• Bulletin of the Korean Mathematical Society
• /
• v.56 no.2
• /
• pp.391-397
• /
• 2019

In this paper, we give a simple proof of the improved Johnson bound for A(n, d), the maximum number of codewords in a binary code of length n and minimum distance d, given by Mounits, Etzion and Litsyn.

• Molecules and Cells
• /
• v.39 no.7
• /
• pp.536-542
• /
• 2016

Interleukin-17A is a member of the IL-17 family, and is known as CTLA8 in the mouse. It is produced by T lymphocytes and NK cells and has proinflammatory roles, inducing cytokine and chemokine production. However, its role in tumor biology remains controversial. We investigated the effects of locally produced IL-17A by transferring the gene encoding it into CT26 colon cancer cells, either in a secretory or a membrane-bound form. Expression of the membrane-bound form on CT26 cells dramatically enhanced their proliferation in vitro. The enhanced growth was shown to be due to an increased rate of cell cycle progression: after synchronizing cells by adding and withdrawing colcemid, the rate of cell cycle progression in the cells expressing the membrane-bound form of IL-17A was much faster than that of the control cells. Both secretory and membrane-bound IL-17A induced the expression of Sca-1 in the cancer cells. When tumor clones were grafted into syngeneic BALB/c mice, the tumor clones expressing the membrane-bound form IL-17A grew rapidly; those expressing the secretory form also grew faster than the wild type CT26 cells, but slower than the clones expressing the membrane-bound form. These results indicate that IL-17A promotes tumorigenicity by enhancing cell cycle progression. This finding should be considered in treating tumors and immune-related diseases.

• Journal of Information Technology Applications and Management
• /
• v.22 no.2
• /
• pp.1-17
• /
• 2015

In this research, we develop and suggest branch and bound algorithms for a two-machine permutation flowshop scheduling problem with the objective of minimizing makespan. In this scheduling problem, after each job is operated on the machine 1 (first machine), the job has to start its second operation on machine 2 (second machine) within its corresponding limited waiting time. In addition, each job has its corresponding ready time at the machine 1. For this scheduling problem, we develop various dominance properties and three lower bounding schemes, which are used for the suggested branch and bound algorithm. In the results of computational tests, the branch and bound algorithms with dominance properties and lower bounding schemes, which are suggested in this paper, can give optimal solution within shorter CPU times than the branch and bound algorithms without those. Therefore, we can say that the suggested dominance properties and lower bounding schemes are efficient.

• Transactions of Materials Processing
• /
• v.6 no.6
• /
• pp.517-526
• /
• 1997

The purpose of this study is to investigate changes in the wall thickness of tube sinking and working forces by the upper bound method and ABAQUS code. The independent variables are ; workpiece material, original wall thickness of tube, die angle, friction, and reduction of diameter. The results indicate that these five variables are factors of the increase in wall-thickness and working forces. Three variables, a inner tube wall angle and two angles of the velocity discontinuous surfaces, are optimized in this proposed velocity field by the upper bound method. In this method, we can estimate the working forces and final tube thicknesses similar to actual forming process. Optimum process variables which are obtained by upper bound method are used in ABAQUS pre-model.

• Management Science and Financial Engineering
• /
• v.16 no.1
• /
• pp.81-117
• /
• 2010

Semi-supervised learning incorporates unlabeled examples, whose labels are unknown, as well as labeled examples into learning process. Although transductive support vector machine (TSVM), one of semi-supervised learning models, was proposed about a decade ago, its application to large-scaled data has still been limited due to its high computational complexity. Our previous research addressed this limitation by introducing a branch-and-bound algorithm for finding an optimal solution to TSVM. In this paper, we propose three new techniques to enhance the performance of the branch-and-bound algorithm. The first one tightens min-cut bound, one of two bounding strategies. Another technique exploits a graph-based approximation to a support vector machine problem to avoid the most time-consuming step. The last one tries to fix the labels of unlabeled examples whose labels can be obviously predicted based on labeled examples. Experimental results are presented which demonstrate that the proposed techniques can reduce drastically the number of subproblems and eventually computational time.

