• Journal of the Korea Society of Computer and Information
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• v.27 no.10
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• pp.267-274
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• 2022

The purpose of this study is to investigate the learning satisfaction and perception of the students who have taken the online classes of the Digital Innovation Sharing University in the field of new energy industry, and to analyze the relationship between the learning satisfaction and core competencies. In order to achieve this purpose, the results of the learning satisfaction survey of a total of 470 students who took the digital innovation sharing university classes in the new energy industry were analyzed in both quantitative and qualitative methods. As a result of quantitative analysis, students' learning satisfaction was generally above average, and they were particularly satisfied with the setting and operation of educational goals. In addition, it was found that students' learning satisfaction had a statistically significant effect on students' core competencies. As a result of the qualitative analysis, it was possible to confirm the direction of improvement of the curriculum in the areas of function, operation, and content. Based on the results of this study, it is expected that the digital innovation sharing university curriculum quality management feedback system will be prepared in the future, and it will be the foundation for the continuous establishment of the curriculum quality management system.

• Journal of Nutrition and Health
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• v.55 no.6
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• pp.617-629
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• 2022

Purpose: Osteoporosis is characterized by structural deterioration of the bone tissue because of the loss of osteoblastic activity or the increase in osteoclastic activity, resulting in bone fragility and an increased risk of fractures. Hederagenin (Hed) is a pentacyclic triterpenoid saponin isolated from Dipsaci Radix, the dried root of Dipsacus asper Wall. Dipsaci Radix has been used in Korean herbal medicine to treat bone fractures. In this study, we attempted to demonstrate the potential anti-osteoporotic effect of Hed by examining its effect on osteoblast differentiation in MC3T3-E1 cells. Methods: Osteoblastic MC3T3-E1 cells were cultured in 0, 1, and 10 ㎍/mL Hed for 3 and 7 days. The activity of alkaline phosphatase (ALP), bone nodule formation and level of expression of bone-related genes and proteins were measured in MC3T3-E1 cells exposed to Hed. The western blot test was used to detect the activation of the bone morphogenetic protein-2 (BMP2)/ Suppressor of Mothers against Decapentaplegic (SMAD)1 pathway. Results: Hed significantly increased the proliferation of MC3T3-E1 cells. Intracellular ALP activity was significantly increased in the 1 ㎍/mL Hed-treated group. Hed significantly increased the concentration of calcified nodules. Furthermore, Hed significantly upregulated the expression of genes and proteins associated with osteoblast proliferation and differentiation, such as Runt-related transcription factor 2 (Runx2), ALP, osteopontin (OPN), and type I procollagen (ProCOL1). Induction of osteoblast differentiation by Hed was associated with increased BMP2. In addition, Hed induced osteoblast differentiation by increasing the activity of SMAD1/5/8. These results suggest that Hed has the potential to prevent osteoporosis by promoting osteoblastogenesis in osteoblastic MC3T3-E1 cells via the modulation of the BMP2/SMAD1 pathway. Conclusion: The results presented in this study indicate that Hed isolated from Dipsaci Radix has the potential to be developed as a healthcare food and functional material possessing anti-osteoporosis effects.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.28 no.3
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• pp.95-120
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• 2023

Methane (CH₄) is a key greenhouse gas in the atmosphere with 85 times greater greenhouse potent relative to carbon dioxide (CO₂). The atmospheric concentration of CH₄ is rapidly increasing due to the intensive usage of CH₄ and the thawing of the cryosphere. Additionally, with the current warming of ocean water, the dissociation of gas hydrates, an ice-like compound and the largest reservoir of CH₄ on Earth, is expected to occur, resulting in the release of CH₄ from the seafloor into the overlying water and atmosphere. Moreover, bottom water hypoxia is another concern that potentially introduces greenhouse gases into the atmosphere. With ongoing global warming and eutrophication, the size and duration of bottom water hypoxia are rapidly increasing. These low-oxygen conditions would relocate the redox zone shallower in sediment or in the water column, causing the release of CH₄ into the atmosphere and thereby intensifying global warming. However, there exists a gap in the understanding of CH₄ dynamics including its generation in relation to bottom water hypoxia. Therefore, this review article aims to understand the relationship between CH₄ and bottom water hypoxia and to draw attention to CH₄ investigation in Korea.

