• Title/Summary/Keyword: In-folding Structure

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A Study on the Formative Characteristics of the Pleats Expressed in Modern Fashion -Focusing on the Thought of G.W.Leifniz and G.Deleuze- (현대 패션에 나타난 주름의 조형적 특성에 관한 연구 -라이프니츠와 들뢰즈를 중심으로-)

  • Yang, Hee-Young;Yang, Sook-Hi
    • Journal of the Korean Society of Costume
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    • v.57 no.1 s.110
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    • pp.130-146
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    • 2007
  • Thought of postmodernism accepted between variety and differentiation is characterized by variability and indeterminacy aimed at continuous change. For that reason, modern fashion has been grouping a lot of manners for creation of the various different form and structure. This paper studies the characteristics of the folding system, which expands efficiency of the spatial utility and shows various forms. Folding system expressed in modern fashion could be divided the pleats, which were made of the folding, and the dreaperies, which were made of bending. This selects the pleats as a enlarged concept of the folding system that contains between the former and the letter. Pleats did not mean two dimensional folding surfaces, but three dimensional spatial structures. For understanding of the folding system as a three dimensional spatial structure, this is utilized with the thought of the 'le pli' of G.W.Leifniz and G.Deleuze. The pleats expressed in modern fashion can subdivided into 4 sets; crinkle system, origami system, fractal pleats by folding system, and drapery system. And Formative characteristics of the pleats are analyzed with enlargement, fluidity, deconstruction, irregularity.

Structure-based Functional Discovery of Proteins: Structural Proteomics

  • Jung, Jin-Won;Lee, Weon-Tae
    • BMB Reports
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    • v.37 no.1
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    • pp.28-34
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    • 2004
  • The discovery of biochemical and cellular functions of unannotated gene products begins with a database search of proteins with structure/sequence homologues based on known genes. Very recently, a number of frontier groups in structural biology proposed a new paradigm to predict biological functions of an unknown protein on the basis of its three-dimensional structure on a genomic scale. Structural proteomics (genomics), a research area for structure-based functional discovery, aims to complete the protein-folding universe of all gene products in a cell. It would lead us to a complete understanding of a living organism from protein structure. Two major complementary experimental techniques, X-ray crystallography and NMR spectroscopy, combined with recently developed high throughput methods have played a central role in structural proteomics research; however, an integration of these methodologies together with comparative modeling and electron microscopy would speed up the goal for completing a full dictionary of protein folding space in the near future.

The structural method of modular system expressed in contemporary fashion design (현대 패션디자인에 표현된 모듈러 시스템의 구조방식)

  • Yoon, Jeong-A;Lee, Younhee
    • The Research Journal of the Costume Culture
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    • v.22 no.5
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    • pp.776-793
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    • 2014
  • This study attempted to figure out the usage of the modular system in other fields through literature review and empirical study, analyze its structural method in fashion. After analyzing architecture & product-related books, the Internet data and previous studies, the modular system's five structural methods were obtained. Then, 991 photos of women's clothes from 2003 to 2014 were collected through the fashion websites in Korea and abroad. The results can be summarized as follows: First, the following five structures were derived: assembling structure, overlapping structure, arrangement structure, inserting structure and folding structure. Second, according to analysis on the structural method of the modular system in modern fashion, overlapping structure (34%) was the most common. Third, in fashion, the use of fastener for installation and removal is important for assembling structure. In terms of overlapping structure, 3D volume by vertical accumulation was commonly observed. Arrangement structure revealed a horizontal and flat shape through simple arrangement. In inserting structure, on the contrary, non-standardized modules were used as a part of clothes or decorative elements. In folding structure, origami technique for reduction and expansion was used.

A Study on Folding Furniture through the Structure of Hinges (경첩구조를 이용한 접이식 가구에 관한 연구)

  • 조남주
    • Journal of the Korea Furniture Society
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    • v.12 no.2
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    • pp.81-90
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    • 2001
  • For opening and shutting function, door has some hardware such as hinges and the locks. The folding mechanism of hinges represent mobility, and the lock means stability. The opening and shutting door-the mobility-could be interpreted the movement from flat state to three-dimensional structure. The folding mechanism also would be understood variable feature to the space. This study focus on the Folding Furniture which adapted the good point of hinges to make efficient use of the space. The folding furniture presented in this study has not only artistic meaning which expand and apply structural function of hinges, but also flexible reanalysis on the environment and the space which change with social, economic and cultural trend.

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Biochemical and NMR Characterization of MTH1880 Mutant Proteins for Folding-Unfolding Studies

  • Kim, Hee-Youn;Ryu, Soo-Young;Yun, Ji-Hye;Kim, Suhk-Mann;Chang, Ik-Soo;Lee, Weon-Tae
    • Bulletin of the Korean Chemical Society
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    • v.31 no.12
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    • pp.3521-3524
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    • 2010
  • MTH1880 is a hypothetical protein derived from Methanobacterium thermoautotrophicum, thermophilic methanogen. The solution structure determined by NMR spectroscopy showed that it has a novel $\alpha+\beta$-fold with a highly acidic ligand binding pocket. Since MTH1880 maintains its ultra-stable structural characteristics at both high temperature and pressure, it has been considered as an excellent model for studying protein folding. To initiate the structural and folding study of MTH1880 in proving its unusual stability, we performed the site directed mutagenesis and biochemical analysis of MTH1880 mutants. Data from circular dichroism and NMR spectroscopy suggest that the point mutations perturbed the structural stability of protein even though the secondary structure is retained. This study will provide the useful information in understanding the role of participating residues during folding-unfolding process and our result will be used in designing further folding experiments for hyper-thermopile proteins like MTH1880.

