• Journal of Radiopharmaceuticals and Molecular Probes
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• v.7 no.2
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• pp.85-91
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• 2021

Selective amino acid conjugation of bulky antibodies is a valuable asset for real-time diagnosis and therapy. However, selective conjugation incorporating a chelate-bearing radioactive atom into an antibody without affecting its immunoreactivity is a challenging task. A bifunctional chelator (BFC), a selective amino acid-targeting probe, and a linker have been developed to overcome this problem. Here, we report the synthesis of a novel propylene cross-bridged chelator (PCB)-1,8-N,N'-bis-(carboxymethyl)-1,4,8,11-tetraazacyclotetradecane (TE2A)-luminol BFC via a click reaction and radiolabel it with a ⁶⁴Cu ion for tyrosine-selective conjugation of trastuzumab. In the initial optimization study, we tried different oxidative addition conditions such as electro-oxidation, hemin, horseradish peroxidase, iodogen tube, chloramine-T, and iodo beads. In this study, up to 82% of ⁶⁴Cu-PCB-TE2A-luminol was conjugated with the antibody in an iodo bead-catalyzed oxidative addition reaction with an isolated yield of 24.4%.

• Asia Marketing Journal
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• v.20 no.1
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• pp.23-48
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• 2018

SK group has been a pioneer in overall brand management and, more recently, in CSR-imbedded brand management. SK vision of "improving itself to give greater happiness to all of its customers" and the symbol mark of "Wings of Happiness" are some good examples of integrating distinct brand identities of various member companies. After impressive growth and expansions into diverse business areas, SK group is ranked as the third largest company based on asset amounts according to the Fair Trade Commission of Korea, only after Samsung and Hyundai Motor groups. SK brand management can be analyzed, using the framework of 4 stages - 'infrastructure', 'planning', 'doing', and 'seeing' stages. In order to secure 'infrastructure' of brand management system, SK has invested huge resources to the 'SK BMS' (SK Brand Management System). At the 'planning' stage, the most important task of SK like other Korean business groups is perhaps to adopt a well-organized 'brand identity (BI) system' which may consolidate brand values of individual member companies. In actuality, SK BI consists of Customer Happiness located at the center and 3 other elements of Pride, Professionalism, and Customer-orientation. At the 'doing' stage, the slogan of 'OK! SK' and the logo of 'Wings of Happiness' have been placed at the core of the SK group brand building programs. SK adopts the principle of 'independent yet united', pinpointing that each member company independently works for its business performance but it is, at the same time, encouraged to integrate its capabilities for the SK group brand. In addition, SK has sought 'shared growth' with business partners for happiness for all the members in the society. 'Social Contribution Philosophy' based on SK value of 'creation of greater happiness' is again one of the most important guidelines for CSR (corporate social responsibility) at the doing stage. At the seeing stage, SK regularly evaluates its branding programs. SK has shown some very impressive achievements in brand management: (1) a core identity of 'Customer Happiness' participating member companies may share, (2) harmonious relationships between the group brand management office and brand management divisions of member companies, and (3) consistency-keeping in brand management over time. However, there remain two major challenges: (1) globalization of SK and (2) reinforcing sustainable superiority over not only Korean rivals but also global ones.

• Journal of the Korea Society of Computer and Information
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• v.14 no.8
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• pp.127-136
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• 2009

Voice of the customer(VOC) is a term used in business and information technology(IT) to describe the process of capturing a customer's requirements in enterprises or various organizations. Recently, in order to satisfy customer's needs, enterprises try to utilize VOC at recurrence prevention of problems and their improvement activities, planning and development of product/service by processing, storing, and analyzing VOC. Until now, VOC management systems are introduced around service industries such as hotel business and insurance/financial business, etc. This paper proposes an integrated management scheme of VOC which are captured by various communication channels and describes a case of implementing an integrated VOC management system on the basis of the proposed scheme for the large-scale manufacturing company. By the implemented system, VOC are stored and utilized as the important knowledge assets of enterprises.

