• 대한방사선치료학회:학술대회논문집
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• 대한방사선치료학회 2005년도 학술집담회 초록집
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• pp.31-31
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• 2005

• 대한방사선치료학회지
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• 제33권
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• pp.109-116
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• 2021

목 적: 본 연구는 표면유도환자셋업(Surface-Guided Patient Setup, SGPS)을 활용한 Markerless환자(피부에 표시를 시행하지 않은 환자)와 레이저기반환자셋업(Laser-Based Patient Setup, LBPS)을 활용한 Marker환자(피부에 표시를 시행한 환자)를 영상유도방사선치료(Image Guided Radiotherapy, IGRT)로 시행했을 때 환자 위치 정확도를 비교하여 SGPS의 유용성을 평가하는데 목적이 있다. 대상 및 방법: 3개의 카메라를 이용한 광학 표면 스캐닝시스템을 사용하여 SGPS로 초기 셋업한 Markerless 환자와 환자 피부에 그려진 Marker와 레이저를 정렬하는 LBPS로 초기 셋업한 Marker환자의 IGRT시 위치 오차를 비교하였다. SGPS,LBPS 모두 각각 전립선암 환자 20명, 뇌정위적방사선수술(Stereotactic Radiation Surgery, SRS) 환자 10명을 대상으로 시행하였고 SGPS의 경우는 추가로 유방암 환자 60명을 대상으로 시행하였다. 모두 CBCT 또는 OBI를 사용하여 IGRT를 시행하였다. 자동위치교정시스템(Auto-Matching System)을 이용하여 6방향(6 Degree Of Freedom, 6 DoF)의 위치 오차를 획득하였고 치료계획시스템에서 Offline-Review를 이용하여 비교, 분석하였다. 결 과 : 전립선암환자의 SGPS와 LBPS의 RMS(Root Mean Square) 차이는 Vrt -0.02cm, Log -0.02cm, Lat -0.01cm, Pit -0.01°, Rol -0.01°, Rtn -0.01°이였고 SRS 환자는 Vrt 0.02cm, Log -0.05cm, Lat 0.00cm, Pit -0.30°, Rol -0.15°, Rtn -0.33°으로 두 부위 모두 큰 차이가 없었다. 유방암환자의 IGRT기준 RMS는 Vrt 0.26, Log 0.21, Lat 0.15, Pit 0.81, Rol 0.49, Rtn 0.59으로 나타났다. 결 론 : 본 연구의 결과 LBPS 대비 SGPS의 위치 오차 값은 전립선암 환자와 SRS 환자의 경우 큰 차이를 보이지 않았다. 추가로 실시한 SGPS의 유방암 환자의 경우에도 IGRT기준으로 위치 오차 값이 크지 않았다. 따라서 환자 피부 표시를 필요로 하지 않는 큰 장점을 가진 SGPS로 LBPS를 대체하기에 유용할 것으로 사료된다.

• Imaging Science in Dentistry
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• 제39권3호
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• pp.149-156
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• 2009

Purpose : The purpose of this study was to develop a stent-based image guided surgery system and to apply it to oral and maxillofacial surgeries for anatomically complex sites. Materials and Methods : We devised a patient-specific stent for patient-to-image registration and navigation. Three-dimensional positions of the reference probe and the tool probe were tracked by an optical camera system and the relative position of the handpiece drill tip to the reference probe was monitored continuously on the monitor of a PC. Using 8 landmarks for measuring accuracy, the spatial discrepancy between CT image coordinate and physical coordinate was calculated for testing the normality. Results : The accuracy over 8 anatomical landmarks showed an overall mean of $0.56{\pm}0.16\;mm$. The developed system was applied to a surgery for a vertical alveolar bone augmentation in right mandibular posterior area and possible interior alveolar nerve injury case of an impacted third molar. The developed system provided continuous monitoring of invisible anatomical structures during operation and 3D information for operation sites. The clinical challenge showed sufficient accuracy and availability of anatomically complex operation sites. Conclusion : The developed system showed sufficient accuracy and availability in oral and maxillofacial surgeries for anatomically complex sites.

