• 한국의상디자인학회지
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• 제15권3호
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• pp.137-156
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• 2013

The purpose of this study is to analyze the general status of wearing clothes and clothing purchase of middle-aged women in the 40's to 50's, the patterns and colors of clothes they prefer, clothing preference related with fitting or such, and also complaints. And this paper also divides the middle-aged women into those in the 40's and 50's to analyze how they differ in terms of the apparel brands and fitting they prefer and also the status of wearing clothes. For the research, a survey was performed to 350 women, and the survey data went through x2 and t-test analysis by using SPSS 20.0 to examine significant difference. The results of this study are as follows: the women in the 40's included as the subjects showed a high frequency of clothing purchase from casual brands or SPA brands and regarded design to be important at the clothing purchase. Meanwhile, the women in the 50's indicated a higher frequency of clothing purchase of middle-aged women's apparel brands, outdoor brands, madam clothes, or designer brands and thought activity to be crucial at the clothing purchase. As the women in the 40's and 50's showed difference in the brands they preferred, particularly the fitting indicated difference in terms of dissatisfaction. While those in the 40's preferring and buying young casual showed particularly more fitting problems in the arm-hole girth, upper arm circumference, bust size, and thigh or hip area, those in the 50's indicated fitting problems in the hip circumference or waist measurement. It is expected that this study will be used as foundational data to set up the target age by related apparel companies or develop clothes with great size fitting and design satisfaction.

• 한국의류산업학회지
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• 제13권5호
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• pp.769-777
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• 2011

Anti-aging is one of the key words to have characterized Korean society, and Korean adults in their 40s and 50s are very interested in this word. In this study, their cognitive ages and body images which are expected to have been influenced by anti-ageing were determined and correlation between them was examined. A survey was conducted and 368 of 500 questionnaires were used in data analysis. Data were analyzed by descriptives, factor analysis, reliability analysis, correlation analysis, and multiple response analysis through SPSS 12.0. The results are as follows. First, the cognitive ages of Korean adults in their 40s and 50s showed to be 37.5 years old which are 9.1 years old younger than their average actual ages. Second, their attitudinal body images appeared to be composed of appearance orientation and appearance evaluation, and appearance orientation represented to be a little higher than appearance evaluation. In addition, it showed that the correlation between cognitive ages and the attitudinal body images was low and negative. Third, people in their 40s and 50s revealed to think good health and impression as ideal body images. It was found that they regarded a face as the most important body part for ideal body images and were sensitive of their weight. Forth, correlation between cognitive ages and variables of ideal body images was identified to be significant in 4 variables which are slender, shapely and slim figure and good body proportions. In conclusion, it was shown that Korean adults in their 40s and 50s recognized themselves to be 9.1 years old younger and, the younger they perceive themselves, the younger body images they want. Also, it could be confirmed that anti-ageing is a megatrend in Korean society.

• Food Science and Biotechnology
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• 제14권6호
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• pp.732-737
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• 2005

The combinational effect of gamma irradiation and moist heating on the trypsin inhibitor activity (TIA) in soaked and dried soybeans was evaluated by measuring the inhibition using N-benzoyl-DL-arginine-p-nitroanilide (BAPNA) as substrate. Gamma irradiation significantly decreased the TIA level in soybean at doses above 5 kGy, and the $ID_{50}$ (the gamma irradiation dose required to reach 50% inhibition) value for TIA was 13.53 kGy. Soaking prior to gamma irradiation significantly lowered the $ID_{50}$ to 8.44 kGy, and the soaking process enhanced the efficiency to inactivate TIA by as much as 48%. When soaking prior to gamma irradiation was followed by subsequent mild heating ($60^{\circ}C$) process, the $IT_{50}$ (heating time required to reach the 50% inhibition of TIA) value at even 1 kGy (5.28 min) was greatly reduced by over 50% compared to the level for the no-soaking process. In addition, the activation energy of soaking prior to gamma irradiation at 1 kGy was 2.45 kcal/mole, which was also about 50% lower than the 5.10 kcal/mole of dried soybean gamma-irradiated. Based on these results, soaking prior to gamma irradiation is an effective method for TIA inhibition. Furthermore, a combination of two or more processing methods such as soaking, heating and gamma irradiation is much more effective than any single processing method.

• 생명과학회지
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• 제7권3호
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• pp.198-204
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• 1997

tyrosine 인산화효소계를 통한 신호전달은 신경의 발생과 연접환성조절에 중요한 역할을 한다. 흰쥐 소뇌의 연접후치밀질에 존재하는 tyrosine 함유 당백질들을 조사하기 위하여 immunoblot 분석을 한 결과, 소뇌 연접후치밀질의 전반적인 단백질조성은 전뇌와 비슷하였다. phosphotyrosine 특이성 항체로, immunobolot 한 결과 소뇌의 주된 tyrosine 인산화 단백질은 50 kD 크기의 새로운 단백질이었다. PSD-50로 명명한 이 단백질은 SDS-PAGE에서 $\alpha$CaMKII와 같은 위치에 이동하였다. 그러나 소뇌에는 전뇌에 비하여 적은량의 $\alpha$CaMKII가 존재함에도 불구하고 전뇌보다 더 강한 phosphotyrosine immunoblot signal을 보이는 것으로 보아 PSD-50는 아마도 $\alpha$CaMKII와는 다른 단백질로 추정된다.

