;Joo, Sang-Il
    • Polymer(Korea)
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    • v.31 no.3
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    • pp.206-214
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    • 2007
  • The theoretical study is developed for predicting the thermal expansion changes of composites which include complex inclusion, which is used three-dimensional ellipsoid model ($a_1>a_2>a_3$), which has two aspect ratios (the primary aspect ratio, $\rho_{\alpha}=a_1/a_3$ and the secondary aspect ratio, $\rho_{\beta}=a_1/a_2$). We can predict the feature of general thermal expansion factors by theoretical approach of matrix with aligned ellipsoidal inclusion using the Eshelby's equivalent tensor. The coefficients of longitudinal linear thermal expansion ${\alpha}_{11}$ decrease to those of inclusions, ${\alpha}_f$, as both aspect ratios increase. The coefficients of transverse linear thermal expansion of composites ${\alpha}_{33}$ initially increase and show the parabolic corves with maximum values, as the concentrations of filler increase. The coefficient of thermal expansion, ${\alpha}_{22}$ in the transverse direction decreases, as $\rho_{\alpha}$ increases, however, ${\alpha}_{22}$ increases as $\rho_{\beta}$ increases. The coefficient of linear thermal expansion of composites, ${\alpha}_{33}$ in the normal direction increases, as $\rho_{\alpha}$ increases, while ${\alpha}_{33}$ decreases as $\rho_{\beta}$ increases.

Fluid Inclusion and Stable Isotope Studies of Mesothermal Gold Vein Deposits in Metamorphic Rocks of Central Sobaegsan Massif, Korea: Youngdong Area (소백산 육괴 중부 지역의 변성암에서 산출되는 중온형 금광상에 대한 유체 포유물 및 안정동위원소 연구. 영동지역)

  • Chip-Sup So
    • Economic and Environmental Geology
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    • v.32 no.6
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    • pp.561-573
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    • 1999
  • Mesothermal gold deposits of the Heungdeok, Daewon and Ilsaeng mines in the Youngdong area occur in fault shear zones in Precambrian metamorphic rocks of central Sobaegsan Massif, Korea, and formed in single stage of massive quartz veins (0.3 to 3 m thick). Ore mineralogy is simple, consisting dominantly of pyrrhotite, sphalerite and galena with subordinate pyrite, chalcopyrite, electrum, tetrahedrite and native bismuth. Fluid inclusion data indicate that hydrothermal mineralization occurred at high temperatures (>240$^{\circ}$ to 400$^{\circ}$C) from $H_{2}O-CO_{2}(-CH_{4})$-NaCI fluids with salinities less than 12 wt. % equiv. NaC!. Fluid inclusions in vein quartz comprise two main types. These are, in decreasing order of abundance, type I (aqueous liquid-rich) and type II (carbonic). Volumetric proportion of the carbonic phase in type II inclusions varies widely in a single quartz grain. Estimated $CH_4$ contents in the carbonic phase of type II inclusions are 2 to 20 mole %. Relationship between homogenization temperature and salinity of fluid inclusions suggests a complex history of fluid evolution, comprising the early fluid's unmixing accompanying $CO_2$ effervescence and later cooling. Estimated pressures of vein filling are at least 2 kbars. The ore mineralization formed from a magmatic fluid with the ${\delta}^{34}S_{{\Sigma}S}$, ${\delta}^{18}O_{water}$ and ${\delta}D_{water}$ values of -2.1 to 2.2$\textperthousand$, 4.7 to 9.3$\textperthousand$ and -63 to -79$\textperthousand$, respectively. This study validates the application of a magmatic model for the genesis of mesothermal gold deposits in Youngdong area.

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Preparation and Characterization of the Multi-functionalized Mask Pack (다기능성 마스크 팩의 제조 및 특성평가)

  • Kim, Soo-Yeoun;Bae, Jun-Won;Ha, Jae-Soon;An, Hyo-Jeong;Kweon, Tae-Yeon;Choi, Seong-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.1
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    • pp.333-340
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    • 2019
  • This paper was described about the preparation of the multi-functional mask pack and its evaluation. Here, the multi-functional effects means the far-infrared emissivity effect due to polyphosphoric acid, the freckles treatment effect and peeling effects due to inclusion complexes, and the skin temperature decreasing effect due to Lavender-extraction compounds. The the hazardous chemicals, viscosity, and pH were determined blow 0.01%, 280 cP, and pH=6.92 in the prepared multi-functional mask pack solution, respectively. The multi-functional mask pack prepared with dipping method in the solution were showed the value of $0.882{\mu}m$ (Far-infrared emissivity) and $3.40{\times}10^2W/m$ at $37^{\circ}C$ (Far-infrared radiation energy), respectively. After taking multi-functional mask pack, the skin moisturizing rate was indicated 35.5%, and the skin temperature was showed in the range of $24{\sim}26^{\circ}C$. The skin stimulation test for the 30 volunteer was showed very strong stability.