• Journal of Korean Neurosurgical Society
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• 제63권2호
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• pp.237-247
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• 2020

Objective : Fixation of the C1-2 segment is challenging because of the complex anatomy in the region and the need for a high degree of accuracy to avoid complications. Preoperative 3D-computed tomography (CT) scans can help reduce the risk of complications in the vertebral artery, spinal cord, and nerve roots. However, the patient may be susceptible to injury if the patient's anatomy does not match the preoperative CT scans. The intraoperative 3D image-based navigation systems have reduced complications in instrument-assisted techniques due to greater accuracy. This study aimed to compare the radiologic outcomes of C1-2 fusion surgery between intraoperative CT image-guided operation and fluoroscopy-guided operation. Methods : We retrospectively reviewed the radiologic images of 34 patients who underwent C1-2 fusion spine surgery from January 2009 to November 2018 at our hospital. We assessed 17 cases each of degenerative cervical disease and trauma in a study population of 18 males and 16 females. The mean age was 54.8 years. A total of 139 screws were used and the surgical procedures included 68 screws in the C1 lateral mass, 58 screws in C2 pedicle, nine screws in C2 lamina and C2 pars screws, four lateral mass screws in sub-axial level. Of the 34 patients, 19 patients underwent screw insertion using intraoperative mobile CT. Other patients underwent atlantoaxial fusion with a standard fluoroscopy-guided device. Results : A total of 139 screws were correctly positioned. We analyzed the positions of 135 screws except for the four screws that performed the lateral mass screws in C3 vertebra. Minor screw penetration was observed in seven cases (5.2%), and major pedicle screw penetration was observed in three cases (2.2%). In one case, the malposition of a C2 pedicle screw was confirmed, which was subsequently corrected. There were no complications regarding vertebral artery injury or onset of new neurologic deficits. The screw malposition rate was lower (5.3%) in patients who underwent intraoperative CT-based navigation than that for fluoroscopy-guided cases (10.2%). And we confirmed that the operation time can be significantly reduced by surgery using intraoperative O-arm device. Conclusion : Spinal navigation using intraoperative cone-beam CT scans is reliable for posterior fixation in unstable C1-2 pathologies and can be reduced the operative time.

• 대한방사선기술학회지:방사선기술과학
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• 제41권3호
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• pp.209-214
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• 2018

The results of CBCT was obtained using image guided radiation therapy for radiation therapy in 5 prostate cancer patients. Using these results, we compared and evaluated the dose changes according to the treatment plan depending on the volume and position of bladder, rectum, and prostate. The 28 images of CBCT were acquired using On-Board Imaging device before radiotherapy. After the outline of bladder, rectum, and PTV, pCT images and CBCT images for radiotherapy were treated respectively. The volume of the bladder was increased by 105.6% and decreased by 45.2%. The volume of the rectum was increased by 30.5% and decreased by 20.3%. Prostate volume was increased by 6.3% and decreased by 12.3%. The mean dose of the rectum was higher in the CBCT than in the pCT, and V40 (equivalent to 40 Gy) of the bladder showed a reduction in all treatment regimens in the CBCT than in the pCT. Conformity treatment and homogeneity index of PTV showed better results in all treatment regimens using pCT than CBCT. It was found that the dose distribution of the pelvic internal organs varied greatly according to the patient 's condition and pretreatment.

• 한국정보통신학회논문지
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• 제23권4호
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• pp.365-373
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• 2019

본 논문은 정밀 유도무기에 장착되어 목표물 명중 확률을 좌우하고, 비용적인 측면에서 유도무기의 가장 큰 부분을 차지하는 적외선 영상탐색기에 대한 성능 대비 개발비용 최적화에 대한 연구이다. 탐색기 개발 비용의 주요항목인 해상도와 그에 따른 탐지성능에 영향을 미치는 인자들을 분석함으로써, 설계 단계에서 해상도 별 탐지성능과 개발 비용과의 상관관계를 분석하는 연구를 수행하였다. 다양한 신호 대 클러터 비 조건에서 해상도 별 표적탐지 확률을 설계 시 중요인자로 정의하고, 개발비용 선정의 기준이 되는 해상도 별 탐지성능 분석을 수행하였으며, 탐지성능 확보를 위한 최적의 해상도와 그에 따른 투입비용에 대한 관계를 도출하였다. 다양한 클러터 환경에 따른 사례연구를 통하여 제안한 분석 방식이 탐지성능 만족을 위하여 요구되는 개발비용 예측에 효과적임을 검증하였으며, 유도무기 운용 환경에서 성능대비 최적화된 개발비용을 설계단계에서 미리 도출할 수 있는 연구 자료로 활용하고자 한다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제5권4호
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• pp.856-873
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• 2011