• 한국수산과학회지
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• 제54권3호
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• pp.293-297
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• 2021

Herein, two experiments were performed to determine the appropriate pH range and immersion time for organic acid-activating treatment (OAT) in a Pyropia farm. The effects of pH (0.50, 0.75, 1.00, 1.25, 1.50, 1.75, and 2.00) on the cell mortality of Pyropia yezoensis and Ulva linza thalli were tested after 20 sec of immersion under OAT. In addition, the cell mortality of the two species was estimated under various combinations of immersion time (30, 60, and 120 sec) and pH (1.00, 1.50, and 2.00). Upon 20 sec of immersion under OAT conditions, the cell mortality of P. yezoensis did not differ at any pH but that of U. linza exceeded 90% at a pH range of 0.50-1.00. P. yezoensis showed little cell mortality upon 30 sec of immersion, but its mortality exceeded 55% upon 120 sec of immersion at a pH range of 1.00-1.50. U. linza showed 67.9-100% mortality at a pH of 1.50 and 100% mortality at a pH of 1.00, regardless of the immersion time (30-120 sec). These results indicate that for the effective removal of U. linza, the optimal pH range is 1.00-1.50 and the optimal immersion time is 20-30 sec.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.184-184
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• 2023

Globally, agriculture is one of the largest consumers and polluters of water resources, contributing to the unsustainable use of limited water resources. To reduce the resource use and environmental footprints associated with current and future food systems, researchers and policy makers have recommended the transition to sustainable and healthier diets and the reduction of food loss and waste along the food supply chain. However, there is limited information on the synergistic effects and trade-offs of adopting the two measures. In this study, we assessed the water-saving potential of the two measures in South Korea using environmentally extended input-output relying on the EXIOBASE database for the reference year 2020, along with scenario analysis to model the potential outcomes. Specifically, we analyzed scenarios where meat consumption was reduced by 30% and 50% and in combination with a 50% reduction in food waste at the consumption stage for each scenario. According to our findings, by considering individual measures of dietary change and food waste reduction, shifting to a diet with 30% and 50% less meat consumption could lead to reduction in water footprint by 6.9% and 7.5%, respectively, while 50% reduction in food waste at the consumption stage could save about 14% of water footprint. However, the synergistic effects of the two measures such as 30% less meat consumption and 50% food waste reduction, and 50% less meat consumption and 50% food waste reduction result to 20% and 24% reductions in water footprint, respectively. Moreover, our findings also showed that increasing food consumption with high environmental impacts could promote resources use inefficiency when waste occurs. Thus, policy strategies that address synergistic effects of both dietary change and food waste reduction should be strengthened to achieve sustainable food system. International and national policies can increase resource efficiency by utilizing all available reduction potentials while considering strategies interactions.

• 핵의학기술
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• 제23권2호
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• pp.29-37
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• 2019

DMIDR (General Electric Healthcare, USA)은 GE 사(社)의 최신 장비로써 PSF (Point Spread Function reconstruction), TOF(Time of Flight)와 Q.Clear의 적용이 가능하다. 특히, Q.Clear는 보정 알고리즘으로써 복셀(voxel)단위 신호 잡음 제거로 기존 OSEM (Ordered Subset Expectation Maximization)의 한계를 넘어설 수 있다. 따라서 이러한 재구성 및 보정 알고리즘의 성능 평가를 통해 정확한 SUV를 구현하며, 병변 검출 능력에 도움이 되는 알고리즘의 조합을 확인하고자 하였다. H/B(Hot & Background) Ratio 2:1, 4:1, 8:1의 비율로 NEMA/IEC 2008 PET phantom을 제작하였다. DMIDR의 NEMA test protocol을 이용하여 영상 획득을 하였다. 재구성 조합은 (1) VPFX(VUE point FX(TOF)), (2) VPHD-S(VUE point HD+PSF), (3) VPFX-S(TOF+PSF), (4) QCHD-S-400(VUE point HD+Q.Clear(${\beta}-strength$ 400)+PSF), (5) QCFX-S-400(TOF+Q.Clear(${\beta}-strength$ 400)+PSF), (6) QCHD-S-50(VUE point HD+Q.Clear(${\beta}-strength$ 50)+PSF), (7) QCFX-S-50(TOF+Q.Clear(${\beta}-strength$ 50) + PSF)의 7 가지로 구성하였다. H/B Ratio 및 재구성 알고리즘 별로 측정된 결과를 이용하여 CR (Contrast Recovery)와 BV (Background Variability)을 구하였다. 또한, 각 조합의 count를 측정하여 SNR (Signal to Noise Ratio)과 RC(Recovery Coefficient)를 구하고 SUV (Standardized Uptake Value)를 측정하였다. 구의 크기가 가장 작은 10 mm와 13 mm에서는 VPFX-S, 17 mm 이상에서는 QCFX-S-50에서 가장 높은 CR 결과를 보였다. BV와 SNR의 비교에서는 QCFX-S-400과 QCHD-S-400에서 좋은 값을 보였다. SUV 측정 결과는 H/B ratio와 비례하여 증감하는 양상을 보였다. SUV에 대한 RC의 경우 H/B ratio와 반비례하는 양상을 보였으며, 재구성 알고리즘 중에서는 QCFX-S-50이 가장 높은 값을 보였다. 또한, Q.Clear에 ${\beta}-strength$ 400이 적용된 재구성 알고리즘들이 낮은 값 분포를 보였다. Q.Clear가 적용된 재구성 조합은 ${\beta}-strength$를 높이면 신호잡음이 억제되어 영상 품질면에서 우수한 결과를 보였고 ${\beta}-strength$를 낮추면 선예도가 증가하며, partial volume effect가 감소하여 기존의 재구성 조건에 비하여 높은 RC에 근거한 SUV 측정이 가능하였다. 이러한 진보된 알고리즘의 사용으로 보다 정확한 정량화와 미세병변 검출능력을 향상 시킬 수 있으나 상관 관계를 고려하여 목적에 맞는 최적화 과정이 필요할 것으로 사료된다.