• The Journal of the Acoustical Society of Korea
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• v.42 no.5
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• pp.412-421
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• 2023

Ultrasound brain stimulation is spot-lighted by its capability of inducing brain cell activation in a localized deep brain region and ultimately treating impaired brain function while the efficiency and directivity of neural modulation are highly dependent on types of stimulus waveforms. Therefore, to optimize the types of stimulation parameters, we propose a cell-cultivable ultrasonic transducer having a series stack of a spin-coated polymer piezoelectric element (Poly-vinylidene fluoride-trifluorethylene, PVDF-TrFE) and a parylene insulating layer enhancing output acoustic pressure on a glass-coverslip which is commonly used in culturing cells. Due to the uniformity and high accuracy of stimulus waveform, tens of neuronal cell responses located on the transducer surface can be recorded simultaneously with fluorescence microscopy. By averaging the cell response traces from tens of cells, small changes to the low intensity ultrasound stimulations can be identified. In addition, the reduction of stimulus distortions made by standing wave generated from reflections between the transducers and other strong reflectors can be achieved by placing acoustic absorbers. Through the proposed ultrasound transducer, we could successfully observe the calcium responses induced by low-intensity ultrasound stimulation of 6 MHz, 0.2 MPa in astrocytes cultured on the transducer surface.

• KIPS Transactions on Software and Data Engineering
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• v.12 no.8
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• pp.341-354
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• 2023

The title of a document is the brief summarization of the document. Readers can easily understand a document if we provide them with its title in their preferred styles and the languages. In this research, we propose a cross-lingual and style-based title generation model using multiple adapters. To train the model, we need a parallel corpus in several languages with different styles. It is quite difficult to construct this kind of parallel corpus; however, a monolingual title generation corpus of the same style can be built easily. Therefore, we apply a zero-shot strategy to generate a title in a different language and with a different style for an input document. A baseline model is Transformer consisting of an encoder and a decoder, pre-trained by several languages. The model is then equipped with multiple adapters for translation, languages, and styles. After the model learns a translation task from parallel corpus, it learns a title generation task from monolingual title generation corpus. When training the model with a task, we only activate an adapter that corresponds to the task. When generating a cross-lingual and style-based title, we only activate adapters that correspond to a target language and a target style. An experimental result shows that our proposed model is only as good as a pipeline model that first translates into a target language and then generates a title. There have been significant changes in natural language generation due to the emergence of large-scale language models. However, research to improve the performance of natural language generation using limited resources and limited data needs to continue. In this regard, this study seeks to explore the significance of such research.

• Iberoamérica
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• v.21 no.1
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• pp.57-105
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• 2019

This paper deals with the regional asymmetries of MERCOSUR and regional development cooperation for its solution. Through the formation of a common market, the countries of Southern Cone expected to grow evenly. However MERCOSUR had structural asymmetry from the beginning and exposed policy asymmetry over time. It is basically due to the overwhelming influences of Brazil on MERCOSUR. With regard to asymmetries, Paraguay calls for special and differential treatment. Uruguay wants equitable application of market liberalization. Argentine emphasizes production integration based on the development of value chains. In the issue of asymmetries, while Paraguay, Uruguay and Argentine act as petitioners, Brazil is capable of selecting the initiatives. Under these circumstances MERCOSUR has established FOCEM as regional redistribution mechanism. FOCEM has achieved some results as seen in Paraguay, but there are still problems such as financial limitations and lack of enforcement. In oder to activate the redistributive mechanism for regional integration and to coordinate the policies to resolve regional disparities, transnational governance is essential but all member countries are reluctant to it. To date, regional asymmetries or development gaps have persisted and disparities in individual countries remains a problem.

• Journal of Korea Entertainment Industry Association
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• v.13 no.2
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• pp.1-12
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• 2019

Based on the capabilities of smartphone cameras which have developed rapidly in recent decades, coupled with and the global market penetration rate, it will study the possibility of various international exchanges through smartphone filmmaking. This aims to achieve a civilian-oriented cultural exchange, instead of simply providing capital-oriented exchanges and film production education. The Smartphone Film Workshop was held as an auxiliary event of the Korea-Vietnam Film Festival, which ran from November 17 to 22, 2017. The three-day workshop, which took place within the festival period, drew attention for its international collaboration project between Korean film directors and Vietnamese film students. The researcher conducted practical-based research while participating as a mentor at this workshop. A step-by-step approach to the entire process of production and post-production was administered, including workshop team composition, scenario, and pre-production in Korea such as shooting equipment, schedule, completion of local works, and screening. Through an analysis of exchange cases at international workshops, we will use trial and error as ways to improve and consider the results of cultural exchanges and the effects of future expectations. Taking this empirical case study into account, we anticipate more active international exchanges through the smartphone workshops.