A Prognostic Factor for Prolonged Mechanical Ventilator-Dependent Respiratory Failure after Cervical Spinal Cord Injury : Maximal Canal Compromise on Magnetic Resonance Imaging

  • Lee, Subum;Roh, Sung Woo;Jeon, Sang Ryong;Park, Jin Hoon;Kim, Kyoung-Tae;Lee, Young-Seok;Cho, Dae-Chul
    • Journal of Korean Neurosurgical Society
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    • v.64 no.5
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    • pp.791-798
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    • 2021
  • Objective : The period of mechanical ventilator (MV)-dependent respiratory failure after cervical spinal cord injury (CSCI) varies from patient to patient. This study aimed to identify predictors of MV at hospital discharge (MVDC) due to prolonged respiratory failure among patients with MV after CSCI. Methods : Two hundred forty-three patients with CSCI were admitted to our institution between May 2006 and April 2018. Their medical records and radiographic data were retrospectively reviewed. Level and completeness of injury were defined according to the American Spinal Injury Association (ASIA) standards. Respiratory failure was defined as the requirement for definitive airway and assistance of MV. We also evaluated magnetic resonance imaging characteristics of the cervical spine. These characteristics included : maximum canal compromise (MCC); intramedullary hematoma or cord transection; and integrity of the disco-ligamentous complex for assessment of the Subaxial Cervical Spine Injury Classification (SLIC) scoring. The inclusion criteria were patients with CSCI who underwent decompression surgery within 48 hours after trauma with respiratory failure during hospital stay. Patients with Glasgow coma scale 12 or lower, major fatal trauma of vital organs, or stroke caused by vertebral artery injury were excluded from the study. Results : Out of 243 patients with CSCI, 30 required MV during their hospital stay, and 27 met the inclusion criteria. Among them, 48.1% (13/27) of patients had MVDC with greater than 30 days MV or death caused by aspiration pneumonia. In total, 51.9% (14/27) of patients could be weaned from MV during 30 days or less of hospital stay (MV days : MVDC 38.23±20.79 vs. MV weaning, 13.57±8.40; p<0.001). Vital signs at hospital arrival, smoking, the American Society of Anesthesiologists classification, Associated injury with Injury Severity Score, SLIC score, and length of cord edema did not differ between the MVDC and MV weaning groups. The ASIA impairment scale, level of injury within C3 to C6, and MCC significantly affected MVDC. The MCC significantly correlated with MVDC, and the optimal cutoff value was 51.40%, with 76.9% sensitivity and 78.6% specificity. In multivariate logistic regression analysis, MCC >51.4% was a significant risk factor for MVDC (odds ratio, 7.574; p=0.039). Conclusion : As a method of predicting which patients would be able to undergo weaning from MV early, the MCC is a valid factor. If the MCC exceeds 51.4%, prognosis of respiratory function becomes poor and the probability of MVDC is increased.

Au-Ag Minerals and Genetic Environments from the Yeongdeog Gold-Silver Deposits, Korea (영덕(盈德) 금(金)-은광상(銀鑛床)에서 산출(産出)되는 금(金)-은광물(銀鑛物)과 광상(鑛床)의 생성환경(生成環境))

  • Lee, Hyun Koo;Yoo, Bong-Cheal;Kim, Sang Jung
    • Economic and Environmental Geology
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    • v.28 no.6
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    • pp.541-551
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    • 1995
  • The Yeongdeog gold-silver deposits at Jipum, Gyeongsangbugdo, is of a middle Paleogene $(45.52{\pm}1.02Ma)$ vein type, and is hosted in shale and sandstone of Cretaceous age. Based on mineral paragenesis, vein structure and mineral assemblages, the ore mineralization can be divided into two distinct depositional stages. The early stage is associated with base-metals such as pyrite, arsenopyrite (27.99~30.99 at%), hematite, rutile, pyrrhotite, sphalerite (10.53~18.42 FeS mole%), chalcopyrite and galena with wallrock alteration such as chlorite, sericite and pyrite. The late stage is characterized by the Au-Ag mineralization such as electrum, Ag-bearing tetrahedrite, freibergite, pyrargyrite, unidentified mineral, pyrite, sphalerite (1.08~5.57 FeS mole%), chalcopyrite and galena. Fluid inclusion data indicate that fluid temperatures and salinities range from 343 to $227^{\circ}C$ and from 8.3 to 5.7 wt% eq. NaCl in early stage, respectively. Temperatures and salinities of NaCl eq. wt% range from 299 to $225^{\circ}C$ and from 12.9 to 4.3 in late stage, respectively. They suggest that complex cooling histories were occured by the mixing of the fluids. Sulfur fugacity $(-logfs_2)$ deduced by mineral assemblages and composition ranges from 8.3 to 14.7 atm. in early stage, and from 8.8 to 14.5 atm. in late stage. It suggests that the mineralization was related to decrease of temperature in early stage and fluctuations of $fS_2$ with decrease of temperature in late stage. Sulfur and oxygen isotope compositions are 4.48~5.60‰ and 9.25~10.8% in early stage, and late stage is 4.84~7.00‰ and 5.7‰, respectively. It indicated that hydrothermal fluids may be magmatic origin with some degree of mixing of another water during paragenetic time.

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