• Journal of Biomedical Engineering Research
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• v.30 no.3
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• pp.233-240
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• 2009

Using a spatial compound imaging technique in a medical ultrasound imaging system, the average speed of sound in a medium of interest is measured, and imaging of its distribution is implemented. When the brightness reaches the highest level in an ultrasonic image obtained as the speed of sound used in focusing is varied, it turns out that the focusing has been accomplished satisfactorily and that the speed of sound which has been adopted becomes the sought-after average speed of sound. Because spatial compound imaging provides many different views of the same object, the adverse effect of erroneous speed-of-sound estimation tends to be more severe in compound imaging than in plain B-mode imaging. Thus, in compound imaging, the average speed of sound even in the case of speckled images can be accurately estimated by observing the brightness change due to different speeds of sound employed. Using this new method that offers spatial diversity, we can construct an image of the speed of sound distribution in a phantom embedded with a 10-mm diameter plastic cylinder whose speed of sound is different from that of the background. The speed of sound in the cylinder is found to be different from that of the surrounding medium.

• Clinical Endoscopy
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• v.51 no.6
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• pp.527-533
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• 2018

There have been many advances in endoscopic imaging technologies. Magnifying endoscopy with narrow-band imaging is an innovative optical technology that enables the precise discrimination of structural changes on the mucosal surface. Several studies have demonstrated its usefulness and superiority for tumor detection and differential diagnosis in the stomach as compared with conventional endoscopy. Furthermore, magnifying endoscopy with narrow-band imaging has the potential to predict the invasion depth and tumor margins during gastric endoscopic submucosal dissection. Classifications of the findings of magnifying endoscopy with narrow-band imaging based on microvascular and pit patterns have been proposed and have shown excellent correlations with invasion depth confirmed by microscopy. In terms of tumor margin prediction, magnifying endoscopy with narrow-band imaging offers superior delineation of gastric tumor margins compared with traditional chromoendoscopy with indigo carmine. The limitations of narrow-band imaging, such as the need for considerable training, long procedure time, and lack of studies about its usefulness in undifferentiated cancer, should be resolved to confirm its value as a complementary method to endoscopic submucosal dissection. However, the role of magnifying endoscopy with narrow-band imaging is expected to increase steadily with the increasing use of endoscopic submucosal dissection for the treatment of gastric tumors.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.11
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• pp.1054-1062
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• 2011

This study describes the time domain imaging algorithm which can be well applied to short-range UWB(ultra wideband) bistatic radar. In the imaging method of SAR technology, the frequency domain method is well applied to the areas which satisfy far-field condition. However in the near-field environment, the image quality is not good due to phase error. However back-projection method based on time domain is well applied to short-range imaging radar. Meanwhile because its processing time is very long, real time-processing is very difficult. To resolve this problem FFBP(Fast Factorized Back-Projection) was proposed. Using the raw data gathered on field we implemented back-projection and FFBP method. Then image quality and processing time were analyzed using these methods.

• BMB Reports
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• v.48 no.12
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• pp.655-667
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• 2015

Lineage tracing is a widely used method for understanding cellular dynamics in multicellular organisms during processes such as development, adult tissue maintenance, injury repair and tumorigenesis. Advances in tracing or tracking methods, from light microscopy-based live cell tracking to fluorescent label-tracing with two-photon microscopy, together with emerging tissue clearing strategies and intravital imaging approaches have enabled scientists to decipher adult stem and progenitor cell properties in various tissues and in a wide variety of biological processes. Although technical advances have enabled time-controlled genetic labeling and simultaneous live imaging, a number of obstacles still need to be overcome. In this review, we aim to provide an in-depth description of the traditional use of lineage tracing as well as current strategies and upcoming new methods of labeling and imaging.