• BMB Reports
• /
• v.36 no.2
• /
• pp.154-158
• /
• 2003

Collagen is a family of proteins which consists of several genetically distinct molecular species and is intimately involved in tissue organization, function, differentiation and development. The purpose of this study was to investigate the concentration of different hydroxyproline (Hyp) fractions viz., total, free, peptide-bound, protein-bound, soluble- and insoluble-collagen hydroxyproline (Hyp) in various bovine tissues. Results showed that liver had the highest concentration of free Hyp followed by kidney, brain, spleen, lungs, muscle and heart. Liver also had the highest concentration of peptide-bound collagen Hyp followed by kidney, heart, spleen, lungs, brain and muscle. The concentration of protein-bound collagen Hyp was highest in the liver, followed by kidney, spleen, lungs, muscle, brain and heart. Total Hyp was highest in the liver, followed by kidney, spleen, brain, heart, muscle and lungs. Liver also had significantly high concentration of collagen as compared to other tissues examined (P<0.001). Spleen had the significantly higher concentration of soluble-collagen Hyp when compared to other tissues (P<0.001). This was followed by heart, muscle, lungs, brain, kidney and liver. Heart had the highest concentration of insoluble-collagen Hyp followed by lungs, kidney, liver, muscle, spleen and brain. The variation among the insoluble-collagen Hyp concentration of heart and muscle, spleen and brain was significant (P<0.001). We speculate that these differences could be due to the variation in turn over of rate of collagen metabolism in this species.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.31 no.1
• /
• pp.17-27
• /
• 2019

We carry out the numerical simulation to test a hypothesis that freak waves can be triggered by the infragravity waves of bound mode underlying the ever-present swells and its constructive interaction with swells using the Tool Box called the ihFoam that has its roots on the OpenFoam, and Bi-spectrum. Numerical simulation is implemented for the SamChcuk LNG Plant where freak waves have been reported in front of the private wharf during its construction phase due to the uncompleted northern breakwater. Infra-gravity waves of bound mode is generated using the difference wave-wave interaction between the local wind waves of 7 s and a swell of 11.4 s based on the Bi-spectrum. For the sake of comparison, numerical simulation for infra-gravity waves of free mode is also carried out. Numerical results show that stem waves along the private wharf for SamChcuk LNG Plant can be triggered by the infra-gravity waves of bound mode coming from the north, which eventually leads to freak waves when encounters the reflected waves from the south jetty.

• Proceedings of the Korea Society for Energy Engineering kosee Conference
• /
• 2003.05a
• /
• pp.431-435
• /
• 2003

Because the Tissue Bound Tritium of food irradiates the organic tissues of a man during a longer time than the Tissue Free Water Tritium, we found the ratio of labile and bound hydrogen, which is the direct source of TBT concentration, in grain such as rice and barley. Tissue free water was extracted from rice and barley sampled, adjacent to Wolsung nuclear power plants of CANDU type, by freeze-drying. Tissue bound water was taken from some of the dried samples by high-pressure combustion. The other of the samples was washed by tritium-free water for 2-3 hours, and dried again by freeze-drying. Tissue bound water was taken again from some of the second dried samples by the combustion. The extracted tissue free and bound waters were distilled and TFWT and TBT concentrations of them were counted by a liquid scintillation counter. Through alternating washing, drying and combustion until the concentration of TBT would be constant, the tritium concentration existing as bound hydrogen was found. The ratios of labile and bound hydrogen of rice and barley were determined by TR concentration, initial TBT concentration and bound tritium concentration. The ratios of bound hydrogen of rice and barley were 0.55, 0.60 relatively.

• Bulletin of the Korean Mathematical Society
• /
• v.38 no.4
• /
• pp.797-801
• /
• 2001

The purpose of this paper is to give an upper bound for A[n,4], the maximum number of codewords in a binary code of word length n with minimum distance 4 between codewords. We have improved upper bound for A[12k+11,4]. In this correspondence we prove $A[23,4]\leq173716$.

• Communications of the Korean Mathematical Society
• /
• v.20 no.2
• /
• pp.405-409
• /
• 2005

In [1], Sharma and Goel obtained a bound for random error correcting codes with Lee weight considerations. The purpose of this paper is to first point out a discrepancy in this result and then give a correct version of the same, improving upon the bound tremendously.