• The Journal of the Convergence on Culture Technology
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• v.9 no.2
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• pp.301-306
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• 2023

Convergeance in the military operations can be attained by simultaneously integrating effects based on sensor, C2, shooter asset in multi-domain and there is no exception to special operations. However, because of challenges from enemy, terrain, geopraphy, and weather, it's not easy to intertwine effects created from ground, sea, air, cyber and electromagnetic spectrum, and space in special operations conducted in deep area. This study presented how to intertwine high-tech such as long-rane reconnaissance·strike drone, cutting-edge sensor, jamming pod, and modular repeater in order to offset aforementioned challenges. Several new high-tech are able to strengthen convergeance of special operations in accordance with the development of the 4th industrial revolution. Therefore, follow-up studies need to be continued making an efforts to search for them.

• Journal of the Korean Wood Science and Technology
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• v.51 no.4
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• pp.295-308
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• 2023

This study applied a real-time IoT (Internet of Things) environmental monitoring system to wooden cultural heritages (WCHs) located in suburbs and forests in Korea. It automated the graphs of seasonal Temperature (T) and relative humidity (RH) changes inside the heritage structures and seasonal Performance Index (PI) values. While utilizing line graphs of the existing T and RH change trends and a bar graph expressing the PI values, this study examined the current status of the conservation environment inside the WCHs throughout the year and its diagnosis. Consequently, at higher latitudes, the organic cultural heritage repeatedly experienced large T fluctuations, and the risk of physical and chemical degradation of the materials was greater. However, the RH showed significant seasonal differences, even within the same latitude, indicating that the impact of latitude was not significant. Therefore, the staff in charge must manage RH by considering the surrounding environmental conditions and adjusting the internal environment of the structures. The PI values for the year-round T and RH inside the heritages were confirmed to only be a maximum of approximately 60% of the environmental suitability for conservation throughout the year, depending on the season. The relationship between the germination and growth potential period of xerophilic fungi and the monthly internal temperature and humidity in five heritages located at different latitudes was analyzed. As a result, we could thus determine that four particular months of the year (June-September) represent the periods with the highest risk of damage from xerophilic fungi in the country, regardless of latitude.

• Asia Marketing Journal
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• v.15 no.3
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• pp.141-157
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• 2013

Managing customers based on customer equity (CE) has emerged as the most effective way of doing business because of its ability to foster profitable customer relationship management (CRM) through appropriate marketing activities. Most research studies provide conceptual and empirical evidence of the positive link between CE and firm performance. However, regarding this possibility, it has been suggested by some researchers that this link may not hold true for other firms with different firmographic factors, such as firm growth rate, size, and resources. As previous research emphasizes that marketing managers should implement a strategy based on their unique business environment, our study addresses this issue by extending the framework to a different industry setting to investigate the impact of CE on firm performance. We develop a model for examining the relationship between the firm's estimated CE and firm performance by each time period using a distributed lagged model. Then, we investigate the effect of CE on the firm's profitability using a regression analysis. Finally, even though CRM is in increasing demand and firms are focusing on the customer as an asset, we conclude that there is a limited condition for this positive effect of CE. When the life cycle was divided by growth rate, CE was shown to have a distinctive effect on profit. In the case of a high-growth stage, the effect of CE on profit is positive because of its potential customer base, whereas the effect is not significant in a low-growth stage. That is, when the business environment is saturated and the firms are no longer competing in the market, CRM may not be effective. In other words, a long-term performance orientation may not be as effective as previously believed. This research contributes to the previous literature, providing a counterintuitive suggestion that firm managers should be cautious about implementing a CRM strategy and should allocate resources properly in terms of their resource capabilities and ability depending on their situation.