• Journal of Naturopathy
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• v.12 no.1
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• pp.24-30
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• 2023

Background: Arirang is a UNESCO Intangible Cultural Heritage and intangible cultural property No. 129. However, research on the origin of Arirang in Seoul is still narrowly conducted, and it is necessary to investigate it academically. Purpose: This study is to clarify the research on the origin of traditional Arirang in Seoul area on a theoretical basis. Methods: I searched various documents to find the source of Arirang in Seoul. Results: The record of 'Arirang' was first confirmed as 'Arirang Taryeong(song)' in 'Hanyang-ga' in Maecheonyarok (Maecheon's history) by Hwang (1894). After that, Hulbert (1896) published the first modern sheet music and lyrics of <A-ra-rung> on music paper. In addition, Lee Sang Jun (1914) edited <Old Korean Folk Songbook, First volume> and recorded the lyrics and score titled 'Arirang Taryeong' on page 25 and the long Arirang Taryeong. Conclusions: Literally, the origin of 'Arirang in Seoul' is 'Arirang Taryeong' first recorded in 'Hanyang-ga' of Maecheonyarok. Arirang song, which originated in Hanyang, can be called Seoul Arirang. It is suggested that Seoul Arirang has a very high value as a protected cultural heritage of Seoul because of its historical and cultural characteristics.

• Journal of Life Science
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• v.32 no.3
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• pp.256-262
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• 2022

Oxysterols are oxygenated metabolites of cholesterol generated by serial enzymatic reactions during bile acid synthesis. Similar to cholesterol, oxysterols move rapidly to the intracellular region and modulate various cellular processes, such as immune cell responses, lipid metabolism, and cholesterol homeostasis. Different nuclear transcription factors, such as glucocorticoid, estrogen, and liver X receptors, can be modulated by oxysterols in multiple tissues. The most abundant oxysterol, 27-hydroxycholesterol (27-OHC), is a well-known selective modulator that can either activate or suppress estrogen receptor activity in a tissue-specific manner. The contribution of 27-OHC in atherosclerosis development is apparent because a large amount of it is found in atherosclerotic plaques, accelerating the transformation of macrophages into foam cells that uptake extracellular modified lipids. According to previous studies, however, there are opposing opinions about how 27-OHC affects lipid and cholesterol metabolism in metabolic organs, including the liver and adipose tissue. In particular, the effects of 27-OHC on lipid metabolism are entirely different between in vitro and in vivo conditions, suggesting that understanding the physiology of this oxysterol requires a sophisticated approach. This review summarizes the potential effects of 27-OHC in atherosclerosis and metabolic syndromes with a special discussion of its role in metabolic tissues.

• Korea Trade Review
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• v.42 no.4
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• pp.69-91
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• 2017

Since the global financial crisis, major countries have been executing policies related to two top-priority goals to create more jobs: revitalization of entrepreneur activity and the cultivation of small and medium-sized companies. In South Korea, the interest of policy makers is increasingly focusing on the role of SMEs that have a technological competitive edge in the realization of a "job-centered creative economy." Due to the nature of the field, the health and medical industry requires a particularly long time until the achievement of industrialization, Also, because of the complex distribution structure, it is essential for related government ministries and institutions to jointly devise strategies. A lack of policy supports for the industry has thus far resulted in its development being relegated for the most part of small and medium-sized companies, which consequently means low global competitiveness. Now is the time for the South Korean government to provide the revolutionary supported options and strategies. This study aims to propose a general policy direction and policy areas for the cultivation of Korea's small and medium-sized companies in the healthcare industry into global small giant companies through an exploration of the German case. It is crucial to first cultivate the international competitiveness of Korean small and medium-sized companies (as in the case of Germany) so that they can grow into global small giant companies. Another important task is the creation of an environment that expedites the qualitative growth of promising SMEs as well as technological development. After securing competitiveness in terms of both product quality and technology in the global health market, substantive policy supports will be necessary to cultivate global small giant companies that are export-based (e.g. job creation effect, sales value added).