Reversible watermarking is an open problem in information hiding field, with embedding the encoded bit '1' or '0' into some sensitive images, such as the law enforcement, medical records and military images. The technique can retrieve the original image without distortion, after the embedded message has been extracted. Histogram-based scheme is a remarkable breakthrough in reversible watermarking schemes, in terms of high embedding capacity and low distortion. This scheme is lack of capacity control due to the requirement for embedding large-scale data, because the largest hidden capacity is decided by the amount of pixels with the peak point. In this paper, we propose a reversible watermarking scheme to enlarge the number of pixels with the peak point as large as possible. This algorithm is based on an adaptive edge-guided interpolation, furthermore, hides messages by interpolation-error, i.e. the difference between the original and interpolated image value. Simulation results compared with other state-of-the-art reversible watermarking schemes in this paper demonstrate the validity of the proposed algorithm.

• 대한방사성의약품학회지
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• 제8권2호
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• pp.113-118
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• 2022

Gadolinium neutron capture therapy (Gd-NCT) is a precision radiation therapy that kills cancer cells using the neutron capture reaction that occurs when ¹⁵⁷Gd hits thermal neutrons. ¹⁵⁷Gd has the highest thermal neutron capture cross section of 254,000 barns among stable isotopes in the periodic table. Another stable isotope, ¹⁵⁵Gd, also has a high thermal neutron trapping area (~ 60,700 barns), so gadolinium that exists in nature can be used as a Gd-NCT drug. Gd-NCT is a mixed kinetic energy of low-energy and high-energy ionizing particles, which can be uniformly distributed throughout the tumor tissue, thereby solving the disadvantage of heterogeneous dose distribution in tumor tissue. The Gd complexes of small-sized molecule are widely used as contrast agents for magnetic resonance imaging (MRI) in clinical practice. Therefore, these compounds can be used not only for diagnosis but also therapy when considering the concept of Gd-NCT. This multifunctional trial can look forward to new medical advance into NCT clinical practices. In this review, we introduce gadolinium compounds suitable for Gd-NCT and describe the necessity of image guided Gd-NCT.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2016년도 제54차 하계학술대회논문집 24권2호
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• pp.289-291
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• 2016

본 논문에서는 VR의 발전과 함께 주목받고 있는 컴퓨터 비전 관련 기술들에 대하여 살펴보고, 가장 먼저 선행되어야 하는 이미지 필터링 알고리즘에 대하여 살펴 본다. 다양한 case에서의 여러 Image Filter를 구현, 성능을 비교 분석해 보고, 정확도를 향상 시킬 수 있는 방안에 대하여 연구한다.

• 한국가스학회지
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• 제15권3호
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• pp.11-18
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• 2011

유도초음파는 구조물의 장거리 탐상에 널리 사용되고 있으며 탐촉자의 중심주파수와 판의 두께에 따라 유도 초음파의 군속도가 바뀌는 어려움으로 인하여 최근에 많은 연구자들에 의해 유도초음파를 이용한 판과 같은 구조물 진단에 토모그래피 영상화기법에 관심을 기울이고 있다. 기존에 개발된 영상화 기법으로는 Delay and Sum영상화 기법이 있으며, 수 년간 판 구조물 영상화 기법의 알고리즘으로 이용되었다. MVDR(Minimum Variance Distortionless Response) 영상화 기법은 초음파의 산란특성을 고려한 영상화 기법으로써, 빔의 특성이 영상화 알고리즘에 적용되어 Delay and Sum 영상화 기법보다 향상된 영상을 판구조물에 존재하는 홀 결함 영상을 통해 비교 분석하였다.