• 한국막학회:학술대회논문집
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• 한국막학회 2004년도 Proceedings of the second conference of aseanian membrane society
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• pp.65-68
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• 2004

Molecular imprinting, which was first proposed by Wulff and Sarhan in 1972 [1], is a facile way to construct molecular recognition sites by applying a simple radical polymerization [2]. Since 1994, the authors have proposed an alternative molecular imprinting method in which polymeric materials are directly converted into molecular recognition materials [3].(omitted)

• Asian-Australasian Journal of Animal Sciences
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• 제16권8호
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• pp.1087-1092
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• 2003

As an experimental reference population, crosses between Korean native pig and Landraces were established and information on growth traits was recorded. Animals were genotyped for 24 microsatellite markers covering chromosomes 2, 6, and 7 for partial-genome scan to identify chromosomal regions that have effects on growth traits. quantitative trait loci (QTL) effects were estimated using interval mapping by the regression method under the line cross models with a test for imprinting effects. For test of presence of QTL, chromosome-wide and single position significance thresholds were estimated by permutation test and normal significance threshold for the imprinting test were derived. For tests against the Mendelian model, additive and dominance coefficients were permuted within individuals. Thresholds (5% chromosome-wide) against the no-QTL model for the analyzed traits ranged from 4.57 to 4.99 for the Mendelian model and from 4.14 to 4.67 for the imprinting model, respectively. Partial-genome scan revealed significant evidence for 4 QTL affecting growth traits, and 2 out of the 4 QTLs were imprinted. This study demonstrated that testing for imprinting should become a standard procedure to unravel the genetic control of multi-factorial traits. The models and tests developed in this study allowed the detection and evaluation of imprinted QTL.

• 한국전기화학회:학술대회논문집
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• 한국전기화학회 2003년도 추계총회 및 학술발표회
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• pp.73-73
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• 2003

• Journal of Information Display
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• 제13권2호
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• pp.55-59
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• 2012

In this paper, a concept of an integrated elastomer substrate for a three-dimensional (3D) liquid crystal display based on the integral-imaging method is presented. The elemental lens array and columnar spacers were integrated into one of the two substrates, an elastomer substrate, through an imprinting process. The integrated elastomer substrate was capable of maintaining the uniform liquid crystal (LC) cell gap and promoting homeotropic LC alignment without any surface treatment. The monolithic approach reported herein will provide a key component for 3D displays with enhanced portability through a more than 40% weight reduction compared with the conventional integral-imaging method.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.172-172
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• 2006

Molecular imprinting constitutes a valuable method of preparing polymeric materials with specific binding properties. The most conspicuous merit of molecular imprinting is that structurally three-dimensional recognition sites can be introduced into a polymer matrix with ease and low cost when compared with the complicated process of biological system for antigen and antibody. We used a thermally reversible bond for the preparation of the monomer-template complex, which allowed us to remove the template easily by means of a simple thermal reaction and to simultaneously introduce various functional groups into the cavity. This method is especially propitious for developing artificial receptors for molecules lacking strongly interactive groups.

• 한국진공학회지
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• 제19권2호
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• pp.96-104
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• 2010

NIL, S-FIL과 같은 각인 기술(Imprinting lithography)를 적용하기 위한 투명하고 단단한 복제 틀(replica hard mold)을 제작하여 고가의 원판(master)와 패턴이 형성되는 기판과의 접촉을 근본적으로 방지해 경제적인 공정이 가능함을 제안한다. 실리콘 웨이퍼(Si wafer)와 같은 원판(master)과 패턴 형성 시 사용되는 기판과 직접적인 접촉을 방지하기 위해 우선 액상 공정을 이용하여 비접착성 표면처리된 고분자 복제(polymer copy)를 매개체(carrier)로 단단한 복제 틀을 제작한다. 이렇게 제작된 단단한 복제 틀(replica hard mold)는 유리와 거의 같은 강도와 투명도를 나타내며, 각인 공정(imprinting process)에서 석영 틀, 실리콘 웨이퍼(quartz mold, Si wafer)과 같이 값비싼 원판(master)의 직접 사용을 대체하여 성공적으로 패턴을 구현할 수 있다.