• 대한화장품학회지
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• 제42권3호
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• pp.235-245
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• 2016

본 연구에서는 히알루론산나트륨(sodium hyaluronate, HA)을 효소 분해하여 분자량 크기(1, 10, 50, 100, 660, 및 1500 kDa) 별로 제조한 뒤 콜라겐 합성 및 항염증 활성에 미치는 영향과 피부투과도를 조사하였다. 이들 HA는 인간피부세포인 Hs68 세포에 세포독성을 나타내지 않았다. 콜라겐 생합성능은 1500 kDa, 50, kDa HA가 각각 59, 50%로 콜라겐 생합성 촉진능이 우수한 것으로 나타났다. 분자량 크기에 따른 HA의 피부투과도를 측정한 결과 660 또는 1500 kDa의 HA은 2% 미만의 미미한 투과율을 보였으나, 저분자 HA (1, 10, 또는 50 kDa)은 시간이 지남에 따라 투과율이 증가하는 것을 확인하였다. 마우스 대식세포인 RAW 264.7 세포에서 HA 분자량 크기에 따른 항염증 효과를 확인한 결과, 50 kDa HA가 농도 의존적으로 nitric oxide 및 tumor necrosis factor-${alpha}$ 합성을 저해하여 다른 분자량의 HA (1, 10, 및 100 kDa)에 비해 가장 큰 항염증 효능을 나타냈다. 현재까지 효소(hyaluronidase) 처리하여 제조된 다양한 크기의 분자량(1, 10, 50, 100, 660, 1500 kDa)의 HA 중 50 kDa HA가 collagen의 합성, 항염증 및 피부 흡수도에 대한 종합적인 평가를 한 사례는 없었다. 따라서 이러한 연구결과는 50 kDa의 HA가 인간피부세포에서 콜라겐 합성을 증진시키고, 피부 투과율을 높으며 피부 주름을 유발하는 염증반응을 억제함으로써 피부노화 및 주름 개선용 화장품소재로 개발될 수 있는 가능성을 보여준다.

• Journal of Pharmaceutical Investigation
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• 제12권4호
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• pp.112-125
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• 1982

Sulfamethoxazole particles were microencapsulated using the gelatin-acacia complex coacervation method. Micromeritic properties and dissolution characteristics of the microcapsules were studied. The particle size distribution followed log-normal form. As the hardening time increased, the particle size and wall thickness increased ($45.3-52.0\;{\mu}m$, $2.02-5.12\;{\mu}m$, respectively). This is considered to be due to the cross-linked wall structure of formalized microcapsules which prevents shrinking of gelatin during the dehydration and drying processes. An increase of hardening time clearly delayed the release rate. The in vitro 50% dissolution time $(t_{50})$ for unencapsulated sulfamethoxazole powder was less than 3 min.; for microcapsules hardened for 30 min, the $t_{50}$ was 20.1 min.; for those hardened for 60 min. the $t_{50}$ was 25.0 min.; for those hardened for 120 min., the $t_{50}$ was 35.8 min. The surface of the unhardened microcapsules was smooth and had no cracking or pore penetration. However, the surface of the hardened microcapsules was folded and invaginated.

• 대한안전경영과학회지
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• 제16권2호
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• pp.63-70
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• 2014

As preventive measures have received tremendous attention to prevent any possible accident in advance, many work places have introduced safety and health management systems. However despite of this government's effort, the industrial accident rate of small-scale businesses with less than 50 employees does not decline, which is mainly because the projects are not differentiated according to the risk level of individual business. To evaluate the risk level of small-scale businesses with less than 50 employees and then establish effective safety and health management systems according to the risk level, this study has conducted the following processes. The small-scale businesses with less than 50 employees were evaluated through accident type, and potential accident risk factor was evaluated through location, business type, and business size. The results of this analysis are expected to make contribution to improving the effectiveness of the safety and health management supports to small-scale businesses with less than 50 employees.