• BMB Reports
• /
• 제50권4호
• /
• pp.164-174
• /
• 2017

Mitochondria are cytosolic organelles essential for generating energy and maintaining cell homeostasis. Despite their critical function, the handful of proteins expressed by the mitochondrial genome is insufficient to maintain mitochondrial structure or activity. Accordingly, mitochondrial metabolism is fully dependent on factors encoded by the nuclear DNA, including many proteins synthesized in the cytosol and imported into mitochondria via established mechanisms. However, there is growing evidence that mammalian mitochondria can also import cytosolic noncoding RNA via poorly understood processes. Here, we summarize our knowledge of mitochondrial RNA, discuss recent progress in understanding the molecular mechanisms and functional impact of RNA import into mitochondria, and identify rising challenges and opportunities in this rapidly evolving field.

• Journal of Korea Port Economic Association
• /
• 제23권4호
• /
• pp.228-243
• /
• 2007

This study porvides an empirical overview of the import patterns of Incheon port using an Engle-Granger cointegration technique and Johansen's multivariate cointegraion methodology test to check the stationarity of the model. The empirical results show that the import in Incheon port related to the economic variables. This paper also applies rolling regression to our model, indicating that import are endogeneous to the economic variable.

• Proceedings of the Korean Society of Life Science Conference
• /
• 한국생명과학회 2002년도 제37회 국제학술심포지움 및 추계학술대회
• /
• pp.36-39
• /
• 2002

PKB activation may contribute to resistance to antiproliferative signals and breast cancer progression in part by impairing nuclear import and action of p27. PKB transfection caused cytoplasmic p27 accumulation and cytokine resistance. The nuclear localization region of p27 contains a PKB/Akt consensus site at threonine 157 and p27 phosphorylation by PKB impaired its nuclear import in vitro. PKB/Akt phosphorylated wild type p27 but not p27T157A. PKB activation led to cytoplasmic mislocalization of p27WT but p27T157A remained nuclear. In PKB activated cells, p27WT failed to cause Gl arrest, while the antiproliferative effect of p27T157A was not impaired. Cytoplasmic p27 was seen in 41% (52/128) of primary human breast cancers in association with PKB activation. Thus, we show a novel mechanism whereby PKB impairs p27 function that is associated with an aggressive phenotype in human breast cancer.

• Journal of Biosystems Engineering
• /
• 제31권3호
• /
• pp.194-202
• /
• 2006

Using a multi-variable linear regression technique and SUR(seemingly unrelated regression) model, the demand functions of tractor, combine and rice transplanter were estimated. The demand was regarded as an annual supply of each machine and modeled as a function of 11 independent variables which reflect the actual farmer's income, actual prices of farm machines, previous supply, previous stock, actual amount of available subsidy, actual amount of available loan, arable land, import of farm machines and rice price. The actual amount of available loan affects most significantly the demand functions. The actual farmer's income, actual farmer's asset, loan coverage, and rice price affect the demand positively while prices of farm machines and import negatively. The annual demands of tractor, combine and rice transplanter estimated using the demand functions were also presented over the next 4 years.

• Environmental and Resource Economics Review
• /
• 제18권4호
• /
• pp.715-744
• /
• 2009

This study was analyzed the change of the tariff reduction for the Korea's fishery according to the Non Agricultural Market Access(NAMA) negotiations of the WTO. Four scenarios of tariff liberalization of NAMA are conducted on the basis of a Swiss formula. Using import demand function, we estimated price elasticities of imported fishery. The results of the analysis with mark up 20% show that, in the position of developed member, the value of import increase was between 405 billion won and 439 billion won, and analyzed between 232 billion won and 254 billion won with less than cut 50%. On the other hand, in the position of developing country, the value of import increase was between 311 billion won and 356 billion won, and analyzed between 174 billion won and 201 billion won with less than cut 50%. Also, the results was showed that the highest effects for increasing value of import are a fresh Pollack.