• 생명과학회지
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• 제21권4호
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• pp.549-553
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• 2011

본 연구는 선행연구에서 molecular imprinting 방법을 이용하여 개발한 1-OHP 인식 $TiO_2$-Bead가 실제 소변중의 1-OHP를 효율적으로 검출할 수 있는지 평가하기 위해서 시행되었다. 본 연구에서 개발한 분석 방법은 within-day 변이계수가 4.97%, between-day 변이계수가 4.43%로 나타나 본 측정방법이 매우 안정적인 방법임을 확인할 수 있었다. 1-OHP와 유사한 물질들이 혼합된 용액으로부터 $TiO_2$-Bead-HPLC 측정방법의 회수율을 평가한 결과, 평균 105.6%의 회수율을 나타내었다. 실제 소변시료를 대상으로 기존의 효소-HPLC 측정방법과 본 측정방법 간의 상관성을 평가한 결과, 두 방법 간에는 높은 상관관계(r=0.74, p<0.01)를 보여 bead를 이용한 요중 1-OHP의 새로운 측정 방법의 유용성을 확인할 수 있었다. 본 연구에서 개발한 새로운 측정방법은 기존의 측정방법에 비해 요중 1-OHP 농도를 보다 간편하고 저렴한 가격으로 측정할 수 있다는 장점이 있다. 본 연구의 결과는 $TiO_2$ 코팅 bead를 응용한 요중 1-OHP 센서의 개발에 응용할 수 있을 것으로 생각되며, 분자주형을 이용한 bead의 개발은 1-OHP 이외의 다른 화학물질의 분석에도 다양하게 응용할 수 있을 것으로 기대된다.

• 대한세포병리학회지
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• 제1권1호
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• pp.36-42
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• 1990

The fluoroscopy-guided fine needle aspiration biopsy has been gaining widespread acceptance as a rapid and effective method to make a pre-operative diagnosis of mediastinal tumors including thymoma, malignant lymphoma, and metastatic carcinoma. Although thymoma is a most common tumor of the superior mediastinum, most cytopathologists are not experted in cytologic diagnosis of this tumor because of limited experience. In order to define the diagnostic cytologic features of thymoma, we have retrospectively reviewed imprinting smears and corresponding tissue sections from four cases of this tumor. All cases revealed an apparent biphasic pattern of epithelial cell clusters and lymphocytes with occasional branching capillary fronds extending from three dimensional epithelial cell clusters. Epithelial cell clusters predominated in one case and lymphocytes in two cases. Mixed epithelial cell and lymphocyte type represented in one of four cases. In the lymphocyte predominant type, the presence of epithelial cell clusters and small mature lymphocytes are helpful features to differentiate from a malignant lymphoma.

• Journal of Information Display
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• 제9권4호
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• pp.11-14
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• 2008

A highly efficient organic light-emitting diode (OLED) with an in-cell polarizer made of an imprinted liquid crystalline polymer (LCP) layer doped with dichroic dye molecules is presented. The in-cell polarizer was found to be capable of effectively polarizing the emission light of the OLED and of significantly improving the luminance through the periodic microstructures fabricated using an imprinting method. This type of OLED with an imprinted in-cell polarizer is useful for efficient light source applications in liquid crystal displays (LCDs).

• KSBB Journal
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• 제20권3호
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• pp.133-141
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• 2005

This review presents the preparation, transport mechanism and application of molecularly imprinted membranes (MIM). Molecular imprinting has now been established as a technique which allows the creation of tailor-made binding sites for many classes of compounds. MIM have some advantages; a high capacity due to a large surface area, faster transport of substrate molecules and faster equilibrium of binding cavities compared to molecularly imprinted particles. MIM were prepared by covalent and non-covalent chemical bonding systems, by interactions between functional monomer and template. MIM can be prepared by in-situ polymerization, wet phase inversion, dry phase inversion, and surface imprinting method. MIM can continuously separate mixtures based on facilitated or retarded diffusion of the template. MIM can change their permeability in the presence of templates. MIM have a potential to be used to separate chiral compounds and materials with similar structures. However the application of MIM by the chemical industries is still in its infancy stages.