• Journal of the Optical Society of Korea
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• v.20 no.2
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• pp.228-233
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• 2016

In this paper, we propose a nonlinear maximum average correlation height (MACH) filter for information authentication of photon counting double random phase encryption (DRPE). To enhance the security of DRPE, photon counting imaging can be applied because of its sparseness. However, under severely photon-starved conditions, information authentication of DRPE may not be implemented successfully. To visualize the photon counting DRPE, a three-dimensional imaging technique such as integral imaging can be used. In addition, a nonlinear MACH filter can be utilized for helping the information authentication. Therefore, in this paper, we use integral imaging and nonlinear MACH filter to implement the information authentication of photon counting DRPE. To verify our method, we implement optical experiments and computer simulation.

• Ceramist
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• v.22 no.3
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• pp.269-280
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• 2019

Ceramic layered double hydroxide (LDH) nanohybrids have attracted considerable interest in biomedical science due to their unique structural feature and characteristics in biological condition. Many studies on LDH nanoparticles have been reported in diagnosis applications including magnetic resonance imaging (MRI) contrast agents in order to not only provide better imaging performance through multimodal imaging strategy, but realize therapeutic function which treat cancers in one platform. This review highlights the recent progress in MRI T₁ contrast agent, dual modal imaging system, and MRI-guided drug delivery systems ranging from synthetic method and characterization to evaluation in vitro and in vivo based on the ceramic LDH nanohybrids. Future research directions are also suggested for next-generation bio-imaging contrast agent.

• Proceedings of the IEEK Conference
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• 2008.06a
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• pp.995-996
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• 2008

This paper proposes a algorithm that generate the intermediate scene from the stereo image. This system based on mesh representation method, and segmented objects which ar calculated from triangles the pro proposed algorithm is composed of two steps. One is triangle grouping using gestalt theory, and the other is disparity estimation using average disparity of segmented object. We make an experiment on the proposed algorithm with some stereo images and obtain good quality disparity map for intermediate scenes.

• Laser Solutions
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• v.10 no.1
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• pp.29-34
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• 2007

We propose a novel application of laser engraving to patterning of light guide panel (LGP) for backlight. The feasibility of three-dimensional engraved pattern in the LGP was verified by measuring brightness and uniformity. To improve the overall uniformity, we have modified proposed patterns and found improved design for patterns. The tailoring of pattern by using laser engraving method could endow the controllability of uniformity. The proposed LGPs are more efficient in both average brightness and uniformity of illumination than the conventional LGPs which have surface pattern on the panel.

• Korean Journal of Veterinary Service
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• v.30 no.2
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• pp.205-209
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• 2007

A protein chip based on surface plasmon resonance (SPR) imaging was developed for measuring classical swine fever virus (CSFV) antibody using a recombinant gp55 protein as an antigen. The diagnostic potential of SPR imaging for detecting antibodies to the CSFV gp55 protein was compared with that of a enzyme -linked immunosorbent assay (ELISA) using 70 pig sera. There was a strong positive correlation between the SPR imaging and ELISA (n=70, r=0.916, p<0.01). Therefore, the SPR imaging, which is a label-free and high-through put method, is expected to be a valuable tool in the serodiagnosis of CSFV.

• Korean Journal of Digital Imaging in Medicine
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• v.15 no.1
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• pp.27-31
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• 2013

Perfusion MR imaging is how to use exogenous and endogenous contrast agent. Exogenous perfusion MRI methods which are dynamic susceptibility contrast using $T2^*$ effect and dynamic contrast-enhanced using T1 weighted image after injection contrast media. An endogenous perfusion MRI method which is arterial spin labeling using arterial blood flow in body. In order to exam perfusion MRI in human, technical access are very important according to disease conditions. For instance, dynamic susceptibility contrast is used in patients with acute stroke because of short exam time, while dynamic susceptibility contrast or dynamic contrast enhancement provides the various perfusion information for patients with tumor, vascular stenosis. Arterial spin labeling is useful for children, women who are expected to be pregnant. In this regard, perfusion MR imaging is required to understanding, and the author would like to share information with clinical users