• Journal of Internet Computing and Services
• /
• 제3권4호
• /
• pp.19-26
• /
• 2002

Workflow Management Systems(WFMSs) is a software system that supports that specification and execution of business processes. In this paper, we proposed Multi Agent Based Workflow Modeling System which was implemented by Java application. The proposed workflow modeling system is divided into four agents; Session, Organization, Relevant Data. Invoked Application. We adapted ICN(Information Control Net) to check workflow model syntax, And the proposed modeling system provide the function to import/export WPDL which was defined in WfMC.

• Journal of the Korean Operations Research and Management Science Society
• /
• 제6권1호
• /
• pp.57-64
• /
• 1981

The continuous increase of crude oil consumption has struck great impact into the world economy, When we consider disadvantageous articles in contract for oil import, it would be desirable to import in batch the total quantity of crude oil contracted, but which is not available under the present situation which has many constraints This paper treats of the ways to deliver the crude oil in a given period so as to maximize the profit derived from the sales of oil products, To do this we should consider the prices of crude oil and oil products, inventory cost, transportation cost, oil refinement cost, and fluctuations of these parameters in a given period. The case of Korea Oil Corporation is treated in this paper to generalize the problem of crude oil transportation from Middle East and formulated in a mathematical programming. This programming is transformed into Dynamic Programming through specifing states, stages, payoffs, and recursive function. To clarify these procedure and methods, the case of Korea Oil Corporation is dealt with again and demonstrated in detail.

• International Commerce and Information Review
• /
• 제10권3호
• /
• pp.459-474
• /
• 2008

Under violent competition to secure international raw materials, safe supply and demand of crude oil that only relies on import among main raw materials is an important task for Korean economic development. Therefore, this study aims to analyze the impact of price change of international crude oil on merchandise balance. It also presents political suggestions in preparation for national economic development and safety and develops an organized and long-term overseas resources development program. As the time-series data which had the 1st difference contribute to dismissal of the null hypothesis successfully, we carry out a multivariate cointegration test developed by Johansen (1988) and find that at least one cointegration vector exists. And, when Impulse Response Function is introduced, as the crude oil import price shows a negative impact from Step 2, then an extreme change, a positive impact since Step 13, is maintained and a safe result appears.

• The Journal of Fisheries Business Administration
• /
• 제38권3호
• /
• pp.89-108
• /
• 2007

The purpose of the study are summarized as follows: First, it has researched the new functions of middleman in Fisheries Port Market. Second, the new functions which middleman have to perform in Fisheries Port Market consist of the origin function, marketing function, logistics function. The origin function consists of the discrimination of fish species and freshness, making the price by auction, financing, etc. Marketing function consists of various species assortment from not only fisheries port market but also non fisheries port market as frozen and import fish markets, finding the new selling markets as not broker but wholesaler, making the price and margin non through the action, processing, etc. Logistics function consist of fish stock, delivery Third, it has recognized the upcoming important problems by building up the new functions as middleman in Fisheries port Market. This study has used a questionnaire to verify 3 hypotheses. Research model, factor analysis, regression analysis. The result of this study are summarized as follows: The origin function influences positively on the effectiveness of middleman's performance in Fisheries port Market. Marketing function influences positively on the effectiveness of middleman's performance. However, logistics function did not directly influences on the effectiveness of middleman's performance.

• Journal of Oriental Physiology
• /
• 제14권2호통권20호
• /
• pp.139-148
• /
• 1999

In this paper, tiangui was considered in it's conception, generation and physiological function according to successive physicians. The following results were obtained : 1. Over the years, there have been many ideas about tiangui. These days, it is proper that tiangui be thought of as some substance which is in shenjing and which promotes generative function. According to current endocrinologic view, tiangui is equivalent to GnRH. 2. Before birth, a parent's energy is inherited to the embryo and after birth, that energy becomes tiangui which is sustained by taking food and nutrition. Tiangui is especially related to shenjing. 3. The most import physiological function of tiangui is the promotion of generative function. So it is related to menstruation and ejaculation. Secondly, tiangui is also concerned with human's growth and development.