• Korea Trade Review
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• v.45 no.2
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• pp.229-262
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• 2020

The price-to-earnings ratio (PER) is an important indicator to measure the stock price and profitability of a firm; it is also the most used valuation indicator among investors. When using the PER to compare the investment values of different stocks, these stocks must come from the same sector. This study mainly focuses on the China's listed manufacturing firms. By learning from previous research results and analyzing the current situation, we studied the correlation between the manufacturing sector's PER and its influencing factors from both macro and micro perspectives, the combination of which eventually sheds light on such correlation. Analyzing GDP growth rate data, Manufacturing Purchasing Managers' Index, and other macroeconomic variables from 2008 to 2018, we conclude that these variables jointly have a certain impact on the average PER of the manufacturing sector. We then form panel data based on relevant (2014-2018) data gathered from 317 of China's A-listed manufacturing firms to study the impact of micro-variables on PER. By using Stata and other software to analyze the panel data, we reach the conclusion that the Debt to Asset Ratio, Return on Equity, EPS growth rate, Operating Profit Ratio, Dividend Payout Ratio, and firm size have a significant impact on PER. The Current Ratio, Treasury Stock ratio and Ownership Concentration have no distinct effect on PER. Based on our empirical findings, we design a theoretical model that affects the PER.

• Journal of Internet Computing and Services
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• v.24 no.6
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• pp.41-47
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• 2023

Financial instruments valuation continues to evolve due to various technological changes. Recently, there has been increased interest in valuation using machine learning and artificial intelligence, enabling the financial market to swiftly adapt to changes. This technological advancement caters to the demand for real-time data processing and facilitates accurate and effective valuation, considering the diverse nature of the financial market. Numerical analysis techniques serve as crucial decision-making tools among financial institutions and investors, acknowledged as essential for performance prediction and risk management in investments. This paper analyzes Korean patent trends of numerical analysis-based financial systems, considering the diverse shifts in the financial market and asset data to provide accurate predictions. This study could shed light on the advancement of financial technology and serves as a gauge for technological standards within the financial market.

• Journal of the Korea Society of Computer and Information
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• v.29 no.2
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• pp.179-195
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• 2024

The technological innovation of high-tech enterprises plays a positive driving role in operational performance. Investigating the factors influencing the operational performance of high-tech enterprises and the effects of technological innovation on operational performance is a targeted approach to promoting the growth of economic benefits and enhancing the foundation of enterprise efficiency. Additionally, it holds positive significance for the increase in market share of high-tech enterprises. This paper, considering the characteristics of high-tech enterprises, selects three influencing factors: research and development (R&D) investment intensity, the number of authorized patents, and the increment of intangible assets. Theoretical analysis is conducted on the impact mechanism and effects of these factors on operational performance. Based on this, empirical analysis is performed using relevant data of Chinese high-tech enterprises from 2011 to 2019. The study indicates that R&D investment intensity has a significant positive promoting effect on operational performance, the number of authorized patents also positively influences operational performance significantly, while the asset-liability ratio of high-tech enterprises has a notable inhibitory effect on operational performance. Finally, relevant recommendations are proposed.

• Information Systems Review
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• v.22 no.1
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• pp.73-89
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• 2020

This study started to identify the "Forward-looking" of the technology appraisal model introduced to diversify financing methods of SMEs and improve financial accessibility. The multivariate regression analysis was performed by setting the business performance(growth, profitability, and stability) of technology financing companies as dependent variables, technology appraisal items as independent variables, number of employees, age of the company, asset and the Korea Standard of Industry Classification related to firm size and industry characteristics as control variables. As a result of the analysis, the technology appraisal items did not explain the profitability of the company significantly and had a limited explanatory power on growth potential. However, in terms of stability, we confirmed that R&D capacity is a significant variable explaining the debt ratio of technology financing companies. Therefore, it is concluded that the 'Forward-looking' reflection on the growth and profitability of the company should be strengthened in the future adjustment of the technology appraisal model and the development of the technology appraisal model for investment.