Partially Folded States of Mutant Ubiquitin in Mild Denaturing Conditions

  • Park, Soon-Ho
    • Bulletin of the Korean Chemical Society
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    • v.30 no.7
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    • pp.1567-1572
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    • 2009
  • Conformational change of ubiquitin variant with valine to alanine mutation at sequence position 26 was studied by varying solvent pH. Fluorescence emission spectra indicated that this variant ubiquitin has some residual structures in acidic and basic solution as compared to denaturant-induced unfolded state. Far-UV circular dichroic spectra indicated that the base-denatured state had more secondary structure than the acid-denatured state. Near-UV circular dichroic spectra indicated that the aromatic side-chains were in the relatively more rigid environment in the base-denatured state than those in the acid-denatured state. Although it appears that the more tertiary structure present in the base-denatured state, refolding reactions measured by stopped-flow fluorescence device suggest that both the acid- and base-denatured states occur before the major folding transition state. The acid- and base-denatured states are considered to reflect the early event of protein folding process.

글루타치온 생산효소( $\gamma$-Glutamylcysteine Synthetase)와 그 변이효소의 구조분석 및 반응 Kinetics 연구

  • Yang, Hye-Jeong;Gwon, Dae-Yeong
    • Bulletin of Food Technology
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    • v.17 no.4
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    • pp.98-106
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    • 2004
  • Two mutant enzymes of $\gamma$-glutamylcysteine synthetase ($\gamma$-GCS) which catalyzed the synthesis of $\gamma$-glutamylcysteine from L-glutamic acid and L-cysteine in the presence of ATP, were prepared bypoint mutation of $\gamma$-GCS gene with site-directed mutagensis in E. coli. Conformational structuresand catalytic reaction kinetics of mutant enzymes were compared with wild type $\gamma$-GCS afterpurification. The S495F mutant enzyme (serine at 495 residue was substituted with phenylalanine),which had no catalytic activity for $\gamma$-glutamylcysteine synthesis, rarely folded even in neutral pH.However, the mutant A494V (alanine of 494 residue was replaced by valnine) which showed 50 %increase of activity, had a high folding structure. The folding structure of A494V also more stable athigh temperature and extreme pH compared to wild type and S495F. Reaction kinetics of wild typeand A494V were also investigated, Km value of A494V was smaller than that of wild type, while itshowed a little difference at Vmax values. This result evolved that alanine at 494 may be involved inbinding site of substrate rather than catalytic site. In addition, change of catalytic activity by onepoint mutation was highly correlated with the folding structure of enzyme.

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A 9-Bit 80-MS/s CMOS Pipelined Folding A/D Converter with an Offset Canceling Technique

  • Lee, Seung-Chul;Jeon, Young-Deuk;Kwon, Jong-Kee
    • ETRI Journal
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    • v.29 no.3
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    • pp.408-410
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    • 2007
  • A 9-bit 80-MS/s CMOS pipelined folding analog-to-digital converter employing offset-canceled preamplifiers and a subranging scheme is proposed to extend the resolution of a folding architecture. A fully differential dc-decoupled structure achieves high linearity in circuit design. The measured differential nonlinearity and integral nonlinearity of the prototype are ${\pm}0.6$ LSB and ${\pm}1.6$ LSB, respectively.

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Understanding β-Hairpin Formation: Computational Studies for Three Different Hairpins

  • Lee, Jin-Hyuk;Shin, Seok-Min
    • Bulletin of the Korean Chemical Society
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    • v.29 no.4
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    • pp.741-748
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    • 2008
  • We have studied the folding mechanism of $\beta$ -hairpins in the proteins 1GB1, 3AIT and 1A2P by conducting unfolding simulations at moderately high temperatures. The analysis of trajectories obtained from molecular dynamics simulations in explicit aqueous solution suggests that the positions of the hydrophobic core residues lead to subtle differences in the details of folding dynamics. However, the folding of three different hairpins can be explained by a unified mechanism that is a blend of the hydrogen-bond-centric and the hydrophobiccentric models. The initial stage of $\beta$-hairpin folding involves various partially folded intermediate structures which are stabilized by both the van der Waals interactions of hydrophobic core residues and the electrostatic interactions of non-native hydrogen bonds. The native structure is obtained by forming native contacts in the final tune-up process. Depending on the relative positions of the hydrophobic residues, the actual mechanism of hairpi n folding may or may not exhibit well-defined intermediates.

A study on folding chairs' structure (접이식 의자의 구조 연구)

  • 강명선;조숙경
    • Journal of the Korea Furniture Society
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    • v.13 no.1
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    • pp.42-47
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    • 2002
  • The folding chairs are one of the most necessary furniture for satisfying the moderns' wants which is utilized for limited space rationally. These folding chairs are variously used in interior spaces such as offices, dining areas, and resting areas. They are very easy to move around, so that quiet useful in out door areas, too. Moreover, they play an important role in public spaces as supplementary furniture. The folding chairs have one or several axes, and they are classified according to type of axes like below. 1. Method of divide seating board into 2 and fold, 2. Method of folds seating board and lay on bottom of backboard, 3. Method of fold back board and lay on top of seating board, 4. Method of fold into contact with left and right, 5. Method of gathering legs into one and fold. The folding chairs have to be easy to operate, firm and safe, light for moving around easily, designed for able to change units whenever they have damaged. Change of residential spaces according to the trend towards the nuclear family maximized necessity of limited spaces' use. Therefore, this study provides insights for development of new methods' of folding chairs.

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